LOCUS       NM_024184               1599 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus anti-silencing function 1B histone chaperone (Asf1b),
            mRNA.
ACCESSION   NM_024184
VERSION     NM_024184.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1599)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1599)
  AUTHORS   Wang,X., Wang,L., Dou,J., Yu,T., Cao,P., Fan,N., Borjigin,U. and
            Nashun,B.
  TITLE     Distinct role of histone chaperone Asf1a and Asf1b during
            fertilization and pre-implantation embryonic development in mice
  JOURNAL   Epigenetics Chromatin 14 (1), 55 (2021)
   PUBMED   34906203
  REMARK    GeneRIF: Distinct role of histone chaperone Asf1a and Asf1b during
            fertilization and pre-implantation embryonic development in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1599)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1599)
  AUTHORS   Ulmke,P.A., Sakib,M.S., Ditte,P., Sokpor,G., Kerimoglu,C., Pham,L.,
            Xie,Y., Mao,X., Rosenbusch,J., Teichmann,U., Nguyen,H.P.,
            Fischer,A., Eichele,G., Staiger,J.F. and Tuoc,T.
  TITLE     Molecular Profiling Reveals Involvement of ESCO2 in Intermediate
            Progenitor Cell Maintenance in the Developing Mouse Cortex
  JOURNAL   Stem Cell Reports 16 (4), 968-984 (2021)
   PUBMED   33798452
REFERENCE   5  (bases 1 to 1599)
  AUTHORS   Segura-Bayona,S., Knobel,P.A., Gonzalez-Buron,H., Youssef,S.A.,
            Pena-Blanco,A., Coyaud,E., Lopez-Rovira,T., Rein,K., Palenzuela,L.,
            Colombelli,J., Forrow,S., Raught,B., Groth,A., de Bruin,A. and
            Stracker,T.H.
  TITLE     Differential requirements for Tousled-like kinases 1 and 2 in
            mammalian development
  JOURNAL   Cell Death Differ 24 (11), 1872-1885 (2017)
   PUBMED   28708136
REFERENCE   6  (bases 1 to 1599)
  AUTHORS   Messiaen,S., Guiard,J., Aigueperse,C., Fliniaux,I., Tourpin,S.,
            Barroca,V., Allemand,I., Fouchet,P., Livera,G. and Vernet,M.
  TITLE     Loss of the histone chaperone ASF1B reduces female reproductive
            capacity in mice
  JOURNAL   Reproduction 151 (5), 477-489 (2016)
   PUBMED   26850882
  REMARK    GeneRIF: Loss of the histone chaperone ASF1B reduces female
            reproductive capacity.
REFERENCE   7  (bases 1 to 1599)
  AUTHORS   Canfield,C., Rains,J. and De Benedetti,A.
  TITLE     TLK1B promotes repair of DSBs via its interaction with Rad9 and
            Asf1
  JOURNAL   BMC Mol Biol 10, 110 (2009)
   PUBMED   20021694
  REMARK    GeneRIF: tousled-like kinases play important roles in DNA repair,
            not only by modulation of chromatin assembly via Asf1, but also by
            a more direct function in processing the ends of a tousled-like
            kinase via interaction with Rad9.
            Publication Status: Online-Only
REFERENCE   8  (bases 1 to 1599)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   9  (bases 1 to 1599)
  AUTHORS   Umehara,T. and Horikoshi,M.
  TITLE     Transcription initiation factor IID-interactive histone chaperone
            CIA-II implicated in mammalian spermatogenesis
  JOURNAL   J Biol Chem 278 (37), 35660-35667 (2003)
   PUBMED   12842904
REFERENCE   10 (bases 1 to 1599)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156028.2.
            
            On Nov 17, 2006 this sequence version replaced NM_024184.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003428.1, AK165322.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-244               AC156028.2         122405-122648
            245-360             AC156028.2         131742-131857
            361-537             AC156028.2         134545-134721
            538-1599            AC156028.2         135845-136906
FEATURES             Location/Qualifiers
     source          1..1599
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 40.22 cM"
     gene            1..1599
                     /gene="Asf1b"
                     /gene_synonym="1700003K02Rik; CIA-II"
                     /note="anti-silencing function 1B histone chaperone"
                     /db_xref="GeneID:66929"
                     /db_xref="MGI:MGI:1914179"
     exon            1..244
                     /gene="Asf1b"
                     /gene_synonym="1700003K02Rik; CIA-II"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..744
                     /gene="Asf1b"
                     /gene_synonym="1700003K02Rik; CIA-II"
                     /note="mCIA-II; anti-silencing function protein 1 homolog
                     B; ASF1 anti-silencing function 1 homolog B;
                     CCG1-interacting factor A-II"
                     /codon_start=1
                     /product="histone chaperone ASF1B"
                     /protein_id="NP_077146.1"
                     /db_xref="CCDS:CCDS22462.1"
                     /db_xref="GeneID:66929"
                     /db_xref="MGI:MGI:1914179"
                     /translation="MAKVSVLNVAVLENPSPFHSPFRFEISFECSEALSDDLEWKIIY
                     VGSAESEEFDQILDSVLVGPVPAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYH
                     GQEFIRVGYYVNNEYPDPELRENPPPKPDFSQLQRNILASNPRVTRFHINWDNNPDSL
                     EAIENQDPNVDFSLSLSCTPVKSLGLPSCIPGLLPENSMDCI"
     exon            245..360
                     /gene="Asf1b"
                     /gene_synonym="1700003K02Rik; CIA-II"
                     /inference="alignment:Splign:2.1.0"
     exon            361..537
                     /gene="Asf1b"
                     /gene_synonym="1700003K02Rik; CIA-II"
                     /inference="alignment:Splign:2.1.0"
     exon            538..1599
                     /gene="Asf1b"
                     /gene_synonym="1700003K02Rik; CIA-II"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1581..1586
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Asf1b"
                     /gene_synonym="1700003K02Rik; CIA-II"
                     /note="hexamer: AATAAA"
     polyA_site      1599
                     /gene="Asf1b"
                     /gene_synonym="1700003K02Rik; CIA-II"
                     /note="major polyA site"
ORIGIN      
        1 gctgagcgga ggagcgcttc agagggaaga gttgggagac gcagggaggt ttccgtcctg
       61 tcgtcccccc cttcttctct gtcgcaagtc actgtgaaga agtctccaca gcagctgcgg
      121 ctcccgggcg cggtgatggc caaggtgtcg gtgctgaatg tggctgtgct ggagaacccg
      181 agccctttcc acagcccctt ccggttcgag atcagcttcg aatgcagtga ggccctgtct
      241 gacgacctgg agtggaagat catttatgtg ggctcagctg agagtgagga gtttgatcag
      301 atcctagatt cagtgctggt gggccctgtc cctgcaggaa ggcatatgtt cgtctttcag
      361 gctgatgccc caaacccatc cctcattcct gagacggacg ccgtgggtgt gactgtggtt
      421 ctcatcacct gcacctacca tggacaagag ttcatccgtg tgggctacta tgtcaacaat
      481 gagtacccag acccagagct tcgagagaac ccacccccaa agccagactt ctctcagcta
      541 cagcggaaca tcttggcctc taacccccgg gtgacccgat tccatatcaa ctgggacaac
      601 aatccagaca gtctggaagc catagaaaac caggacccca atgtggactt cagcctttcc
      661 ctcagttgca ctcctgttaa aagcctgggc ctccctagtt gcatcccagg cctcctccct
      721 gagaactcca tggattgcat ctgacagggg agccaggtag agctcagtag gaccacagca
      781 gtctccttgc acacctggag gggacctaca agccctcagt cagacatgct tggtcatctc
      841 aaggatttgg ggaccaccag ctgtctccag atctgtcagc cccaagaaaa aacaatgggc
      901 cccaatctct tccatccagg tccagaagaa tcatctcact tatgacctac tgacctctaa
      961 aaagcaggta cttgtattgc tcattctatg cgtcattttt ctttatatat tatcagtttc
     1021 tatgagatgc tttctgaaca ccaccttctg tgaggcttgc ttgggcagtg tctggctagc
     1081 attggccaga ggttatcact ccttccaact ctagttcttg gggactaggc aaggaagaag
     1141 tcctagttcg aaggccagct caatacaatg gctatccttt cagagtgtct aggacattca
     1201 gtctaactag tactacaaaa cgcaaaagtg agctccccag gccaatgagg gatgtcaggt
     1261 actttggtca cagccacctt ttcatctcct gactgagcct ggctttctga gaggattgcc
     1321 ctaggtaggt atattggagg tcctgcttca tgcattctgg ccccatagag tcatcagggt
     1381 ttgctttgac cacatgttca ttctcatgct atacccaaat actctgggat aaaggaggtg
     1441 tttggcaggc tgacctgaaa aactcccatt ccatccacct ctatcctaag cccttagttc
     1501 ccttgctgct acatgtatgc tattgtgatt gcagtgtgta tattaaaagg ttttatatta
     1561 aaagttttgg ttgtcttaag aataaaagca cttcatcta
//
