LOCUS       NM_001170710            2170 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus ankyrin repeat and SOCS box-containing 8 (Asb8),
            transcript variant 2, mRNA.
ACCESSION   NM_001170710
VERSION     NM_001170710.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2170)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   2  (bases 1 to 2170)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   3  (bases 1 to 2170)
  AUTHORS   Liu,Y., Li,J., Zhang,F., Qin,W., Yao,G., He,X., Xue,P., Ge,C.,
            Wan,D. and Gu,J.
  TITLE     Molecular cloning and characterization of the human ASB-8 gene
            encoding a novel member of ankyrin repeat and SOCS box containing
            protein family
  JOURNAL   Biochem Biophys Res Commun 300 (4), 972-979 (2003)
   PUBMED   12559969
REFERENCE   4  (bases 1 to 2170)
  AUTHORS   Kile,B.T., Metcalf,D., Mifsud,S., DiRago,L., Nicola,N.A.,
            Hilton,D.J. and Alexander,W.S.
  TITLE     Functional analysis of Asb-1 using genetic modification in mice
  JOURNAL   Mol Cell Biol 21 (18), 6189-6197 (2001)
   PUBMED   11509662
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY240190.1, AK087299.1, AK030168.1 and AK016001.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1-3 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY240190.1, BC025106.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                BY240190.1         1-43
            44-262              AK087299.1         3-221
            263-770             AK030168.1         202-709
            771-1096            AK016001.1         825-1150
            1097-2170           AK030168.1         1036-2109
FEATURES             Location/Qualifiers
     source          1..2170
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 54.13 cM"
     gene            1..2170
                     /gene="Asb8"
                     /gene_synonym="4930539L19Rik; C430011H06Rik"
                     /note="ankyrin repeat and SOCS box-containing 8"
                     /db_xref="GeneID:78541"
                     /db_xref="MGI:MGI:1925791"
     exon            1..102
                     /gene="Asb8"
                     /gene_synonym="4930539L19Rik; C430011H06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            103..266
                     /gene="Asb8"
                     /gene_synonym="4930539L19Rik; C430011H06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             138..1004
                     /gene="Asb8"
                     /gene_synonym="4930539L19Rik; C430011H06Rik"
                     /note="ankyrin repeat and SOCS box-containing protein 8;
                     ASB-8"
                     /codon_start=1
                     /product="ankyrin repeat and SOCS box protein 8"
                     /protein_id="NP_001164181.1"
                     /db_xref="CCDS:CCDS27787.1"
                     /db_xref="GeneID:78541"
                     /db_xref="MGI:MGI:1925791"
                     /translation="MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGG
                     ADVNCTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVE
                     VLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAM
                     KGNLESVSILLDYGAEVRVINLKGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGQF
                     ELRKNGIMPREVTKDQQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPL
                     PVSLKDYLLLLE"
     exon            267..371
                     /gene="Asb8"
                     /gene_synonym="4930539L19Rik; C430011H06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            372..2170
                     /gene="Asb8"
                     /gene_synonym="4930539L19Rik; C430011H06Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcggccggct tgcgctgtaa accccggggc tgatgcgagc cgcttctgct tccgggtcac
       61 gccttgacag cggcttcccg gaccgatctg acccgcggtt cggcagtttg gagcatgtga
      121 acacactctg agccttgatg agttccagca tgtggtatat tatgcagagc attcagagca
      181 aatactccct ctccgaacgc ctgatccgaa ccatcgctgc catccgctcc ttcccacatg
      241 acaacgtaga ggacctcatc agagggggag cagatgtgaa ctgcacgcac ggcacactga
      301 agcccctcca ctgtgcctgc atggtgtccg acgccgactg cgtagagctc ctcctggaga
      361 agggagcaga ggtcaatgcc ctggatggtt acaaccgaac ggccctccac tatgcagcag
      421 agaaagatga ggcttgtgtg gaggtcctac tggagtatgg ggcaaacccc aatgcactgg
      481 acggcaacag agacaccccg cttcattggg cagcctttaa gaacaatgct gagtgtgtgc
      541 gggctctcct ggagagcggg gcctccgtca atgccctgga ttacaacaac gatacgccgc
      601 tcagctgggc tgccatgaag ggaaatcttg agagtgtcag catccttctt gattatggtg
      661 ctgaggtcag agtcatcaac ttaaaaggcc agacacccat ctcccgcctg gtggctctgc
      721 tagtgagagg acttggaaca gaaaaagaag actcctgctt tgagctcctc catagagctg
      781 ttggacagtt tgaattaagg aaaaacggca tcatgccccg agaagtgacc aaagaccagc
      841 agctgtgtga aaaactgact gtgttgtgct cagcaccagg gacgcttaaa accctcgccc
      901 gctatgctgt gcgccgtagc ctcggtctcc agtacctgcc cgacgcagtg aagggtctcc
      961 cactgccagt gtctttgaag gactacctgt tactcttgga gtagcttgga ggaggcattg
     1021 ctgccgtcat gcggacggct ttgggtgagg cttccttgcc atcctgtctc tttgttgtca
     1081 acacagaaaa gaaggtgttc ctgctgtgtg gtttatagat ttgaggcaac acataacagt
     1141 gacttatgca tcgcctcccc tcccatccca agcaaccaaa ccaaaaccat ttacctcact
     1201 tgtttgccgt gttattgctt agttgctttt ttatattcag ccctgcaaaa gaagtcttcc
     1261 ccggatccct taggcacttc agtcaccagt gtaacccatt tcctaggaag atgtcacgtt
     1321 ctcagagtgc acagttccct ttggggccgt gctgtagcac ggtgacagag ttccttctga
     1381 aaagttctag ttgatatgac agctaacaaa tgaaccccca gttaacaaga attatgctcc
     1441 aaggatgagt gcttgaactt caggtgctgt gtagacacag aatttggcat tcaggagcac
     1501 ttccatatgg tacccagggg ctagtcatcc agtaggtggg acttcacccg gatatctggc
     1561 tgttcccctt aaaaagaaac actacttccc agcagtccca gaactgccag gccatccttc
     1621 taatgtggct ctttccctga aaagtcctgt cactaatgag ctgagcgagc atcccagcat
     1681 ccccgcacct cggatgaagg tctctctagt aggggtgggg gccattgggc ctcactgccc
     1741 tgtccacaga gcttcattcc ttacgagttt gcattttggt tttgtttgtt tgtttgtttt
     1801 tgtttttgtt tttttcctac tctcttggaa cctttgcttt tttattgagc tgtagaagat
     1861 ggtggggtaa gtggggctgg ggacagaata caaaagaggt tctttggaac tggccttgcc
     1921 taccctaaaa agacccattt ctgtgaacaa agctcctctt tttgtgtcct taaactagat
     1981 gaagttgatt ttgaccttaa gtgatctgta tgcaagttgg aaagcacttt ttaaaaagct
     2041 ggctggagac tacacccaaa tgaataggac cttctgacgc agctaactca aaaacgtgtg
     2101 cctgcttttg ttctttctgt tgctgggatt tgcccatttg aaaaaagaat aaataaataa
     2161 ttctaaaagc
//
