LOCUS       NM_001355134            1457 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ankyrin repeat and SOCS box-containing 18 (Asb18),
            transcript variant 2, mRNA.
ACCESSION   NM_001355134 XM_006529296
VERSION     NM_001355134.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1457)
  AUTHORS   Kile,B.T., Schulman,B.A., Alexander,W.S., Nicola,N.A., Martin,H.M.
            and Hilton,D.J.
  TITLE     The SOCS box: a tale of destruction and degradation
  JOURNAL   Trends Biochem Sci 27 (5), 235-241 (2002)
   PUBMED   12076535
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC145621.1.
            
            On Sep 8, 2017 this sequence version replaced XM_006529296.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC141295.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849375,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1457              BC145621.1         1-1457
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 45.06 cM"
     gene            1..1457
                     /gene="Asb18"
                     /gene_synonym="Asb-18"
                     /note="ankyrin repeat and SOCS box-containing 18"
                     /db_xref="GeneID:208372"
                     /db_xref="MGI:MGI:2655109"
     exon            1..294
                     /gene="Asb18"
                     /gene_synonym="Asb-18"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..1370
                     /gene="Asb18"
                     /gene_synonym="Asb-18"
                     /note="isoform 2 is encoded by transcript variant 2;
                     ankyrin repeat and SOCS box protein 18; SOCS box protein
                     ASB-18"
                     /codon_start=1
                     /product="ankyrin repeat and SOCS box protein 18 isoform
                     2"
                     /protein_id="NP_001342063.1"
                     /db_xref="GeneID:208372"
                     /db_xref="MGI:MGI:2655109"
                     /translation="MSSWDSPPDYPLSSDIVRRLKSALATGDEDTVQKLICTEVEPVD
                     AVIELANDDWMKEPSAELPTGVLLGLWTLEYQRELTTPLCIAAAHGHESCVRHLLSRK
                     ADPNASPGGRGALHEACLGNHTACARLLLQHGADPDLLNSEGLAPLHLCRTPASLGCA
                     RELLEHGATVQLEGGPGRDTPLHVAAQRGLDEHAQLYLGFGARVDARNGRGETALSAA
                     CGAAARSPDEHARCLRLCALLLRGGAAADARDEDERSPLHKACGHARPGLCTLLLRHG
                     ADAGALDYGGASPLARALQTATCAPPTAPQRTVQVLLNHGSRSVWPDAFPKVLRTCAQ
                     VPEVIEVLFNSYTQLPVSESWREAIPEEVYQMHKPFYRSLFALAHTPRCLQHLCRCTI
                     RKLFGKESVHLVPQLPLPETLQNYLLLEPEGVLC"
     exon            295..562
                     /gene="Asb18"
                     /gene_synonym="Asb-18"
                     /inference="alignment:Splign:2.1.0"
     exon            563..1070
                     /gene="Asb18"
                     /gene_synonym="Asb-18"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1184
                     /gene="Asb18"
                     /gene_synonym="Asb-18"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1457
                     /gene="Asb18"
                     /gene_synonym="Asb-18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catctgtcct gctctgggga cagggctaac tttgggcatg cattagagga agagaagaag
       61 gctggccctg cacagggaga gataccacaa tgtccagctg ggactcgccc ccagattacc
      121 ccctcagctc agacatagtg aggagattaa agtctgctct ggccactggg gacgaggaca
      181 ctgtacagaa gctgatctgc actgaggtgg agcctgtgga cgccgtaata gaacttgcta
      241 atgatgactg gatgaaggag ccctcagccg agctgcccac gggcgtactg ctaggccttt
      301 ggaccctgga gtaccagcgg gagctcacca caccgctgtg catcgctgcg gcccacggcc
      361 acgagtcctg cgtgcgacac ctgctcagtc gcaaagctga tcccaatgcc agtcccggag
      421 gtcgtggtgc cctacatgag gcctgtctcg ggaaccatac cgcctgcgcc cgactgctgc
      481 tgcagcacgg agcagatcca gatctgctca actccgaggg cctggcaccc ctgcacctat
      541 gccgcacacc cgcctcgctt gggtgcgctc gggagctgct ggagcacggc gcgacagtcc
      601 agctggaggg tggccctggc cgagacacac cgctgcacgt ggcggcccag cgcggcctgg
      661 acgagcacgc gcaactctac ctgggcttcg gcgcgcgagt ggacgcgagg aacggccggg
      721 gcgaaacggc ccttagcgca gcatgcggag cggcggcgcg gagccccgac gagcacgcgc
      781 gctgcctgcg cctgtgcgcg ctccttctgc gcggcggcgc ggcggcagac gcgcgtgacg
      841 aggacgagcg cagcccgctg cacaaggcct gcggccacgc gcgccccggc ctgtgcacgc
      901 tcctgctgcg gcacggcgcc gacgcgggcg cgctcgacta tggtggcgcg tccccgctgg
      961 cgcgcgcgct gcagacggcc acgtgcgcgc ccccgacagc gccgcagcgc acggtccagg
     1021 tgctactaaa tcacggatcc cgctccgtgt ggcctgatgc cttccccaag gttctgagga
     1081 catgtgcaca ggtgcctgaa gtcattgaag ttctgttcaa ctcctacact cagctcccag
     1141 tgtctgagtc ctggcgggaa gccatccctg aagaagtata ccagatgcac aagcctttct
     1201 acaggtctct cttcgccttg gcacacaccc cgcgctgcct gcagcacctt tgccgctgta
     1261 ctatccgaaa actcttcggc aaggagagcg ttcaccttgt gccccagcta ccattacctg
     1321 agactctgca aaattacctg cttttggagc cagagggtgt tttgtgttga aaccacagcc
     1381 ttggggccca ggttcttctc tgcatcttcc cctttctgca gaggttctat gtgagggaca
     1441 gaaccctggt atggggg
//
