LOCUS       NM_178283               2410 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus ankyrin repeat and SOCS box-containing 13 (Asb13),
            transcript variant 1, mRNA.
ACCESSION   NM_178283 NM_080857
VERSION     NM_178283.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2410)
  AUTHORS   Kile,B.T., Schulman,B.A., Alexander,W.S., Nicola,N.A., Martin,H.M.
            and Hilton,D.J.
  TITLE     The SOCS box: a tale of destruction and degradation
  JOURNAL   Trends Biochem Sci 27 (5), 235-241 (2002)
   PUBMED   12076535
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129597.5 and AK078289.1.
            
            On or before Jun 15, 2012 this sequence version replaced
            NM_080857.2, NM_178283.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC018240.1, AK078289.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                AC129597.5         83153-83198         c
            47-1795             AK078289.1         3-1751
            1796-2410           AC129597.5         65451-66065         c
FEATURES             Location/Qualifiers
     source          1..2410
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 2.03 cM"
     gene            1..2410
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /note="ankyrin repeat and SOCS box-containing 13"
                     /db_xref="GeneID:142688"
                     /db_xref="MGI:MGI:2145525"
     exon            1..144
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..938
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ankyrin repeat and SOCS box protein 13; ankyrin repeat and
                     SOCS box-containing protein 13; ankyrin repeat
                     domain-containing SOCS box protein 13"
                     /codon_start=1
                     /product="ankyrin repeat and SOCS box protein 13 isoform
                     1"
                     /protein_id="NP_840068.1"
                     /db_xref="CCDS:CCDS36582.1"
                     /db_xref="GeneID:142688"
                     /db_xref="MGI:MGI:2145525"
                     /translation="MEPRAGDGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIDSGAC
                     VNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVK
                     LLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAR
                     EHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKP
                     SDYTWSSSAPAKCFEYYEKTPLSLSQLCRVSLRKATGVRGLEKVAKLNIPPRLIDYLS
                     YN"
     exon            145..332
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /inference="alignment:Splign:2.1.0"
     exon            333..483
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /inference="alignment:Splign:2.1.0"
     exon            484..618
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /inference="alignment:Splign:2.1.0"
     exon            619..810
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /inference="alignment:Splign:2.1.0"
     exon            811..2410
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2386..2391
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /note="hexamer: AATAAA"
     polyA_site      2405
                     /gene="Asb13"
                     /gene_synonym="2210015B19Rik; 6430573K02Rik; Asb-13"
                     /note="major polyA site"
ORIGIN      
        1 cggcctgcgc tccggggtag gtctcggttt aggtcccggc tcaggtccca gagctctgag
       61 tcacaaggcc ggtagacagg ggagcccagc gggcgagcag catggagccg cgcgccgggg
      121 acggctgctt cctgggagat gtgggtttct gggtggagcg cacgcccgtt catgaggcgg
      181 ctcagcgggg tgagagcctc cagcttcagc agctgattga cagtggagca tgtgttaacc
      241 aggtcactgt ggactcgatc acaccccttc atgcagcaag tctgcagggc caggcccagt
      301 gtgtgcagct gctgctagca gctggtgccc aggtggacgc acgcaacatt gacggcagca
      361 cccctctttg tgatgcctgt gcctcaggca gcattgagtg tgtgaagctc ttgctgtcct
      421 atggggcgaa agtcaaccct cctttgtaca cagcatcccc gctacacgag gcctgcatga
      481 gtgggagttc tgaatgcgtg aggcttctta ttgatgttgg ggccaacctg gaagcccacg
      541 attgccattt tgggacgcct ttacatgttg cctgtgcccg ggagcatttg gactgtgtca
      601 aagtgttgct caatgcaggg gccaatgtga acgcagccaa acttcatgag actgcgcttc
      661 atcatgcagc caaggtaaag aacgttgacc tcatcgagat gctcatagag tttggaggca
      721 acatctatgc ccgggacaac cggggcaaga agccctcgga ctacacgtgg agcagcagcg
      781 ccccggccaa gtgctttgag tactatgaaa agacacctct tagcctctcc cagctctgca
      841 gggtgagcct gaggaaggcc accggtgtcc gaggactaga gaaagtcgcc aagttgaaca
      901 tccctccccg gctcatcgac tacctttcct acaactgagc tgcaggcagg ggccggaaag
      961 gctgatggct ggcccagtta tcaccttgct ttgcctagcc ctgggcatgg tatgagttct
     1021 gcctgtttct ctgaaacact aacattgctg tagattggtt gatgctcctt catgttcctt
     1081 ctggttgtcc tttttgatgt cttcttctga acccagagaa gatctctgaa gccccagaag
     1141 gccagtgtct ggcatcacag ttgtggatgt aacccttgct agtctcctgg aacaaatgta
     1201 gtcattctag gacaggctca gttctctgtg tttctctttt caccggccac cctcaaatag
     1261 agacagttca aggtgcacag gggaatctgg gggctcagaa tgctgatgtc gatggttttt
     1321 atctgggtgc catgccacag aagcatcagg ttctaagcac ttgaccctgt ggactgggac
     1381 actactctgc tggcatcgtg ccatttggat ggtttttctg gggcagcagc tggcactttc
     1441 caaggtctac ctgtacccag gtatatcact caggggcttt acagatcaga gtttgtaccc
     1501 ccacatcaag cactgttttg ggggggggcg gggatgactg tctccaatat taggactcaa
     1561 atctgttaaa aaaagtttat gttgggagcc tggagagata gcttggggct agagtttagt
     1621 ttccagaacc cacataaggc agcttacaat ggcccattac ttcagctcca ggggatccaa
     1681 caccctcttc tggcctcctc aagcactcag acatgtatgt gtatacacac acacacacac
     1741 acacacacac acacacacag agagagagag agagagagag agagagagag agagagagat
     1801 aaataaaata aaatctttta aaaagttgga gaccctttag attatatata gatgtgtata
     1861 tatatatata tacacataca ttcatgtata tgctgtaaca agatttgcaa tgcaaacaat
     1921 ataaacaata gctaatatga aagtgcaaaa ctttatccag atgggaatga gattctttag
     1981 ccaaagcaga aaaaggggtc acaatttctt cctatagtaa taacaatgag tcctgtacat
     2041 tgtgggtgaa atactaagtc ttgcattcag actgaatttt ccggattgac attctatatt
     2101 ttaacaatac tgataatacc ccacatacaa tagaaagaat tagagaattt tccagtagtc
     2161 attctctact gagaaaagcc accttccttc tgtcagtctc tggtacaagt tctgaggaaa
     2221 tccatgtttt tgcatggaat agtaatagca gttattttca gaaaggcact ggagtctgcc
     2281 tctttcgtct ttgtaacaga atcttgcctc tagcaataaa acccaataac agcccatctg
     2341 ctatatcttt tggtagagaa taaggttttc tcaccattat tgtccaataa aagtggttgg
     2401 atgaagtttg
//
