LOCUS       NM_080444               2327 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus ankyrin repeat and SOCS box-containing 10 (Asb10),
            transcript variant 1, mRNA.
ACCESSION   NM_080444
VERSION     NM_080444.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2327)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2327)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2327)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 2327)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 2327)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 2327)
  AUTHORS   Kile,B.T., Metcalf,D., Mifsud,S., DiRago,L., Nicola,N.A.,
            Hilton,D.J. and Alexander,W.S.
  TITLE     Functional analysis of Asb-1 using genetic modification in mice
  JOURNAL   Mol Cell Biol 21 (18), 6189-6197 (2001)
   PUBMED   11509662
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC116136.9, AK028538.1 and AK052929.1.
            
            On Jul 14, 2015 this sequence version replaced NM_080444.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028538.1, AF398971.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                AC116136.9         153100-153110
            12-94               AK028538.1         3-85
            95-1835             AK052929.1         2-1742
            1836-1849           AK028538.1         1827-1840
            1850-2327           AK028538.1         1842-2319
FEATURES             Location/Qualifiers
     source          1..2327
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 11.93 cM"
     gene            1..2327
                     /gene="Asb10"
                     /gene_synonym="Asb-10"
                     /note="ankyrin repeat and SOCS box-containing 10"
                     /db_xref="GeneID:117590"
                     /db_xref="MGI:MGI:2152836"
     exon            1..424
                     /gene="Asb10"
                     /gene_synonym="Asb-10"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..1512
                     /gene="Asb10"
                     /gene_synonym="Asb-10"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ankyrin repeat and SOCS box protein 10"
                     /codon_start=1
                     /product="ankyrin repeat and SOCS box protein 10 isoform
                     1"
                     /protein_id="NP_536692.1"
                     /db_xref="CCDS:CCDS19124.1"
                     /db_xref="GeneID:117590"
                     /db_xref="MGI:MGI:2152836"
                     /translation="MLMSWSPEECRDQGEPQGDRYSLCAKLVEKPDRGSEEHLEPGLG
                     PIIIRSASGPTLAFWQAVLVGDVGSVSRILSDSSTGLAPDSIFDTSDPERWRDYRFNI
                     RALRLWSLTYEEELTTPLHVAASRGHTEVLELLLRRRAKPDSAPGGRTALHEACSAGH
                     AACVRVLLVAGADPNTLDQDGKRPLHLCRGPGILECVELLLKFGAQVDGRTEDEEETP
                     LHIAARLGHVELADLLLRWGACPDVRNSEGWTPLLAACDIRCQSPKDAEATTNRCFQL
                     CRLLLSVGADADAANQDKQRPLHLACRHGHSAVVQLLLSCGVNANAMDYGGHTPLHCA
                     LLGPTTAVAHSPEHTVRDLLNHGAVRVWPGALPKVLDRWCMSPRTIEVLMNTYRVVQL
                     PEEAKGLVPPEILQKYHGFYSSLFALVRQPRSLQHLCRCALRSHLEGCLPHALPRLPL
                     PPRMLRFLQLDFEDLLY"
     exon            425..692
                     /gene="Asb10"
                     /gene_synonym="Asb-10"
                     /inference="alignment:Splign:2.1.0"
     exon            693..1212
                     /gene="Asb10"
                     /gene_synonym="Asb-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1326
                     /gene="Asb10"
                     /gene_synonym="Asb-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1512
                     /gene="Asb10"
                     /gene_synonym="Asb-10"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..2327
                     /gene="Asb10"
                     /gene_synonym="Asb-10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gattgggctc cagagaggga cacgggacct ctgcctgtgg ttctctcctt ccgttctctc
       61 tgcctgtagc cttttcctct tcccttctga gactatccct ttccccatat gctcatgagt
      121 tggtccccag aggagtgcag ggaccaggga gagcctcagg gtgacagata cagcctgtgt
      181 gccaagctgg tagagaagcc tgatagaggg tctgaggagc accttgagcc tggcctggga
      241 cctatcatca tccgctcggc ttcaggaccc acccttgcct tctggcaggc agtacttgtt
      301 ggggatgtgg gctctgtctc tcgaatcctc tcggactcca gcactggtct ggctcccgat
      361 tccatctttg ataccagcga cccagagcga tggagagatt accgcttcaa catccgtgct
      421 ttgagactct ggtctctgac atatgaagag gagctgacca ctccactgca tgtggcagcc
      481 agccgtggcc acactgaagt tcttgagttg ctgctgaggc gtcgagccaa gccggacagt
      541 gcccccgggg gccgcactgc actgcatgag gcctgttctg caggtcatgc tgcctgtgtc
      601 cgtgtgctgt tggtggctgg agcagacccc aacaccctgg accaggatgg caaacgccct
      661 ttgcatctct gccgggggcc tggtatcctc gagtgtgtgg agttgctcct gaagtttgga
      721 gcacaagtgg atggtcggac tgaagatgaa gaagagaccc ctctgcacat agctgcccgg
      781 cttggccatg tggaactagc agatctgctt ctgagatggg gtgcgtgtcc tgatgtccgc
      841 aattctgaag gttggacacc actgctggct gcctgtgaca tccgctgtca atccccaaag
      901 gatgctgagg ccaccaccaa ccgctgtttt caactgtgcc gcttgctgct gtctgtgggg
      961 gcagatgctg atgccgccaa ccaggacaag cagcggcccc tgcacctggc ctgccgccac
     1021 ggccactcag ctgttgtaca gctgctcctg tcctgtggtg tcaacgctaa tgccatggac
     1081 tacgggggac acacgcctct gcactgtgct ctgctcggtc caactacagc agtggcccac
     1141 agccctgagc acacagtgcg agatctactc aatcacggtg ctgtccgagt ctggccaggg
     1201 gcactcccca aggtgctgga tcgctggtgc atgtccccac ggaccatcga ggtcctgatg
     1261 aatacatacc gtgtagttca gcttcctgag gaggccaagg gcttggtgcc accagagatt
     1321 ctacagaagt accatggatt ctactcttcc ctctttgcct tggtgaggca gcccaggtcg
     1381 ctgcagcatc tctgccgttg tgcgctccgc agtcacctgg agggctgtct gccccatgca
     1441 ctaccgcgcc ttcccctgcc accgcgcatg ctccgctttc tgcagctgga ctttgaggat
     1501 ctgctctact aggcttgctg ccctgtgaac aaagcagacc ccacccccac cccaagggca
     1561 tctctcagca atgaatgatg caaggcggtc tgtcttcaag tcaggagtgg acgccttgat
     1621 ccacacttga gagaagaggc cagatcagca cccggctggt agtgatgcag agggcacctg
     1681 tgcagatctg tgtgcgcact ggaaatctct aggctgaagc ccagagcaat ggtgcaggtg
     1741 ttagtccttg ggaggcagag acaggagggt ggagagaggc agagacagga gggtggagag
     1801 tggccacatt gtgctatgtg gtgagaattt gtcttaaaaa aaaaaaaaag tctacagttt
     1861 gtgtgatttg gtactgtctc cagcaagcct ccatctgcct ggatgtgact ccctcacaca
     1921 gaatcagggt aggttaggcc ttgtgcaagc tgcctcactg ctcccttcag tactcagtaa
     1981 caggtcccag gccaacctgc ctcctctcct cacatgcagt ggttaatagc ctctagagtg
     2041 agaacttgtc agaacaggtg gcctgaaggg tgggtgggca agacagaggt gtgtgtaaag
     2101 agaagctggt ggtcaggggc tggagatggg aaagcccctg ggacagggtt cacagatgtg
     2161 gaagacaaag taacccccgg cttggatgag gatggggccc tctgcatggt taagaaaaca
     2221 accatttctc cactgctcat gccacctata ggtctggaag catcactcag tgcacatctg
     2281 gctcttgttc tttttaatct gctttattaa attttctatg taagtgt
//
