LOCUS       NM_028809               1305 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus actin related protein 2/3 complex, subunit 5-like
            (Arpc5l), transcript variant 1, mRNA.
ACCESSION   NM_028809
VERSION     NM_028809.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1305)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1305)
  AUTHORS   Olthof,A.M., White,A.K., Mieruszynski,S., Doggett,K., Lee,M.F.,
            Chakroun,A., Abdel Aleem,A.K., Rousseau,J., Magnani,C.,
            Roifman,C.M., Campeau,P.M., Heath,J.K. and Kanadia,R.N.
  TITLE     Disruption of exon-bridging interactions between the minor and
            major spliceosomes results in alternative splicing around minor
            introns
  JOURNAL   Nucleic Acids Res 49 (6), 3524-3545 (2021)
   PUBMED   33660780
REFERENCE   3  (bases 1 to 1305)
  AUTHORS   Biesemann,C., Gronborg,M., Luquet,E., Wichert,S.P., Bernard,V.,
            Bungers,S.R., Cooper,B., Varoqueaux,F., Li,L., Byrne,J.A.,
            Urlaub,H., Jahn,O., Brose,N. and Herzog,E.
  TITLE     Proteomic screening of glutamatergic mouse brain synaptosomes
            isolated by fluorescence activated sorting
  JOURNAL   EMBO J 33 (2), 157-170 (2014)
   PUBMED   24413018
REFERENCE   4  (bases 1 to 1305)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL844588.17.
            
            On Mar 23, 2023 this sequence version replaced NM_028809.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024482.1, AK008255.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-235               AL844588.17        68078-68312
            236-308             AL844588.17        73083-73155
            309-485             AL844588.17        73691-73867
            486-1305            AL844588.17        75026-75845
FEATURES             Location/Qualifiers
     source          1..1305
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 24.42 cM"
     gene            1..1305
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
                     /note="actin related protein 2/3 complex, subunit 5-like"
                     /db_xref="GeneID:74192"
                     /db_xref="MGI:MGI:1921442"
     exon            1..235
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..548
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
                     /note="isoform a is encoded by transcript variant 1;
                     actin-related protein 2/3 complex subunit 5-like protein;
                     arp2/3 complex 16 kDa subunit 2"
                     /codon_start=1
                     /product="actin-related protein 2/3 complex subunit 5-like
                     protein isoform a"
                     /protein_id="NP_083085.1"
                     /db_xref="CCDS:CCDS38120.1"
                     /db_xref="GeneID:74192"
                     /db_xref="MGI:MGI:1921442"
                     /translation="MARNTLSSRFRRVDIDEFDENKFVDEHEEAAAAAGEPGPDPCEV
                     DGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDR
                     NGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV"
     exon            236..308
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
                     /inference="alignment:Splign:2.1.0"
     exon            309..485
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
                     /inference="alignment:Splign:2.1.0"
     exon            486..1305
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      993..998
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
                     /note="hexamer: AATAAA"
     polyA_site      1018
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
                     /note="major polyA site"
     regulatory      1282..1287
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
                     /note="hexamer: AATAAA"
     polyA_site      1305
                     /gene="Arpc5l"
                     /gene_synonym="2010015J01Rik; ARC16-2"
ORIGIN      
        1 gcttcccgcc cccaagcgga gccggtgcgg aggggagccg ggaaagagcg aagcctaggc
       61 ggctgagtgg ccgccgcgct cccgccatgg cccggaacac actgtcctca cgcttccgcc
      121 gcgtggatat cgacgaattt gacgagaaca aattcgtaga cgagcacgaa gaggcagcgg
      181 cggcggcggg cgagccaggc cccgacccct gcgaggtaga cgggctcctg cggcaagggg
      241 acatgcttcg ggcgttccat gcagctttgc ggaactcacc aatcaacacc aagaatcaag
      301 ctgtgaagga acgagcccag ggtgtagtcc tgaaagtact cacaaacttt aagagcagcg
      361 aaattgagca ggctgtgcag tcactggaca gaaatggcat tgatttgcta atgaagtaca
      421 tttataaagg gtttgagaag cctacagaaa atagcagtgc agtgctactc cagtggcatg
      481 aaaaggcctt agctgtagga ggactaggct ccattataag agttcttaca gcaagaaaga
      541 ctgtttaaaa aaaaatcctg ttaccttgag aagaattttg gatgcccagg ctggtgaaga
      601 agggactgac aatggaccat cttcctagaa ctcccaacta aatacttcag gacacatctt
      661 ctggaatgta ttttactttt gaggtggagg gagaaattgt cttattgatt cctaaattct
      721 ttgcaggatc agaatgtctg cctttgtcta cagagttaac acagaaccaa cacttgacta
      781 tcaggctgac tggccagatt atgtcaggtg tacctgtgag cactgtctgt ttgaaatggg
      841 gagggactgt ttgggcaggt gcagatccac aggctgtggt gaaaaggaga gcttgggttc
      901 tgaagcggaa aaacctgaga gtttgtacag acatcctgtc ttctcagaga agacaggctc
      961 tcttgggttc attgtaaagt gcctgctgca tcaataaagc tcttggctta ttagtctatt
     1021 catcgcggtg tgttctctgt atgttaagtg ggaaaagaaa gggttagtaa tgaatgatga
     1081 tagttgggtt tggaaagctg atgtagaagg agtacaggtg tccctgtcct gccatccctg
     1141 ggggaggggg aaagcaagca gggcgacgac acagctgtgc catatttcaa ctacagaggt
     1201 gctggatgct accgagagac cttttgctga gtgtttattt ttcttactct tttgatttgt
     1261 atgtaatttt ggagcttatt taataaagtg ccaaaccttt aatga
//
