LOCUS       NM_001166397            3683 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus armadillo repeat containing, X-linked 2 (Armcx2),
            transcript variant 2, mRNA.
ACCESSION   NM_001166397
VERSION     NM_001166397.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3683)
  AUTHORS   Izquierdo-Villalba,I., Mirra,S., Manso,Y., Parcerisas,A., Rubio,J.,
            Del Valle,J., Gil-Bea,F.J., Ulloa,F., Herrero-Lorenzo,M.,
            Verdaguer,E., Beninca,C., Castro-Torres,R.D., Rebollo,E.,
            Marfany,G., Auladell,C., Navarro,X., Enriquez,J.A., Lopez de
            Munain,A., Soriano,E. and Aragay,A.M.
  TITLE     A mammalian-specific Alex3/Galphaq protein complex regulates
            mitochondrial trafficking, dendritic complexity, and neuronal
            survival
  JOURNAL   Sci Signal 17 (822), eabq1007 (2024)
   PUBMED   38320000
REFERENCE   2  (bases 1 to 3683)
  AUTHORS   Zhou,J., McCarrey,J.R. and Wang,P.J.
  TITLE     A 1.1-Mb segmental deletion on the X chromosome causes meiotic
            failure in male mice
  JOURNAL   Biol Reprod 88 (6), 159 (2013)
   PUBMED   23677977
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3683)
  AUTHORS   Lopez-Domenech,G., Serrat,R., Mirra,S., D'Aniello,S., Somorjai,I.,
            Abad,A., Vitureira,N., Garcia-Arumi,E., Alonso,M.T.,
            Rodriguez-Prados,M., Burgaya,F., Andreu,A.L., Garcia-Sancho,J.,
            Trullas,R., Garcia-Fernandez,J. and Soriano,E.
  TITLE     The Eutherian Armcx genes regulate mitochondrial trafficking in
            neurons and interact with Miro and Trak2
  JOURNAL   Nat Commun 3, 814 (2012)
   PUBMED   22569362
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3683)
  AUTHORS   Smith,C.A., McClive,P.J. and Sinclair,A.H.
  TITLE     Temporal and spatial expression profile of the novel
            armadillo-related gene, Alex2, during testicular differentiation in
            the mouse embryo
  JOURNAL   Dev Dyn 233 (1), 188-193 (2005)
   PUBMED   15759267
  REMARK    GeneRIF: has a role in specification or development of the
            interstitial cell lineage in the developing testis
REFERENCE   5  (bases 1 to 3683)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK172960.1 and BE986475.1.
            
            Transcript Variant: This variant (2) lacks 5' UTR sequence,
            compared to variant 1. Variants 1, 2, and 3 encode the same
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK172960.1, AK014329.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3564              AK172960.1         1-3564
            3565-3683           BE986475.1         1-119               c
FEATURES             Location/Qualifiers
     source          1..3683
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 56.27 cM"
     gene            1..3683
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /note="armadillo repeat containing, X-linked 2"
                     /db_xref="GeneID:67416"
                     /db_xref="MGI:MGI:1914666"
     exon            1..303
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /inference="alignment:Splign:2.1.0"
     exon            304..568
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /inference="alignment:Splign:2.1.0"
     exon            569..673
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /inference="alignment:Splign:2.1.0"
     exon            674..733
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /inference="alignment:Splign:2.1.0"
     exon            734..799
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /inference="alignment:Splign:2.1.0"
     exon            800..3671
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /inference="alignment:Splign:2.1.0"
     CDS             931..3285
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /codon_start=1
                     /product="armadillo repeat-containing X-linked protein 2"
                     /protein_id="NP_001159869.1"
                     /db_xref="CCDS:CCDS30401.1"
                     /db_xref="GeneID:67416"
                     /db_xref="MGI:MGI:1914666"
                     /translation="MSRARDAGCVAAGIVIGASAWYCVYKYTRGKDQKKKRLTKPKNR
                     ASVGTGSRARAGLRAGFTIDLGPGFSPPNPVDIEIMNKAQGEASNLATTVAEEVAPAA
                     PSPKVQNGAESKVQELNGAKTEANLESVVMPSATCTVTPPPKVAGGLTAAEAPEIIGA
                     PKVLEAPSTTEASGAVAAPGPTVSPMIAQTPGPVVPSPTIVSTGPAAIPWAVAHPGAV
                     QSPGPAVPPMAVQSLVPAAPSWAVVAPPGAVYIPVAAHFAGPAAASRVTQSPGTVIPP
                     LPPPSSVLPRGVPSVPGRTVQSPGAAVHPVAAQSTGVVVPPRAVQYSGAAVTSGGAAV
                     PSGGAATPRAAASTQRTASTEVMQVPRVAAATEATETPRIGTPAMVAEASLPVHSGAA
                     ENPGTSGSSKTAATGKKAAPGAHTGAIPKAGSATGAVPKGGGGKGGNKNRSGGKGKNR
                     KNKVDVDELGMGFRPGDGAAAAAAASANGGQAFLAEIPESEEGESGWTDTESDSDSEP
                     DVPQRGKGKRTIPMHKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNN
                     ANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQGRLQVYMNKV
                     MDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILK
                     ILSNFAENPDMLKKLLGTQVPSSFSSLYNSYVESEILINALTLFEIIFDNLRAEVFNY
                     REFNKGSLFYLCTTSGVCVKKIRALANHHDLLVKVKVIKLVNKF"
     regulatory      3643..3648
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /note="hexamer: AATAAA"
     polyA_site      3668
                     /gene="Armcx2"
                     /gene_synonym="3230401N03Rik; ALEX2"
                     /note="major polyA site"
ORIGIN      
        1 cacaaaggga gaaggggcta cttagggcct cagaggtcac aaagtccctg catgattgac
       61 aggacctgct gtggtgggaa gaggtaggag tagggtaaag gagggggctt gtgctcttgg
      121 tgggagtgga attcggggac ccaagcttac tggtgatgcg ggtcccacgt gaccaagaga
      181 gctgacgtgg gcaaaggtac ttaaagcctt acggccatcc ctgccatctt cctccgggta
      241 ccaacgctat taaagctgcg gtcagtctag cgagacagag aaaattccct cagaactggc
      301 cagacacctt gttgccaaaa ccctgctccc tcccctccct tccctcccct cccctcccag
      361 ccccctgcct ttctagggcg ctagcaaatg ggtgtgccag cttctgtggg agagatggag
      421 catttggagc tgtacgggct tcacaggctg ggggaccgtg agagaatctg gtattagacc
      481 gccatgctaa ctgccaagct gctctccaga cacctgcggc ccaccatccc ttcaccctgg
      541 tccttttggc cctgaaaagg gaattcgggt tcttagtctg cccctgcagt ctgtattcct
      601 gcccttcaac ccgtcctcag caggaaactc tggcctaatt cgaggaagga tacagagctc
      661 tgaattcttg cagacacctt tgtcctggag tgtccttttt ggtgcaggga aggggccgtg
      721 tggaactgtc tttatccgtc taccttgagg ctctgcaact gcgagcacag tggaaattgt
      781 tcctgatccc aggaagctgg tccagctcag cttgcagcct ccgaagaact ttcagacccg
      841 agcttgagat cctcgattgg actggtgtat acatttcgct taagcaagcc agttccacaa
      901 cctggatcag agactcactc caggtgtacc atgagccgag ctcgggatgc tggctgtgta
      961 gctgctggaa tagtgattgg ggcgagtgcc tggtactgtg tctacaaata tactagggga
     1021 aaagaccaga agaagaagag gctgaccaag cccaagaacc gggcctctgt gggtactgga
     1081 agcagggcta gagcgggcct cagagctgga ttcacaattg accttgggcc aggattcagt
     1141 cccccaaacc ccgtcgatat tgagataatg aacaaggccc aaggagaagc ctccaatctt
     1201 gccaccaccg tagctgaaga agtggcacca gctgcaccca gtcctaaggt tcagaatggg
     1261 gcagaaagta aggtccagga gttaaatggg gctaaaactg aggctaatct ggaatcagta
     1321 gtcatgcctt cagctacctg tacagttaca cctcctccca aggtggcagg gggtctcact
     1381 gctgcagagg ctccagaaat cataggagct cccaaagtgc tggaagctcc cagcaccaca
     1441 gaggcttctg gggcagtagc agcccctgga ccaacagtat ctccaatgat agcccagact
     1501 cctgggccag tggtaccttc gccaacaata gtgtctactg ggccagcagc aattccctgg
     1561 gcagtggcac atcccggggc tgtccagtct cctgggccag cagtacctcc catggcagtc
     1621 caatctcttg tgccagcagc accttcctgg gcagtagtag cacctcctgg ggcagtctac
     1681 attcctgtgg cagcccactt tgctgggcca gcagcagctt ccagggtaac ccagtctcct
     1741 gggacggtga tacctcccct tccaccccca tcatcagtac ttcccagggg agtcccatca
     1801 gtacctggca gaacagtcca gtctcctggg gcagccgtgc atcctgtggc agcccaatct
     1861 actggggtag tagtgcctcc tagggcagta cagtattctg gggcagcagt gacttctgga
     1921 ggggcagcag taccttccgg aggggcagca actcctaggg cagcagcatc tacccagagg
     1981 acagcaagca cagaagtcat gcaggtccct agggtggcag cagctactga agccacagag
     2041 actcctagaa taggaacacc tgccatggta gctgaggctt ctctgcccgt gcattctggg
     2101 gctgcagaga atcctgggac ttcagggtcc tctaagacag cagccactgg caagaaagca
     2161 gcccctggag ctcacactgg ggctatacct aaagctgggt cagccactgg agctgtaccc
     2221 aaaggtggag gaggcaaggg tggaaacaag aaccggagtg gaggcaaggg caaaaatagg
     2281 aagaacaagg ttgatgtgga tgagttgggg atgggtttcc gtcctggtga tggggctgca
     2341 gctgcggcgg cggcttctgc taatgggggg caggccttcc tagcagagat tccggaatct
     2401 gaggaagggg aatctgggtg gactgacaca gagtccgatt ctgactctga gccggacgtc
     2461 ccgcagagag ggaaggggaa gagaaccatt cccatgcata agcgcccctt tccatatgaa
     2521 attgatgaga tcctaggtgt tcgagatctc aggaaagtcc tagccttgct tcagaagtca
     2581 gatgatccct tcattcagca agtagccctg ctcaccctga gcaacaatgc caattattca
     2641 tgtaatcaag aaacaatccg aaagttggga ggcctcccaa ttattgcaaa catgatcaac
     2701 aaaactgacc cccacattaa ggaaaaagcc ttaatggcca tgaataacct gagtgaaaat
     2761 tatgaaaacc agggcagact tcaggtgtac atgaataaag tgatggatga tattatggct
     2821 tctaacctga actcagcggt acaggtagtt gggctaaaat ttttaacaaa catgactatt
     2881 actaatgact accagcacct gcttgtcaat tccattgcca actttttccg cttgttatct
     2941 caggggggtg gaaaaatcaa ggttgagatt ctgaaaatac tttcaaactt tgctgaaaat
     3001 ccggacatgc taaagaaact tctcggtacc caggtgccgt catcatttag ttccctttat
     3061 aattcttatg tggaatcaga aattcttatt aatgccctta ctctatttga gattatcttc
     3121 gacaacctca gagcagaagt gttcaactac agggaattca acaaggggtc cctgttttac
     3181 ttatgcacta catctggggt gtgtgtgaag aaaattcgag ccttagcaaa tcaccacgac
     3241 ctcttggtga aagtgaaagt tataaagctg gtaaacaaat tctgattgat ctgtgccctc
     3301 aagatgtgtg atctctcggt tttacactcg ggaagcatta acagtgagac actattgttt
     3361 ttctacttgt gtgtgtagta caggaattat tcagatgcca cgtttgaata attcagagtg
     3421 atgttatctg tgatagtcac cagctttaag ctgaaccatt ttctgaatac caaatagtcc
     3481 cgtagtcctg tagtcctgtg gtttgacttg tgctgcttgg gtgggatatt ttccctgggt
     3541 cctctatgtg aactaatagc aatcctgttc gtgaatggcc tactcagctc ttacttgttt
     3601 tgacttgaat tttgtcacca aagacttcat atgtgtacca tcaataaagt gtatgttgca
     3661 aatggcaaga aaaaaaaaaa aaa
//
