LOCUS       NM_177778               2259 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus armadillo repeat containing 7 (Armc7), transcript
            variant 1, mRNA.
ACCESSION   NM_177778
VERSION     NM_177778.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2259)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2259)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2259)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645470.20.
            
            On Mar 29, 2018 this sequence version replaced NM_177778.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC023126.1, AK146249.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-361               AL645470.20        148797-149157       c
            362-505             AL645470.20        148559-148702       c
            506-2259            AL645470.20        134358-136111       c
FEATURES             Location/Qualifiers
     source          1..2259
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 80.84 cM"
     gene            1..2259
                     /gene="Armc7"
                     /gene_synonym="A630084C13"
                     /note="armadillo repeat containing 7"
                     /db_xref="GeneID:276905"
                     /db_xref="MGI:MGI:2679719"
     exon            1..361
                     /gene="Armc7"
                     /gene_synonym="A630084C13"
                     /inference="alignment:Splign:2.1.0"
     CDS             271..867
                     /gene="Armc7"
                     /gene_synonym="A630084C13"
                     /note="isoform 1 is encoded by transcript variant 1;
                     armadillo repeat-containing protein 7"
                     /codon_start=1
                     /product="armadillo repeat-containing protein 7 isoform 1"
                     /protein_id="NP_808446.1"
                     /db_xref="CCDS:CCDS25636.1"
                     /db_xref="GeneID:276905"
                     /db_xref="MGI:MGI:2679719"
                     /translation="MAQKPKIDPHVGRLGYLQALVTEFQETESQDAKEQVLANLANFA
                     YDPGNYQYLRQLQVLDLFLDSLSEENETLIKFAIGGLCNLCADKANKEHVLQAGGLPL
                     IIGCLSSPDEETVLSAVTTLMYLSSPGSRSHPELTSLPVVQCMLRFSISASTRLRNLA
                     QIFLEDFCSPSQVAEAHSQQAHSALGIPLPKTEAPQQP"
     exon            362..505
                     /gene="Armc7"
                     /gene_synonym="A630084C13"
                     /inference="alignment:Splign:2.1.0"
     exon            506..2259
                     /gene="Armc7"
                     /gene_synonym="A630084C13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1088..1093
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Armc7"
                     /gene_synonym="A630084C13"
                     /note="hexamer: AATAAA"
     polyA_site      1110
                     /gene="Armc7"
                     /gene_synonym="A630084C13"
                     /note="major polyA site"
ORIGIN      
        1 gaaccaggaa gcggtgcagg gagtgtggta agggggcgtg cctgccttca gttccgaaaa
       61 gccacagcgt ctcgcccggg ttgaattttg gttttcagat ccggctcaga caggatcctg
      121 agacccctgg ccacccccac agctcatccc cagctgcaga cgcggatctc aggacaagac
      181 tgggtttgct gccgctctgt cgccgccggg acaggtcagg atccaggcct tgtggcctct
      241 accggagctc ccaactccgc cgccccagcc atggcacaga aacccaagat agacccccac
      301 gtcgggcggc taggctactt gcaggcgctg gtcacagagt tccaggaaac cgagagccaa
      361 gatgccaagg agcaagtcct cgccaacctc gccaacttcg cttatgaccc gggcaactac
      421 cagtacctac ggcaactaca agtcctggac ttattccttg attctctgtc ggaagagaat
      481 gaaaccctaa tcaagtttgc tattgggggg ctctgcaacc tgtgcgcgga caaggccaac
      541 aaggagcacg tcctgcaggc ggggggcctc ccgctcatca tcggctgcct gtccagtcct
      601 gacgaggaga cggtgctgtc tgctgtcacc actctcatgt acctgagctc gccaggctcc
      661 cgctcccatc ccgagctgac ctccctgccc gtggtccagt gcatgctgcg cttctccatc
      721 tctgccagca cacggctccg gaacctggcc cagatattcc tagaggactt ctgctcgccg
      781 agccaggtgg ctgaggccca cagccagcag gcccattctg ccctggggat cccactgcca
      841 aagactgagg ccccacagca gccctgaccc aaggacactt aaagatcctg ccacaggtat
      901 aggaagcaga aggctaatag catcctgagc ccatcctgcg caaagtggtg cttgttcagc
      961 tgcatgcaag ctgcagtctt ggcatgacag gcgtttgcat ccagggaaaa caggaggagg
     1021 gacgaagcca gacttgagat gcttagagga gaaccaaagc tggtatggct ttcatggact
     1081 ggcaatcaat aaactacaga cagaccacca cctctgctgc ccccagtgcc cagctaatgc
     1141 cctcgtgtaa gaagctgtgc ccctgggaga gtggccagta ccatgagtgt ccagagtaat
     1201 tttgatggct agagatcaat cagccttatt gtctggggaa atgccgtggg ttgactcctc
     1261 ccgtgttgag gctgagtatc tgggcatggt agcattgact tggagagctc tgcagaacag
     1321 aaacaactat ccacacagcc ctgctctctg cgaggcgccc taagaggaat gcagaggtga
     1381 agtgtcttcc cttgggtgtc acagcttaat gagtgttaac taaatggcca ttgggcatga
     1441 agaacaaggc cctacaggtg tgagagcaga atgaaggaga actgagggca cccgggcatg
     1501 ccttgtctct ctggagaggc cctacatagg atccttgggt tagacagcaa gacagtgact
     1561 tctgttttac caggctgtgg accactcatg tgccagctgc caagtgtggc atccctgtct
     1621 tttcaaaaga gttgctctgg ccccctttgc ctatgggtca gatcttctga cacttgggtg
     1681 ggagccctga acatgaacct ttcatgggct atcccagtct gcttcctgcc attctctcag
     1741 gagccacaag cctccagtag gtactgtcaa cccctcagga ctcagatgca gaccttccat
     1801 aaagacacct agaaactaat gtcaggggac catggcggcc caacctctaa tctaatccct
     1861 tgagagacag gagcgggata gcgatgagtc tggtccacct agtgagttcc tgaccacaaa
     1921 ggtccgatag agtctaacga gctcctgtaa ctggttaccc cgccctcctc tgccactgag
     1981 aagaaaaaat ggaattaggg gataagcgaa gagcagtcct gacaggaagt ggagtttagg
     2041 gaaaatgggg gccctgatca ctcagcattg tcccccctca gatggacaac gaaagctgag
     2101 gaaggagatc tacaagggct ggagaggggc tgtcgtacag ccactggatg aaggaaggct
     2161 cccgctccca tcctgagctg aaaaggaaaa ggagcatcaa agatccaaag cctcgcgttt
     2221 ggtttttatt tttattaaaa acctcctgat tttctccac
//
