LOCUS       NM_001081083            3004 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus armadillo repeat containing 3 (Armc3), transcript
            variant 1, mRNA.
ACCESSION   NM_001081083 XM_130012
VERSION     NM_001081083.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3004)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3004)
  AUTHORS   Lei,Y., Zhang,X., Xu,Q., Liu,S., Li,C., Jiang,H., Lin,H., Kong,E.,
            Liu,J., Qi,S., Li,H., Xu,W. and Lu,K.
  TITLE     Autophagic elimination of ribosomes during spermiogenesis provides
            energy for flagellar motility
  JOURNAL   Dev Cell 56 (16), 2313-2328 (2021)
   PUBMED   34428398
  REMARK    GeneRIF: Autophagic elimination of ribosomes during spermiogenesis
            provides energy for flagellar motility.
REFERENCE   3  (bases 1 to 3004)
  AUTHORS   Delprato,A., Bonheur,B., Algeo,M.P., Rosay,P., Lu,L., Williams,R.W.
            and Crusio,W.E.
  TITLE     Systems genetic analysis of hippocampal neuroanatomy and spatial
            learning in mice
  JOURNAL   Genes Brain Behav 14 (8), 591-606 (2015)
   PUBMED   26449520
REFERENCE   4  (bases 1 to 3004)
  AUTHORS   Lugani,F., Arora,R., Papeta,N., Patel,A., Zheng,Z., Sterken,R.,
            Singer,R.A., Caridi,G., Mendelsohn,C., Sussel,L., Papaioannou,V.E.
            and Gharavi,A.G.
  TITLE     A retrotransposon insertion in the 5' regulatory domain of Ptf1a
            results in ectopic gene expression and multiple congenital defects
            in Danforth's short tail mouse
  JOURNAL   PLoS Genet 9 (2), e1003206 (2013)
   PUBMED   23437001
REFERENCE   5  (bases 1 to 3004)
  AUTHORS   Vlangos,C.N., Siuniak,A.N., Robinson,D., Chinnaiyan,A.M.,
            Lyons,R.H. Jr., Cavalcoli,J.D. and Keegan,C.E.
  TITLE     Next-generation sequencing identifies the Danforth's short tail
            mouse mutation as a retrotransposon insertion affecting Ptf1a
            expression
  JOURNAL   PLoS Genet 9 (2), e1003205 (2013)
   PUBMED   23437000
REFERENCE   6  (bases 1 to 3004)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: Armc3 is most abundantly expressed in tissues rich in
            highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
REFERENCE   7  (bases 1 to 3004)
  AUTHORS   Lonergan,K.M., Chari,R., Deleeuw,R.J., Shadeo,A., Chi,B.,
            Tsao,M.S., Jones,S., Marra,M., Ling,V., Ng,R., Macaulay,C., Lam,S.
            and Lam,W.L.
  TITLE     Identification of novel lung genes in bronchial epithelium by
            serial analysis of gene expression
  JOURNAL   Am J Respir Cell Mol Biol 35 (6), 651-661 (2006)
   PUBMED   16809635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL929034.17.
            
            On Oct 18, 2012 this sequence version replaced NM_001081083.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014880.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN02415135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-240               AL929034.17        40924-41163
            241-289             AL929034.17        43573-43621
            290-407             AL929034.17        77288-77405
            408-533             AL929034.17        80447-80572
            534-602             AL929034.17        85755-85823
            603-778             AL929034.17        86349-86524
            779-973             AL929034.17        90393-90587
            974-1157            AL929034.17        95662-95845
            1158-1310           AL929034.17        110879-111031
            1311-1416           AL929034.17        111831-111936
            1417-1666           AL929034.17        127693-127942
            1667-1803           AL929034.17        130631-130767
            1804-1972           AL929034.17        134788-134956
            1973-2070           AL929034.17        137195-137292
            2071-2172           AL929034.17        138129-138230
            2173-2268           AL929034.17        138622-138717
            2269-2316           AL929034.17        139712-139759
            2317-2514           AL929034.17        142278-142475
            2515-2677           AL929034.17        145602-145764
            2678-3004           AL929034.17        151723-152049
FEATURES             Location/Qualifiers
     source          1..3004
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 13.2 cM"
     gene            1..3004
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /note="armadillo repeat containing 3"
                     /db_xref="GeneID:70882"
                     /db_xref="MGI:MGI:1918132"
     exon            1..240
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            241..289
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..2887
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     armadillo repeat-containing protein 3"
                     /codon_start=1
                     /product="armadillo repeat-containing protein 3 isoform 1"
                     /protein_id="NP_001074552.1"
                     /db_xref="CCDS:CCDS38052.1"
                     /db_xref="GeneID:70882"
                     /db_xref="MGI:MGI:1918132"
                     /translation="MGKKIKKEVEPPPKDVFDPITIESKKAATVVLMLKSPEEDILAK
                     ACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKTVRRNAMMIFGILASNSDVKK
                     LLRELEVMNSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLS
                     SSDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLRSEYPIIQLLALKTLGVI
                     TCDKEARTMLKENQGLDHLTKILETKELNDLHVEALSVIANCLEDMDTMVLMQQTGSL
                     KKVLSFAESSTIPDIQKNAAKAIAKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKI
                     AASQAISALCENLSCKEFFNTQGIPQIVQLLRSDNEEVREAAALALANLTTSSPANAN
                     AAAEADAIDPLINILSSKRDGAIANAATVLTNMATQEPLRAIIQNHEIMHALLGPLHS
                     TNTLVQSTAALTVAATACDVEARTQLRNCGGLVPLVGLLHSKNDEVRRHASWAVMVCA
                     GDEPMAVELCRLGALNILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSN
                     IISDGFYDYGRINPGTKLLSLKELCLQELNDQRAILLVNNKSDTSPPPSMEDKSSDVG
                     YGRSISSSSSLRRGSKEKANAIFGSPTEEKSEPASVRNTILSRAFTKEKGVSKKKSRL
                     QLICSSYLLWKGKGKKEEEKVKEEEEILALPKFTEGSPEKEWNPPPDPEFCVYVLEVT
                     KSILPIVNLKEQIEVLAKYVADKMGGKIPKEKLADFSWELHISELKFQLKSNVVPIGY
                     IKKGIFYHRALLFKALADKIGVGCSLVRGEYSRGWNEVKLVNEARKGMIGNLPPPEEY
                     IVDLMFHPGNLLKLRSKEADLYRFL"
     exon            290..407
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            408..533
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            534..602
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            603..778
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            779..973
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1157
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1310
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1416
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1666
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1667..1803
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..1972
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1973..2070
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2071..2172
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2268
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2269..2316
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2317..2514
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2515..2677
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2678..3004
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2973..2978
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2995
                     /gene="Armc3"
                     /gene_synonym="4921513G22Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggaggagatt ttgagccttg ttagacttgc catggcacga ttgtggttcc tgcaggattg
       61 attgatcgat cactttggag ctggacaaag ggagccttgg ggctaagaac taattccggg
      121 cagagcacgc atgcgcagcc cagcgtcgcc tagcaacaaa catcaacaca gaccctcaga
      181 ggccagtgga gtttgccaca tgtacagagc cactgcttct tgagacttga ctccgcgcag
      241 gatgggtaaa aagataaaga aggaagttga acctccccct aaggatgtgt ttgacccaat
      301 cacaattgaa agcaaaaagg cagccactgt ggtgctgatg ctcaagtctc cagaggaaga
      361 catcttagcc aaagcctgcg aagccatcta taagtttgct ctgaaaggtg aggagaataa
      421 agcaactctc cttgaacttg gagctgtgga gcctttgacc aaactgctca cccacgaaga
      481 caaaactgta agaagaaatg ctatgatgat ctttggtatt ctggcttcta acagtgatgt
      541 taagaagctc ttgagggagt tagaagttat gaattcagtg attgctcagc tctccccaga
      601 agaagaagtt gtcatccatg agtttgctag tctttgtctt gcgaacatgt ccgtagagta
      661 cacagggaaa gtccagatat ttgagcatgg tggactggag ccgctcatca gactgctgag
      721 cagctcggac ccggacgtga agaagaattc tattgagtgc atctacaact tggtacagga
      781 ttttcagtgt cggactacac ttcaagagct aaatgcaatc cctccgatat tagaactttt
      841 gaggtcagag taccccatta tccagctgct ggctctcaaa accttgggtg tcatcacgtg
      901 cgataaggag gctcggacga tgctgaagga aaatcaaggg ctggaccacc tcaccaagat
      961 cctggagacc aaggaactga atgaccttca tgtagaagca ctctcagtga tagccaactg
     1021 cctggaggat atggacacca tggtgctgat gcagcagaca gggagcctca aaaaagtcct
     1081 gtcattcgca gagagctcca caattcctga cattcagaag aacgcagcca aagctattgc
     1141 caaagcagct tatgaccctg aaaatagaaa agtttttcac gaacaagagg ttgaaaaatg
     1201 cctggtgact ctcctgggat ctgacagcga tggaaccaag attgctgctt cccaggctat
     1261 ttcagccctg tgtgagaact tgagctgcaa agaatttttc aacacccagg ggattccaca
     1321 gatagttcag ttgctcagaa gtgacaatga ggaggtgagg gaagctgccg cactggccct
     1381 ggcaaacctg acgaccagca gccctgcaaa tgccaatgct gctgcagaag cagatgccat
     1441 tgacccgctg attaacatcc tgtcgagcaa gcgggatgga gccattgcca atgctgccac
     1501 agtgctgacc aacatggcca cgcaagagcc tctgcgagct atcatccaga accatgaaat
     1561 aatgcacgca ctgttgggcc ccctgcactc caccaacacc ttggtgcaga gcactgcagc
     1621 gctcaccgtg gctgccactg cctgcgacgt ggaagcccgc acccagttga ggaactgcgg
     1681 tggtctggtg cccctggttg ggctcctgca ctccaagaat gacgaggtac gaaggcatgc
     1741 cagctgggct gtgatggtct gtgccggcga tgagccgatg gcagttgagt tatgcaggct
     1801 cggggcccta aatatccttg aagaaattaa tcgatcatta agtcggaaaa ataaattcag
     1861 tgaggcagcc tataacaaat tgctaaacaa caatctttcc ctgaaataca gccagactgg
     1921 ctatttgtca tcaagcaata taattagcga tggattctat gattacggtc ggataaatcc
     1981 tggcaccaaa cttttgtcac tgaaggaact gtgcttacag gagctgaatg atcaacgtgc
     2041 tattctatta gtcaacaata aatctgacac ctctccacct ccatctatgg aggataaatc
     2101 atcggacgtt ggctatggac gaagcatttc ttcttcatct tccttaagaa ggggaagcaa
     2161 ggagaaggcc aatgctatat ttggatctcc tacagaagaa aaatccgagc cagcatcagt
     2221 acggaacact atccttagca gagctttcac caaagagaag ggagtaagta aaaagaaaag
     2281 tagacttcag ttgatttgtt cctcttacct tctgtggaaa gggaaaggga aaaaagaaga
     2341 agagaaagtg aaagaggaag aagagatcct ggcactgccc aagttcacgg aaggcagccc
     2401 tgagaaagag tggaaccctc ctcctgaccc tgagttctgt gtgtatgtgc tggaggtgac
     2461 caagtcgata ctgcccattg tcaaccttaa ggagcagatt gaggtccttg ccaagtatgt
     2521 ggcagataaa atgggcggta agattccaaa agagaagcta gctgatttca gctgggaact
     2581 tcatataagt gagttgaaat ttcaactgaa atccaatgtc gtaccaattg gatacatcaa
     2641 gaagggaatc ttttatcatc gagcgttgct tttcaaggca ctggctgata aaatcggggt
     2701 aggctgcagc ctggtgcgtg gtgagtacag ccgagggtgg aacgaagtga agctggtgaa
     2761 tgaggctcgg aaaggcatga tcgggaacct gcccccaccc gaagagtaca tcgtggatct
     2821 catgttccac ccggggaacc tgctgaagct gcgcagcaaa gaggctgacc tctaccgctt
     2881 tctgtagtcg ccagaggaac acaagatcac ccaagccaga aattgtcttc gcgtgttttc
     2941 taagaggggc tttagccgat tggataattt caaataaaag tattagaaaa tggtactgtg
     3001 taga
//
