LOCUS       NM_026290               1103 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus armadillo repeat containing 12 (Armc12), mRNA.
ACCESSION   NM_026290
VERSION     NM_026290.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1103)
  AUTHORS   Liu,W., Wei,X., Liu,X., Chen,G., Zhang,X., Liang,X., Isachenko,V.,
            Sha,Y. and Wang,Y.
  TITLE     Biallelic mutations in ARMC12 cause asthenozoospermia and multiple
            midpiece defects in humans and mice
  JOURNAL   J Med Genet 60 (2), 154-162 (2023)
   PUBMED   35534203
  REMARK    GeneRIF: Biallelic mutations in ARMC12 cause asthenozoospermia and
            multiple midpiece defects in humans and mice.
REFERENCE   2  (bases 1 to 1103)
  AUTHORS   Shimada,K., Park,S., Miyata,H., Yu,Z., Morohoshi,A., Oura,S.,
            Matzuk,M.M. and Ikawa,M.
  TITLE     ARMC12 regulates spatiotemporal mitochondrial dynamics during
            spermiogenesis and is required for male fertility
  JOURNAL   Proc Natl Acad Sci U S A 118 (6) (2021)
   PUBMED   33536340
  REMARK    GeneRIF: ARMC12 regulates spatiotemporal mitochondrial dynamics
            during spermiogenesis and is required for male fertility.
REFERENCE   3  (bases 1 to 1103)
  AUTHORS   Li,D., Song,H., Mei,H., Fang,E., Wang,X., Yang,F., Li,H., Chen,Y.,
            Huang,K., Zheng,L. and Tong,Q.
  TITLE     Armadillo repeat containing 12 promotes neuroblastoma progression
            through interaction with retinoblastoma binding protein 4
  JOURNAL   Nat Commun 9 (1), 2829 (2018)
   PUBMED   30026490
  REMARK    GeneRIF: ARMC12 promotes neuroblastoma progression through
            interaction with RBBP4.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154912.3 and AK015756.1.
            
            On Jul 29, 2009 this sequence version replaced NM_026290.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK015756.1, BC049559.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AC154912.3         17347-17363         c
            18-1003             AK015756.1         18-1003
            1004-1103           AC154912.3         9249-9348           c
FEATURES             Location/Qualifiers
     source          1..1103
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 14.74 cM"
     gene            1..1103
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /note="armadillo repeat containing 12"
                     /db_xref="GeneID:67645"
                     /db_xref="MGI:MGI:1914895"
     exon            1..186
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..1046
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /note="testis specific expressed protein 3"
                     /codon_start=1
                     /product="armadillo repeat-containing protein 12"
                     /protein_id="NP_080566.2"
                     /db_xref="CCDS:CCDS28579.1"
                     /db_xref="GeneID:67645"
                     /db_xref="MGI:MGI:1914895"
                     /translation="MGKTIPRFLEQLDLIKSFVGLATGAGALYLLYKAVRTGLKCHPP
                     LCSNSPICIARLAIERERHGRDSGEIRRLLNSLDCKQDEYTRSMILHNITRCVYLLEA
                     EASSCTMDDIDLVADMLDEKDNSVKIQALNALKAFSGIRKFRLKIQEHCIKVLELIST
                     IWDLELHVAGLRLLNNLPLPDYVHPQLRRVMPALMEIIQSDCILAQVQAVRLLSYLAQ
                     KNDLLYDILNCQVRPNFLNLFQSSQPGSLLFEVLVFAEHLSEGRNATHYRAVKWHYNE
                     QSLHEALFGDESRLADRLLSLVIHPEEEVQIQACKVIVSLQCPQDLGSRPSSCRPSHS
                     CFKTGK"
     exon            187..332
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            333..467
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            468..641
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            642..713
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            714..1103
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1061..1066
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1082
                     /gene="Armc12"
                     /gene_synonym="4930511I11Rik"
                     /note="major polyA site"
ORIGIN      
        1 agccacaagg cagcacggaa gacatgggca agaccattcc ccggttcctg gagcaactgg
       61 acctcatcaa aagcttcgtg ggcctggcta caggcgccgg ggccttatac ctgctgtaca
      121 aggccgtcag gactggctta aaatgtcatc cgccactctg ctccaactcg ccgatctgca
      181 ttgcccgcct ggccatcgag agagagcgcc acgggcggga ctccggtgag attcgaagac
      241 ttctcaactc tctagactgc aaacaggatg agtataccag gagcatgatc cttcataaca
      301 tcacccgctg cgtgtacttg ctggaggctg aggcctcttc ttgtactatg gatgacatcg
      361 acttggtggc tgacatgcta gatgagaagg acaacagtgt aaaaatccaa gctctgaatg
      421 cacttaaagc tttctctggc atcaggaaat tcaggctcaa aatccaggag cattgcatca
      481 aggtactgga actgatttcc accatctggg acttggaatt gcacgtagct ggtctccgat
      541 tgctcaacaa cctcccgcta cctgactatg tgcacccaca gctgcggcgg gtgatgcctg
      601 ccctgatgga gatcatacag tcagactgca tcctggcaca ggtacaagct gtccgcctcc
      661 tgagttacct ggcacagaag aacgaccttc tttatgacat tctcaactgt caggtgcgtc
      721 ccaacttcct gaacctcttc cagtcttcac agccgggcag tctgctgttc gaggtgctgg
      781 tgtttgcgga acacttgagt gaaggtcgga acgccaccca ctaccgagcg gtcaaatggc
      841 attacaacga gcaatccctg cacgaagccc tctttgggga tgagtccaga ctggcagacc
      901 gactgctctc cctggtcatc caccctgagg aggaagttca gatccaggcc tgcaaagtca
      961 tagtgagctt gcagtgtccc caggacctgg gatcccgacc ctcttcctgc cgacctagcc
     1021 attcctgctt taaaaccggg aagtgaagtt aaggagatcc aataaatgcg tacgggaggg
     1081 aagctcgagg cctccggaag caa
//
