LOCUS       NM_022989               2553 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus ADP-ribosylation factor-like 6 interacting protein 6
            (Arl6ip6), mRNA.
ACCESSION   NM_022989
VERSION     NM_022989.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2553)
  AUTHORS   Ge,T., Yuan,L., Xu,L., Yang,F., Xu,W., Niu,C., Li,G., Zhou,H. and
            Zheng,Y.
  TITLE     Coiled-coil domain containing 159 is required for spermatid head
            and tail assembly in micedagger
  JOURNAL   Biol Reprod 110 (5), 877-894 (2024)
   PUBMED   38236177
REFERENCE   2  (bases 1 to 2553)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2553)
  AUTHORS   Cheng,L.C., Baboo,S., Lindsay,C., Brusman,L.,
            Martinez-Bartolome,S., Tapia,O., Zhang,X., Yates,J.R. 3rd and
            Gerace,L.
  TITLE     Identification of new transmembrane proteins concentrated at the
            nuclear envelope using organellar proteomics of mesenchymal cells
  JOURNAL   Nucleus 10 (1), 126-143 (2019)
   PUBMED   31142202
REFERENCE   4  (bases 1 to 2553)
  AUTHORS   Miyazaki,H., Yamazaki,M., Watanabe,H., Maehama,T., Yokozeki,T. and
            Kanaho,Y.
  TITLE     The small GTPase ADP-ribosylation factor 6 negatively regulates
            dendritic spine formation
  JOURNAL   FEBS Lett 579 (30), 6834-6838 (2005)
   PUBMED   16325184
  REMARK    GeneRIF: ADP-ribosylation factor 6 negatively regulates dendritic
            spine formation.
REFERENCE   5  (bases 1 to 2553)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 2553)
  AUTHORS   Ingley,E., Williams,J.H., Walker,C.E., Tsai,S., Colley,S.,
            Sayer,M.S., Tilbrook,P.A., Sarna,M., Beaumont,J.G. and Klinken,S.P.
  TITLE     A novel ADP-ribosylation like factor (ARL-6), interacts with the
            protein-conducting channel SEC61beta subunit
  JOURNAL   FEBS Lett 459 (1), 69-74 (1999)
   PUBMED   10508919
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845170.5, AK082824.1 and AL844552.4.
            
            On Jul 18, 2009 this sequence version replaced NM_022989.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK159990.1, AK032740.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                AL845170.5         177108-177136
            30-1776             AK082824.1         2-1748
            1777-2553           AL844552.4         21484-22260
FEATURES             Location/Qualifiers
     source          1..2553
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 30.69 cM"
     gene            1..2553
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /note="ADP-ribosylation factor-like 6 interacting protein
                     6"
                     /db_xref="GeneID:65103"
                     /db_xref="MGI:MGI:1929507"
     exon            1..439
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..720
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /note="ADP-ribosylation-like factor 6 interacting protein
                     6; ARL-6-interacting protein 6"
                     /codon_start=1
                     /product="ADP-ribosylation factor-like protein
                     6-interacting protein 6"
                     /protein_id="NP_075365.3"
                     /db_xref="CCDS:CCDS16039.1"
                     /db_xref="GeneID:65103"
                     /db_xref="MGI:MGI:1929507"
                     /translation="MSFVESWRFAGARRRRQVTPGPATRPGYSDYTQGDSWGEGEGDE
                     DEGCDQVARDLRAEFSARASSETKRAPLLPRVGDGSPVLPDKRNGIFPATAAKRTQAR
                     RWPIQALSILCSLLFAVLLAFLLAIAYMIVKELHAENLKNEDDIHTGLLGFWSLLIIS
                     LTAGLSCCSFSWTVTYFDSFEPGMFPPTPLSPARFKKLTGHSFHMGYSMAILNGIVAA
                     LTVAWCLM"
     exon            440..493
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /inference="alignment:Splign:2.1.0"
     exon            494..626
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /inference="alignment:Splign:2.1.0"
     exon            627..2553
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1751..1756
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /note="hexamer: AATATA"
     polyA_site      1779
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /note="major polyA site"
     polyA_site      1818
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /note="major polyA site"
     regulatory      2531..2536
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /note="hexamer: ATTAAA"
     polyA_site      2549
                     /gene="Arl6ip6"
                     /gene_synonym="2310057C01Rik; 2610529A11Rik; Aip-6"
                     /note="major polyA site"
ORIGIN      
        1 ggacagccga ccttcgcggg actctcagtc tttcccgcca tgtcgttcgt ggagagttgg
       61 aggtttgcgg gcgcgcggag gcgccgtcag gttaccccag gccctgcgac tcggcccggg
      121 tattccgact acactcaggg ggacagctgg ggtgagggcg aaggcgacga agacgaggga
      181 tgcgaccaag tggcccgcga cttgcgggca gagttctcag ccagggcgtc gtcggagacc
      241 aagagggccc cgctactccc ccgggtcggg gacgggtctc cggtcctgcc ggataagcgc
      301 aacggcatct tcccggccac tgcggccaag cgaacccagg ctcggcggtg gcccatccaa
      361 gccctttcca ttctctgttc gctgctgttc gccgtcctcc ttgctttcct tctcgccatc
      421 gcctacatga tcgttaaaga attgcatgca gaaaacttga aaaatgaaga tgatatacat
      481 actgggctgt taggcttctg gtctctgctg ataatatctc taactgctgg attgtcctgt
      541 tgcagctttt cttggacagt gacttacttt gattcatttg aaccaggaat gtttccaccc
      601 actcctcttt cacctgctag gttcaagaaa ctgactggac attctttcca catgggctac
      661 agcatggcaa ttttgaatgg tattgtcgct gctctcactg tggcatggtg cctcatgtaa
      721 acctacacta gagcaacgtt gttggtgaaa gtcatgatgg tttttgaagt agcagaaacg
      781 aaattgctga ctcagaagac tttgaaatgt gatcagatac ttactatcat cattatggaa
      841 gaccttatag agggcacttc ttcaatgtat aagatgttta cttcatcttt ttacttttgt
      901 ttatgtagtt tatcagttac agaaaatatt tgaattgaaa tcaaacttgg aaacttgaat
      961 acatgacatt gcctaccttt ctatgtatat tccatttttt actaacagat actgatattt
     1021 gtggttgagg tagaaatatt tatatactat attaggaaaa cagtactgag gccaagtgtg
     1081 ttagcaagac cttcaagccc agcattttgg agacagaagc aggttctgtg ggtttgaggc
     1141 tagcctgtag ctgcacaatg agatcatttc ataaaaaaga aaacaattcc tattctttga
     1201 cattttgtag aagctacata aatcagagtt tttgataatc agtagaatgc atatgtgcat
     1261 ttatattttt gtggagtgta cctgggtgtc ttatagattt ttataatact gcatttgtgt
     1321 tttaaatgat tacatttata cctatatggc tgtaaatttt atttcttagc tggtgtagac
     1381 ctgtccttta gtattttgtc tcttcaaaaa gaattaaagt acattgactt gagtttaaga
     1441 ttaagtaaat atatttttta acaaaaacat actacaaatt cagggtaaac tatttgttgt
     1501 tataatgtta agaaatttga gacttttagc catttctatt ttctacaatt gaaagtattt
     1561 attttgatgt atatattagg gtagcaaact tgtactattt catttttagt aaatgaaaac
     1621 ctaaaaattt tgtatgtaga aatgtttgaa cttgtttatt tttaatctcg agtatttagt
     1681 tgccaaagta gaaaaggtat tttgatactc tgtatgtgta catataattt aactgtaata
     1741 tgtatgttgt aatatattat agatactgta cttgtcatat caagggttct tgttgttatt
     1801 aattaagctt taaatgtttc tctgtcttgc ttgctattta agtatgtaga aagtcacctc
     1861 aatcttagaa agttgtgtgg tttacacagc tgtttgtcct ggctgtagga aaatttagat
     1921 taggaaaaca ttgtgtagtc agtgtgtatt ctagctaagt ggcaagtgag tgtgtgtgtg
     1981 tgtgtgtgtg tgtgtgtgtt acatctgcag tcctactgtt gttactacac aagggttcta
     2041 aaagtctcaa cattttctct atattctcca aaaaaggtca tttccattta attggaaatg
     2101 gctaataatg ttccaattaa agtgagtgat gaagagggac atagatagat agattcttac
     2161 taaatgccag tctcatgact taatagccct actaattatg ctttttaaaa tgattgttct
     2221 tgttgtttat tggatttttc atacaatata ttttgacttt attcttttta cacgattccc
     2281 tacccccaac tctttctata tcatctcctt tccctccacc tcccacccat ccaacttcat
     2341 gttctatctt tcagggggaa aaagaaatct gtgtatttga attagtgttt tttttttaat
     2401 tctcaggcat cttacattct ttcttctacc tttcccttaa aggactcttt attacaaaga
     2461 tatgttcaaa ttataaaatt attttatctc ctctctacct gtgtaaagcc ccattcccat
     2521 tatcacccca attaaaatgg ctccttccac ttc
//
