LOCUS       NP_062292                203 aa            linear   ROD 30-APR-2024
DEFINITION  ADP-ribosylation factor-like protein 6-interacting protein 1 [Mus
            musculus].
ACCESSION   NP_062292 XP_133792
VERSION     NP_062292.1
DBSOURCE    REFSEQ: accession NM_019419.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 203)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 203)
  AUTHORS   Lim,J.H., Kang,H.M., Kim,D.H., Jeong,B., Lee,D.Y., Lee,J.R.,
            Baek,J.Y., Cho,H.S., Son,M.Y., Kim,D.S., Kim,N.S. and Jung,C.R.
  TITLE     ARL6IP1 gene delivery reduces neuroinflammation and
            neurodegenerative pathology in hereditary spastic paraplegia model
  JOURNAL   J Exp Med 221 (1) (2024)
   PUBMED   37934410
  REMARK    GeneRIF: ARL6IP1 gene delivery reduces neuroinflammation and
            neurodegenerative pathology in hereditary spastic paraplegia model.
REFERENCE   3  (residues 1 to 203)
  AUTHORS   Foronda,H., Fu,Y., Covarrubias-Pinto,A., Bocker,H.T., Gonzalez,A.,
            Seemann,E., Franzka,P., Bock,A., Bhaskara,R.M., Liebmann,L.,
            Hoffmann,M.E., Katona,I., Koch,N., Weis,J., Kurth,I., Gleeson,J.G.,
            Reggiori,F., Hummer,G., Kessels,M.M., Qualmann,B., Mari,M.,
            Dikic,I. and Hubner,C.A.
  TITLE     Heteromeric clusters of ubiquitinated ER-shaping proteins drive
            ER-phagy
  JOURNAL   Nature 618 (7964), 402-410 (2023)
   PUBMED   37225994
REFERENCE   4  (residues 1 to 203)
  AUTHORS   Zhou,G.F., Tang,J., Ma,Y.L., Fu,X., Liu,J.Y., Yang,R.Z.,
            Zhang,H.S., Cai,X.H., Wang,J.W., Xie,X.Y., Song,L., Luo,B.,
            Chen,J., Chen,L., Deng,X.J. and Chen,G.J.
  TITLE     ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer
            pathology through FXR1-dependent BACE1 translation initiation
  JOURNAL   Proc Natl Acad Sci U S A 120 (22), e2220148120 (2023)
   PUBMED   37216506
  REMARK    GeneRIF: ARL6IP1 mediates small-molecule-induced alleviation of
            Alzheimer pathology through FXR1-dependent BACE1 translation
            initiation.
REFERENCE   5  (residues 1 to 203)
  AUTHORS   Pinson,M.R., Chung,D.D., Mahnke,A.H., Salem,N.A., Osorio,D.,
            Nair,V., Payne,E.A., Del Real,J.J., Cai,J.J. and Miranda,R.C.
  TITLE     Gag-like proteins: Novel mediators of prenatal alcohol exposure in
            neural development
  JOURNAL   Alcohol Clin Exp Res 46 (4), 556-569 (2022)
   PUBMED   35187673
REFERENCE   6  (residues 1 to 203)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   7  (residues 1 to 203)
  AUTHORS   Lui,H.M., Chen,J., Wang,L. and Naumovski,L.
  TITLE     ARMER, apoptotic regulator in the membrane of the endoplasmic
            reticulum, a novel inhibitor of apoptosis
  JOURNAL   Mol Cancer Res 1 (7), 508-518 (2003)
   PUBMED   12754298
REFERENCE   8  (residues 1 to 203)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (residues 1 to 203)
  AUTHORS   Pettersson,M., Bessonova,M., Gu,H.F., Groop,L.C. and Jonsson,J.I.
  TITLE     Characterization, chromosomal localization, and expression during
            hematopoietic differentiation of the gene encoding Arl6ip,
            ADP-ribosylation-like factor-6 interacting protein (ARL6)
  JOURNAL   Genomics 68 (3), 351-354 (2000)
   PUBMED   10995579
REFERENCE   10 (residues 1 to 203)
  AUTHORS   Ingley,E., Williams,J.H., Walker,C.E., Tsai,S., Colley,S.,
            Sayer,M.S., Tilbrook,P.A., Sarna,M., Beaumont,J.G. and Klinken,S.P.
  TITLE     A novel ADP-ribosylation like factor (ARL-6), interacts with the
            protein-conducting channel SEC61beta subunit
  JOURNAL   FEBS Lett 459 (1), 69-74 (1999)
   PUBMED   10508919
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131788.3, AK152565.1 and BC046792.1.
            
            On Mar 22, 2004 this sequence version replaced XP_133792.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC046792.1, AF172088.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..203
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 63.44 cM"
     Protein         1..203
                     /product="ADP-ribosylation factor-like protein
                     6-interacting protein 1"
                     /note="ARL-6-interacting protein 1; ADP-ribosylation-like
                     factor 6 interacting protein"
                     /calculated_mol_wt=23306
     Region          34..200
                     /region_name="Arl6IP1"
                     /note="ADP-ribosylation factor-like protein 6-interacting
                     protein 1; cd22559"
                     /db_xref="CDD:411698"
     Site            42..62
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9JKW0.1)"
     Site            66..86
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9JKW0.1)"
     Site            134..175
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9JKW0.1)"
     CDS             1..203
                     /gene="Arl6ip1"
                     /gene_synonym="Aip-1; AIP-6; Arl6ip; ARMER; mKIAA0069"
                     /coded_by="NM_019419.2:122..733"
                     /db_xref="CCDS:CCDS21769.1"
                     /db_xref="GeneID:54208"
                     /db_xref="MGI:MGI:1858943"
ORIGIN      
        1 maegdnrssn llavetasle eqlqgwgevm lmadkvlrwe rawfppaimg vvsllfliiy
       61 yldpsvlsgv scfvmflcla dylvpilapr ifgsnkwtte qqqrfheics nlvktrrrav
      121 gwwkrlfslk eekpkmyfmt miislaavaw vgqqvhnlll tylivtfvll lpglnqhgii
      181 lkyigmakre inkllkqkek kne
//
