LOCUS       NM_207231               1616 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus ADP-ribosylation factor-like 5C (Arl5c), transcript
            variant 1, mRNA.
ACCESSION   NM_207231 XM_147612
VERSION     NM_207231.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1616)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1616)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 1616)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC065791.1.
            
            On Aug 30, 2004 this sequence version replaced XM_147612.3.
            
            Transcript Variant: This variant (1) represents the protein-coding
            transcript.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC065791.1, SRR5189673.79386.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1616
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 61.47 cM"
     gene            1..1616
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /note="ADP-ribosylation factor-like 5C"
                     /db_xref="GeneID:217151"
                     /db_xref="MGI:MGI:3028577"
     exon            1..356
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /inference="alignment:Splign:2.1.0"
     CDS             311..850
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /note="ADP-ribosylation factor-like 12; ADP-ribosylation
                     factor-like 5C protein; ADP-ribosylation factor-like
                     protein 12"
                     /codon_start=1
                     /product="ADP-ribosylation factor-like protein 5C"
                     /protein_id="NP_997114.1"
                     /db_xref="CCDS:CCDS25334.1"
                     /db_xref="GeneID:217151"
                     /db_xref="MGI:MGI:3028577"
                     /translation="MGQLIAKLMRIFGSQEHKVIIVGLDNAGKTTILYQFLTNEVVHT
                     CSTIGSNVEEIVLRKTHFLMWDLGGQEALRSTWDTYYSNAEFVILVIDSTDRNRLLTT
                     REELYKMLAHEALQNASVLIFANKQDVKDSMTTAEISQFLTLSAIKDHPWHIQGCCAL
                     TGEGLPAGLQWMQAQATAN"
     exon            357..417
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /inference="alignment:Splign:2.1.0"
     exon            418..565
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /inference="alignment:Splign:2.1.0"
     exon            566..649
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /inference="alignment:Splign:2.1.0"
     exon            650..801
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /inference="alignment:Splign:2.1.0"
     exon            802..1563
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1533..1538
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /note="hexamer: ATTAAA"
     regulatory      1546..1551
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /note="hexamer: AATAAG"
     polyA_site      1558
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /note="major polyA site"
     polyA_site      1563
                     /gene="Arl5c"
                     /gene_synonym="Arl12"
                     /note="major polyA site"
ORIGIN      
        1 ctcgcaacac taaagcagat agttccaact tcagttttct cagggtaaag aggactctgg
       61 gattttcctt gcactttcct gcccctagac aaatacctag tcttcgtggt gacgccactc
      121 agaccctcag caccgagaaa gagccagcgt ccggtgggat tcccaggtct cgagggtgac
      181 gcttggggtt ccgcacattt gataggagca gcgggtctgg ccctccccca ggcagggctt
      241 tgaagatttg gggccagact ctggtcctgg aggctgctga gccccgcccg cccccagctc
      301 cgggagtgcc atgggacagc tgatagccaa gctgatgcga atctttggga gtcaggagca
      361 caaagtcatt atcgtgggac tggacaatgc agggaagacc accattctct accagttcct
      421 gaccaatgag gttgttcaca cctgctccac cattgggagc aacgtggaag aaattgttct
      481 tcggaagact cacttcctca tgtgggacct agggggccag gaggcgctgc gctccacctg
      541 ggacacttac tactctaatg ctgagtttgt catccttgtg atagatagca cagaccggaa
      601 tcggctgctc accacccggg aggagctgta taagatgctg gcccatgagg cacttcaaaa
      661 tgcttcagta ctgatctttg ccaacaagca ggatgtgaaa gactccatga ccacagcaga
      721 gatctcccaa tttctcacac tcagtgccat caaagaccac ccgtggcata tccagggctg
      781 ctgtgctctc acaggagaag ggctgccagc tgggctccag tggatgcaag ctcaggccac
      841 cgccaactga tgtcctagcc cgaggccaac cagaaaccaa atgactagca ccagtgagaa
      901 acaccagtca tttgttggtg gaaagagggt ggctatggac aaaaagatta ctacagtcct
      961 ctcagctgtc actgagagct ggatcaaaga cttcaagttg gtgcagacag gactacagat
     1021 gaagctgtcc acccactcca tcactgctgg tgtgaagaga gacactaggg aacttactgc
     1081 ggagtgttgg gggcaccagg tctcccagtc ctcacgttct gtcttctcgg caagcaagag
     1141 atctttgaca tttcccccta tccactggac gaaggagatt ccgataaagg aggcaatagg
     1201 acccggtcaa aagctggggg gcatgagggt gggggtggga ggcagagagt tgatgaatga
     1261 gaggacagaa cattccagac tgtcgcagtc ccttacactg cagggttcta agcccctcca
     1321 ccaccaaccg ctcgctttcc tgctcactgt tccctcttag gtgctaactt caggaccaca
     1381 gtttttggga cctaagtcac cacgtggaat ctccttctct cttagcatcc ctctggtatg
     1441 aatcccactc ctctgaaatg tcaaggatct ataggaccta cttattttgt ctttgtgtca
     1501 tgattttttt aacatcgcat tatgatttta aaattaaaga tacacaataa gtgtccctga
     1561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
