LOCUS       NM_019718                919 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript
            variant 1, mRNA.
ACCESSION   NM_019718
VERSION     NM_019718.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Ma,X., Zhang,Y., Zhang,Y., Zhang,X., Huang,Y., He,K., Chen,C.,
            Hao,J., Zhao,D., LeBrasseur,N.K., Kirkland,J.L., Chini,E.N.,
            Wei,Q., Ling,K. and Hu,J.
  TITLE     A stress-induced cilium-to-PML-NB route drives senescence
            initiation
  JOURNAL   Nat Commun 14 (1), 1840 (2023)
   PUBMED   37019904
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 919)
  AUTHORS   Travis,A.M., Manocha,S., Willer,J.R., Wessler,T.S., Skiba,N.P. and
            Pearring,J.N.
  TITLE     Disrupting the ciliary gradient of active Arl3 affects rod
            photoreceptor nuclear migration
  JOURNAL   Elife 12, e80533 (2023)
   PUBMED   36598133
  REMARK    GeneRIF: Disrupting the ciliary gradient of active Arl3 affects rod
            photoreceptor nuclear migration.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 919)
  AUTHORS   Li,W., Zhu,Z., He,K., Ma,X., Pignolo,R.J., Sieck,G.C., Hu,J. and
            Wang,H.
  TITLE     Primary cilia in satellite cells are the mechanical sensors for
            muscle hypertrophy
  JOURNAL   Proc Natl Acad Sci U S A 119 (24), e2103615119 (2022)
   PUBMED   35671424
REFERENCE   4  (bases 1 to 919)
  AUTHORS   Collin,G.B., Gogna,N., Chang,B., Damkham,N., Pinkney,J., Hyde,L.F.,
            Stone,L., Naggert,J.K., Nishina,P.M. and Krebs,M.P.
  TITLE     Mouse Models of Inherited Retinal Degeneration with Photoreceptor
            Cell Loss
  JOURNAL   Cells 9 (4), 931 (2020)
   PUBMED   32290105
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 919)
  AUTHORS   Bhattarai,S.R., Begum,S., Popow,R. and Ezratty,E.J.
  TITLE     The ciliary GTPase Arl3 maintains tissue architecture by directing
            planar spindle orientation during epidermal morphogenesis
  JOURNAL   Development 146 (9) (2019)
   PUBMED   30952667
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 919)
  AUTHORS   Osipovich,A.B., Singh,A. and Ruley,H.E.
  TITLE     Post-entrapment genome engineering: first exon size does not affect
            the expression of fusion transcripts generated by gene entrapment
  JOURNAL   Genome Res 15 (3), 428-435 (2005)
   PUBMED   15741512
REFERENCE   7  (bases 1 to 919)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   8  (bases 1 to 919)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 919)
  AUTHORS   Hanzal-Bayer,M., Renault,L., Roversi,P., Wittinghofer,A. and
            Hillig,R.C.
  TITLE     The complex of Arl2-GTP and PDE delta: from structure to function
  JOURNAL   EMBO J 21 (9), 2095-2106 (2002)
   PUBMED   11980706
REFERENCE   10 (bases 1 to 919)
  AUTHORS   Linari,M., Hanzal-Bayer,M. and Becker,J.
  TITLE     The delta subunit of rod specific cyclic GMP phosphodiesterase, PDE
            delta, interacts with the Arf-like protein Arl3 in a GTP specific
            manner
  JOURNAL   FEBS Lett 458 (1), 55-59 (1999)
   PUBMED   10518933
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156982.8.
            
            On Sep 13, 2017 this sequence version replaced NM_019718.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC042941.1, CX565420.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AC156982.8         116781-116923       c
            144-287             AC156982.8         101979-102122       c
            288-404             AC156982.8         95314-95430         c
            405-455             AC156982.8         87223-87273         c
            456-641             AC156982.8         86093-86278         c
            642-919             AC156982.8         74850-75127         c
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 38.94 cM"
     gene            1..919
                     /gene="Arl3"
                     /note="ADP-ribosylation factor-like 3"
                     /db_xref="GeneID:56350"
                     /db_xref="MGI:MGI:1929699"
     exon            1..143
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..689
                     /gene="Arl3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ADP-ribosylation factor-like protein 3;
                     ADP-ribosylation-like 3"
                     /codon_start=1
                     /product="ADP-ribosylation factor-like protein 3 isoform
                     1"
                     /protein_id="NP_062692.1"
                     /db_xref="CCDS:CCDS38010.1"
                     /db_xref="GeneID:56350"
                     /db_xref="MGI:MGI:1929699"
                     /translation="MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISH
                     ITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFEE
                     TGQELTELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSA
                     LTGEGVQDGMNWVCKNVNAKKK"
     exon            144..287
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     exon            288..404
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     exon            405..455
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     exon            456..641
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     exon            642..919
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      893..898
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arl3"
                     /note="hexamer: AATAAA"
     polyA_site      919
                     /gene="Arl3"
                     /note="major polyA site"
ORIGIN      
        1 gaaccccgcc ccatcccgct gctccgttcc tccgctgtgc gtgcgaggga cgtcaggggc
       61 ggcgccgcag cagttacccc tggtaacggg ggaggcagga ggaggaggcg gaggaggagg
      121 aggagggact cggcttgagg atgggcttgc tctctatttt gcgcaaattg aaaagtgcac
      181 cagaccagga ggtgcgaatc ctactcctgg gcttggacaa cgcgggcaag actaccttgc
      241 tgaagcaact cgcatctgaa gacatcagcc acatcacacc tacacaggga tttaacatca
      301 aaagcgtgca gtcacaaggt tttaagctga atgtatggga cattggcggg cagaggaaaa
      361 tcagaccata ctggagaagt tattttgaaa atactgatat tctcatctat gtaattgaca
      421 gtgccgacag aaagagattt gaagagacgg gtcaggaact aacggaatta ctggaggaag
      481 aaaagctgag ttgtgtgccc gtgctcatct ttgctaacaa gcaggacctg ctcacggcag
      541 ccccagcctc cgagatcgca gaagggctaa acctccacac catccgggac cgcgtctggc
      601 agatccagtc ctgttcagcg ctcacaggcg agggcgtcca ggatggcatg aactgggtct
      661 gcaagaatgt caacgcaaag aagaaataaa acggaggcag gcggatggtg gcgctggagc
      721 cgggagctag agtcagccct agaaacactg ggttgctgct ttctgaccaa atgcttttct
      781 gtctgtgcac agccacagct gtgtggcggg cggggaggga cagcagcctg agaaagatcc
      841 ccatcccagc agtagatttt aactgatctc agaggctcgg tatcgttttt caaataaagg
      901 aattatatta tttcctctg
//
