LOCUS       NM_019722                869 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus ADP-ribosylation factor-like 2 (Arl2), mRNA.
ACCESSION   NM_019722
VERSION     NM_019722.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 869)
  AUTHORS   Ma,D., Lin,K.Y., Suresh,D., Lin,J., Gujar,M.R., Aung,H.Y.,
            Tan,Y.S., Gao,Y., Vincent,A.S., Chen,T. and Wang,H.
  TITLE     Arl2 GTPase associates with the centrosomal protein Cdk5rap2 to
            regulate cortical development via microtubule organization
  JOURNAL   PLoS Biol 22 (8), e3002751 (2024)
   PUBMED   39137170
  REMARK    GeneRIF: Arl2 GTPase associates with the centrosomal protein
            Cdk5rap2 to regulate cortical development via microtubule
            organization.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 869)
  AUTHORS   Tang,Y., Zhou,L. and Liu,L.
  TITLE     Circ_0085616 contributes to the radio-resistance and progression of
            cervical cancer by targeting miR-541-3p/ARL2 signaling
  JOURNAL   Histol Histopathol 38 (5), 571-584 (2023)
   PUBMED   36300495
  REMARK    GeneRIF: Circ_0085616 contributes to the radio-resistance and
            progression of cervical cancer by targeting miR-541-3p/ARL2
            signaling.
REFERENCE   3  (bases 1 to 869)
  AUTHORS   Gerstner,C.D., Reed,M., Dahl,T.M., Ying,G., Frederick,J.M. and
            Baehr,W.
  TITLE     Arf-like Protein 2 (ARL2) Controls Microtubule Neogenesis during
            Early Postnatal Photoreceptor Development
  JOURNAL   Cells 12 (1), 147 (2022)
   PUBMED   36611941
  REMARK    GeneRIF: Arf-like Protein 2 (ARL2) Controls Microtubule Neogenesis
            during Early Postnatal Photoreceptor Development.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 869)
  AUTHORS   Yan,B., Liu,T., Yao,C., Liu,X., Du,Q. and Pan,L.
  TITLE     LncRNA XIST shuttled by adipose tissue-derived mesenchymal stem
            cell-derived extracellular vesicles suppresses myocardial
            pyroptosis in atrial fibrillation by disrupting miR-214-3p-mediated
            Arl2 inhibition
  JOURNAL   Lab Invest 101 (11), 1427-1438 (2021)
   PUBMED   34389797
  REMARK    GeneRIF: LncRNA XIST shuttled by adipose tissue-derived mesenchymal
            stem cell-derived extracellular vesicles suppresses myocardial
            pyroptosis in atrial fibrillation by disrupting miR-214-3p-mediated
            Arl2 inhibition.
REFERENCE   5  (bases 1 to 869)
  AUTHORS   Dewhurst,M.R., Ow,J.R., Zafer,G., van Hul,N.K.M., Wollmann,H.,
            Bisteau,X., Brough,D., Choi,H. and Kaldis,P.
  TITLE     Loss of hepatocyte cell division leads to liver inflammation and
            fibrosis
  JOURNAL   PLoS Genet 16 (11), e1009084 (2020)
   PUBMED   33147210
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 869)
  AUTHORS   Muromoto,R., Sekine,Y., Imoto,S., Ikeda,O., Okayama,T., Sato,N. and
            Matsuda,T.
  TITLE     BART is essential for nuclear retention of STAT3
  JOURNAL   Int Immunol 20 (3), 395-403 (2008)
   PUBMED   18234692
REFERENCE   7  (bases 1 to 869)
  AUTHORS   Zhou,C., Cunningham,L., Marcus,A.I., Li,Y. and Kahn,R.A.
  TITLE     Arl2 and Arl3 regulate different microtubule-dependent processes
  JOURNAL   Mol Biol Cell 17 (5), 2476-2487 (2006)
   PUBMED   16525022
REFERENCE   8  (bases 1 to 869)
  AUTHORS   Hanzal-Bayer,M., Linari,M. and Wittinghofer,A.
  TITLE     Properties of the interaction of Arf-like protein 2 with PDEdelta
  JOURNAL   J Mol Biol 350 (5), 1074-1082 (2005)
   PUBMED   15979089
  REMARK    GeneRIF: Arf-like protein 2 interaction with PDEdelta is dependent
            on GTP, and the binding of PDEdelta substantially stabilizes GTP
            binding; data suggests that Arl2/3 are specific regulators of
            PDEdelta
REFERENCE   9  (bases 1 to 869)
  AUTHORS   Hanzal-Bayer,M., Renault,L., Roversi,P., Wittinghofer,A. and
            Hillig,R.C.
  TITLE     The complex of Arl2-GTP and PDE delta: from structure to function
  JOURNAL   EMBO J 21 (9), 2095-2106 (2002)
   PUBMED   11980706
REFERENCE   10 (bases 1 to 869)
  AUTHORS   Sharer,J.D., Shern,J.F., Van Valkenburgh,H., Wallace,D.C. and
            Kahn,R.A.
  TITLE     ARL2 and BART enter mitochondria and bind the adenine nucleotide
            transporter
  JOURNAL   Mol Biol Cell 13 (1), 71-83 (2002)
   PUBMED   11809823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK011366.1.
            
            On Jun 20, 2003 this sequence version replaced NM_019722.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011366.1, BC060259.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.34 cM"
     gene            1..869
                     /gene="Arl2"
                     /gene_synonym="2610009M23Rik"
                     /note="ADP-ribosylation factor-like 2"
                     /db_xref="GeneID:56327"
                     /db_xref="MGI:MGI:1928393"
     exon            1..101
                     /gene="Arl2"
                     /gene_synonym="2610009M23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..591
                     /gene="Arl2"
                     /gene_synonym="2610009M23Rik"
                     /note="arf-like protein 2; ADP-ribosylation-like 2"
                     /codon_start=1
                     /product="ADP-ribosylation factor-like protein 2"
                     /protein_id="NP_062696.2"
                     /db_xref="CCDS:CCDS29496.1"
                     /db_xref="GeneID:56327"
                     /db_xref="MGI:MGI:1928393"
                     /translation="MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDVDTI
                     SPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDC
                     QRELQSLLVEERLAGATLLIFANKQDLPGALSCNAIQEALELDSIRSHHWRIQGCSAV
                     TGEDLLPGIDWLLDDISSRVFTAD"
     exon            102..212
                     /gene="Arl2"
                     /gene_synonym="2610009M23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            213..375
                     /gene="Arl2"
                     /gene_synonym="2610009M23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            376..456
                     /gene="Arl2"
                     /gene_synonym="2610009M23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            457..869
                     /gene="Arl2"
                     /gene_synonym="2610009M23Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      869
                     /gene="Arl2"
                     /gene_synonym="2610009M23Rik"
                     /note="putative"
ORIGIN      
        1 tagaagaaac ggcggccggg agggggctac gggatcatgg ggcttctgac cattctgaag
       61 aagatgaagc agaaagagcg agagctgcgg ctgctcatgc ttggcttgga caacgctggc
      121 aaaacaacca tcctcaagaa gttcaatgga gaagacgtgg acaccatctc cccgacactg
      181 ggcttcaaca tcaagaccct ggagcaccgc ggattcaagc tgaacatctg ggatgtaggt
      241 ggccagaagt ctctgcgctc ctactggagg aactactttg agagcacgga tggcctcatc
      301 tgggtggtgg acagcgccga ccgccagcgc atgcaggact gtcagcgaga gctgcagagc
      361 ctactggtgg aggagcgcct ggctggagca accctcctca tctttgccaa caagcaggac
      421 ctgcctggag cactgtcctg taatgctatt caggaggccc tggagctgga ctccatccgc
      481 agccaccact ggcgcatcca gggctgcagt gctgtcacag gggaagacct gctgcctggc
      541 atcgactggc tccttgatga catttccagt cgtgtcttta ctgccgactg agcttcttca
      601 gtgtccccag gtccctgtcc tcatcagaca ccagccagag ggatgagcac cagctggcca
      661 gactaacact cccaacccca ccatgacctg ctgctgctat tactgcccat tgctgctccc
      721 ccgggtgagg gctgtcaccc tgtctcccaa agtggcctgc agctgccatg ccaaaaggaa
      781 aggctgggct gggagggact acctgctgct gccagggtcc taggtgtcgc ctcgcctcgg
      841 tccagcagtg agaataaagc actcttcac
//
