LOCUS       NM_023598               4494 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus AT-rich interaction domain 5B (Arid5b), mRNA.
ACCESSION   NM_023598 XM_907858 XM_920585 XM_920592 XM_920598
VERSION     NM_023598.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4494)
  AUTHORS   Chalise,J.P., Ehsani,A., Lemecha,M., Hung,Y.W., Zhang,G.,
            Larson,G.P. and Itakura,K.
  TITLE     ARID5B regulates fatty acid metabolism and proliferation at the
            Pre-B cell stage during B cell development
  JOURNAL   Front Immunol 14, 1170475 (2023)
   PUBMED   37483604
  REMARK    GeneRIF: ARID5B regulates fatty acid metabolism and proliferation
            at the Pre-B cell stage during B cell development.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4494)
  AUTHORS   Goodings,C., Zhao,X., McKinney-Freeman,S., Zhang,H. and Yang,J.J.
  TITLE     ARID5B influences B-cell development and function in mouse
  JOURNAL   Haematologica 108 (2), 502-512 (2023)
   PUBMED   35924577
  REMARK    GeneRIF: ARID5B influences B-cell development and function in
            mouse.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4494)
  AUTHORS   Murray,J., Ehsani,A., Najjar,L., Zhang,G. and Itakura,K.
  TITLE     Muscle-specific deletion of Arid5b causes metabolic changes in
            skeletal muscle that affect adipose tissue and liver
  JOURNAL   Front Endocrinol (Lausanne) 13, 1083311 (2023)
   PUBMED   36743919
  REMARK    GeneRIF: Muscle-specific deletion of Arid5b causes metabolic
            changes in skeletal muscle that affect adipose tissue and liver.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4494)
  AUTHORS   Whitson,R.H. Jr., Li,S.L., Zhang,G., Larson,G.P. and Itakura,K.
  TITLE     Mice with Fabp4-Cre ablation of Arid5b are resistant to
            diet-induced obesity and hepatic steatosis
  JOURNAL   Mol Cell Endocrinol 528, 111246 (2021)
   PUBMED   33757861
  REMARK    GeneRIF: Mice with Fabp4-Cre ablation of Arid5b are resistant to
            diet-induced obesity and hepatic steatosis.
REFERENCE   5  (bases 1 to 4494)
  AUTHORS   Suzuki,A., Abdallah,N., Gajera,M., Jun,G., Jia,P., Zhao,Z. and
            Iwata,J.
  TITLE     Genes and microRNAs associated with mouse cleft palate: A
            systematic review and bioinformatics analysis
  JOURNAL   Mech Dev 150, 21-27 (2018)
   PUBMED   29475039
REFERENCE   6  (bases 1 to 4494)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 4494)
  AUTHORS   Watanabe,M., Layne,M.D., Hsieh,C.M., Maemura,K., Gray,S., Lee,M.E.
            and Jain,M.K.
  TITLE     Regulation of smooth muscle cell differentiation by AT-rich
            interaction domain transcription factors Mrf2alpha and Mrf2beta
  JOURNAL   Circ Res 91 (5), 382-389 (2002)
   PUBMED   12215486
REFERENCE   8  (bases 1 to 4494)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   9  (bases 1 to 4494)
  AUTHORS   Lahoud,M.H., Ristevski,S., Venter,D.J., Jermiin,L.S.,
            Bertoncello,I., Zavarsek,S., Hasthorpe,S., Drago,J., de Kretser,D.,
            Hertzog,P.J. and Kola,I.
  TITLE     Gene targeting of Desrt, a novel ARID class DNA-binding protein,
            causes growth retardation and abnormal development of reproductive
            organs
  JOURNAL   Genome Res 11 (8), 1327-1334 (2001)
   PUBMED   11483573
REFERENCE   10 (bases 1 to 4494)
  AUTHORS   Ristevski,S., Tam,P.P., Kola,I. and Hertzog,P.
  TITLE     Desrt, an AT-rich interaction domain family transcription factor
            gene, is an early marker for nephrogenic mesoderm and is expressed
            dynamically during mouse limb development
  JOURNAL   Mech Dev 104 (1-2), 139-142 (2001)
   PUBMED   11404092
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY717211.1, BY720203.1, AK029818.1, CN665657.1, CD543091.1 and
            AK034633.1.
            
            On or before Dec 7, 2005 this sequence version replaced
            XM_920585.1, XM_920592.1, XM_920598.1, XM_907858.1, NM_023598.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF280065.1, SRR7345562.3136122.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-292               BY717211.1         2-293
            293-749             BY720203.1         19-475
            750-1038            AK029818.1         882-1170
            1039-1126           CN665657.1         1-88
            1127-1708           CD543091.1         1-582
            1709-4494           AK034633.1         113-2898
FEATURES             Location/Qualifiers
     source          1..4494
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 35.14 cM"
     gene            1..4494
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /note="AT-rich interaction domain 5B"
                     /db_xref="GeneID:71371"
                     /db_xref="MGI:MGI:2175912"
     exon            1..37
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..3583
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /note="AT rich interactive domain 5B (Mrf1 like);
                     modulator recognition factor 2; ARID class DNA binding
                     protein; MRF-2; ARID domain-containing protein 5B;
                     modulator recognition factor protein 2; developmentally
                     and sexually retarded with transient immune abnormalities
                     protein; AT rich interactive domain 5B (MRF1-like)"
                     /codon_start=1
                     /product="AT-rich interactive domain-containing protein
                     5B"
                     /protein_id="NP_076087.2"
                     /db_xref="CCDS:CCDS35929.1"
                     /db_xref="GeneID:71371"
                     /db_xref="MGI:MGI:2175912"
                     /translation="MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFV
                     RCTPKDPICIAELQLLWEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKV
                     IVKLEDLVKWAHSDFSKWRCGLRATPVKTEAFGRNGQKEALLRYRQSTLNSGLNFKDV
                     LKEKADLGEDEEETNVIVLSYPQYCRYRSMLKRIQDKPSSILTDQFALALGGIAVVSR
                     NPQILYCRDTFDHPTLIENESVCDEFAPNLKGRPRKKKTCPQRRDSFSGSKDPNNNCD
                     GKVISKVKGEARSALTKPKNNHNNCKKTSNEEKPKLSIGEECRADEQAFLVALYKYMK
                     ERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAA
                     TCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENNTQENENKTKVSGNKRIKQEMA
                     KNKKEKENTPKPQDTSEVSSEQRKEEETLNHKSAPEPLPAPEVKGKPEGHKDLGARAP
                     VSRADPEKANETDQGSNSEKEAEEMGDKGLAPLLPSPPLPPEKDSAPTPGAGKQPLAS
                     PSTQMDSKQEAKPCCFTESPEKDLQGAPFSSFSATKPPLTSQNEAEEEQLPATANYIA
                     NCTVKVDQLGSDDIHTALKQTPKVLVVQSFDMFKDKDLTGPMNENHGLNYTPLLYSRG
                     NPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIAREDLCSGLSQGHHSQS
                     SDHTAVSRPSVIQHVQSFKNKASEDRKSINDIFKHDKLSRSDAHRCGFSKHQLGSLAD
                     SYILKQETQEGKDKLLEKRAVSHAHVPSFLADFYSSPHLHSLYRHTEHHLHNEQSSKY
                     AARDAYQESENGAFLSHKHPEKIHVNYLASLHLQDKKVAAAEASTDDQPTDLSLPKNP
                     HKLTSKVLGLAHSTSGSQEIKGASQFQVVSNQSRDCHPKACRVSPMTMSGPKKYPESL
                     ARSGKPHQVRLENFRKMEGMVHPILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARA
                     VSPLDPAKEASGKEKASEQESEGNKGAYGGHSGAASEGHKLPLSTPIFPGLYSGSLCN
                     SGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAA
                     ATPVGSSYGDLLHNSIYPLAGINPQAAFPSSQLSSVHPSTKL"
     exon            38..292
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     exon            293..518
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     exon            519..749
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     exon            750..862
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     exon            863..1067
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1120
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1121..1218
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1417
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1418..4494
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4053..4058
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /note="hexamer: ATTAAA"
     polyA_site      4075
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
     regulatory      4268..4273
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /note="hexamer: ATTAAA"
     polyA_site      4293
                     /gene="Arid5b"
                     /gene_synonym="4930580B11; 5430435G07Rik; Desrt; Mrf2;
                     Mrf2alpha; Mrf2beta"
                     /note="major polyA site"
ORIGIN      
        1 aattcagaac gtcgagatgg agcccaactc actccagtgg gtcggctcac cgtgtggctt
       61 gcacggacct tatatttttt ataaggcttt tcaattccac cttgaaggca aaccaagaat
      121 cttgtccctt ggcgactttt tctttgtaag atgtacgcca aaggatccga tttgcatagc
      181 ggagctccag ctgttgtggg aagaaaggac cagccggcaa cttttatcca gctcgaaact
      241 ttatttcctc cccgaagaca ctccccaggg cagaaatagc gaccatggcg aggatgaggt
      301 catcgctgtc tctgaaaagg tgattgttaa attagaggac cttgtcaaat gggcgcattc
      361 tgatttctcc aagtggaggt gtgggctccg agccactcca gtgaaaactg aggccttcgg
      421 gagaaacgga cagaaggagg ctctgctcag gtacaggcag tcaaccctca acagtgggct
      481 caacttcaaa gacgttctca aggaaaaagc tgatctcggg gaagatgagg aagaaaccaa
      541 cgtgattgtg ctcagttacc cccagtactg tcggtaccgg tccatgctta aacggatcca
      601 ggataagcca tcgtccatcc tcacggacca gttcgcatta gccctggggg gcatcgcagt
      661 ggtcagcaga aacccccaga tcctgtactg ccgggatacc tttgatcacc ccactctgat
      721 agaaaacgag agtgtgtgtg atgagttcgc gccaaatctt aaaggcagac cacgcaaaaa
      781 gaaaacatgt ccccagagaa gagattcctt cagtggctca aaggacccca acaataactg
      841 tgacggtaaa gttatcagca aggtgaaagg agaggccagg tcagccttga ccaagccgaa
      901 gaataaccac aataactgta aaaaaacctc aaatgaagaa aagccaaagc tgtctattgg
      961 cgaagaatgc agggcagatg aacaagcctt cttagtggcc ctgtataaat acatgaaaga
     1021 aagaaaaacg cccatcgagc gaattcccta cttgggtttc aaacagatta acctttggac
     1081 tatgtttcaa gctgctcaaa aactgggagg atatgaaaca ataacagccc gccgtcagtg
     1141 gaaacatatt tatgacgagt taggtggtaa tcctgggagc accagtgcgg ccacctgtac
     1201 tcgcagacac tacgaaaggt taatcctgcc atacgaaaga tttattaagg gagaagaaga
     1261 taagcctctg ccgccaatca aacctcggaa acaggaaaac aatacacagg aaaatgagaa
     1321 taaaacaaaa gtctcgggaa acaaacgtat caaacaggaa atggccaaaa acaagaaaga
     1381 aaaagagaac acccccaaac cccaagatac atctgaggtt tcatcagagc aaaggaagga
     1441 agaagagacg ttaaaccaca aaagcgcccc cgagcctctc cctgctcctg aagtaaaggg
     1501 gaaaccagaa gggcacaagg atcttggagc gagggcccca gtgtccagag cagacccaga
     1561 aaaggccaat gaaactgacc aaggttccaa cagcgagaaa gaggccgagg agatgggaga
     1621 taagggcctt gcccctctgc ttccaagccc tcccttgcct cctgaaaaag attcagctcc
     1681 cacccctggg gctggcaaac agccccttgc ctctcccagc acccagatgg actcaaagca
     1741 agaagccaaa ccctgctgct ttacagagag ccctgagaag gacctccaag gagcaccctt
     1801 ctccagcttc tctgccacca agccaccact gacaagccag aacgaggcag aggaagagca
     1861 gcttcctgcc acggccaact acattgccaa ctgcactgtg aaggtggacc agctgggcag
     1921 tgacgacatc cacactgctc tcaagcagac cccgaaggtc cttgtggtcc aatcatttga
     1981 catgttcaaa gacaaagact tgaccggccc catgaatgag aaccacggac ttaactacac
     2041 gcccctgctt tactcccggg gcaaccctgg tatcatgtcc ccattggcta agaaaaagct
     2101 tttgtctcag gtgagtgggg ccagcctctc cagcagctat ccctatggct ccccgccccc
     2161 tttgatcagc aaaaagaaac tcattgccag ggaagacctg tgctcgggtt tgtcccaggg
     2221 ccaccacagc caaagctctg accacacggc cgtcagccgg ccatccgtaa tccaacatgt
     2281 tcagagcttc aaaaacaagg cctccgaaga cagaaagagc atcaacgaca tcttcaagca
     2341 cgacaaactg agccggtccg atgctcatcg atgtggcttc tccaagcacc agctcggctc
     2401 cctggcagac tcctacatcc tcaaacaaga gacacaggag ggcaaagata aactgttaga
     2461 gaagagagcc gtctcccacg cccatgtgcc cagtttcctg gccgacttct actcatcccc
     2521 gcatctccat agcctctacc ggcacacaga gcaccatctt cacaacgaac agtcctccaa
     2581 gtatgccgct agggacgcgt accaggaatc cgaaaacggc gcctttcttt ctcacaagca
     2641 cccggagaag atccacgtca attatctcgc atctctccac ctgcaagata agaaggtggc
     2701 agcggcagaa gcctctaccg atgatcaacc cacagatctg agccttccca agaacccaca
     2761 taaactaacc agcaaagtcc tgggcctggc ccactccacc tcggggtccc aggagatcaa
     2821 aggcgcctcc cagttccagg tcgtcagcaa ccagagtcga gactgtcatc ccaaagcctg
     2881 ccgggtatcg cccatgacca tgtcgggccc taagaaatac cctgagtcac ttgcaaggtc
     2941 aggaaagcct caccaggtga gactggagaa cttcaggaaa atggaaggca tggtccatcc
     3001 catcctgcac cggaagatga gcccgcagaa cattggagct gcgcgcccca taaagcgcag
     3061 cctggaggat ttagatctgg tgatcgccgg gaaaaaggcc agggctgtgt ctcccttgga
     3121 cccagccaag gaggcttctg ggaaagaaaa ggcctccgaa caggagagcg agggcaacaa
     3181 aggcgcctac ggtgggcatt ctggggctgc ctcagaaggg cacaagctcc ctctctccac
     3241 ccctatcttc ccgggtttgt attctgggag cctgtgtaat tcaggcctca actccaggct
     3301 cccggccggg tactcccatt ctctgcagta cttgaagaac cagacggtgc tttctcctct
     3361 catgcaaccc ctggctttcc actcgctcgt gatgcagaga ggaattttta catcgccgac
     3421 aaattctcag cagctgtaca gacacttggc cgcagccacc cctgtaggaa gttcctacgg
     3481 ggacctgttg cacaacagca tctacccatt agctggtatc aaccctcagg ctgccttccc
     3541 atcttctcag ctgtcatccg tacaccccag cacaaaactg taagcctcga tttgcccagc
     3601 atccccaaat ggtgtggtcc attgcaccaa ctcttggagg ggctggcttg caaagttgga
     3661 agtcagtatt ccttctgatc tggtttcgcc ccagccatag aggtgtacat acctaccttt
     3721 tcggggacaa ccctagcctg actgaccaat tgtgacctct cccttccaac acagatggcc
     3781 tagggcctgg gggtcattgt cttttcacgt tggtcctgtg aaggtatctg tggtctatcc
     3841 tagaagaacg cagaggaccc catctgagtt tggatggtaa ggaagcaact tgagcataaa
     3901 gttctggggt gggggaggca ggcttttcaa aggcaagggc aagaaagact ggcacggaat
     3961 agccagggga tgcccgtctt tttcatcaaa ctcaccaagt tcaatcaatg caatgtatag
     4021 taaaacttaa agagaccttt cattctgaca ctattaaaca atccagagaa ggaaacactg
     4081 ttaaactgta tatattcgct tcttaaagct acccgtatca ctgttggctc acctaattta
     4141 tatacaggta gttgtgtttc cctcccggtt ccttcttgtt cctgccctag ggtttttttt
     4201 gttttgtttt tgtttttttt tgtttttttt ggtttgtgta tctgtttgtt tgtttgtttg
     4261 ttttttaatt aaacagcatc ccttctgttt gtaggtcttt tgatttgttt tgttctgttt
     4321 gtaaggctga ctgattcttc tagttgtcaa tgtgtattct atcaacccca ccccaggccc
     4381 cgtccccgtc cccaccacat cttcttttga gcagctttgg gtggtcaagt tattgtttac
     4441 aaattgaagc aactgatttt agtggaacag actgtaaaga accccccccc cccc
//
