LOCUS       NM_175251               9029 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus AT-rich interaction domain 2 (Arid2), mRNA.
ACCESSION   NM_175251
VERSION     NM_175251.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9029)
  AUTHORS   Martinez-Mayer,J., Brinkmeier,M.L., O'Connell,S.P., Ukagwu,A.,
            Marti,M.A., Miras,M., Forclaz,M.V., Benzrihen,M.G., Cheung,L.Y.M.,
            Camper,S.A., Ellsworth,B.S., Raetzman,L.T., Perez-Millan,M.I. and
            Davis,S.W.
  TITLE     Knockout mice with pituitary malformations help identify human
            cases of hypopituitarism
  JOURNAL   Genome Med 16 (1), 75 (2024)
   PUBMED   38822427
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9029)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 9029)
  AUTHORS   Boogerd,C.J., Perini,I., Kyriakopoulou,E., Han,S.J., La,P., van der
            Swaan,B., Berkhout,J.B., Versteeg,D., Monshouwer-Kloots,J. and van
            Rooij,E.
  TITLE     Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP
            inhibition during cardiac maturation
  JOURNAL   Nat Commun 14 (1), 4716 (2023)
   PUBMED   37543677
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 9029)
  AUTHORS   Cao,H.J., Jiang,H., Ding,K., Qiu,X.S., Ma,N., Zhang,F.K.,
            Wang,Y.K., Zheng,Q.W., Xia,J., Ni,Q.Z., Xu,S., Zhu,B., Ding,X.F.,
            Chen,T.W., Qiu,L., Chen,W., Li,Z.G., Zhou,B., Feng,W.M., Xie,D. and
            Li,J.J.
  TITLE     ARID2 mitigates hepatic steatosis via promoting the ubiquitination
            of JAK2
  JOURNAL   Cell Death Differ 30 (2), 383-396 (2023)
   PUBMED   36396719
  REMARK    GeneRIF: ARID2 mitigates hepatic steatosis via promoting the
            ubiquitination of JAK2.
REFERENCE   5  (bases 1 to 9029)
  AUTHORS   Li,W., An,N., Wang,M., Liu,X. and Mei,Z.
  TITLE     Downregulation of AT-rich interaction domain 2 underlies natural
            killer cell dysfunction in oral squamous cell carcinoma
  JOURNAL   Immunol Cell Biol 101 (1), 78-90 (2023)
   PUBMED   36269235
  REMARK    GeneRIF: Downregulation of AT-rich interaction domain 2 underlies
            natural killer cell dysfunction in oral squamous cell carcinoma.
REFERENCE   6  (bases 1 to 9029)
  AUTHORS   Zhang,H.S., Gavin,M., Dahiya,A., Postigo,A.A., Ma,D., Luo,R.X.,
            Harbour,J.W. and Dean,D.C.
  TITLE     Exit from G1 and S phase of the cell cycle is regulated by
            repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
  JOURNAL   Cell 101 (1), 79-89 (2000)
   PUBMED   10778858
REFERENCE   7  (bases 1 to 9029)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   8  (bases 1 to 9029)
  AUTHORS   Phelan,M.L., Sif,S., Narlikar,G.J. and Kingston,R.E.
  TITLE     Reconstitution of a core chromatin remodeling complex from SWI/SNF
            subunits
  JOURNAL   Mol Cell 3 (2), 247-253 (1999)
   PUBMED   10078207
REFERENCE   9  (bases 1 to 9029)
  AUTHORS   Reyes,J.C., Muchardt,C. and Yaniv,M.
  TITLE     Components of the human SWI/SNF complex are enriched in active
            chromatin and are associated with the nuclear matrix
  JOURNAL   J Cell Biol 137 (2), 263-274 (1997)
   PUBMED   9128241
REFERENCE   10 (bases 1 to 9029)
  AUTHORS   Wang,W., Xue,Y., Zhou,S., Kuo,A., Cairns,B.R. and Crabtree,G.R.
  TITLE     Diversity and specialization of mammalian SWI/SNF complexes
  JOURNAL   Genes Dev 10 (17), 2117-2130 (1996)
   PUBMED   8804307
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK007269.1, BU056807.1, CK781204.1, CA749551.1, CV559640.1,
            AC133578.12 and AK077366.1.
            
            On Mar 16, 2012 this sequence version replaced NM_175251.3.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus to one that is more supported by available conservation
            data. This update was done because it was determined that the
            previous CCDS version represented a partial protein coding region,
            based on comparison to protein homologs including NP_689854.2. The
            use of an alternative upstream start codon would result in a
            protein that is 190 aa longer at the N-terminal.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849375,
                              SAMN00849380 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-193               AK007269.1         3-195
            194-929             BU056807.1         1-736
            930-1283            CK781204.1         292-645
            1284-1901           CA749551.1         33-650
            1902-2486           CV559640.1         167-751
            2487-4928           AC133578.12        45678-48119         c
            4929-5862           AK077366.1         1691-2624
            5863-9029           AC133578.12        12977-16143         c
FEATURES             Location/Qualifiers
     source          1..9029
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 52.37 cM"
     gene            1..9029
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /note="AT-rich interaction domain 2"
                     /db_xref="GeneID:77044"
                     /db_xref="MGI:MGI:1924294"
     exon            1..265
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     CDS             174..5660
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /note="AT rich interactive domain 2 (Arid-rfx like);
                     zipzap; BRG1-associated factor 200; ARID domain-containing
                     protein 2; zinc finger protein with activation potential;
                     AT rich interactive domain 2 (ARID, RFX-like)"
                     /codon_start=1
                     /product="AT-rich interactive domain-containing protein 2"
                     /protein_id="NP_780460.3"
                     /db_xref="CCDS:CCDS37185.2"
                     /db_xref="GeneID:77044"
                     /db_xref="MGI:MGI:1924294"
                     /translation="MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKE
                     LDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEK
                     VHHFGEDDDEVPPGNPKPQLPIGAIPSSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNK
                     LVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFS
                     SVFGEEWREKTDRDFVKFWKDIVDDNEVRDLISDRNKAHEDTPGEWIWESLFHPPRKL
                     GINDIEGQRVLQIAVILRNLSFEESNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDT
                     LGNIAAELLLDPVDFRTTHLMFHTVTKCLMSRDRFLKMRGMEILGNLCKAEDNGVLIC
                     EYVDQDSYREIICHLTLPDVLLVTSTLEVLYMLTEMGDVACTKIAKVEKSIDVLVCLV
                     SMDAQMFGPDALAAVKLIEHPSSSHQVLSEIRPQAIEQVQTQTHIASGPASRAVVAQH
                     AAPPPGIVEIDSEKFACQWLNAHFEVNPDCSVSRAEMYSEYLSTCSKLARGGILTSTG
                     FYKCLRTVFPNHTVKRVEDSTSSGQAHIHVIGVKRRALPLPIQMYYQQQPISTPVVRV
                     DAVADLSPTPSPAGIPHGPQAAGNHFQRTPVTNQSSNLTATQMSFPVQGIHTVAQTVS
                     RIPPNPSVHTHQQQNSPVTVIQNKAPIPCEVVKATVIQNSVPQTAVPVSISVGGAPAQ
                     NSVGQNHSAGPQPVTVVNSQTLLHHPSVMPQPSPLHTVVPGQVPSGTPVTVIQQTVPQ
                     SRMFGRVQSIPACTSTVSQGQQLITTSPQPMHTSSQQTAAGSQPQDTVIIAPPQYVTT
                     SASNIVSATSVQNFQVATGQVVTIAGVPSPQPSRVGFQNIAPKPLPSQQVSPSVVQQP
                     IQQPQQPAQQSVVIVSQPAQQGQAYAPAIHQIVLANPAALPAGQTVQLTGQPNITPSS
                     SPSPVPPTNNQVPTAMSSSSTLQSQGPPPTVSQMLSVKRQQQQQHSPAAPAQQVQVQV
                     QQPQQVQVQVQPQQPSAGVGQPAPNESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPN
                     NARAPSPQVVYQVANNQAAGFGVQGQTPAQQLLVGQQNVQLVQSAMPPAGGVQTVPIS
                     NLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFATATVSQGNAAQLIAPAGLSMS
                     GAQASAGLQVQTLPAGQSACTTAPLPFKGDKIICQKEEEAKEATGLHVHERKIEVMEN
                     PSCRRGTTNTSNGDTSESELQVGSLLNGRKYSDSSLPPSNSGKLQSETSQCSLISNGP
                     SLELGENGAPGKQNSEPVDMQDVKGDLKKALVNGICDFDKGDGSHLSKNIPNHKTSNH
                     VGNGEISPVEPQGTSGATQQDTAKGDQLERVSNGPVLTLGGSPSTSSMQEAPSVATPP
                     LSGTDLPNGPLASSLNSDVPQQRPSVVVSPHSTAPVIQGHQVIAVPHSGPRVTPSALS
                     SDARSTNGTAECKTVKRPAEDNDRDTVPGIPNKVGVRIVTISDPNNAGCSATMVAVPA
                     GADPSTVAKVAIESAAQQKQQHPPTYMQSVAPQNTPMPPSPAVQVQGQPSSSQPSPVS
                     ASSQHADPVRKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEP
                     FQRQRFSFITHLQDKHCSKDALLAGLKQDEPGQVANQKSSTKQPTVGGTGSAPRAQKA
                     IASHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLL
                     KRHENNLSVLAISNMEASSTLAKCLYELNFTVQSKEQEKDSEML"
     exon            266..359
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            360..457
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            458..591
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            592..810
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            811..878
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            879..945
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1196
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1293
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1503
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            1504..1671
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1753
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            1754..1888
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..2085
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..4928
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            4929..5077
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            5078..5216
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            5217..5302
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            5303..5426
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            5427..5518
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     exon            5519..9029
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7149..7154
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /note="hexamer: AATAAA"
     polyA_site      7167
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /note="major polyA site"
     regulatory      8362..8367
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /note="hexamer: AATAAA"
     polyA_site      8386
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
     regulatory      8535..8540
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /note="hexamer: AATAAA"
     polyA_site      8557
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
     regulatory      8599..8604
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
                     /note="hexamer: AATAAA"
     polyA_site      8619
                     /gene="Arid2"
                     /gene_synonym="1700124K17Rik; 4432409D24Rik; BAF200;
                     zipzap/p200"
ORIGIN      
        1 gcgccgccgc cgccgccgcc gccgccgccg ccgccgccac cgccggccca tgactgagcc
       61 ccgccaccgc cggccgagga atgggctccg ggcgctggta gggagcgcgg ggagcggggg
      121 ccgcgtttga accgcgatct gggttttttc gggagacctc ctttggcaaa ataatggcaa
      181 actcgacggg gaaggcgcct ccggacgagc ggaggaaggg actggctttc ctggacgagc
      241 tgcggcagtt ccaccacagc agagggtcgc cgtttaagaa gatccctgcg gtgggtggga
      301 aggagctgga tcttcacggg ctctacacca gagtcactac tttaggcgga ttcgcgaagg
      361 tttctgagaa gaatcagtgg ggagaaattg ttgaagagtt caactttccc agaagttgtt
      421 ccaacgctgc ctttgcttta aaacagtatt acttgcgtta tctagaaaag tacgagaaag
      481 ttcatcattt tggggaagat gatgatgagg taccaccagg caatccaaag ccacagcttc
      541 ctattggtgc aatcccatct tcctacaatt accagcaaca cagcgtgtca gattatctac
      601 gtcaaagtta tgggttatct atggatttta attcgccaaa tgattataat aaactggtgc
      661 tttcactgtt atctggactc ccaaatgaag tggacttcgc tattaatgtg tgcactctcc
      721 tatcaaatga aagcaagcac gtcatgcagc ttgagaagga tcccaaaatc atcactttac
      781 tgctcgctaa tgcgggggtg ttcgatgaca ctttaggatc attctcttct gtctttggag
      841 aagagtggcg agagaagact gatagagact ttgttaagtt ttggaaagac attgttgatg
      901 acaatgaagt gcgagatctc atttctgaca gaaacaaggc tcatgaagat acaccaggag
      961 aatggatttg ggaatcttta tttcatccac ctcgaaagct gggcattaat gacatcgaag
     1021 gccagcgggt tctgcagatc gcagtgatct tgcggaacct ctcctttgag gagagcaatg
     1081 ttaagctctt ggcagctaat cgcacctgtc tgcgtttcct gttgctctct gcacacagtc
     1141 attttatttc attaaggcag ctaggcctgg acaccttagg gaatatcgca gctgagcttt
     1201 tactggaccc tgtggatttc agaaccactc atctgatgtt tcacactgtt acaaaatgcc
     1261 tgatgtcaag ggataggttt ttaaagatga ggggcatgga aattttggga aatctctgca
     1321 aagcagagga taacggtgtt ttgatttgtg aatatgtgga tcaagattcc tatagagaga
     1381 taatttgtca cctcactctg cccgatgtgc tgctggtgac ctcaaccctg gaggtgctgt
     1441 acatgctcac tgaaatgggg gacgtggcct gcacaaagat cgcgaaagtg gagaagagca
     1501 tagacgtgct ggtgtgtctg gtctctatgg acgctcagat gtttggacct gacgcacttg
     1561 ctgccgtgaa gctcattgag catccgagct ccagtcacca agtgttatca gagattaggc
     1621 cgcaagccat agagcaggtc caaacccaga cccacatagc ctccggtcca gcttccagag
     1681 cagttgtagc acagcatgct gccccccctc caggaatcgt ggaaatagac agtgagaagt
     1741 tcgcttgtca gtggctaaat gctcattttg aagtaaatcc agactgttcc gtctctcggg
     1801 cagaaatgta ttcagagtac ctctcaactt gcagtaaatt agctcgcggt ggcatcctca
     1861 catcaactgg gttttataag tgtcttagaa cagtttttcc aaatcataca gtgaagaggg
     1921 tagaagattc cactagcagt gggcaggcgc atatccatgt cataggagtg aagcggcggg
     1981 ctctcccgct ccccatccag atgtactatc agcagcagcc aatttccact cctgttgtcc
     2041 gtgttgatgc tgttgctgat ctatctccaa ctccttcacc tgcaggaatc cctcatggac
     2101 cacaggctgc agggaatcat tttcagagga ctcctgtcac caatcaatct tcaaatttga
     2161 ctgcaacaca aatgtctttt ccggtacaag gcattcatac tgtggcacag actgtttcca
     2221 gaattccacc aaatccttca gttcataccc accagcaaca aaattctcca gtaactgtca
     2281 ttcagaataa agctccaatt ccttgtgaag tcgttaaggc aacagtaatc cagaactctg
     2341 tgccccagac ggcagttcct gtgagtatct ctgttggagg agcacctgca cagaattctg
     2401 tgggtcagaa ccatagtgca gggccacagc ctgttacagt tgtaaattct cagacattac
     2461 ttcaccatcc ttctgtgatg ccacagccat ctccactaca cacagtggtg cccggacagg
     2521 tcccttcagg cactcctgtc acagtaatcc agcagactgt accgcagagt cgtatgtttg
     2581 gacgagtaca gagcatacca gcgtgtacat ctaccgtctc acagggtcag cagttaatca
     2641 ccacatcacc acagcctatg cacacttcat ctcaacagac agcagctggt agccagccac
     2701 aagacactgt tatcatagca cccccacagt acgtaacaac ttctgcatcc aatatcgtct
     2761 cagcgacttc agtacagaat ttccaggtag ctacaggaca ggtggttacc atagctggtg
     2821 tcccgagccc acagccctcc agggtaggat tccagaacat tgcgcccaag ccacttcctt
     2881 ctcagcaagt ttcaccatca gtggtccagc agcctattca acaaccacag cagcctgctc
     2941 agcagagtgt agtgattgtg agccagccag cacagcaagg ccaggcgtac gcaccagcca
     3001 ttcaccagat cgttctcgct aacccggcag ctctccctgc cggtcagacg gttcagctaa
     3061 ctggacaacc aaacataact ccatcgtcat caccatcacc tgtcccgcct actaataacc
     3121 aagtccctac tgccatgtca tcttcttcca cccttcagtc acagggaccc cctcctactg
     3181 tcagtcagat gctctctgtg aagaggcagc agcagcagca gcactcacca gcagcgccag
     3241 cacagcaggt ccaggtccag gttcagcagc cgcagcaggt ccaggtgcaa gttcagccgc
     3301 agcaaccgag tgctggggtc ggtcagcctg ctcccaacga gtctagtctc atcaagcagc
     3361 tgctgctgcc aaagcggggc ccttcaaccc cagggggcaa gcttatcctc ccagcccctc
     3421 agattcctcc ccctaacaat gcaagagctc ctagccctca ggtggtctat caggtggcca
     3481 ataaccaagc agctggtttt ggagtgcagg ggcaaactcc ggctcagcag ctattggttg
     3541 ggcagcaaaa tgttcagttg gtccaaagtg caatgccacc cgcaggggga gtgcaaaccg
     3601 tgcccatttc gaacttacaa atattgccgg gtccgctgat ctcaaacagc ccagcaacca
     3661 ttttccaagg gacttctggc aaccaggtaa ctataacagt tgtgccaaat accagttttg
     3721 caactgcgac tgtgagtcag ggaaacgctg ctcagctcat tgcgccagcc ggtcttagca
     3781 tgagcggagc gcaggcaagc gctggacttc aggtgcagac gcttccagcc ggacaatcag
     3841 cgtgtaccac tgctcccctc ccgttcaaag gcgacaagat catttgccaa aaggaggagg
     3901 aggcaaagga agcaacaggt ctacatgttc atgaacggaa gattgaggtc atggagaatc
     3961 cttcctgtcg gcgaggaacc acaaacacca gcaacgggga tacaagtgag agtgaactcc
     4021 aggtgggaag tcttttaaat gggagaaagt atagtgactc aagtctacct ccttcaaact
     4081 cagggaaact tcagagtgag acgagccagt gctcactaat cagcaatggg ccatcgttgg
     4141 aactaggtga gaatggagcg cctggaaaac agaactcaga accagtagac atgcaggatg
     4201 tcaaaggtga tctgaaaaaa gccctcgtca atggaatctg tgattttgat aaaggagatg
     4261 gttctcattt aagcaaaaac attccaaatc acaaaacttc taatcatgta ggaaatggtg
     4321 agatatctcc agtagaacca caagggactt cgggtgccac tcagcaagat actgccaaag
     4381 gtgaccaact agaaagagtt tctaatggac ctgtgttaac tctgggtggg tcaccgtcca
     4441 caagcagtat gcaagaagcc ccgagtgtgg cgacaccgcc gttgagtggt actgacctgc
     4501 ctaacggacc tctagcttca agtttgaatt cagatgtgcc tcagcaacgc ccaagtgtag
     4561 ttgtctcacc acattctaca gcccctgtca tacaggggca tcaagtcata gcagttcccc
     4621 actcaggacc tagagtgacc ccttctgctc tatcatctga tgctcggtct acaaacggca
     4681 cagccgagtg caaaactgta aagaggccgg cagaggataa tgatagggac actgtcccgg
     4741 gaatcccaaa taaagtaggg gttagaattg ttacaatcag cgaccccaac aatgctggct
     4801 gcagtgcaac catggttgcg gtcccagctg gagcggaccc aagcactgta gcgaaagtag
     4861 caatagaaag tgctgctcag caaaagcagc agcatccacc gacctacatg cagagtgtgg
     4921 ccccacagaa cactcctatg ccaccttcac cagctgtaca agtgcagggc cagcctagca
     4981 gttctcagcc ttctccagtc agtgcgtcca gtcagcatgc agatccagtg agaaaacctg
     5041 ggcagaactt catgtgtctg tggcagtctt gtaaaaagtg gtttcagact ccctcacaag
     5101 tgttctatca tgcagctact gaacatggag gaaaagatgt gtatccgggg cagtgtcttt
     5161 gggaaggctg tgagcctttc caacggcaga ggttctcttt cattacccac ttacaggata
     5221 agcactgttc aaaggatgcc ctgcttgcag gattaaagca agatgaacca ggacaagtgg
     5281 caaatcaaaa atcttctacc aagcagccca ccgtgggggg cacaggctct gcgcccagag
     5341 cccagaaggc cattgcaagc caccccagtg ctgcactcat ggctctgcgg agaggctcaa
     5401 ggaacctcgt cttccgggac ttcacagatg aaaaagaggg accaataact aaacacatcc
     5461 gactaacagc tgccttaata ttaaaaaata ttggtaaata ctcagagtgt gggcgcagat
     5521 tgttaaagag acatgaaaac aacttatcag tgctcgccat tagtaacatg gaagcttcct
     5581 ctacccttgc caaatgcctt tatgaactta attttacagt tcagagtaaa gaacaagaaa
     5641 aagactcaga aatgctgtag tgaatcctac cccactgaca cagtggggtc tcaaagtcaa
     5701 atacatttca catactgtta ctgaagaaag caccaagtct taatggagca gagaccatag
     5761 aatgaattat tttgtgtcct ccatgatgct gagaggaaac ttcgtattct gatctctgaa
     5821 cgaatccctt tcttttctgt taaaaaaaaa aaatctaaaa aggaaaaaaa aaaaaaaaaa
     5881 aacaaaaact gctgtgggat tgtcaaccag cttatctgca ggatgtctcg gatctggcca
     5941 atcctgatgg aaactggtgt gatcagaatt ctgtaccatc cacattggaa tatacatgga
     6001 atagtgtaaa acctacgtga gcagatgaaa tagaagcatt aaatattttt atctatatcc
     6061 aaaaaggagc acatttttat atttacagaa ccatttaagc tggtttgaat aacgacagag
     6121 tttgagcaca cctatccccc agcttcagag gggccaccaa tatctagctg tggattgtgt
     6181 gttttgttta gaatcagtag cttggttttc ttacttgagc caatatattt tcacttattt
     6241 attatcataa aaatttacca gtctgaatag atcttgtaaa tatttgtgaa tagaatgaac
     6301 actgttcata ccactgcagc cactggagat acatcctgtg gtgtcctaga agcattatcg
     6361 gtaggctcta aagttttcta gactttgctg tcaactgtaa gtaattgtga tatattctac
     6421 gcagtggatg gatattcttt aaatctgtgt aaatacttct gcaaaggtac tgatgctgta
     6481 aagtcaaaca gttttgtgga actgtgattt tttttttcct ccttttttgg tttccttggc
     6541 ccccacttgg gtttggtggg gttttgtttt tgttttgttt tgtattatac accttgtaga
     6601 actcattttg ctggctgaaa gagtatggaa taatatatct catatgtcat ttttgtagaa
     6661 gagaaactat ttggatttcc tttttgttgg tttggttttc cctaacacgt gtccgctgta
     6721 cgcattcgtc acgtgcaagc tcagcttgtg cagggttttt tgtatttgta aattggttta
     6781 aatacatgga attttataca ggttttctcc tgtgttatat atgcattatg tgcaggtatg
     6841 atattttctt cactactttt tctatcttaa tatagtgtgg aattttattg tattattctt
     6901 ccattcttaa tactgtacca cattcctgct cagaaactgc tcacttcctt aaattgtctt
     6961 ttcccccaag cgtgaaatgt atccacttat aactgcctat tgcctgttct attagcatcc
     7021 aaaaatgtgg aaggcctccc aaccaccatt tctgctgtgt ccttaggatg tgcagtaaaa
     7081 aaatatagac ctgacagttt atgttataga atggctttat ttactttggt gactgtttat
     7141 agtttttaaa taaaagactg aacattttct tgagtccttt atttctgagt atgcttaaga
     7201 cattctaaaa tttaaagtct agctgaaggc aaggtcaaac ggtcacctac ttactttata
     7261 ctttgtgatt gtagagaaca gaaaggtgca tcatgtgata ggacaccatg gtcacggtag
     7321 gaaggagacc aggagaccaa atgttttgtt tacagtagta tgagtagtag ccccagagag
     7381 cgagagacag ttagggctcg gttgccttac tgtgtgtccc gcatctatct gactgagagc
     7441 tttgtttacc attcgactct aggtttcagt ttaactaatt caggggcagc ttcttggcaa
     7501 tgagcttcag tctggacagt tcaaatatct tgattaattt agtaccaaaa agtaatttct
     7561 ccccaggggt ctctgtgctc tcagctctaa ctgtaagaaa tgtgtggcga cacccagaac
     7621 ttggtattct caggttggtg gcgtttgact tcttcgcctt agcctggggc tgcccagcag
     7681 acaccctgag tccaggtacc ttactgtatc cctcaaatat cgccagacta aaggtttcta
     7741 agggcagata gttgtagaaa tttatattca ctgtgtttat ctaaaaaaat tgaggttttt
     7801 gaaataattt ttgtaacatc actgtttgct tgtcctcaag gtaccttttt ccttccaaag
     7861 caggaaatta ccatggtggt tagcctttag tagcagaaac gacaggctta agaaagtggc
     7921 ttccatagtc accatcctgt cacctcactg aattgcatcc tgtagatgta gatttttgtg
     7981 ttaaaatgta taaatgtgtc tttagtgctt ttaagcaatg gtctcagcag aattttctaa
     8041 atgtatctga cctgacgaaa ccaatttcta gctcccctta ggcttcccct ccggcagctt
     8101 tacctgacta atggataaga cttggtgggt aacgcggttg aagtgctctt gcagtccagg
     8161 gcctgcagaa ccctcgcagt cacgaaaagg tgctccttgc tagacagaaa cttgctgact
     8221 tccagtattg ttatttttgt ctaaagttct gtaaatacaa gctttaatgt tatctttgag
     8281 agatctatgt aaataatagt caagaacata gagactgtac aattctgtgt tatatatgtg
     8341 cctagtgctc tgttggcact taataaattt taagtaacaa aactgatgat catatagtga
     8401 aggcatattt ttcttccgac ttgagacagg atatgactat atattaatga gactcaataa
     8461 accaagccac acatgaaaac ttgtctcatt actttatagc catgccatgt atgtttttta
     8521 aactataaaa tgacaataaa actgattttt gaaatgagtg ttttggataa gtgacttctg
     8581 tcctgatctt ataccataaa taaagtactg aagacgaaat atgaagctct tacccaaagg
     8641 agtagctgct tagaaacaag agtgaagctt gaagatcagc cacacaggcc acctcacact
     8701 ttgttcctgt ttatcttacg atacagtaag ggaaggcacc atttagagcc agcttgtgtt
     8761 agttaaccac tctcatactg cccaactctt gactgaactc tggcactcaa atacttggag
     8821 tgagcttcct tccaaggcca cagaacagag accaaccgaa ttaccagctg gttccatcat
     8881 agctagtaaa ctttatctag caacaatttc cactccctgc attggtttga aaaaaaaaat
     8941 gcaaagagac agtatcaatg tatgtaagtg gattcactaa taatacaacc acactttaag
     9001 tattaaagtg gggtgagatg gcttggtct
//
