LOCUS       NM_152801               4406 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus Rac/Cdc42 guanine nucleotide exchange factor 6
            (Arhgef6), transcript variant 1, mRNA.
ACCESSION   NM_152801
VERSION     NM_152801.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4406)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4406)
  AUTHORS   Klambt,V., Buerger,F., Wang,C., Naert,T., Richter,K., Nauth,T.,
            Weiss,A.C., Sieckmann,T., Lai,E., Connaughton,D.M., Seltzsam,S.,
            Mann,N., Majmundar,A.J., Wu,C.W., Onuchic-Whitford,A.C., Shril,S.,
            Schneider,S., Schierbaum,L., Dai,R., Bekheirnia,M.R., Joosten,M.,
            Shlomovitz,O., Vivante,A., Banne,E., Mane,S., Lifton,R.P.,
            Kirschner,K.M., Kispert,A., Rosenberger,G., Fischer,K.D.,
            Lienkamp,S.S., Zegers,M.M.P. and Hildebrandt,F.
  TITLE     Genetic Variants in ARHGEF6 Cause Congenital Anomalies of the
            Kidneys and Urinary Tract in Humans, Mice, and Frogs
  JOURNAL   J Am Soc Nephrol 34 (2), 273-290 (2023)
   PUBMED   36414417
  REMARK    GeneRIF: Genetic Variants in ARHGEF6 Cause Congenital Anomalies of
            the Kidneys and Urinary Tract in Humans, Mice, and Frogs.
REFERENCE   3  (bases 1 to 4406)
  AUTHORS   Mamula,D., Korthals,M., Hradsky,J., Gottfried,A., Fischer,K.D. and
            Tedford,K.
  TITLE     Arhgef6 (alpha-PIX) cytoskeletal regulator signals to GTPases and
            Cofilin to couple T cell migration speed and persistence
  JOURNAL   J Leukoc Biol 110 (5), 839-852 (2021)
   PUBMED   33527537
  REMARK    GeneRIF: Arhgef6 (alpha-PIX) cytoskeletal regulator signals to
            GTPases and Cofilin to couple T cell migration speed and
            persistence.
REFERENCE   4  (bases 1 to 4406)
  AUTHORS   Zhu,C., Cheng,C., Wang,Y., Muhammad,W., Liu,S., Zhu,W., Shao,B.,
            Zhang,Z., Yan,X., He,Q., Xu,Z., Yu,C., Qian,X., Lu,L., Zhang,S.,
            Zhang,Y., Xiong,W., Gao,X., Xu,Z. and Chai,R.
  TITLE     Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing
            Loss in Mice
  JOURNAL   Front Mol Neurosci 11, 362 (2018)
   PUBMED   30333726
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4406)
  AUTHORS   Tedford,K., Steiner,M., Koshutin,S., Richter,K., Tech,L.,
            Eggers,Y., Jansing,I., Schilling,K., Hauser,A.E., Korthals,M. and
            Fischer,K.D.
  TITLE     The opposing forces of shear flow and sphingosine-1-phosphate
            control marginal zone B cell shuttling
  JOURNAL   Nat Commun 8 (1), 2261 (2017)
   PUBMED   29273735
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4406)
  AUTHORS   Matsuda,C., Kameyama,K., Suzuki,A., Mishima,W., Yamaji,S.,
            Okamoto,H., Nishino,I. and Hayashi,Y.K.
  TITLE     Affixin activates Rac1 via betaPIX in C2C12 myoblast
  JOURNAL   FEBS Lett 582 (8), 1189-1196 (2008)
   PUBMED   18325335
REFERENCE   7  (bases 1 to 4406)
  AUTHORS   Node-Langlois,R., Muller,D. and Boda,B.
  TITLE     Sequential implication of the mental retardation proteins ARHGEF6
            and PAK3 in spine morphogenesis
  JOURNAL   J Cell Sci 119 (Pt 23), 4986-4993 (2006)
   PUBMED   17105769
  REMARK    GeneRIF: ARHGEF6 is localized in dendritic spines where it
            contributes to regulate dendritic spine morphogenesis.
REFERENCE   8  (bases 1 to 4406)
  AUTHORS   Feng,Q., Baird,D. and Cerione,R.A.
  TITLE     Novel regulatory mechanisms for the Dbl family guanine nucleotide
            exchange factor Cool-2/alpha-Pix
  JOURNAL   EMBO J 23 (17), 3492-3504 (2004)
   PUBMED   15306850
REFERENCE   9  (bases 1 to 4406)
  AUTHORS   Yoshizawa,M., Sone,M., Matsuo,N., Nagase,T., Ohara,O., Nabeshima,Y.
            and Hoshino,M.
  TITLE     Dynamic and coordinated expression profile of dbl-family guanine
            nucleotide exchange factors in the developing mouse brain
  JOURNAL   Gene Expr Patterns 3 (3), 375-381 (2003)
   PUBMED   12799088
REFERENCE   10 (bases 1 to 4406)
  AUTHORS   Kutsche,K. and Gal,A.
  TITLE     The mouse Arhgef6 gene: cDNA sequence, expression analysis, and
            chromosome assignment
  JOURNAL   Cytogenet Cell Genet 95 (3-4), 196-201 (2001)
   PUBMED   12063400
  REMARK    GeneRIF: The mouse Arhgef6 gene: cDNA sequence, expression
            analysis, and X chromosome assignment.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL672106.9 and AL672128.8.
            
            On Apr 20, 2022 this sequence version replaced NM_152801.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF393831.1, SRR13422601.821109.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-229               AL672106.9         53048-53276         c
            230-313             AL672106.9         51662-51745         c
            314-398             AL672106.9         19276-19360         c
            399-520             AL672106.9         17020-17141         c
            521-722             AL672106.9         14170-14371         c
            723-793             AL672106.9         3931-4001           c
            794-888             AL672128.8         206859-206953       c
            889-984             AL672128.8         202525-202620       c
            985-1107            AL672128.8         200542-200664       c
            1108-1246           AL672128.8         182768-182906       c
            1247-1306           AL672128.8         177937-177996       c
            1307-1453           AL672128.8         175610-175756       c
            1454-1540           AL672128.8         173034-173120       c
            1541-1619           AL672128.8         172199-172277       c
            1620-1765           AL672128.8         171252-171397       c
            1766-1891           AL672128.8         170037-170162       c
            1892-1912           AL672128.8         168453-168473       c
            1913-2006           AL672128.8         167241-167334       c
            2007-2084           AL672128.8         165813-165890       c
            2085-2184           AL672128.8         163633-163732       c
            2185-2239           AL672128.8         161504-161558       c
            2240-4406           AL672128.8         158132-160298       c
FEATURES             Location/Qualifiers
     source          1..4406
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 31.26 cM"
     gene            1..4406
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /note="Rac/Cdc42 guanine nucleotide exchange factor 6"
                     /db_xref="GeneID:73341"
                     /db_xref="MGI:MGI:1920591"
     exon            1..229
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..2380
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Rac/Cdc42 guanine exchange factor (GEF) 6; rho guanine
                     nucleotide exchange factor 6; alpha PIX Rho GTPase guanine
                     nucleotide exchange factor; Rac/Cdc42 guanine nucleotide
                     exchange factor (GEF) 6"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 6 isoform
                     1"
                     /protein_id="NP_690014.3"
                     /db_xref="CCDS:CCDS40984.2"
                     /db_xref="GeneID:73341"
                     /db_xref="MGI:MGI:1920591"
                     /translation="MNPEERLVTWLISLGVLESPKKTVCDPEEFLKSSLKNGVVLCKL
                     INRLLPGSVEKYCLEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNT
                     LLAVNKATEDQLSERPCGRSSSLSAATSSQTNPQVAVPSTAPEQHSEEKAEMTENGSH
                     QLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKP
                     SERPLSPKAIKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNL
                     STVEFTCLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLNLMPHFKSMYLAYC
                     ANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERH
                     MEDTHPDHQDILKAIIAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVI
                     FMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKIPIAGMVVNRLDEI
                     EGSDCMFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPTSCGSLSKTSSSSCSTH
                     SSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKT
                     MKKFLHKRKTERKASEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQ
                     VLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKS
                     RKDLEKLVRKLLKQTDECIRSESSSKTSILQ"
     exon            230..313
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            314..398
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            399..520
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            521..722
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            723..793
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            794..888
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            889..984
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1107
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1246
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1306
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            1307..1453
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1540
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1619
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            1620..1765
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            1766..1891
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..1912
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            1913..2006
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            2007..2084
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            2085..2184
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2239
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     exon            2240..4406
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4384..4389
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /note="hexamer: AATAAA"
     polyA_site      4406
                     /gene="Arhgef6"
                     /gene_synonym="1600028C08Rik; 1700038J06Rik;
                     4930592P22Rik; alpha-PIX"
                     /note="major polyA site"
ORIGIN      
        1 acggatgtgg cttagtcttc acagctgccc cgagagctgt tcagagcgtc cgagagcctc
       61 agtcatgaat ccagaagaac gccttgtgac atggcttata tctttgggag ttctagagtc
      121 tcccaaaaag actgtctgtg atccagagga gttcttgaag tcctcgctga aaaatggggt
      181 agtgttgtgc aaactcataa acagacttct gcctggctcg gtggagaagt attgtctgga
      241 accccaaact gaggccgact gcatcgacaa catcaatgac ttcctgaaag gatgtgcaac
      301 tcttcaagtg gaagtgtttg agcctgatga cctctattcg ggggccaatt tctccaaggt
      361 tctgaatact cttttagctg tcaacaaagc aactgaagat cagctctcag aaagaccatg
      421 tggaaggtcc tcttctctta gtgctgcgac cagctctcag acaaacccgc aggtggccgt
      481 tcccagcaca gctccagagc agcacagcga ggaaaaggca gagatgacgg aaaatggaag
      541 tcaccagttg atagtaaagg caagattcaa cttcaagcag acgaatgaag atgaattgtc
      601 agtgtgtaaa ggggacatca tttatgtcac acgagttgaa gaaggaggct ggtgggaagg
      661 cacattaaat gggagaactg gatggttccc tagtaattat gtccgagaaa ttaaacccag
      721 tgagagacct ctgtccccta aggctatcaa aggatttgac actgctccac ttaccaagaa
      781 ttactacact gtggtgttac agaacatctt ggacactgaa aaagaatatg ccaaagaact
      841 tcagtctctt cttgttactt acctaagacc cttgcagtct aataacaacc tgagtactgt
      901 ggagtttaca tgtttattgg gaaactttga agaagtatgc acatttcaac agacactctg
      961 ccaagccttg gaagaatgtt caaagtttcc agaaaaccaa cacaaagtag gaggctgcct
     1021 actgaacctc atgcctcatt tcaaatcgat gtacctggct tactgtgcaa atcatccatc
     1081 agctgtcaac gtgctcaccc agcacagtga tgatctagaa cgattcatgg aaaatcaagg
     1141 tgcatccagc ccgggtatcc tcattctaac aacaagtctc agcaaaccat tcatgcgact
     1201 ggaaaagtat gttactctct tgcaagaact ggaacgacat atggaggaca ctcatccaga
     1261 ccatcaggat attctgaaag caatcatagc attcaaaaca ctcatggggc agtgtcaaga
     1321 tctgagaaag agaaagcagc tggaattgca gatcctttca gaacctattc aggcatggga
     1381 aggagatgat attaagactt tgggaaatgt gatctttatg tctcaagtag tgatgcagca
     1441 tggggcctgt gaggagaaag aggaacgata ttttctgctg ttttcaagtg tcttgataat
     1501 gttgtctgca agtcctcgga tgagtggctt tatgtatcag ggaaaaatac caatagcagg
     1561 gatggtagtg aacagattgg atgaaattga aggcagtgac tgtatgttcg aaatcacagg
     1621 tagcacggtt gagagaattg tggtccattg caacaataac caggacttcc aggagtggat
     1681 ggagcagctg aacagactga ccaaaggacc aacctcttgc ggttcattgt ctaagacctc
     1741 ctcctcatca tgtagtactc attcttcttt tagctctacc ggacagcccc gaggaccctt
     1801 ggagcctcct caaattataa aaccgtggag tttaagttgc ctacgacctg cacctccact
     1861 tagaccatca gcagcactag gttataaaga gaggatgtct tatatcttaa aggaatctag
     1921 taagagcccc aaaacaatga agaagtttct tcacaaaaga aagacggaga ggaaagcatc
     1981 cgaggaagaa tacgtgatta ggaaaagtac tgctgccctg gaagaggatg ctcagattct
     2041 taaggtgatc gaagcttatt gcaccagcgc cagttttcaa caaggtactc gtaaagattc
     2101 tgttccacaa gttctactcc ccgaggaaga gaaactcatt attgaagaaa ccagaagtaa
     2161 tgggcagacc atcattgaag agaagagcct tgttgatact gtctatgcct tgaaggatga
     2221 ggtcaaggaa ctgaagcagg agaataaaaa aatgaagcaa tgtctggaag aagaattgaa
     2281 gtcgaggaag gacctagaga agctggtccg gaagctgttg aaacaaacag atgaatgcat
     2341 tcgatctgaa tccagcagca agacctcgat tctccagtaa ccatcactgt gcagctgagc
     2401 acagtgcctt cagcactcct taaagtggcc agctgaatgg tttcactgtg catttgagct
     2461 ttgtgctttg tggtgttggg atgctctctc tttcttcctc tctcccttcc cctccccctt
     2521 ccccctccac tgtttgattc agagtttatt gcttggttat cagttgattg acacttgttt
     2581 taacaggggg aaatagcctg acgtggtggc caaaatggcc ccaatacttt gctatgccca
     2641 acagcccttt actacctaat tcgctggagg ctaagcttct caggctatgt atagagtagg
     2701 tgaaaatgaa cacctttgcc cagtgaccca gttgcacttc cctttactat catatggccc
     2761 ccttcagtac tttaagaact tattgcccat gttgtctgtt gagatcaaga acagtgtagt
     2821 gcccttatgc cctctgccct ctgtgctgtt gtccatttaa agtcagtgtg gtaggaactc
     2881 caaccatcca caccagcacc aagtctctca gcaaattgct tcaggcagtc ctccgtcagc
     2941 agcagggcaa agcagcttga tggagtactt atccctagta tagcgtagct ttacagccca
     3001 gccctctgcc tctatgtaag ttttctacct cccctcaacc ccatgctttt agccagccat
     3061 acaaagtggg gtgtcaatga tcatggattt gctttgctta tcttgtcagt tactgtgagc
     3121 aatgacttta ctttgaatat tcccatgaca accttttcac ctttctaaac aacttgggtg
     3181 agaaaatatt gtgccctcgt acaccttcca tcccatctca ccaagctctg gtttctgcaa
     3241 tgagaagttg gactcatcag tggcctctag gatgatgatc cagattatag accctgagtt
     3301 aaagggcccc tcctagctgg agcaggctgt cagtgaagct gactatttga aactagtttg
     3361 ttcaagttgt ttataatgtc aaaccattga ctttgtatgt ggtccagaaa agtgacccgt
     3421 gagaaagcag atttcacaga gagccccaga agaacactgt atacctaaat tcaacacaag
     3481 tcaaaatggg ctgaggatgg aggaacacag ctctcaccta cctcctcaga tgacagcaca
     3541 acttggccag atggcaaagt cactggaaaa agatgcagaa agccaaccaa aggcttacgt
     3601 gtatattatt tgattgggcc ctgtaagggt tgtttcaaaa ccaaccttga ggcctaaaag
     3661 cttgttgagg agcccttttc ctttgtgata tggaggctct cacagtttcc ataactttat
     3721 ggtacagtgc tattatctca tgttacatgg ccaacattat agcacccaca ggatgtggag
     3781 tattcctaaa ggccaacctc agacaatcgc atagagctat ctttgtcagc ttagagagta
     3841 aaggttgcta agaacagctg tcctgtttct aagcccagag atttctatga gacatctttc
     3901 atgtaaaaca tttttacaaa aggaataaca gtagcaaccc acatgttccc atttgtcctg
     3961 tctgtgcttg gtcaatagtt ggcaatcaat gtgcaaaatt tgtccatagg aaaaaccact
     4021 tttgtggtcg ccaaataatt tagttcattg cttaagacat tgaaaggtct cataaaggat
     4081 gtgtacatat gcatgtttgg ggactttgcc cttatgagga gaggcccttg gtactctgga
     4141 taaggaaact tgtgcagtgg gctgcccatg cttacacact aaataatata aaggaaatga
     4201 agccatgtta actccacagt catgtctcca tagttgtgtt gtttacaata ctctggaagt
     4261 aaactgctgc ccttaggggc ctttcagttt cccctctgtt atgtcccttc ttataggagc
     4321 tcagattttc taaacttgtt tttattttaa agacttttaa aatggacatt ttcaataaac
     4381 aagaataaac agtgctttat aaataa
//
