LOCUS       NM_198249               5622 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Rho guanine nucleotide exchange factor 40 (Arhgef40),
            transcript variant 1, mRNA.
ACCESSION   NM_198249
VERSION     NM_198249.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5622)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5622)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5622)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   4  (bases 1 to 5622)
  AUTHORS   Tse,S.W., Broderick,J.A., Wei,M.L., Luo,M.H., Smith,D.,
            McCaffery,P., Stamm,S. and Andreadis,A.
  TITLE     Identification, expression analysis, genomic organization and
            cellular location of a novel protein with a RhoGEF domain
  JOURNAL   Gene 359, 63-72 (2005)
   PUBMED   16143467
REFERENCE   5  (bases 1 to 5622)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK163945.1 and AK143527.1.
            
            On Mar 21, 2009 this sequence version replaced NM_198249.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and it encodes the longest protein (isoform 1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143527.1, SRR7974084.27850.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AK163945.1         2-27
            27-5622             AK143527.1         2-5597
FEATURES             Location/Qualifiers
     source          1..5622
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 26.75 cM"
     gene            1..5622
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /note="Rho guanine nucleotide exchange factor 40"
                     /db_xref="GeneID:268739"
                     /db_xref="MGI:MGI:2685515"
     exon            1..159
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     CDS             157..4710
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein SOLO; Rho guanine nucleotide exchange factor (GEF)
                     40"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 40
                     isoform 1"
                     /protein_id="NP_937892.2"
                     /db_xref="CCDS:CCDS49488.1"
                     /db_xref="GeneID:268739"
                     /db_xref="MGI:MGI:2685515"
                     /translation="MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDA
                     LRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRP
                     GDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPSEACAYLFTPEWLQGINKDRPTG
                     RLSTCLLSAPSGIQRLPWAELVCPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLP
                     EEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPVRGSPVDAEASGLSRTRTVPARKST
                     GGKGRHRRHRAWMNQKGLGSRDQDGTRPPGEGSSTGASSDSPSGAEADPDATALQASE
                     PPAEALGEAPESCLLSGEAVGGVGQGAEGPPGTPRRTGKGNRRKKRAAGRGAGSRGGE
                     GTSLSPRDKEETRQQEVLVSLPSPSEQEPAECSLVKEKEDSGKQESESKEELKPADEK
                     EPARPEDYEPPEEEIRESEKEELTPQCTAGSTGPEWFPSEPSTQPLETVQNVKGDSLP
                     EETPPVSVLDDPVVAWDLMASGFFVLTGGVDQTGRALLTITPPPPCLPEESSPSQETL
                     STALRYLHSLLRPDLQLLGLTILLDLRKAPPLPPALLPALSQLQDSGEPPLIQRLVIL
                     IHEDPPAELCGFQGAELLSEKDLKRVAKPEELQWDLGGHRDLSPNHWAEIHQEVARLC
                     TLCQGVLTSVRQAIEELEGTAEPKEEEAVGMPEPLQKVLADPRLTALQRNGGAILMRL
                     RSAHSSKLEGPGPAELYQEVDEAIHQLVRLSNLRVQQQEERQRLRQVQQVLQWLSGPG
                     EEQLASFSMPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEEDLTSQKVLDIFE
                     QRLEQAESGLHRALRLQRFFQQAHEWVDEGSARLAGAGSGREALLAALALRRAPEPSA
                     GTFQEMRALALDLGSPAALREWGRCRARCQELERRIQQQLGEEASPRSHRRRRADSAS
                     SAGAQHGAHSPSPSLSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLELAPETDGRPP
                     RAVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRSISAQQRLV
                     SELIACEQEYVTTLNEPVPLPGPELTPELRCTWAAALSVRERLRSFHGTHFLQELQGC
                     AAHPLRIGACFLRHGDQFNLYAQFVKHRHKLESGLAALTPSVKGSMESSPCLPRALQQ
                     PLEQLARYGQLLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEI
                     DLKEQGQLLHRDPFTVICGRKKCLRHVFLFEDLLLFSKLKGSEGGSETFVYKQAFKTA
                     DMGLTENIGDSGLCFELWFRRRRAREAYTLQATSPETKLKWTSSIAQLLWRQAAHNKE
                     LRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLS
                     PGACSLPARVEEEAWDLDVKQISLASETLDSSGDVSPGPRNSPSLQPPSPGSSTPALT
                     SGGILGLSRQSHSRALSDPTTPL"
     exon            160..357
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            358..1594
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..1762
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1889
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..1986
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            1987..2067
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            2068..2184
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2280
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            2281..2396
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            2397..2523
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            2524..2646
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            2647..2790
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            2791..3401
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            3402..3636
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            3637..3723
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            3724..3939
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            3940..4110
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            4111..4288
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            4289..4393
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            4394..4537
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            4538..4668
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            4669..4715
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     exon            4716..5622
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4979..4984
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /note="hexamer: ATTAAA"
     regulatory      4983..4988
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /note="hexamer: AATATA"
     polyA_site      4998
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /note="major polyA site"
     polyA_site      5032
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
     regulatory      5599..5604
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
                     /note="hexamer: AATAAA"
     polyA_site      5620
                     /gene="Arhgef40"
                     /gene_synonym="E130112L23Rik; Gm669; Solo"
ORIGIN      
        1 cccgcggcct gggctgccga acgagcgggg agagccgcgg tcgccgcgcg agttgtcctg
       61 cagctagacc cggcgagact gagcgcccgg agggaggcgg tggctcaccc gccccgcccg
      121 cccgccggag agtgggacac ctcccgacgc cgagccatgg agcctgaacc agtggaggac
      181 tgtgtgcaga gcacgcttgc tgccttgtac ccgccctttg aagccacagc cccaaccctg
      241 ttgggccagg tgttccaggt ggtggagagg acgtaccagg aggatgcgct gaggtacacg
      301 ctggacttcc tggtacctgc taaacacctg cttgccaagg tccagcagga agcctgtgcc
      361 cagtatagtg gattcctctt cttccacgag ggctggccac tctgcttgca tgagcaggtg
      421 gtagtgcagc tagcggccct tccctggcag ctgctgcgcc ctggagactt ctacctgcag
      481 gtagtgcctt cagcagccca ggcaccccgg ctggcactga aatgcctggc cccaggaggt
      541 gggcgggtac aggagctccc agtgcccagt gaagcctgtg cctacctctt cacacctgag
      601 tggctacaag gcattaacaa ggaccggcca acagggcgcc tcagcacctg ccttctgtcc
      661 gccccctccg ggatccagcg gctgccctgg gctgagctcg tctgcccacg atttgtgcac
      721 aaagagggcc tcatggtggg acatcaacca agtacattgc ctccagaact gccctctgga
      781 cctccaggtc ttcccagctc tccactccct gaggaggtac ttggtacccg gagtcctggg
      841 gatggacaca acgctcccgc agaaggtccc gagggtgaat atgtggagct gttggaggtg
      901 acactgcctg tgaggggaag ccctgtagat gctgaggcct cgggcctctc ccggacccgc
      961 acagtacccg cccgtaagag cactggaggg aagggccggc accggagaca cagggcgtgg
     1021 atgaatcaga aaggcctggg atctcgggat caggatggga cgcggccgcc tggtgaggga
     1081 agtagcaccg gggcctcttc cgactcacct tcaggggctg aggcagaccc agatgccacc
     1141 gccctccagg catctgagcc cccggcagag gctctcgggg aagcccctga atcctgcctc
     1201 ctgtcagggg aggctgtggg aggagtgggc cagggggctg aaggaccacc tggtacccct
     1261 cgaagaaccg gcaaaggaaa cagaagaaag aagcgagctg cgggcagagg cgctggaagc
     1321 cggggagggg agggtacctc actcagcccc agggacaaag aagagaccag acagcaggaa
     1381 gtccttgtca gtctgccctc acccagtgaa caggaacctg cagaatgcag cctggttaag
     1441 gagaaagagg attctgggaa gcaagagtct gaatcaaaag aggaactcaa gccagcagat
     1501 gaaaaagagc ctgcacgccc agaagactat gagcctccag aagaggagat cagagagagt
     1561 gagaaagagg agttgacccc gcagtgtacg gcaggatcca caggtccaga gtggttccca
     1621 tctgagccct caacacagcc cctggagact gtgcagaatg ttaaaggaga cagcctccca
     1681 gaggaaactc ccccagtttc tgttttggat gacccagttg tagcttggga cttgatggca
     1741 tctggattct tcgttctgac tggaggggta gatcagactg ggcgagctct gctgacaatc
     1801 acgcctccac ctccgtgcct tcctgaggag tcctcaccct cccaagagac actgagcact
     1861 gctctccgtt acctccactc actgcttagg cctgatctgc agttactggg gctgaccatc
     1921 ctccttgacc ttcgcaaggc acctccactg cctccagcac ttcttcctgc cttgagtcag
     1981 cttcaggact caggcgagcc tccgctcatt cagcggctgg tgatcctcat tcatgaagac
     2041 cctccagctg aactctgtgg atttcaggga gctgagttgc tgtcagagaa ggatctgaaa
     2101 agagtggcca agccagagga gctacagtgg gacttaggag gtcacaggga cctctccccc
     2161 aaccactggg cagagataca tcaggaagtg gcaaggctat gcaccttgtg ccaaggcgtg
     2221 ttgacctccg tacggcaggc cattgaggag ctagagggaa cagcagaacc caaagaagag
     2281 gaggccgtgg gaatgcctga gcctctgcaa aaggtgctgg cagatcctcg gctgacagca
     2341 ctacagagga acggaggagc catcctgatg cgcctgcgct ccgcccacag cagcaagcta
     2401 gagggcccag gcccagctga gctataccag gaggtagatg aggccattca ccaacttgtg
     2461 cgtctgtcca acctacgagt gcagcagcag gaagaacggc agcgcctgcg ccaagtccag
     2521 caggtgttgc agtggctgtc tggcccagga gaagagcagc tggcaagctt ctccatgccg
     2581 gggaactcac tgtcagtctt gcaagagaca gaacttcgat tcagggcttt tagcacagaa
     2641 gtgcaggagc gcctagtcca agcccgggaa gctttggctc tggaggagga ccttacctcc
     2701 cagaaagttc tagacatctt tgaacaacgg ttggagcagg ctgagagcgg cctccaccgg
     2761 gccctcaggc tacagcgctt cttccagcag gcacacgaat gggtagatga gggctctgct
     2821 cggctggcag gagctgggtc tggtcgtgaa gctctgctgg cagccctagc cctgcggagg
     2881 gccccagaac ccagtgcagg caccttccaa gagatgcgag ccctggccct ggacttgggc
     2941 agccccgcag cccttcgaga gtggggccga tgtcgggcac gctgccagga gctggaaaga
     3001 aggattcagc agcagctggg agaggaggcc agtcctagaa gccaccgacg acgtcgggca
     3061 gacagtgcca gcagcgcagg ggcccagcac ggagcccata gcccttcacc cagcctcagt
     3121 tccctgctgc ttcccagcag ccctgggcca cgggcagccc catcacattg ctctctgacc
     3181 ccatgtgggg aggattatga ggaagaaggc cttgagctag ctccagaaac agatggaaga
     3241 cccccaaggg ctgtgctaat ccgaggactg gaggtcacca gtactgaagt ggtagacagg
     3301 acatgttcgc cccgagaaca cgtactattg ggccgggctg gagggccaga tggaccctgg
     3361 ggaataggta cccctcgaat ggaacgcaaa cgaagcatca gcgcccagca gcgtctagtg
     3421 tctgaactga ttgcctgtga gcaggagtac gtaaccaccc tgaatgagcc agtgccgctg
     3481 cctgggcctg agctaacgcc tgagcttcga tgcacctggg ctgcagccct gagtgtccga
     3541 gagaggcttc gcagcttcca cgggacacac tttctacaag agcttcaggg ctgcgccgcc
     3601 caccccctgc gcattggggc ctgcttcctt cgccatgggg atcagttcaa cctctatgca
     3661 cagttcgtga agcacaggca taaactggag agtggtctgg ctgcgctcac cccctcggtc
     3721 aagggttcca tggagagcag cccttgcttg ccccgggccc tgcagcagcc actggagcag
     3781 ctggctcggt atggacagct cctggaggag ctcctgaggg aagccgggcc tgagctaagc
     3841 tctgaacgcc aggccctcag ggccgctgta cagttgctcc aggaacaaga ggcccgaggc
     3901 agagatctgc ttgctgtgga agctgttcga ggctgtgaga tagatctaaa ggaacaggga
     3961 cagctcttgc atcgggaccc tttcactgtc atctgtggcc ggaaaaagtg cctccgccac
     4021 gtcttcctgt ttgaggacct gctcttattc agcaagctca agggatctga aggaggatcc
     4081 gagaccttcg tttacaagca ggctttcaag accgctgaca tggggctgac agaaaacatc
     4141 ggggacagtg gactctgttt cgaactatgg tttcgacgac ggcgtgcaag agaagcatac
     4201 acgttgcagg ctacttcgcc agagaccaaa ctcaagtgga caagttctat tgcccagctg
     4261 ctgtggagac aggcagccca caacaaggaa ctccgagtgc agcagatggt ttccatgggc
     4321 attgggaata aacctttcct ggacattaaa gcccttgggg aacggacact gagtgccctg
     4381 ctcactggaa gagccgcccg cacccgggcc tccgtagcgg tgtcatcctt tgaacatgct
     4441 ggcccgtccc ttcccggcct ctcaccggga gcctgctccc tgcctgcccg cgtcgaggag
     4501 gaggcctggg atctggacgt caagcagatt tccctggcct cagaaacact tgattcttct
     4561 ggagatgtgt ccccaggacc acgaaacagc cccagcctgc agccccccag ccctgggagc
     4621 agtactcccg ctctgaccag tggagggatc ttagggctct ctcggcagag tcattcccga
     4681 gccctgagtg accccaccac gcctctgtga gctaggaacc ggagtggccc tgttcaattg
     4741 cctttatgct ccgagggcag ggaaatgtcc ccttgctgtg ctactgcaca cccccgggac
     4801 actgctctgc ggacacccac tactcttctc atcccaactc tcccagaaga ttcatctctg
     4861 ccaggtcgaa tggaattcca ttctgggaga tcatgagaaa tatgttgtaa gccactgaag
     4921 gagacggggt gggcactgca gactttatat gtaattactg ttattatact attgttacat
     4981 taaatatatt tactctcact gtgactctga ggagctcgcg caggcctctg gattaaggtg
     5041 gttgaactga cttcattact tccctataac cactaagtag gactcagaag ataaaaccaa
     5101 ggtcagaaag tagctgttcc ttcctcccct tgctggcccc aacactgcag gtctgggtct
     5161 gagtgtggga gaatgcctcc ccctcaggct ctgggaagct caatgaactc tgaagtccct
     5221 cctccattct gcacccactt cttgaggcct gagatggtcg gatgggtcca gcacaatgca
     5281 gcacttatct atgatgtcct cgggcctcag tgcaagagag gccacggcta tttattacaa
     5341 acgctagctt tagggcctca tccagagtta ctgaatcaaa gatttgcatc cttatcgacc
     5401 tcgttgataa cgaagtgccc aggaggagtg aaacacaggc agacacacac agggccttgt
     5461 gcctcaagac acctgtttat tggggacatg actcttcaac agggatgaca ggaatcgtac
     5521 caaaaatagc aacgtctaca agggcccctg atagggctag aagggtacag tgccccccac
     5581 ccccacccct tatacaaaaa taaactctca tgcctatgga cc
//
