LOCUS       NM_177828               3234 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus Rho guanine nucleotide exchange factor 37 (Arhgef37),
            mRNA.
ACCESSION   NM_177828
VERSION     NM_177828.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3234)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ045695.1, CJ131942.1, AK177275.1, AK030242.1 and AC153155.6.
            
            On Nov 15, 2007 this sequence version replaced NM_177828.3.
            
            ##Evidence-Data-START##
            CDS exon combination :: AB199795.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMN00849374,
                                    SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-207               CJ045695.1         1-207
            208-607             CJ131942.1         109-508
            608-627             AK177275.1         221-240
            628-2228            AK030242.1         455-2055
            2229-3234           AC153155.6         105997-107002       c
FEATURES             Location/Qualifiers
     source          1..3234
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 34.62 cM"
     gene            1..3234
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /note="Rho guanine nucleotide exchange factor 37"
                     /db_xref="GeneID:328967"
                     /db_xref="MGI:MGI:3045339"
     exon            1..146
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            147..343
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             158..2188
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /note="probable guanine nucleotide exchange factor
                     FLJ41603 homolog; Rho guanine nucleotide exchange factor
                     (GEF) 37"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 37"
                     /protein_id="NP_808496.2"
                     /db_xref="CCDS:CCDS50302.1"
                     /db_xref="GeneID:328967"
                     /db_xref="MGI:MGI:3045339"
                     /translation="MADFGADEASSKSESPEQEDQGSEDRSLLHQRLAIRELIDTEVS
                     YLHMLRLCASDIRSHLQQLPPGDLDILFSNIDDIIQVSSRFLRGLQETACREEEQAHL
                     IGNLFLEFQEEFEQVYKVYCANYDQALLLVKAYQKEPELQKEIQGIIEAAMPQAGPSG
                     LSFFLVIPLQRITKYPLLLQKILENTPADASAHPALQRATSALQDVNGNINEYKMRKE
                     VALKYTKVEQLSLRERLARINTHTLSKKTTRLSQMLKQEAGLVSRTEDKEFDDLEERF
                     QWVSLCVKELRNNVVDFMGNLEVFLSFRPHERSLDIPGGPAEQYCSLARDLQLHAFLQ
                     FKQRLRSLVWQPLCSLARALAGPQNLIKKRLDKLLDFDRVEEKLLDVGSVTWEEEAAR
                     HEYQALNSLLVAELPQFNQLVMQWLGQILCTFVVLQRDLADQVLRRAESTMALLPHHH
                     VSEPDFQKLLEHTLGQSSSQLRLFQESFEKVLPPSTTQPLLPGSEHQMQALLTRYGPE
                     KLYQVSSNINGTGTLDLTLLRGQIVALLQNKDTKGNNSRWLVDTGGHRGYVPAGKLQL
                     YHPIIPSEKELRGQTGTHEDSWLPAPEPTQLSVPTVPTMSQVVAVYPFVARSTHELSL
                     QAGQPVTILEAQDKKGNPEWSLVEANGQRGYVPSNFLARTPSPTPWGWNLPS"
     exon            344..467
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            468..615
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            616..815
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            816..946
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            947..1051
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1162
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1492
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1621
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1622..1817
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1818..1978
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1979..3234
                     /gene="Arhgef37"
                     /gene_synonym="4933429F08Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagcttccc agagccgggc agctggagcc cagcgggtgc aagtgactcc ggagggcatc
       61 cggcgcgtgc gcggtgagtc cagcccggcg acggcgacag gatgccgcca ggagggctgc
      121 ggggaaacag ctgctggaca gatgagaacc tgtggacatg gctgactttg gagcagatga
      181 ggcctcttcc aagtcagaga gtcctgagca ggaagatcag ggctctgagg acagatcgct
      241 gctccatcag aggctggcca tcagagagct cattgacaca gaagtctcct acttacacat
      301 gctccgactc tgtgcctctg acatcagaag ccacctacaa cagctgccac caggcgatct
      361 ggacatcctg ttctccaaca tcgatgacat catccaagtg agcagcaggt tccttcgagg
      421 gctgcaggag acagcctgca gggaagagga gcaagcgcac ctgattggta acttattctt
      481 ggaattccaa gaggagtttg aacaagtcta taaagtctac tgtgccaact atgaccaggc
      541 cctgctgctg gtcaaggcgt accagaagga gccagaactg cagaaggaga tccagggcat
      601 catcgaagct gccatgccac aagctggacc ttcgggtctc agtttcttcc ttgtgatccc
      661 tctacagagg attaccaagt accccctcct gctgcagaaa attctggaga acacacctgc
      721 agatgccagc gcccaccctg cccttcagag agccacctct gccctccagg atgtgaacgg
      781 caatatcaac gaatacaaga tgcgcaagga agtggcctta aagtatacca aagtggagca
      841 gctgagcctt cgggagcggc tggcccgcat caacacacat actctttcca agaagaccac
      901 cagactgagc cagatgctga agcaggaggc ggggcttgta tcccggacag aagacaagga
      961 atttgatgac ctggaggaga gattccagtg ggtgtctctg tgtgtgaagg agctcagaaa
     1021 caatgtggtc gatttcatgg gtaatctgga ggttttcctc agcttccggc cacacgaacg
     1081 gagcctggat atccctgggg gacctgcgga gcagtactgc agcctagcga gggaccttca
     1141 gctccatgcc tttctgcagt ttaagcagcg gttaagaagc ctggtgtggc aaccattgtg
     1201 cagtctggcc agagccctgg ctggtcctca gaacttgatc aagaagcgcc tggacaaact
     1261 cctggacttc gatcgagtag aggagaagct gttagatgtg ggcagcgtga cctgggagga
     1321 ggaggcagcc cggcacgaat accaggcgct caactcctta ctagtggccg agctcccaca
     1381 gtttaaccaa ctcgtcatgc agtggctggg tcagatcctg tgcacatttg tggtcctcca
     1441 gagagacctc gccgatcaag tgctacgaag ggcagagagc accatggctc tgctgcctca
     1501 tcaccacgtc tcagagccgg acttccagaa gctgctggag cacacactag gccagagcag
     1561 cagtcagctc cgcctctttc aggagagctt tgagaaggtg cttccaccct ccaccactca
     1621 gccactcctt ccagggtctg aacaccagat gcaggctctc cttaccagat atggccctga
     1681 gaagctatac caggtgtcaa gcaacatcaa cgggactggg actctggacc tgaccctgct
     1741 gcggggccaa atcgtggccc ttctacaaaa caaggatacc aaaggcaaca acagtcgctg
     1801 gctggtagac acagggggac accggggcta tgtgccagct ggaaaacttc agttatacca
     1861 ccccatcatt cccagtgaga aggagctcag aggccagaca gggacacatg aagactcctg
     1921 gcttccagcc ccagagccca cccagctctc tgttcccact gtcccaacca tgagtcaggt
     1981 ggtggcagta tacccttttg tggccagaag cacccacgaa ctgagtctac aggcaggcca
     2041 gcctgtgacc atcctagagg cccaagacaa gaaggggaac ccagaatgga gcctggtgga
     2101 agcaaacgga cagaggggct atgtgccttc caactttcta gccaggaccc caagcccaac
     2161 tccctggggc tggaatcttc cctcttaaga tgccctcttt ggaaccccca ttcctatgga
     2221 cttaaaaggt gtctgaccta ggggacatgg cacaaagcac agtgggaatg ggatcggtgt
     2281 gaagggcacc cagaagttag caggaagtgg tgactaggcc ttacagaatg cctagtgtgg
     2341 gaggccacag tgggtggctc agcagtgcca ctcttgtctg cataaagaag ccatctcaag
     2401 gccacagctg attagctagg gcttgccaca gctcgaagct catcctacct ctttcctctc
     2461 tcatgtttag gatgaatgtt gcttgtgtta gtcgcaggca gggcatctct gaagaagacc
     2521 agacctgtct ggcttgatag tacacttccc ccagcgttgc caggaaacac cacggctcac
     2581 tactcatctt ttctttcttg ctgctttgag ttactgtgaa cagtgaactg tgaagagtcc
     2641 tgctcaaggg gaagccatgg gcctaggttc tgaggagatc ctctactggg tctgggaatg
     2701 ggtgtggtct ctgcacaggt ctggactgtg tgtacaaact cggaggcggt tccagggaag
     2761 aggggaattt gagggtggat cagtgggtgt gtgaggctga ttgcaatggt ctagactcgt
     2821 ggtgttttct tcagactagg agacaaagga acttggcagt caatgctggt ggagctctgt
     2881 gagacaggtg actactggcc tggcgctctg ggtaggtgaa ggatggtgtg atttcctggt
     2941 tctgggtaga agaaccagag aacacaggtg gcctgggttt gcctctgagg ccatggaggc
     3001 tgcagggagc tgaggttggg tagatgtgag gcccaagacg taggacacaa ctgcactttt
     3061 ccacctagga aaataaccaa gtcgtgggat gtggtaagaa tgtatgtcat gaggctgagg
     3121 atccttgtca accaggaagc gtgacactaa caaaaagact gttagtggcg tcgggatggc
     3181 gcagccattg gctggcttgg gttagcagag taaagcagtc ctgtgccacc cctc
//
