LOCUS       XM_017312501            5398 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus Rho/Rac guanine nucleotide exchange factor
            18 (Arhgef18), transcript variant X5, mRNA.
ACCESSION   XM_017312501
VERSION     XM_017312501.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000074.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_017312501.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5398
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="8"
     gene            1..5398
                     /gene="Arhgef18"
                     /gene_synonym="A430078G23Rik; D030053O22Rik"
                     /note="Rho/Rac guanine nucleotide exchange factor 18;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 17 ESTs, 107 long SRA reads, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 21 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:102098"
                     /db_xref="MGI:MGI:2142567"
     CDS             243..3332
                     /gene="Arhgef18"
                     /gene_synonym="A430078G23Rik; D030053O22Rik"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 18
                     isoform X4"
                     /protein_id="XP_017167990.1"
                     /db_xref="GeneID:102098"
                     /db_xref="MGI:MGI:2142567"
                     /translation="MTISQKGGLQPTPSPAGSGVRLGPIAGDMDEADSVFLKLKQTAD
                     DSLSLTSSNAESVFIEDPYIASLRCEIESDAHEFEAESWSLSVDLAYAKKQKKEVVKR
                     QDVLYELMQTEAHHVRTLKIMLKVYSRALQEELQFSGQAVSRLFPCADDLLDMHSHFL
                     ARLKERRQEFLEEGSDRNYVIQKIGDVLVQQFSGETGERMKEKYAVFCSGHNDAVGQY
                     KLLLQQSKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTE
                     DYKDLSQALSLIKDIISQVDAKVSEYEKDQRLKEIAAKTDQKSSGKLKNGLTFRKEDM
                     LQQRQLHLEGALCWKSTSGRLKDVLAVLLTDVLLLLQEKDQKYVFASVDSKPPVISLQ
                     KLIVREVANEEKAMFLISASMQGPEMYEMYTSSKEDRNIWMAHIRRAVESCPDEEEDV
                     FSEAEEKKIAEARTMKLQEFQERLSLKDQLIAQSLLEKQQIYLEMAQLSGLEESAQNR
                     GLFRGGGDPSETLRGEQILRSAMSEIEGIQSLICQRHLGSTSSQVEEGSVSAGLPRRA
                     ETFGGYDSVGSPSKGGSFKRKVSNSDLRPQDWQGPASSPDSRPCDNSAPSGCCEESPQ
                     AVEMPSTESLPTVLELETNLAFSLQLVHRVQTLSQLLLSLQAVIAQQDSYVEMQRTAI
                     QEREKQFRLQSTRGNLLLEQERQRNFEKQREERAGVEKLQSQLRQEQQRWERERARQQ
                     QELELAGARLQEREGEARQMRQRLDQERTELERQRQAYQHDLERLREAQRAVDRERER
                     LELLRRFKKQNTVPGALPPEVLAEAQPASHPPSFNGDGLEGHSAPAKAPGTQGSAMLH
                     GTGPDNVERPEVARWDSAPPESRPAKSDVPIQLLSATNQIQRQTAVQQQIPTKLAAST
                     KGGKEKGSKSRGSQRWESSASFDLKQQLLLSKFIGKDESASRNRRSLSPVLPAAHGSA
                     PASDPCFPAPSPAPAATPPEAFKFGGTSLPPVSPASSLPTTPLATTDEVSKEDVIFF"
ORIGIN      
        1 aggaggccgg gcggagactg cgagagcgac ccgggagcca gcagggcgga gagcggcctg
       61 tgagggaccc cgcggagcat gaaagcagaa tctgttcaac tttggatcag accttagttc
      121 aggaactagc tagccatgct aagaggccca gcagaggccg ccattcagcc tccctgaagg
      181 agcaccctcg gaccacactt ctgtctgatg gcagcagccc agctccttcc aggaatgtcg
      241 gcatgaccat ctctcagaaa gggggtctcc agccaacacc gagcccagct ggatctgggg
      301 tgcgacttgg accaattgct ggagacatgg atgaagctga ctccgtgttt ttaaagttga
      361 agcagacggc agacgactct ctgtcactca catcctcgaa tgctgagtct gttttcatag
      421 aagaccctta cattgcttca ctgaggtgtg agatcgaatc agatgcacat gagtttgagg
      481 ccgagtcctg gagcctctct gtggatttag catatgccaa gaaacagaag aaggaggtgg
      541 taaagagaca ggacgtccta tatgagctga tgcagacaga ggctcatcac gtgcgcacac
      601 taaagatcat gctgaaagta tactccagag ccctgcagga agagctgcaa ttcagtggcc
      661 aggcagtcag ccgtctgttt ccgtgcgctg atgacttact ggacatgcac agccatttcc
      721 ttgcccgcct taaggagcgc cggcaggagt tcctagagga gggcagtgat cggaattacg
      781 tcatccaaaa gatcggagac gtcctggttc agcagttctc aggagaaacc ggggagagaa
      841 tgaaggagaa atacgctgtg ttctgtagtg gccacaatga tgcagtcggt cagtacaagc
      901 tattgctgca gcaaagcaag aagtttcaaa acttaatcaa gaaaattggc aacttttcca
      961 ttgtgcgaag gctgggagtg caggagtgca tccttctggt cacacagcgc ataaccaagt
     1021 acccggtgct tgtggaacgc atcatccaga acacagaagc tggcactgag gactacaagg
     1081 acctgagcca agccctgagc ctcatcaaag acatcatctc acaagtggac gccaaagtca
     1141 gtgagtatga gaaggaccag cgcctcaagg agattgcagc caagacggac cagaagtcgt
     1201 ctggcaaact caaaaacggg ctaaccttcc gaaaggagga catgctgcag cagcgccagc
     1261 tccacctgga aggcgccctc tgctggaagt ccacctcagg gcgcctgaaa gatgtcctcg
     1321 ctgtcctgct gaccgatgtg cttttgctgc tgcaagaaaa agatcagaaa tatgtctttg
     1381 cttctgtgga ctcaaagcca cccgtcatct ctctgcaaaa gctcatcgtg agagaggtag
     1441 ccaacgagga gaaggccatg ttcctgatca gcgcctccat gcaggggcca gagatgtatg
     1501 agatgtacac cagctccaaa gaggacagga acatctggat ggcccacatc cgccgggccg
     1561 tggagagctg tcctgacgag gaggaggacg ttttcagtga ggctgaggag aaaaagatag
     1621 ctgaagcccg caccatgaaa ctccaggaat ttcaagagcg actgagcctg aaagaccagc
     1681 tgattgccca gagccttctg gagaaacagc agatctacct ggagatggct cagctgagtg
     1741 ggctggaaga gtcagcccag aaccgaggcc tcttccgagg aggaggagac ccctctgaga
     1801 ccctgcgggg ggagcagatt ctcagatcgg ccatgagtga gattgagggc atccagagcc
     1861 tgatctgcca gcggcacctg ggcagcacca gtagccaagt ggaggaggga agtgtctctg
     1921 caggcctgcc tcggcgggct gagaccttcg ggggctatga cagtgtggga agccctagca
     1981 agggtggcag ctttaaaagg aaggtatcca acagtgacct caggccccaa gactggcagg
     2041 gacctgctag cagcccagac tccaggccct gtgacaacag cgcccccagt ggctgctgtg
     2101 aggaatcgcc acaggctgtg gagatgccta gcacagagag cctgcccact gtcctggaat
     2161 tagagaccaa tttggctttc tctctgcagc tggtccaccg ggtccagaca ctgtcgcagt
     2221 tgcttcttag tctccaggcg gtcatcgctc aacaggatag ctatgtggag atgcaaagaa
     2281 cggccatcca ggagcgcgag aagcagttcc ggctgcagtc aacacgtggg aacctgctgc
     2341 tggagcaaga gcggcaacgc aactttgaga agcagcgtga ggagcgcgcc ggtgtggaga
     2401 agctgcaaag ccaacttcgc caggagcagc agcgatggga gcgggagcgg gcacgccagc
     2461 agcaggaact ggagctggcc ggtgcgcgac tgcaggagcg agagggcgag gcacgccaga
     2521 tgcgccagcg gctggaccag gagcgcaccg agctagagcg acagcgccag gcctaccagc
     2581 atgacctgga gcgtctgcgt gaggcccagc gagcagtgga ccgtgaacgt gagcgcctgg
     2641 agctgctgcg caggttcaag aaacagaaca ctgtaccagg ggcactgccc ccggaggtgc
     2701 tggcagaggc ccaacctgca agccaccctc ccagcttcaa tggcgatggg ctggaggggc
     2761 actcggcccc agccaaagca ccaggaaccc aagggagcgc gatgctacat ggcacaggac
     2821 ctgacaacgt agagcgaccc gaggtggccc gctgggacag tgccccccct gagagccggc
     2881 cagccaagag cgatgtgccc atccagctac tcagtgccac caatcagatt cagaggcaga
     2941 cagccgtgca acagcagatc cccaccaagc tggccgcctc caccaagggt ggcaaggaga
     3001 agggcagcaa gagcaggggt tcccagcgtt gggagagctc agcgtccttc gacctgaagc
     3061 agcagctgct cctcagcaag ttcataggca aggatgagag tgcatcacgg aaccgccgtt
     3121 cactgagtcc cgtcctgcct gccgcccatg ggtctgcacc tgcctcagac ccctgcttcc
     3181 cagccccaag cccggcccca gctgccacac cccccgaggc cttcaagttc ggaggcacat
     3241 cactaccacc tgtctcccca gcttcctcgc tgccaaccac accactcgcc accacagatg
     3301 aagttagtaa ggaagatgtc atcttcttct gaggggccat ggccccaagg gcagacccct
     3361 ttctgtcctg atacccttta tgtctctggg gatcctatgg gtgactgtac tgtctggccg
     3421 tccccttccc ctgcacaagc acagccaggc acttgttccc ttgagattgc ccaaatggta
     3481 tgccttgagt ctcacagctc gctatagatt tagtggcaaa acatgggtag cccccttgaa
     3541 cacacataca tacatgcata tatatgtata tgtgtgtgtg tatatatata tatattatat
     3601 atatatgtat gtgtatatat gctcaaagtt cttttaagtt gaaggtggaa ccccccagag
     3661 gtataaagcc caagacttgg gagccagcca ggagacagag cagggcaggc aggtctgaga
     3721 agataccggc tccaggggca gactccataa cccccaggaa tctctgaatt aaactgagtc
     3781 attttgcacc agaaggcact agaatcaccc agagtccagc gaatctccac ttccaaagca
     3841 gcaactggca ctggccacag ccttgaccag aaaatggcct gggcaactcc agaggataca
     3901 gaaagactca ggcagccccg ggcaatccat ggagcaatgg actggatctg cgggttcaga
     3961 aatcaatctg atgaggggtt accaactgtc actccttgca gtaggctggg gtcttcccaa
     4021 ctctgcttct cagggggcac ctgccatgtc cgcccatcca ccttacctgg gatgcagaac
     4081 cccagtttca gcagggcagc acagaccgtg tttgatcgct gtgaaatgag cagatttttc
     4141 ctggtcctgt cagtgttctc acagaaaagc agagctaaca cattcaggga catgtggagg
     4201 aatagcctag tgacattgcc ggtgagtagc cacagatggc catcttggta ccacctcagc
     4261 ctgtgcagga gtcgggacag cagctggtct tctggtctgg tcttgttcct agacctgggc
     4321 aggtctgagt tccaggtcta ccacatttag acctggctga ggtccagaat catcccttag
     4381 ccaggtttcc ctgctatacc ctaccctgaa gtactaacaa caggcaggac caagtcctac
     4441 gcttatggtt cttagtctcc agagcccatc gtcctaagaa accactacaa agaccctgcc
     4501 ctgtgatact taggtagaca gtaccttaga tggtctgcag actgccaggc catccccacc
     4561 tctgtggaac agggaagtgt cagaggctgc tggcatgagc aagagccctc cagagccaag
     4621 acctaagcac tcatgagctc agggagcgac tgtgggcgta gttaccaaga atccaaccgc
     4681 gagctagtaa gacaacaggg tgctgaaagt ggtggtctct gacgacttcc gggtgccagg
     4741 aatggagcag ggtccccctt gtcctcatcc ctaggcctat ggaccccagc acccgaatag
     4801 ctcttactct tgtccttctg tttctatctt gtgtccggag tgtgtctata tcttccagac
     4861 ctcattgtgc catgttgcta atcagtgttt tgtggtttgt tttgttggtt tgggttttgt
     4921 tgttgttgtt gttttgtttc tgtttttgta ctgagatgta tctgagcact ttagaaaagc
     4981 tgacttttaa gttcccactc tgtgaagaga acattccagt acctaacaag agctgggtgg
     5041 gctcaccacc agacaccatg actttttgga tttagaagtt caaatggttt ccacttggcc
     5101 ctgggaagga ttcagtgtat cccccaccag gtggccaggt ggttctcagc tgtgtactgt
     5161 aaacagtagg acagtgtcat cagttacctg tcaccagcag ccatgggtcc cttcctggca
     5221 gatctcattt gtgaagatgg tgagccagca gcattcaatc tcccttgtca atcgtgtcca
     5281 tgatcttcgc ctacccctga ttattttcac agcgatagca gagcatcctg gcaacagggt
     5341 attctggaac cacgctagaa cttgtgacca gattctagca ataaaattat ccagagca
//
