LOCUS       NM_001081116           10250 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Rho guanine nucleotide exchange factor 17 (Arhgef17),
            mRNA.
ACCESSION   NM_001081116 XM_133692
VERSION     NM_001081116.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10250)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 10250)
  AUTHORS   Garcia-Jimenez,I., Cervantes-Villagrana,R.D., Del-Rio-Robles,J.E.,
            Castillo-Kauil,A., Beltran-Navarro,Y.M., Garcia-Roman,J.,
            Reyes-Cruz,G. and Vazquez-Prado,J.
  TITLE     Gbetagamma mediates activation of Rho guanine nucleotide exchange
            factor ARHGEF17 that promotes metastatic lung cancer progression
  JOURNAL   J Biol Chem 298 (1), 101440 (2022)
   PUBMED   34808208
  REMARK    GeneRIF: Gbetagamma mediates activation of Rho guanine nucleotide
            exchange factor ARHGEF17 that promotes metastatic lung cancer
            progression.
REFERENCE   3  (bases 1 to 10250)
  AUTHORS   Lin,C., Yao,E., Zhang,K., Jiang,X., Croll,S., Thompson-Peer,K. and
            Chuang,P.T.
  TITLE     YAP is essential for mechanical force production and epithelial
            cell proliferation during lung branching morphogenesis
  JOURNAL   Elife 6, e21130 (2017)
   PUBMED   28323616
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 10250)
  AUTHORS   Isokane,M., Walter,T., Mahen,R., Nijmeijer,B., Heriche,J.K.,
            Miura,K., Maffini,S., Ivanov,M.P., Kitajima,T.S., Peters,J.M. and
            Ellenberg,J.
  TITLE     ARHGEF17 is an essential spindle assembly checkpoint factor that
            targets Mps1 to kinetochores
  JOURNAL   J Cell Biol 212 (6), 647-659 (2016)
   PUBMED   26953350
REFERENCE   5  (bases 1 to 10250)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   6  (bases 1 to 10250)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC116586.6 and
            AC150744.2.
            
            On Feb 6, 2007 this sequence version replaced XM_133692.9.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3593              AC116586.6         39885-43477
            3594-3671           AC150744.2         176766-176843       c
            3672-3854           AC150744.2         172022-172204       c
            3855-3971           AC150744.2         170113-170229       c
            3972-4064           AC150744.2         169815-169907       c
            4065-4241           AC150744.2         169461-169637       c
            4242-4292           AC150744.2         169118-169168       c
            4293-4402           AC150744.2         168755-168864       c
            4403-4488           AC150744.2         168565-168650       c
            4489-4607           AC150744.2         168038-168156       c
            4608-4821           AC150744.2         167524-167737       c
            4822-4895           AC150744.2         166946-167019       c
            4896-5095           AC150744.2         166278-166477       c
            5096-5400           AC150744.2         165797-166101       c
            5401-5650           AC150744.2         165150-165399       c
            5651-5737           AC150744.2         164839-164925       c
            5738-5805           AC150744.2         164441-164508       c
            5806-5954           AC150744.2         164053-164201       c
            5955-6129           AC150744.2         163111-163285       c
            6130-6399           AC150744.2         162758-163027       c
            6400-10250          AC150744.2         156091-159941       c
FEATURES             Location/Qualifiers
     source          1..10250
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.45 cM"
     gene            1..10250
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /note="Rho guanine nucleotide exchange factor 17"
                     /db_xref="GeneID:207212"
                     /db_xref="MGI:MGI:2673002"
     exon            1..3593
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     CDS             423..6596
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /note="Rho guanine nucleotide exchange factor (GEF) 17"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 17"
                     /protein_id="NP_001074585.1"
                     /db_xref="CCDS:CCDS40040.1"
                     /db_xref="GeneID:207212"
                     /db_xref="MGI:MGI:2673002"
                     /translation="MADGSPRPPLYRSVSFKLLERWSGGPGPREEDADTPGLRRRASC
                     RPAAAVPGQPSRRVSKLASGPPAAPAQPRPLRSLSPSVRQLSRRFDAAGLDDDSTGTR
                     DGGCSSGTTEEAAEGSERGAWPSVTEMRKLFGGPSSRRPSMDSEALGSTSPDRVSWEP
                     PTRDPRQPPTPPPRTCFPLAGLRSARPLSGPGIEGRRRRQHQQQERAQRPADGLHSWH
                     SFSQPQAGARASSSSSIASSYPVSRSRAASSSEEEEEGPQSQLGPQSPAYLGGHSSGS
                     DEDPNGEDGRRWRGRGLRPGRSQLVHGCSQDSDELNPGGLGSAGGVGSPEPPTSPRTS
                     MDEWGTGTQPCLPGPQESLRPMSDTGGAPFRVAKVSFPAYLASPAGSRGSSRYSSTET
                     LKDDDLWSSRSSVGWGVYRSPSFGTGDGLLLRPQTRSRSKGPVGTARPLRDGGLDLDK
                     NRQRKSLSNPDIASETLTLLSFLRSDLSELRVRKPSGGPGNRPLDGRDSPSAGSPMEQ
                     SESTLSQSPTSPTTRPTLKDLTATLRRAKSFSCSEKPMARRLLRTSALKPSSSELLLA
                     GSGAEEDPLPLVVQDQYVQEARQVFEKIQRMGAQQDDGNDVCPTSPDWAGDMTQGHRS
                     QEELSGPESNLTDEGIGADPEPLGAAFCSLDPAGVWRPLSSTSAQTNHHLGAGTEDSL
                     GGRALVSPETPPTPGALRRRRKVPPSGPNGTELSNGEASEAYRSLSDPIPQRHRAATS
                     EEPSGFSVDSNLLGSLNSKTGLPVTPAMDEGLTSGHSDWSVVSEENKDYQEVIQSIVQ
                     GPGALGRMGEDRIAGKTPKKKSLSDPSRRGELTGPGFEGPGGEPIREVEPMLPPSSSE
                     PILAEQWTEPEDPAPARGRAQSERSLPAPPASSTAHHDFHLDPKLTSVLSPRLTRRGS
                     KKRPARSSHQELRREEGNQDQTGSLTQTRSSSKHVRHASVPATFTPIVVPEPAMSVGP
                     PVAAPEPVGFPVRGHPALQAPSLEDVTKRYMLTLHSGDVPAPGPVDLPCLPPSAPPST
                     ETKPSGAARATPDEPAPASKCCSKPQVDMRKHVTMTLLDTEQSYVESLRTLMQGYMQP
                     LKQPENSLLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCVQTWHAQQKVGALLVQSFS
                     KDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIKPVQ
                     RIPRYELLVKDLLKHTPEDHPDHPLLLDAQRNIKQVAERINKGVRSAEEAERHARVLQ
                     EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSL
                     RRSSMSLYTAASVIDTASKYKMLWKLPLEDTDIIKGASQATNRETIQKAISRLDEDLA
                     TLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCCSLAFPPTKLELCATRP
                     EGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSC
                     AAPTFSSCPEPAPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGL
                     QPRCPREQPEPLRNPPETTLESTGPELDVEATAEEEAATTLAEPGPQPCLHISISGSG
                     LEMEPGPAKGDPQPELVPFDSDSDDESSPSPSGTLQSQASQSTISSSFGNEETPSSKE
                     ATAETTSSEEEQEPGFLSLSGSFGPGGPCGTSPMDGRALRRSSRGSFTRGSLEDLLSV
                     DPEAYQSSVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNKVFVSLAN
                     GELVVYQREAGRFWDPQNFKSMTLGSQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQ
                     LEHTFYVGQDSSRSVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRM
                     LAGSDAIIRQHKAACLRITALLVCAELLWVGTSAGVVLTIPTSPSTVSCPRAPLSPAG
                     LCQGHTGHVRFLAAVQLPEGFNLLCSTPPPPPDTGPEKLPSLDHRDSPRRRGPTSARP
                     KMLVISGGDGSEDFRLSSGGGGSSETVGRDDSTNHLLLWRV"
     exon            3594..3671
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            3672..3854
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            3855..3971
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            3972..4064
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            4065..4241
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            4242..4292
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            4293..4402
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            4403..4488
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            4489..4607
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            4608..4821
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            4822..4895
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            4896..5095
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            5096..5400
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            5401..5650
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            5651..5737
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            5738..5805
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            5806..5954
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            5955..6129
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            6130..6399
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     exon            6400..10250
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7846..7851
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /note="hexamer: AATAAA"
     polyA_site      7864
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /note="major polyA site"
     regulatory      10220..10225
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
                     /note="hexamer: AATAAA"
     polyA_site      10244
                     /gene="Arhgef17"
                     /gene_synonym="8030463K16; mKIAA0337"
ORIGIN      
        1 agagagctag ctgcttagag ggagggaaag ggagctggag cgggagctcg aggggaggca
       61 ggcgggccgc cgggcttggc aggcggactt tgagtgcagg aaccgagcct taggcccctc
      121 accggcagga ccgcgatgtc cctggcctct cccgcagagg ctaaggctgg gcctggggtc
      181 gccgcagggg cgagaggggc cgcccaggat ggaactcctg ccttttgtag ccgcggaaac
      241 ttgatcttcg actgataaac ctctgctcac gtctccgcac cctcctccac agccgccgca
      301 cgctgcgggt gcaggaccca ggctctcgga ccgtggccac tgcgcgccct cggagtggga
      361 gtgcaggggg ggttggccgc ggcgtcccga ggccagcccc cccggagtga ctagcaccaa
      421 ccatggcgga cgggtcacct cgacccccac tttatcgcag cgtctcgttt aaactgctgg
      481 agcgctggag cggcggaccg gggccgaggg aggaggacgc ggacacccct gggttgcggc
      541 gccgagcttc gtgccggcca gccgcggcag tcccgggcca gccctcccgg cgcgtgtcca
      601 agctggcgtc ggggcccccg gccgcccccg cgcagccgcg cccgctccgc agcctctcgc
      661 catcggtgcg ccagctctcc cggcgcttcg acgcggcggg tctggacgac gactccactg
      721 gtacccggga cgggggctgc tcctccggca ccacagaaga agctgcggaa ggctctgaac
      781 gtggggcctg gcccagcgtc acagagatgc gcaaactctt cggcggtccg agctccagac
      841 gacccagtat ggactctgag gccctggggt cgaccagccc cgacagagtt tcgtgggagc
      901 ccccaactcg cgatccccgg caacctccga cgccacctcc tcgaacgtgc tttcctctgg
      961 ctggcctgcg ttctgcgcgg ccgctgtccg ggcccgggat cgaggggagg cgacgtcggc
     1021 agcaccagca acaggagcgg gcgcagcgtc cggcggatgg tttacattct tggcatagct
     1081 tctcccaacc gcaggccggg gcccgggcct cctcctcctc ctccattgcc tcctcctatc
     1141 ctgtcagccg cagccgggct gctagttcca gcgaggagga agaggaggga ccgcagtcgc
     1201 agcttgggcc tcagagtccg gcctacctcg gcggccactc ttcgggcagt gacgaggacc
     1261 caaatggtga ggatggccgt cgctggagag ggagaggtct ccggcctgga cgctctcagt
     1321 tggttcacgg ctgcagccag gacagtgacg agctaaatcc gggaggcttg ggatcagcgg
     1381 ggggtgtcgg gagccccgaa cctccgacgt ctccaagaac ctcaatggat gagtggggta
     1441 ctggtacaca gccatgcctc ccaggtcccc aagagagctt aaggcctatg tccgacactg
     1501 ggggtgcacc tttccgtgtg gctaaggtga gctttcctgc gtacctggcc agcccagctg
     1561 gctcccgagg aagtagtcgc tattccagca cagagaccct caaagatgac gacctatggt
     1621 caagccgtag ttctgtgggc tggggtgtat atcgatcccc aagttttgga actggagatg
     1681 ggcttcttct gcggccccag acgaggtccc gcagtaaggg acctgtaggc actgccaggc
     1741 cgctgaggga tggaggactg gacctagata agaaccgaca acgaaagtcc ctatcgaatc
     1801 cagatatcgc ctctgaaacc ctgacgctgc tcagtttcct tcgttcagac ctttcagaac
     1861 tgagggtccg aaagcccagt gggggccctg ggaacaggcc cctagatggc agagactcac
     1921 catcagcagg tagcccaatg gaacaatcgg agtccacact gtctcaaagt ccaacgtcac
     1981 ccaccacccg gcccaccctc aaggacctga cagctaccct acgcagagca aagtcattca
     2041 gctgttcgga aaagcccatg gcccggcgcc tgctccgcac cagtgccttg aagcctagct
     2101 cctcagagct cctactggca ggttctgggg cagaggaaga cccattgcca ctcgtggtcc
     2161 aggatcagta tgtacaggaa gcccgtcagg tttttgagaa gatacagcga atgggtgcac
     2221 agcaggacga tggaaatgat gtctgcccta caagtcctga ctgggcaggg gatatgaccc
     2281 aagggcatcg gtctcaggag gagctctctg gccctgagtc caacctgacg gatgagggca
     2341 ttggagcaga ccctgaacct cttggtgctg ccttttgcag cttagatcct gcaggagtgt
     2401 ggcgacccct ttcctctact tcagcgcaga caaaccacca ccttggggcc gggacagaag
     2461 acagcctggg tgggagggcc cttgtgtctc ctgagacccc tccaactcca ggtgccctcc
     2521 gcaggagacg aaaagtgcca ccttcaggcc ctaatggaac tgaactaagt aatggggagg
     2581 ctagtgaggc ctacaggtcc ctgagtgacc ctattccaca gcgtcatcgg gctgccacct
     2641 ctgaggagcc ctcagggttc tctgtggaca gcaatcttct gggctcgctg aactctaaga
     2701 cagggcttcc agtgacccca gctatggatg agggcctgac cagcggccac agtgactggt
     2761 ctgtggttag cgaagagaac aaggactatc aggaagtcat tcagagtatc gttcaggggc
     2821 ctggtgcctt ggggcgtatg ggagaagaca ggattgctgg caagaccccc aagaagaaat
     2881 ctctgagtga ccctagtcgc cgtggggagt tgactgggcc tggatttgag ggcccaggag
     2941 gggagcccat tcgagaagtg gagcccatgc tgcctccgtc cagcagtgaa cctatccttg
     3001 cagagcagtg gacagagccg gaagaccctg ctcctgccag gggcagggca cagtcagaga
     3061 ggtccctacc tgccccacct gcctcctcca ctgcccacca tgacttccat cttgacccca
     3121 agctgaccag tgttctctcc cctcggctca cccgtcgagg ctccaagaag cgcccagccc
     3181 ggagcagtca ccaggagctt cggagagagg agggcaacca ggaccagact ggtagcttga
     3241 cacaaactcg gtcttcctcc aaacatgttc gccacgccag tgtgcctgcc acctttacac
     3301 ctattgtggt acccgagcct gcgatgtctg tgggaccccc cgtggctgcg ccagagcctg
     3361 tgggctttcc tgttagaggc catcccgcct tgcaggcacc atcacttgag gatgtgacta
     3421 aacggtacat gctgaccctt cactctggtg acgttcctgc cccaggtcct gtggacctac
     3481 cctgcttgcc tccttctgca ccgccctcca ctgagaccaa gccctctggg gctgccaggg
     3541 caactccaga tgagccagcc ccagcgagca agtgctgtag caagccacaa gtggacatga
     3601 ggaagcacgt gaccatgacc ctgctggaca cagagcagtc gtatgtggag tcactgcgca
     3661 ccctgatgca gggctacatg cagccactga agcagccgga gaactccttg ctgtgcgacc
     3721 cgtctctggt ggacgagatc ttcgaccaga tccccgagct cctggagcac catgagcagt
     3781 tcctggagca ggtgcggcac tgcgtgcaaa cgtggcacgc ccagcagaag gtgggagccc
     3841 tgctcgtcca gtcgttttcc aaagacgtct tggtgaacat ctattcggcc tatattgata
     3901 acttcctcaa tgcaaaggat gctgtgcgtg tagctaagga ggccaggcca gcctttctca
     3961 agttcttgga gcaaagcatg cgtgagaaca aggaaaagca ggcgctgtcc gacctcatga
     4021 tcaagcctgt gcagagaatc ccacgctatg agcttctggt gaaggacctt ctgaagcaca
     4081 caccggaaga ccatccagac cacccactgc tgctcgatgc tcagcgcaac atcaagcagg
     4141 tggctgagcg catcaacaag ggtgtgcgga gcgctgagga ggccgagcgg catgcccgcg
     4201 tgcttcagga gatcgaagcc cacatcgagg gcatggagga tctccaggcc cccctgcggc
     4261 ggttcctgag gcaggagatg gttattgaag tgaaggcaat tggaggcaag aaggaccgat
     4321 ccctcttcct gttcacagac ctcattgtct gtaccaccct gaaacgaaag tcgggctcgc
     4381 tgaggcgcag ctccatgagc ctgtacacag cagccagcgt cattgataca gccagcaaat
     4441 acaagatgct gtggaagctg ccactggaag acacagacat catcaagggg gcgtctcaag
     4501 ccaccaatcg ggagaccatc caaaaagcca tcagccgcct ggatgaggac ctggccaccc
     4561 tgggccaaat gagcaagctc tccgagagcc tcggcttccc ccaccagagt ctagacgatg
     4621 cactgaggga tctctcggcc gccatgcacc gggacctgtc agaaaagcag gcgctatgct
     4681 gctccctggc cttcccgccc accaagctgg agctgtgcgc cacccggccc gagggcaccg
     4741 actcctacat ctttgagttt ccccacccgg atgcccgcct gggctttgag caggcctttg
     4801 atgaggccaa gaggaagctg gcatccagta aaagctgtct agaccctgag ttcctgaagg
     4861 ccatccctat catgaagact cgcagtggca tgcagttttc gtgtgctgcc cccaccttca
     4921 gcagctgccc agagccggcg ccagaggtct gggtgtgcaa cagtgatggc tacgtaggtc
     4981 aggtgtgcct gctaagcttg agggcggaac cagatgtgga ggcctgcatc gctgtttgtt
     5041 ctgcccgcat tctctgtatc ggagcggtgc caggcctgca accacgctgc ccgcgagagc
     5101 agccagagcc cttgagaaac cccccagaga ccacactgga atccactggg ccagagctag
     5161 atgttgaggc cacagctgag gaggaggcag cgacgacgct ggctgagcca gggcctcagc
     5221 cttgcctgca catttccatc tcaggatcgg gcctggagat ggagccaggc cctgctaagg
     5281 gtgaccccca gcccgagttg gtgccctttg acagcgactc tgacgacgaa tcttcaccca
     5341 gcccctccgg gactctacag agccaagcca gccaatctac catttcctcc agctttggaa
     5401 atgaagagac cccaagctcc aaggaagcca ctgcagagac gaccagctct gaggaagagc
     5461 aagagcctgg cttcctgtca ctctctggct cctttgggcc aggtggtccc tgtggcacca
     5521 gcccgatgga tggaagagcc cttcgccgct ccagccgtgg ctctttcaca aggggcagcc
     5581 ttgaggacct gttgagtgtg gaccctgagg cctaccagag ttccgtgtgg ctgggcaccg
     5641 aggatggctg tgtccacgtc taccagtcct ctgatagcat ccgtgatcgc aggaacagca
     5701 tgaagctcca gcacgctgcc tccgtgacct gcatcctgta tctgaataac aaggtgttcg
     5761 tgtctttggc caatggagaa cttgtagtct accaaaggga agcagggcgt ttctgggatc
     5821 cccagaactt caaatcgatg accctgggtt ctcaggggag ccccattacc aagatggtgt
     5881 ctgtgggtgg acgactgtgg tgtggctgcc agaaccgggt ccttgtcctg agccctgaca
     5941 cattgcagct ggagcacaca ttctacgtgg ggcaggattc cagccgaagt gtggcttgca
     6001 tggtggactc cagcctgggt gtgtgggtga ccttgaaagg tagtgcccat gtatgtctct
     6061 atcatccgga cacctttgag caactggcgg aggtagatgt cacccctcct gtgcacagga
     6121 tgctggcagg ctcagacgcc atcatccggc agcacaaggc agcctgcctg aggatcacgg
     6181 cgctgctggt gtgtgcggag ctgctgtggg tgggcactag tgccggggtc gtgctgacta
     6241 tacccacctc tccaagcacc gtcagctgcc cgcgagcacc tctcagccca gctggcctgt
     6301 gccagggcca cactggccat gtccgcttcc tggctgcagt ccagctgcct gaaggcttca
     6361 accttctatg ttcaacccca ccgcctcccc cagacacagg ccctgagaag ctgccttccc
     6421 tggatcaccg ggactcccct cggcgccgag gccccacctc agccaggcct aaaatgctgg
     6481 tcatcagtgg tggtgatggc tctgaggact tccgactcag cagcgggggt ggcggcagca
     6541 gcgagaccgt gggccgagat gacagcacaa accacctact cctgtggagg gtgtgagcct
     6601 gccctctgtg gcccaggact cacctgtcca cctgccctca gcctgcctgt ctcctcccag
     6661 gccacatgca gaccttgagc agagtgtcca agcaggggca taccattcgg actctgtctc
     6721 atccttgtgg aagcatccct ggtagaaggc caccagcgag gccgagcaag gcctctggta
     6781 cccactgact accctagagc tcccctttgg gagcagggtg gagatgtggg ggctgcccag
     6841 gaactgtccc tgaagcttct accaaagaca cagccaggcc tggaccccac agggctgggg
     6901 aggccgtgtg caatatgtgg agagctctct ggggcagtgc gaaggctaag gggcggcaac
     6961 ccttttctat gtacagtatt tatgttactt tctagatgaa tactttccaa agcacttatt
     7021 tatgcagtga cctggggcag gacgtgatgt gaggaaaaga caggaggaaa aaagcctgtt
     7081 cctgcctgag aggccaccct ggagccctaa ccaagttgtc ctggaaggac caatgcccat
     7141 gtgttacaca cacgcacgca cacatacaca cacaccacac tcacactcac tctgcatgtt
     7201 cagggcacta agacactgtc ccttaaccaa gctccagccc tccctgatgg cgctgccatc
     7261 ccaattctga agcaaagcct gctcgatccg ctcactgggg agcttccagg ggttagcatt
     7321 tccaaggtga cgcctgaggt tccccagtgt gggaacagtg gtaggtctgg gaccgggctt
     7381 tctcaggtaa gagaaaaggg ccttcagtcc tcacagctgg ctcaagcccc agcctctgcc
     7441 tccccatgtc tcatgcactg gcacaatggt caccttgtgg ggacctatga gtcccctttc
     7501 tctgaccact gaatcgagtc cctctctgta aacacccacg ctgccaaggg cagccccttc
     7561 aggaaggaca ccccaccccc accccccaga gttgaggggc tagacataac ctttttaact
     7621 gagaaggccg tcgtccctca ccgccaggct gcagggagcc accccgaccc tcagcccctt
     7681 gcttcagcta caactccaaa ggtctggttt cagatagggt ttgtttgttc tgtttgattt
     7741 tgtttttctt tggggtgggt gggtcattgt ggtcttagat gatgtttctc ttgctaccaa
     7801 acagccttgt gttaactctc ctcagatgat gaaatttaaa gagtcaataa atagaaacac
     7861 taaatgatgg ctcccccggg ccttgggcca tcatggcctc ctgccagctg tctccctaag
     7921 gacgagggct ccctgactct gcctcaattg ggtcaaaggg aggagataag gaagtcctgg
     7981 gtgatggggt tgacactgaa cctgtgttgt cacgggcaga ctgcggctgt ctgggcttca
     8041 gtctccttag aagaacccag gagttctgaa tgttagaatt ccttacagct catatgcgta
     8101 tcaatggtgt gtcagtctag ccctcccgag tccagctagg tttgggtttg ggtgtctgac
     8161 ccagggctag agttcctgtc taaggcgcct gtggagcaga actaccacac aagtcgggct
     8221 gattctggtc caaagagatg tgtcattaca caagactgca aaggatttaa gtgcccagca
     8281 acatggggct gctctctagg ggccaagagc cccccacaca cacaccatgg tgtcttcccc
     8341 atgggactaa gtggccctca cagcagaggt caggttatgc cgaatctctg cttaggtcag
     8401 cccaaatgac tcacttcaaa attcactttc ctggactggg gcaataatag tttagtggtt
     8461 aagagcacgg actgctcttc gagaggaccc aggttcagtc cccagcagct cacagccatc
     8521 tataactcca atcccaaggg aatcaaatgc ccttgtctgg cctccaggga tacggcatgc
     8581 atgtggccac aaacctccat gcaggcaaaa gacccatact cacaaaataa tatattttca
     8641 ataaaagaaa gtctgttttt gcactgaaca gatagttcag ttgacagact gtatgcttgg
     8701 catgtgggaa aactgaagca gggtattctt gagttcaaaa ccagcttaga gaagttatga
     8761 tgatatgtgc ctataatctt agcgcttgag tcactggcca gtgggtctct gtgaattcac
     8821 acccagcctg gtctaccaag catgttctag gtcagccagt gctgcatggt gagacccctt
     8881 ccccatttca aaacaaaatg gttctacatg gcaagacaca cacacaaagg gagaaagtgt
     8941 tggtgtgtgc ttttattaac tcgcgtgcat ccctcagggg tctgctgggt cttcaacacc
     9001 acaggacgtg tacaggacat cttgctagca gcattttcgt gaggagacgg ttgtgcctgt
     9061 gtggaattca ggatgaaatg gaaggaacac aggctttgca tggaacggct tctctttgga
     9121 atcttgtctg atagcagcca tgtgaccagg ccaagttatt tccttctcag taatggggtc
     9181 tgataacctc ttttccccta caggatggtt ggctagtgca tgtagttctt gaaatgcaaa
     9241 gaggtccatt tctggccctt aaatctaaag ggtgcctgcg tctggagacc tgagctggcg
     9301 gtcagagccc agtgatctac atgttgaagg cccacctcag gctcctcccc gctgccacta
     9361 gtccagttat ttgcatttct gacagtggct gccaccttta gtgcttcagt catttctgct
     9421 actccaggat ttctgcctca acagaggccc aaagcagact tcactttcag gactagatac
     9481 atagggctgg gtctgcgcca tcctcaccgg gaatatggct ggcacatagc acaaccactt
     9541 agaagacagc ctgccagggc atgggctggc ctgaggacag gtgtccatct ggatcaggca
     9601 ctcagcatga gtagggcggt cctgaaggaa caggcctcag gctcatcccc aagggagtct
     9661 cctggaaaaa ttacaacctg ggctgttcat tattagttct ccaggggcac aggcccaccg
     9721 aaggccaatt aaattaaaac cttagctagg acccaggtac cagtatgttt attgggagcc
     9781 actgatacat agcacttata tgaggaagta cacagtgtac agctcagtat agaacggcca
     9841 agaggcatcc atcaccccaa cagctctcct tatactcgtg gccacccagg cttgagacac
     9901 tggggtgtgg tcttcccaga cagcatagag aactgcctta aagggcatga ttgtgggtga
     9961 gaggaagcag gaccaaggtt tggtgtgaag caggattatg caaggagggg tgtaacatgc
    10021 aggggacggg atataagatg caaggagggc cataagagcc tgatgtgaac ggtctgttgt
    10081 acagacagaa tgagagaagg ctgaaggagc ttggatggat gctctgaggg cagggtgtgt
    10141 tctcagcttc atccctaagc ctacttgctg tagcaagcat caataagtgc tcaataaatg
    10201 ttgaattcat gtttaatgaa ataaacattg gagaatccag gtgagacaca
//
