LOCUS       XM_006501269            6837 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus Rho guanine nucleotide exchange factor 11
            (Arhgef11), transcript variant X7, mRNA.
ACCESSION   XM_006501269
VERSION     XM_006501269.2
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000069.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Feb 9, 2015 this sequence version replaced XM_006501269.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6837
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="3"
     gene            1..6837
                     /gene="Arhgef11"
                     /gene_synonym="mKIAA0380; PDZ-RhoGEF; Prg; RhoGEF"
                     /note="Rho guanine nucleotide exchange factor 11; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 mRNAs, 96 ESTs, 437 long SRA reads, 2 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 46 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:213498"
                     /db_xref="MGI:MGI:2441869"
     CDS             1214..5905
                     /gene="Arhgef11"
                     /gene_synonym="mKIAA0380; PDZ-RhoGEF; Prg; RhoGEF"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 11
                     isoform X7"
                     /protein_id="XP_006501332.1"
                     /db_xref="GeneID:213498"
                     /db_xref="MGI:MGI:2441869"
                     /translation="MSIRLPHSIDRLSSLSSLGDSTPERTSPSHHRQPSDTSETTGLV
                     QRCVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMRAGVKEGDRIIKVNGTMVTNSSH
                     LEVVKLIKSGAYVALTLLGSSPSSIGVSGLQQNPSLSGGPRVNPMIPPPPPPPPLPPP
                     QHITGPKPLQDPEVQKHATQILRNMLRQEEKELQRICEVYSRNPASLLEEQIEGARRR
                     VTQLQLKIQQETGGLVDVLPLCGETSQRTCEGRLSVDSQEADSGLDSGTERFPSISES
                     LVNRNSVLSDPGLDSPQTSPVILARVGQHHRRQGSDAAVHPLNHQGIDQSPKPLIIGP
                     EEDYDPGYFNNESDIIFQDLEKLKSHPAYLVVFLRYIFSQADPGPLLFYLCSEVYQQT
                     NPKDSRNLGKDIWNIFLEKNAPLRVKIPEMLQAEIDLRLRNSEDPRSALYEAQEAVMP
                     EIQEQINDYRSKRTLGLGSLYGENDLLDLDGDPLRERQMAEKQLAALGDILSKYEEDR
                     SAPMDFAVNTYMSHTGIRLRESRPSSTAEKTQSAPDKDKWLPFFPKTKKQSSNSKKEK
                     DALEDKKRNPILRYIGKPKSSSQSTFHIPLSPVEVKPGNVRNIIQHFENSHQYDVPEP
                     GTQRLSTGSFPEDLLESDSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDA
                     AAEATRLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPNLGFCTDVILPHLLED
                     DLGQLSDLEPEPEVQNWQHTVGKDVVANLTQREIDRQEVINELFVTEASHLRTLRVLD
                     LIFYQRMKKENLMPREELSRLFPNLPELIEIHNSWCEAMKKLREEGPIIRDISDLMLA
                     RFDGPAREELQQVAAQFCSYQSVALELIRTKQRKESRFQLFMQEAESHPQCRRLQLRD
                     LIISEMQRLTKYPLLLENIIKHTAGGTSEYEKLCRARDQCREILKFVNEAVKQTENRH
                     RLEGYQKRLDATALERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLQVLLL
                     EDLVVLLQRQEEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLIRSVATDKRAFFIIC
                     TSELGPPQIYELVALTSSDKNIWMELLEEAVQNATKHPGDAPVLNHPSPPGSQEPAYQ
                     GSTSSRVEVNDSEVYPTEREPKKPSEGPGPEQRGQDKQLLAQEGPEQEEDAEELRALP
                     CPPPSLDGENRGIRTRDPVLLALTGPLLMEGLADAALEDVENLRHLILWSLLPGHTVK
                     TQAAGEPEDDLTPTPSVVSITSHPWDPGSPGQAPAISDNTQFPRPEGSQPEGEDVALC
                     SLAHLPPRTRNSGIWDSPELDRNPAEEASSSEPAGSYKVVRKVSLLPGGGVGAAKVAG
                     SNVTPALPESGQSESELSEVEGGAQATGNCFYVSMPAEPLDSSTEPPGTPPSLSQCHS
                     LPAWPTEPPQHRGVTGGQRSSLVLRDMGVIFHTIEQLTVKLHRLKDMELAHRELLNSL
                     GGESSGGTTPVGSFHTEAARWTDYSLSPPAKEALTSDPQNNQEQGSYPEEGSDTPLED
                     SATDTASSPGP"
ORIGIN      
        1 gggccggaag cgcagcggcc gcgacgcgga cgccgggagc ggccgagcgg ggaggctgtg
       61 gctggcgggc gggtgggcac ggaggccgag gccgcggccc gggctctccg cgccgctgtg
      121 gagggcgccc tggccctaac cgagccgcaa caatactagg agcgggtcgc cggacacgat
      181 cggcgggcga gggggaagcg ggactaccgc tccagagcgc tgcggcgaga gagactttcg
      241 gagcctggac gtgctggagc acacagagct gactgaggaa attgtctgag aaaaaggccg
      301 atctgaggct gggttaggtg gaggaacctg caagtcgaaa gggaaaagaa ggtttaagat
      361 ttcctggggg tttggccaat gctaccgttt tgaaggtaga aagcattgcg cttcaggtgt
      421 tttgtgattg ttgtgtgtgt gtctgcacaa ttggttcatt tcagaattca aaaaccttta
      481 ctgtagaaga agatggttgt tttgttttga tttttaaaag aaatccgcaa attttgcttc
      541 ccagggctgc actggaccgt gttgtgtaca tactgctgtg tggttttatt tattttaact
      601 gtgcaaatcg tctggaagat ttttctccca agtgccattt cggatttgtt cagccttttt
      661 gttttgtttt gttttgtttt tgtttttcct tccctggaat aattctgctg ttggcatttt
      721 aagcatttgg aaaccagaga tttttttttt caacctttgg agcttaaggc ttccctgtca
      781 acagaaggac agctggggaa actggattga aaggatggct tttatctgtc tgcaactaag
      841 actgatattt tgaagtcaga ttctttctgt ggttcagttt ttagcccgta gggctaacct
      901 tgaagagatt tgtggttaac agtttggttt ctaagaaggt catagttttt cctctctttt
      961 tttcttttca ttttcttttt taagacgagg gaggggaagg ttaagggtga aggaaggagg
     1021 agaccatgtt aaccgataga agcagaatag cactgcagtt accagggtcc tgacagctgg
     1081 aagaaacaag gattcagtct tcaacttggg aggccttcct ctcaccttcc ttcaaaattg
     1141 caagggactc aggcctgatc aagacgccca aagaaactac aggattccag aactgtggag
     1201 acacggagaa accatgagca tacggttgcc ccatagtata gacaggttaa gtagcctgtc
     1261 ttctctggga gattctacac ctgaacgcac atccccttct caccaccgcc agccctctga
     1321 cacctctgag acaacaggtc ttgttcagcg ctgtgtcatc atccaaaagg accagcatgg
     1381 ctttggcttc acagttagtg gagatcgcat tgtgctggtg cagtctgtgc gccctggagg
     1441 cgcagccatg agagctggtg tgaaagaggg tgaccggatc atcaaagtaa acggcaccat
     1501 ggtgaccaat agctcacacc tggaggtagt gaagcttatc aaatctggcg cctatgttgc
     1561 gcttaccctc ctgggctctt ctccttcctc catcggtgtc tctgggctcc agcagaaccc
     1621 ttctctgtca ggagggccca gagttaaccc catgattcct ccaccacctc ctcctccacc
     1681 cttgccacct ccacaacaca ttactggacc taaacctcta caggatcctg aagtccaaaa
     1741 gcacgccact caaatcctca ggaatatgct aaggcaggag gagaaggagt tacagcgtat
     1801 ctgtgaggtg tatagtcgga accccgccag cctgctagaa gagcaaatcg aaggtgcccg
     1861 gcggcgagtc actcaattac agctgaagat ccagcaggag actggtggct tagtggatgt
     1921 acttccactc tgtggtgaga ccagccagag aacatgtgaa ggccgcctct ctgtggactc
     1981 ccaggaggca gacagtggct tggactcagg gacagaacgc tttccctcca tcagtgagtc
     2041 attggtgaat cggaactcag tattgtcaga tcctggacta gacagcccac aaacctcccc
     2101 tgtaatcctg gccagggtgg gccagcacca caggcgacag ggctcagatg cagcggtgca
     2161 ccccctcaac caccagggta tagatcaaag cccaaagcct ctgattattg gcccagagga
     2221 agattatgac ccaggctatt tcaacaatga gagtgacatc atctttcaag atcttgaaaa
     2281 actgaagtca catccagctt acttggtagt atttctacgt tacatcttct ctcaggcaga
     2341 ccccggcccc ctgctttttt atttgtgttc agaagtttat cagcagacaa atcccaaaga
     2401 ttcccgaaat ctggggaaag acatctggaa tattttccta gagaaaaatg cgcctctcag
     2461 agtgaagatc cctgagatgt tgcaggctga gatcgaccta cgcctgcgaa acagtgagga
     2521 ccctcgcagc gcgctttatg aagctcagga ggcagtcatg ccggagatcc aggagcagat
     2581 caatgactat agatcaaagc gcactctggg gctgggcagc ctctatggtg aaaatgacct
     2641 actagacctg gatggggacc ctcttcgaga gcgccaaatg gctgagaagc aactggctgc
     2701 ccttggagat atcttgtcca aatatgagga agatcggagt gctcccatgg acttcgctgt
     2761 taatacctac atgagccaca ctgggatccg tcttcgggag tctcgacctt ccagcacagc
     2821 agaaaagacc cagtctgccc ccgacaagga caagtggctg cccttcttcc ctaagaccaa
     2881 gaagcagagc agcaattcca agaaagaaaa ggacgccttg gaggacaaga agcgaaaccc
     2941 catcctcaga tacattggga agcccaagag ctcttctcag agcacatttc atattccctt
     3001 gtcccctgtg gaagttaagc caggcaatgt gaggaacatc attcagcact ttgagaacag
     3061 ccatcagtat gatgtcccag agccggggac acagcgactc tcaacaggaa gctttcctga
     3121 ggacctgctg gagagtgaca gttcacgctc agagattcgc cttggccgct ctgaaagcct
     3181 caagggccgg gaggagatga agcgatcccg gaaggcagag aatgtgcccc ggtctcgaag
     3241 tgatgttgac atggatgctg ctgctgaggc tactcgcctt catcagtcag cctcatcctc
     3301 tgcctccagc ctctccacca ggtctcttga gaacccaacc cctcccttca cccccaaaat
     3361 gggccgcagg agcattgagt cccccaatct ggggttctgt acagatgtca tccttcccca
     3421 cctccttgag gatgatctgg gccaactgtc tgacctggag ccagagccag aagtccaaaa
     3481 ctggcagcat acagtgggca aggatgtggt ggcaaacttg acacagaggg aaattgaccg
     3541 gcaagaggtc atcaatgagc tctttgtgac agaagcatcc cacctgcgca cgctacgagt
     3601 cctggacctc atcttctacc agcgcatgaa gaaggagaac ctaatgccac gggaagagct
     3661 gtcaaggctc ttccctaatc tgcctgaact catagagatc cacaattcct ggtgtgaagc
     3721 catgaagaag ctccgggagg agggccccat tatcagagac atcagtgacc tcatgctggc
     3781 tcggtttgat ggtcctgccc gagaagagct ccagcaagta gctgcacaat tctgttccta
     3841 tcagtcagta gccctggagc taatcaggac taaacaacgc aaggagagtc gattccagct
     3901 cttcatgcag gaagccgaga gccaccccca gtgtcggcgt ctgcagcttc gtgacctgat
     3961 catctctgag atgcagcggc tcactaagta cccactgctg ctagagaaca tcatcaagca
     4021 cacagcgggt ggcacatctg agtatgagaa gctctgccgt gcccgggacc agtgccgaga
     4081 gattctcaag tttgtgaatg aagcagtgaa gcagacagag aaccgtcacc gcttagaagg
     4141 gtaccagaaa cgcctggatg ccactgctct agagcgggcc agcaacccct tggcagcaga
     4201 gttcaagagc ctggatctta cgacaaggaa gatgatccac gaggggcctc tgacctggag
     4261 gatcagcaaa gataagaccc tggacctcca ggtgctgtta ctcgaggacc tggtagtgct
     4321 gctgcagaga caagaggaga agctgctgct caagtgccac agcaagacag ctgtgggctc
     4381 ctcagacagc aagcagacct tcagccctgt gctgaagctc aatgccgtgc tcatccgctc
     4441 tgtggccaca gataaacgag ccttcttcat catctgcacc tccgagctgg gccctcccca
     4501 gatctatgag ctggttgcat tgacatcatc agacaagaat atatggatgg agctcttaga
     4561 agaggctgtg cagaatgcca ccaagcaccc tggagatgcc ccagtactca accatccctc
     4621 accaccagga tcccaggagc cagcctacca gggctccacc tccagcaggg tagaggtgaa
     4681 tgactcggaa gtgtatccca ctgaaagaga acccaagaag ccatctgaag gccccgggcc
     4741 cgagcagaga ggtcaagaca agcagctgct agcacaagag gggcctgagc aggaggagga
     4801 tgcagaggag ctgagggccc tgccttgccc tcctccctcc ctggatggag aaaacagagg
     4861 catcaggaca agggaccctg tccttctggc cctcacaggc cctctgctca tggagggact
     4921 tgctgatgct gccctggaag atgtggagaa cttgcggcac cttatcctgt ggagcctgct
     4981 gcctggtcac actgtgaaga ctcaggctgc tggcgagcct gaagatgacc ttacacccac
     5041 cccttctgtc gtcagcatta cctctcaccc ctgggaccca ggatccccag ggcaagctcc
     5101 tgctataagt gacaacaccc aatttccaag gccagaggga agccagccag agggcgagga
     5161 tgttgctctc tgttctctgg cacacttgcc accaaggacc agaaattctg gcatctggga
     5221 ctctcctgag ctggatagga atccagctga agaggcttca agctcagaac cagcaggaag
     5281 ttacaaagtt gtaaggaaag tctctctact ccctggtggt ggtgtcggtg cagccaaggt
     5341 ggcgggcagc aatgttaccc ctgcactccc agagagtggc cagtcagaat ctgagctatc
     5401 tgaagtggaa ggcggagcac aggctacggg gaactgtttc tatgtcagca tgccagcaga
     5461 acctctggac tctagcactg agcctcctgg gacaccccca agtctctcgc agtgtcacag
     5521 cctccctgca tggccaacag agcctccgca acacagggga gtcactgggg gtcagcgttc
     5581 cagcctggtc ctcagggata tgggtgtgat cttccacacc atcgagcaac tgaccgtcaa
     5641 gcttcacaga ctcaaggaca tggagctggc ccacagagag ctgctcaact cccttggagg
     5701 agagtcgtct ggtggaacca ctcctgtggg aagttttcac acagaggcag ccagatggac
     5761 agactactcc ctctctcctc cagccaagga agccctgacc tctgaccccc aaaacaatca
     5821 ggagcagggg tcctaccctg aagaaggctc cgacaccccc ctggaagaca gtgccacaga
     5881 cacagcttcg tcaccaggac catagccatc cagacaacca gagtctggcc tgagccagag
     5941 cgccacatta ggagatccga gcctccccgt gaaagatact gtgaggcctg ggaatccctc
     6001 atgttgcctg gtctgttccc accagacagt ccagtttagt gtctcttcct cctgttagcc
     6061 caagtctccg tggctttcgt ctcctaagca tgctgaccac aatagaaagg cctccacccc
     6121 acatagccag tgtggggtgt gctatgtgca cagtgccctt gaggaggctt atgtataaat
     6181 gcactttctt cctcctcttc ttcctaggcc ccgagacagc tagatgcctg gctctcctct
     6241 ttgcccttta gtttcctata aatatgtcta ttgtatgtgt atctttgcca ttgtaaataa
     6301 cttagccttt tattctgtcc ctggcatgtt caaccagtca cagagagcca ggcagcagcc
     6361 ccgcacaggg ccatgattgt ttatgtccca ctggcaggga ggtctcccag attccagtgc
     6421 tgtcaagctc cagggcctgc ccacctctga agcctaggcc ttctcagtgt caggaaatgc
     6481 tcctgcaggg agtgtcttac ccagcccttc cccacttgcc ccatagaaac aatacaccag
     6541 gtacggatct caacacagac tctcaagaga gatgtggagt ggattgctgg agtccctgag
     6601 ttaagtcagg gcccttcctt ccccaggggc cacagcaccg ttggctcatc accctgtcct
     6661 cacgccactc cctacaatga acatacacac tgtgctaggt gtatatatac atatatataa
     6721 atatatataa tatataaaat atagatatgg aaatgactgt tttactgtta aaataatgta
     6781 tactcttatt ttcttccttt catggttaag atttttttaa agaaaagtta aatattc
//
