LOCUS       NM_001112723            4408 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Rho guanine nucleotide exchange factor 10-like
            (Arhgef10l), transcript variant 3, mRNA.
ACCESSION   NM_001112723
VERSION     NM_001112723.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4408)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4408)
  AUTHORS   Tang,J., Zhang,X., Chang,H. and Wang,D.
  TITLE     Investigating the effect of ARHGEF10L gene on tumor growth in
            gastric cancer in a nude mouse model using quantitative MRI
            parameters
  JOURNAL   J Cancer Res Ther 18 (7), 1926-1930 (2022)
   PUBMED   36647951
  REMARK    GeneRIF: Investigating the effect of ARHGEF10L gene on tumor growth
            in gastric cancer in a nude mouse model using quantitative MRI
            parameters.
REFERENCE   3  (bases 1 to 4408)
  AUTHORS   Lee,S., Sears,M.J., Zhang,Z., Li,H., Salhab,I., Krebs,P., Xing,Y.,
            Nah,H.D., Williams,T. and Carstens,R.P.
  TITLE     Cleft lip and cleft palate in Esrp1 knockout mice is associated
            with alterations in epithelial-mesenchymal crosstalk
  JOURNAL   Development 147 (21) (2020)
   PUBMED   32253237
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4408)
  AUTHORS   Bebee,T.W., Park,J.W., Sheridan,K.I., Warzecha,C.C., Cieply,B.W.,
            Rohacek,A.M., Xing,Y. and Carstens,R.P.
  TITLE     The splicing regulators Esrp1 and Esrp2 direct an epithelial
            splicing program essential for mammalian development
  JOURNAL   Elife 4, e08954 (2015)
   PUBMED   26371508
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4408)
  AUTHORS   Winkler,S., Mohl,M., Wieland,T. and Lutz,S.
  TITLE     GrinchGEF--a novel Rho-specific guanine nucleotide exchange factor
  JOURNAL   Biochem Biophys Res Commun 335 (4), 1280-1286 (2005)
   PUBMED   16112081
REFERENCE   6  (bases 1 to 4408)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   7  (bases 1 to 4408)
  AUTHORS   Yoshizawa,M., Sone,M., Matsuo,N., Nagase,T., Ohara,O., Nabeshima,Y.
            and Hoshino,M.
  TITLE     Dynamic and coordinated expression profile of dbl-family guanine
            nucleotide exchange factors in the developing mouse brain
  JOURNAL   Gene Expr Patterns 3 (3), 375-381 (2003)
   PUBMED   12799088
REFERENCE   8  (bases 1 to 4408)
  AUTHORS   Verdin,E., Dequiedt,F. and Kasler,H.G.
  TITLE     Class II histone deacetylases: versatile regulators
  JOURNAL   Trends Genet 19 (5), 286-293 (2003)
   PUBMED   12711221
  REMARK    Review article
REFERENCE   9  (bases 1 to 4408)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK129408.1, AK028648.1 and BC059220.1.
            
            Transcript Variant: This variant (3) differs in the 5' UTR and
            lacks two alternate in-frame exons in the 5' coding region,
            compared to variant 4. It encodes isoform c, which is shorter than
            isoform d.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK129408.1, SRR17784643.823027.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-687               AK129408.1         1-687
            688-1405            AK028648.1         698-1415
            1406-1416           AK129408.1         1406-1416
            1417-1675           AK028648.1         1427-1685
            1676-2208           AK129408.1         1676-2208
            2209-4179           AK028648.1         2234-4204
            4180-4408           BC059220.1         4285-4513
FEATURES             Location/Qualifiers
     source          1..4408
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 71.58 cM"
     gene            1..4408
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /note="Rho guanine nucleotide exchange factor 10-like"
                     /db_xref="GeneID:72754"
                     /db_xref="MGI:MGI:1920004"
     exon            1..123
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            124..203
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            204..389
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            390..423
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            424..515
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            516..599
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            600..769
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            770..878
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            879..985
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1063
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1243
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1360
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1453
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1627
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1628..1773
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..1955
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1956..2071
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2072..2199
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2200..2300
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2301..2422
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2509
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2510..2733
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2734..2888
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2889..3037
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3038..3212
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3213..3335
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3336..4382
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4151..4156
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /note="hexamer: CATAAA"
     polyA_site      4177
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
     regulatory      4360..4365
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4382
                     /gene="Arhgef10l"
                     /gene_synonym="2810441C07Rik"
                     /note="major polyA site"
ORIGIN      
        1 cgtgcggcgg ctgcaggccg cgggccgggg ctgcagtggg gcgcggggct cggcccggcc
       61 accggcgccc gcggcaggag cgggaggcgc ggtggcgcgg agcctttgtg agcagcgggg
      121 acggtgagca gcggggacgg tggtagactg agctggaccc tgtctgatgg cttcctcgaa
      181 ccctcctcca cagcctgcca taggagctcc cctggctccc agcgctccag gcccctcccc
      241 cgaggtggag gaggactccg gagaagcctt tgagtttgat gacagtgatg aggaggagga
      301 caccagctct ggcctggttg tccctggcct cgcccctgag agggacacag agccctcgct
      361 gatctgcttt gacactgtcc cgggctcaga cctggaccca gcagctgcac caccccagac
      421 agaggcaccc actgtggtca gcaatgggga tgcggtgggc gcagcgatct ctggggtccg
      481 gcgctccagc tggaagcgga agagctcacg tcgaattgac cgcttcactt tccctgccct
      541 ggaggaagat gtgatttatg acgacgtccc ctgtgagagc ccagacgccc atcagcccgg
      601 ggccgagcgg ggcctcgttt acgaggatgt gcatcgtgca ggagcaccgc gtgagaccga
      661 ggacctaggc tggagctcta gtgagtttga gagctacagc gaggactctg gggaggagac
      721 caaaccggag gccgagccca ctaagcaccg agggtccttc cagcccaaga tgacccagct
      781 catgaaggcc gccaagagcg ggaccaggga tgggctggag aagacccgga tggccgtcat
      841 gcgaaaagtc tcctttctgc ataggaaaga tgtcctcggt gactcagaag aagaagatat
      901 ggggctcctg gaggttggtg tgacagacat caaacctccc gcgccagagc tgggccccat
      961 gccggatggc ttgagtcctc agcaggtggt ccggagacac atcctaggct ccatcgtgca
     1021 gagcgaaggc agctacgtgg agtcactgaa gcggatactc caggattacc gtaacccact
     1081 aatggagatg gagcccaagg cgctgagcgc ccgcaagtgt caggtggtgt tcttccgcgt
     1141 gaaggagatt ctacattgtc actccatgtt ccagatcgct ctgtcctccc gcgtggccga
     1201 gtgggactcc acagagaaga ttggagacct ctttgtggct tcattctcca agtccatggt
     1261 cctagatgta tacagcgact atgtgaacaa cttcaccaac gccatgtcca tcatcaagaa
     1321 ggcctgtctc accaagccag cgttccttga gtttctcaag cggcggcagg tgtgcagtac
     1381 ggaccgagtc accctctatg ggttgatggt gaaacctgtt cagagatttc cacagttcat
     1441 cctcctactc caggacatgc tgaagaacac tccccggggc caccctgaca ggttgtcgct
     1501 gcagctagcc ctcacggagc tggagacgct ggctgagaag ctgaacgagc agaagcggtt
     1561 ggccgaccag gtggctgaga tccagcagct gaccaagagt gtcagtgacc gcagcagcct
     1621 caacaagctg ttgacctctg gccagcggca gctgcttctg tgtgagacac tgactgagac
     1681 ggtgtatgga gaccgagggc agctgatcaa gtccaaggag cgcagggtct tcctgctcaa
     1741 tgacatgctg gtctgcgcca acatcaactt caagggccag ctagagatca gcagcctggt
     1801 acctctgggg cccaagtacg tggtgaagtg gaacacagct ctgcctcagg tgcaggtggt
     1861 agaggtgggt caggatggtg gcacctacga caaagacaat ctgctcatcc agcatgctgg
     1921 agccaagaag gccactgctg cagggcaggc ccagaacaag gtgtacctgg gccccccacg
     1981 cctcttccag gagctgcagg acctgcagaa ggacctggcc gtggtggagc agatcaccct
     2041 cctcatcagc accttgcatg gcacttacca gaatctgaac atgactgtgg cccaagactg
     2101 gtgcctggcg ctgcagaggc tgatgcgggt gaaggaggag gagattcact cggccaacaa
     2161 gtgccgcctg aggctgctgc tccccgggaa gccagacaag tctggccggc ccatcagttt
     2221 catggtggtc ttcatcaccc cgaaccccct gagcaagatt tcctgggtca acagattaca
     2281 cttggcaaag attggactaa gggaggagaa ccagccagga tggctgtgtc ccgatgagga
     2341 caagaaaagc aaagccccgt tctggtgccc catcctggcc tgctgcgtcc ccgctttctc
     2401 ctcccggacc ctcagtctgc agcttggggg cctggtccac agtcctgtta actctcccct
     2461 gctgggcttc tcggcggtca gcacttccct tccacagggc tacctttggg ttggcggtgg
     2521 tcaggagggt gctggtggcc aggtggagat cttctccctg aaccggcctt caccgcgcac
     2581 ggtcaagtcc ttcccagtgg cggcccctgt gctctgcata gagtatattc cagatccgga
     2641 ggaggaggct gagggtgcag aggagagccg ggcagccacc gatccctcgg tcacagtgca
     2701 tcccactgtc tgccttggac tgcaggatgg cagcatccta ctgtatggca gtgtggacac
     2761 gggtacccag tgcctggcca cctgcaagag cccaggcccg cagcctgtgc tctgcctgcg
     2821 tcacagccct ttctacctgc ttgccggcct ccaggacggg accctcgctg cctatcctcg
     2881 gaccagtggt gacattccct gggacctgga gagccctccc atgtgcataa ctgtgggccc
     2941 agggccgatt cgaacactgc tgagcctgga agatgctgca tgggccagct gcgggccgag
     3001 ggtcactgta ctagatgccg ccactttgca aactcagcaa agcttcgagg cgcaccagga
     3061 tgaggcggtg agtgtcactc acatggtgaa agccggcagc ggtgtctgga tggccttctc
     3121 ctctggctct tccatccgcc tctttcacac ggagactctg gagcaccttc aggagatcaa
     3181 catcgccacc aggaccacct tcctcctgcc aggccaaaag cacctatgtg tcaccagcct
     3241 cctcatctgc cagggtctgc tctgggtagg cactgaccag ggtgtcattg tcctgttgcc
     3301 tgtaccccga ctggagggca tccccaagat cacagggaaa ggcatggtgt ctctcaatgg
     3361 tcactgtgga cctgtggcct tcctggctgt ggccatgagc atcctggccc ctgacatcct
     3421 gcggagtgac caggaagagg ccgagggacc gcaggccgag gaggacaagc cagacgggca
     3481 ggctcatgaa accgtgcctg ggcctgacag ccacacagct cgggagctga cccgcaagaa
     3541 aggcatcctg ctccaatacc gcctacgctc cacggcccac ctccccgggc ccctgttgtc
     3601 tgtgcgggag ccagcacctg ccgatggctc ggctctggaa cacagtgagg aggacgggtc
     3661 catctacgag atggccgatg accctgacgt ctgggtccgg agccggccct gtgcccgtga
     3721 tgcccaccgc aaggagatct gctctgtggc tatcatctct ggtggacaag gctaccgcca
     3781 tttcggcggt gctccaggtg gcctgagtgg gcgggcggcc ccgtgcagcg agacagacag
     3841 cacacttctc atctggcagg tgcccttggc tctatagctg tctaccctgc ccatccagag
     3901 gtcagggggc agctggatca ctgcggacat gctgggaccc tttggcccac ctggattttc
     3961 ctcagggacc tgcccaggcc acagggatag gcctggattc tccactgagg ccttggaaga
     4021 acagaggaga aacctctgga aaaaaattta gaatgtttgg ggaagggttt tttttagagt
     4081 cttgggggaa cggaaggata cacacagaga atatggccgt tttgttttgt tttgtttttg
     4141 aagcaaaaaa cataaaacct caccactgcc tgctgaacct agaacctttt gttggggctg
     4201 agtgaggctc cgaggtgggc gggcccctcc aggaggagtg tatgtgtgag tgtctgagcg
     4261 tgtgactata aatatatata tatataaata cgtatatacg atgtatatta tatgtatata
     4321 aatatgatct gtacataatg ggtctctggg agatgctgga ataaaaggca agttatatgt
     4381 ggaaaaaaaa aaaaaaaaaa aaaaaaaa
//
