LOCUS       NM_172739               8393 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus Rho GTPase activating protein 35 (Arhgap35), mRNA.
ACCESSION   NM_172739
VERSION     NM_172739.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8393)
  AUTHORS   Sharma,R., Kalot,R., Levin,Y., Babayeva,S., Kachurina,N.,
            Chung,C.F., Liu,K.J., Bouchard,M. and Torban,E.
  TITLE     The CPLANE protein Fuzzy regulates ciliogenesis by suppressing
            actin polymerization at the base of the primary cilium via p190A
            RhoGAP
  JOURNAL   Development 151 (6) (2024)
   PUBMED   38546045
REFERENCE   2  (bases 1 to 8393)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8393)
  AUTHORS   Li,Y., Chen,B., Zhao,J., Li,Q., Chen,S., Guo,T., Li,Y., Lai,H.,
            Chen,Z., Meng,Z., Guo,W., He,X. and Huang,S.
  TITLE     HNRNPL Circularizes ARHGAP35 to Produce an Oncogenic Protein
  JOURNAL   Adv Sci (Weinh) 8 (13), 2001701 (2021)
   PUBMED   34258149
  REMARK    GeneRIF: HNRNPL Circularizes ARHGAP35 to Produce an Oncogenic
            Protein.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8393)
  AUTHORS   Kaur,N., Han,W., Li,Z., Madrigal,M.P., Shim,S., Pochareddy,S.,
            Gulden,F.O., Li,M., Xu,X., Xing,X., Takeo,Y., Li,Z., Lu,K., Imamura
            Kawasawa,Y., Ballester-Lurbe,B., Moreno-Bravo,J.A., Chedotal,A.,
            Terrado,J., Perez-Roger,I., Koleske,A.J. and Sestan,N.
  TITLE     Neural Stem Cells Direct Axon Guidance via Their Radial Fiber
            Scaffold
  JOURNAL   Neuron 107 (6), 1197-1211 (2020)
   PUBMED   32707082
REFERENCE   5  (bases 1 to 8393)
  AUTHORS   Bonanomi,D., Valenza,F., Chivatakarn,O., Sternfeld,M.J.,
            Driscoll,S.P., Aslanian,A., Lettieri,K., Gullo,M., Badaloni,A.,
            Lewcock,J.W., Hunter,T. and Pfaff,S.L.
  TITLE     p190RhoGAP Filters Competing Signals to Resolve Axon Guidance
            Conflicts
  JOURNAL   Neuron 102 (3), 602-620 (2019)
   PUBMED   30902550
  REMARK    GeneRIF: p190RhoGAP is a critical regulator of motor axon guidance.
            Rather than acting as a compulsory signal relay, p190RhoGAP uses a
            non-conventional GAP-independent mode to transiently suppress
            attraction to Netrin-1 while motor axons exit the spinal cord. Once
            in the periphery, a subset of axons requires p190RhoGAP-mediated
            inhibition of Rho signaling to target specific muscles.
REFERENCE   6  (bases 1 to 8393)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   7  (bases 1 to 8393)
  AUTHORS   Hernandez,S.E., Settleman,J. and Koleske,A.J.
  TITLE     Adhesion-dependent regulation of p190RhoGAP in the developing brain
            by the Abl-related gene tyrosine kinase
  JOURNAL   Curr Biol 14 (8), 691-696 (2004)
   PUBMED   15084284
REFERENCE   8  (bases 1 to 8393)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 8393)
  AUTHORS   Brouns,M.R., Matheson,S.F. and Settleman,J.
  TITLE     p190 RhoGAP is the principal Src substrate in brain and regulates
            axon outgrowth, guidance and fasciculation
  JOURNAL   Nat Cell Biol 3 (4), 361-367 (2001)
   PUBMED   11283609
REFERENCE   10 (bases 1 to 8393)
  AUTHORS   Brouns,M.R., Matheson,S.F., Hu,K.Q., Delalle,I., Caviness,V.S.,
            Silver,J., Bronson,R.T. and Settleman,J.
  TITLE     The adhesion signaling molecule p190 RhoGAP is required for
            morphogenetic processes in neural development
  JOURNAL   Development 127 (22), 4891-4903 (2000)
   PUBMED   11044403
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147326.1, AK136766.1, AK032559.1 and AK137250.1.
            
            On Sep 14, 2006 this sequence version replaced NM_172739.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147326.1, AK147688.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7827              AK147326.1         1-7827
            7828-8133           AK136766.1         4506-4811
            8134-8370           AK032559.1         2887-3123
            8371-8393           AK137250.1         418-440
FEATURES             Location/Qualifiers
     source          1..8393
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.15 cM"
     gene            1..8393
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /note="Rho GTPase activating protein 35"
                     /db_xref="GeneID:232906"
                     /db_xref="MGI:MGI:1929494"
     exon            1..522
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /inference="alignment:Splign:2.1.0"
     exon            523..4394
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /inference="alignment:Splign:2.1.0"
     CDS             714..5213
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /note="P190 RhoGAP; glucocorticoid receptor DNA-binding
                     factor 1"
                     /codon_start=1
                     /product="rho GTPase-activating protein 35"
                     /protein_id="NP_766327.3"
                     /db_xref="CCDS:CCDS20851.1"
                     /db_xref="GeneID:232906"
                     /db_xref="MGI:MGI:1929494"
                     /translation="MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVR
                     PSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDD
                     QTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGF
                     LLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFAL
                     SKKNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDK
                     YEWLVSRIVKNHNENWPSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIE
                     RRRKLYLAALPLAFEALIPNLDEVDHLSCIKAKKLLETKPEFLKWFVVLEETPWDATS
                     HIDNMENERIPFDLMDTVPAEQLYETHLEKLRNERKRAEMRRAFKENLETSPFITPGK
                     PWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDRAKEEFQELLLEYSELFYELEL
                     DAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACV
                     DAKIEHLISSRFIRPSDRNQKNSLSDLNIDRINLVILGKDGLARELANEIRALCTNDD
                     KYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSR
                     ESTLGRRDNHLVHLPLTLILVNKRGDTSGETLHSLIQQGQQIASKLQCVFLDPASAGI
                     GYGRNINEKQISQVLKGLLDSKRNLNLVSSTASIKDLADVDLRIVMCLMCGDPFSADD
                     VLSPVLQSQTCKSSHCGSSNSVLLELPIGLHKKRIELSVLSYHSSFSIRKSRLVHGYI
                     VFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDGAIDVLDNDLSREQLTEGEEIAQE
                     IDGRFTSIPCSQPQHKLELFHPFFKDVVEKKNIIEATHMYDNVAEACSTTEEVFNSPR
                     AGSPLCNSNLQDSEEDVEPPSYHLFREDATLPSLSKDHSKFSMELEGNDGLSFIMSNF
                     ESKLNNKVPPPVKPKPPVHFDITKDLSYLDQGHREGQRKSMSSSPWMPQDGFDPSDYA
                     EPMDAVVKPRNEEENIYSVPHDSTQGKIITIRNINKAQSNGSGNGSDSEMDTSSLERG
                     RKVSAVSKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGYKGDNAV
                     IPYETDEDPRRRNILRSLRRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTPEKPIP
                     IFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGA
                     MKSFFSELPDPLVPYSMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISH
                     LNKVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATRSYQTIIELFIQQCPFFF
                     YNRPISEPPGAAPGSPSAMAPTVPFLTSTPATSQPSPPQSPPPTPQSPMQPLLSSQLQ
                     AEHTL"
     exon            4395..4539
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /inference="alignment:Splign:2.1.0"
     exon            4540..4617
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /inference="alignment:Splign:2.1.0"
     exon            4618..4749
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /inference="alignment:Splign:2.1.0"
     exon            4750..4855
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /inference="alignment:Splign:2.1.0"
     exon            4856..8393
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7804..7809
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /note="hexamer: AATAAA"
     polyA_site      7829
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
                     /note="major polyA site"
     polyA_site      8308
                     /gene="Arhgap35"
                     /gene_synonym="6430596G11Rik; Grlf1; mKIAA1722; p190A;
                     p190RhoGAP"
ORIGIN      
        1 ggtgtccgcg cgtgcctgtc ctcccggcct acggtcctcg cggtgcgctc ggcccacagg
       61 gccgttatcc acttcccaac cccagcccca gcatctctcg cccctcagaa acgcacgcgc
      121 acttgcgaga gggtctccag tacgcgcacg gccgcggcgg ccgcaggaag gaggcgacaa
      181 cgccgctgcc gccgccgccg ccgccgccgc cattgcgcgg gagggaggga acgagcgagc
      241 gagcgaggct ggtccgccct ccccctggtt cccgcccctc cccccttccc ctccccgccc
      301 cccgccccga gggagagccg cggcgcggcg ggaggaggag gtggaggagg cggaggaggg
      361 agcccgcgag ggagggtccg cccggccccc cgccgccgga gccgccaccg ccgcctcagc
      421 cgcctcagga acgagtcgct aggggaacat ggcgccgggc ccgccgtcgc tgcggctggg
      481 atcgcggagg ccggggccgc gctgagtgcg cccccgagac tggcagacat gttggctatt
      541 tggcgatgag aagtttgaag aactgacatc atactggttt agaacactat gggacctgac
      601 atttgcgctg cttgggcagc cagtgcccat tggtactgct aagaagccct cactctactg
      661 cagaacacta atctgatctt ggaagtggct gattgtggca ggatgtttcg aagatgatga
      721 tggcaagaaa gcaagatgtc cgcatcccca cctacaacat cagtgtggtg ggattgtcag
      781 gcactgagaa ggagaaaggc cagtgcggca ttgggaagtc ttgtctgtgt aaccgctttg
      841 tgcgcccaag tgctgatgag tttcacctgg accacacttc tgtccttagc accagtgact
      901 ttggtgggcg ggtggtcaat aatgaccact ttctgtactg gggagaagtt agccgctccc
      961 tggaggattg tgtggaatgt aagatgcaca ttgtggagca gactgagttt attgacgatc
     1021 agacttttca acctcatcga agcacggcac tgcagcccta catcaagaga gccgcagcca
     1081 ccaagcttgc ttcagctgaa aaactcatgt atttttgcac tgaccagctg ggactggagc
     1141 aagactttga gcagaaacag atgccagatg ggaagctgct ggttgacggt ttccttctgg
     1201 gcattgatgt tagcaggggc atgaacagga acttcgatga tcagctcaaa tttgtctcca
     1261 atctctacaa tcagcttgca aaaacaaaaa agcccatagt ggtagtcctg actaagtgtg
     1321 atgagggcgt tgagcggtac attagagatg cacatacttt tgccttaagc aaaaagaacc
     1381 tccaggttgt agagacctct gcaaggtcca atgtgaatgt ggacttggct ttcagcacct
     1441 tagtgcaact cattgataag agtcgaggga agacaaaaat catcccttac tttgaagctc
     1501 tcaagcagca gagtcagcag atagctacag caaaggacaa gtatgagtgg ttagtgagcc
     1561 gcattgtgaa aaatcacaat gagaactggc cgagtgtcag ccgaaagatg caggcctccc
     1621 ctgagtacca ggactatgtc tacctggaag ggacacagaa ggccaagaag ctcttcctgc
     1681 agcacattca ccgcctcaag catgagcata ttgagcgtcg gagaaagctg tacctggcag
     1741 ctctgccatt ggcttttgaa gccctcatac ctaatctaga tgaagtggac cacctgagct
     1801 gtattaaagc aaaaaagctg ttagagacca agccagagtt cttaaagtgg tttgttgtac
     1861 ttgaagaaac accatgggat gccaccagcc acattgacaa catggaaaat gagcggattc
     1921 cctttgactt gatggatact gtccctgctg agcagttgta tgagacccac ttggagaagc
     1981 tgaggaacga gaggaagaga gctgagatgc gaagggcttt caaagaaaac ctggagacct
     2041 ctcctttcat aactcctggg aaaccttggg aagaagctcg tagttttatt atgaatgaag
     2101 acttctacca gtggctggaa gaatctgtgt acatggacat ctatggcaag caccaaaagc
     2161 agattataga ccgagcaaag gaagagttcc aagagttgct tttggagtac tcagaattgt
     2221 tttatgagct ggagctggac gctaagccca gcaaggagaa gatgggtgtc atccaggatg
     2281 ttctgggcga agagcagaga tttaaagcat tgcagaagct ccaagcagag cgtgatgccc
     2341 tcattctgaa gcacatccat tttgtgtacc acccgacgaa ggagacatgc ccaagctgtc
     2401 cagcttgtgt agatgctaag attgaacact tgatcagttc tcgctttatc agaccatctg
     2461 atcggaatca gaagaactct ctgtctgacc tcaatattga taggatcaat ttggttatct
     2521 taggcaaaga tggccttgcc cgagagttgg ccaatgaaat tcgagctctt tgtacaaatg
     2581 atgacaagta tgtaatagat ggtaaaatgt atgagctttc tctgaggcca atagagggga
     2641 atgtccggct tcctgtgaac tctttccaga caccaacctt ccaaccccat ggctgtctct
     2701 gcctttacaa ttcaaaggag tcactgtcct atgtggtgga gagtatagag aagagcagag
     2761 agtctacact gggcaggcgg gataatcatt tagtccacct tcccttgacc ttaattttag
     2821 ttaacaagag aggggacaca agtggagaga ctctgcacag cttgatacag caaggtcagc
     2881 agattgccag caaacttcag tgtgtctttc ttgatccggc ttctgctggc attggttatg
     2941 gacgcaacat taatgagaag cagatcagtc aagttctgaa aggactcctg gactccaagc
     3001 gcaacttaaa cctggttagc tccactgcaa gtatcaaaga tttggctgat gtggaccttc
     3061 gaattgtcat gtgtctgatg tgtggtgatc cctttagtgc agatgacgtt ctctctcctg
     3121 tcctgcaatc ccaaacttgt aaatcttccc actgtgggag cagcaactct gttttacttg
     3181 aacttccaat tggactacac aagaagcgca ttgagctgtc tgttctttca taccattcct
     3241 catttagcat ccgaaagagc cggttggttc atgggtacat tgttttttat tcagccaaac
     3301 gtaaggcctc cttggcaatg ttacgtgcct ttctttgtga agtgcaggat attatcccca
     3361 tccagcttgt cgcactcact gatggcgcta tagatgtcct agacaatgac ttaagtcgag
     3421 agcagctaac agagggagag gaaattgcac aagagattga cgggagattc acaagcatcc
     3481 cttgtagcca gccccagcat aaacttgagc tctttcatcc cttttttaaa gatgtggtgg
     3541 agaaaaagaa cataattgag gccacacata tgtatgataa tgtagctgag gcctgcagca
     3601 ccactgagga agtgttcaac tcccccagag ctggctcacc cctctgcaac tcaaacttac
     3661 aggactcaga agaagatgtg gagcctccat cataccacct gtttcgggaa gatgcgacat
     3721 tgccctccct gtccaaagat cattccaagt tctctatgga actggaggga aatgacgggc
     3781 tatctttcat aatgagcaat tttgagagta aactgaacaa caaagtacct cccccagtca
     3841 aaccaaagcc tcctgtgcat tttgatatca caaaagatct ttcttactta gaccaaggcc
     3901 atcgggaggg acagaggaaa tctatgtctt ctagcccctg gatgcctcag gatgggtttg
     3961 atccttctga ctacgcagag cccatggatg ctgtggtcaa gccaaggaat gaggaagaaa
     4021 acatatactc ggtgccccac gacagcaccc agggcaagat cattaccatt cggaacatca
     4081 acaaagccca gtccaatggc agtggtaatg gttctgacag tgagatggac acaagttccc
     4141 tagagcgagg ccgcaaggta tctgcagtga gtaagcctgt gctgtacagg acaagatgca
     4201 ctcgcctggg gcggtttgct agttaccgta ccagcttcag tgtcgggagt gatgatgagc
     4261 tgggacccat ccgaaagaaa gaggaggacc aggcatccca aggttataaa ggggacaatg
     4321 ctgtcattcc atatgaaaca gatgaggacc ccaggaggag gaatatcctt cgaagtctaa
     4381 gaaggaacac caagaaacca aagcccaaac cccggccatc catcacaaag gcaacctggg
     4441 agagtaacta ttttggggtg cccttaacaa cagtggtgac tccagagaaa ccgataccca
     4501 ttttcattga aagatgcatt gagtacatcg aagccacagg actaagcact gaaggcatct
     4561 accgggtcag tggaaacaag tcagaaatgg aaagtttgca aagacagttt gatcaagacc
     4621 acaatctgga cctggcagag aaagacttca ctgtgaacac tgtggcaggg gccatgaaga
     4681 gttttttctc agagctacca gaccccctgg taccatacag catgcagatt gacttggtgg
     4741 aagctcacaa aatcaacgac agggaacaga agctgcatgc tctgaaggaa gtgctgaaga
     4801 agttcccgaa ggaaaaccat gaagtcttca aatatgtcat ctcccacctg aacaaagtca
     4861 gccacaacaa caaggtgaat cttatgacca gtgagaacct gtccatctgc ttctggccca
     4921 cgctgatgcg gcctgacttc agcagcatgg acgcgctcac agccacgcgc tcctaccaga
     4981 ccatcatcga gctcttcatc cagcagtgcc ccttcttctt ctacaaccgg cccatcagcg
     5041 agcctccagg ggctgcgcct ggctcccctt cagccatggc tcccactgtt cccttcctca
     5101 cctctacacc tgctaccagt cagccatcac ctccccagtc acctcctcca acccctcagt
     5161 ccccaatgca gccattgctg tcctctcagc tccaagccga acacacgctg tgagccacca
     5221 cagcccagga agcaggaaaa ccaatcgtct tcttgacagg gtggcatttg gccttgaaca
     5281 aaatcaggtc ccctggggtg gaagtcacag ccaagcgcct ttttaagact tgagtggtgg
     5341 cactagccag tgtcccccat ggctgggcag ttgagcacct gctcttcacc tgccctggct
     5401 atggctgtgg caagctgtga gccctcgcct tgtctgggcc aatctgagga ctgaactgac
     5461 cagatagcgg ccccatcacc cctactgctc cttggacccc ttggcccaac ctgtctgcct
     5521 gcaccagcgt caggccccac catcgggaca tcaccccagc ctctgccagg ggcagaggta
     5581 accccaagca gggctggccc ctctaaagag gacatttccc agtttgtcct ttcttgtcca
     5641 tacctacaca cacctgcagc gggggtctgg ggaacatgtg ggctatggct ctgctacccc
     5701 gtaggacaca ctgggtcact ggcatggccc aacagcacag caagaggaga gctttgtgcc
     5761 tatacccagt gtgtggcttt cctccaaccc cttcccagac ttgtgatcca ttccctgcag
     5821 caaaggaaca ctggaagaaa gatggagctc ctccacagag acagaaagaa accacagcaa
     5881 gaaaacagac ctcaagtttc cactctgacc tgccaggtgg ccactgggta aacaagtcct
     5941 tttgtctatg tatgacagca aagcaaggac acctgggcag taactgcaac cacagccccc
     6001 tccccccact ccctaagaac acagcccttg gaaggattgt tagcatggcc cccacccctc
     6061 ctgccaacca gcacactaca tacactacta tagaaacact acaggtgtgt gcacacagca
     6121 ctcaggttgg catgtttggt gttgaaatgg ggtcatttca ttccatgtta tgaatgcaac
     6181 cagaaagggt gtctgggata tgagcagatg tggcatcttc cagaaatgat catctggtta
     6241 tggaatgaag ggacctgttc tcaagcaaag gtcatcacag tgacccaacc cagacacttc
     6301 cccagcagcc tccccatact ctgctcctga tgtggcaacc cttgtcggct cctgcctttg
     6361 ccccccactt taatctaagc actgggccat gaaatctgac actaaggtac cctgagcata
     6421 ggaggggcat gggtcgcacc attgcacttt agaaataaca cggagtgttc ccaagggcct
     6481 caggtggact gccaccctgc ctttatctct gtaggataag aggaggatga ctggcctctg
     6541 gcccaggtcc tggctgtctc cctatctcta atacttggca acataaggtg cttgcaaaca
     6601 ctaaggctgc cccctgcaaa gtaaactcca agacaaacca aacccaaggt acaaatgtgt
     6661 tacacataaa tgttttcctt cctgggggtc tgtgttggat gttgtgggcc tggagtcaat
     6721 aggaacatac aatgtgtgta gtgtccgcta aggttgcagt tggtcccctg ccctgacttc
     6781 atgccccaag cctcagctat tggaatggct tccattcagt agcttctgtg ttggtccttt
     6841 gtagagatgg aagtggagcc atcctgctgt gaacagttat gaaccagggg aggctgctgc
     6901 atgtgcctat tatgttggca gtgggtggca ggcagaggca ggcacgcgat tagtagagcc
     6961 ctgcttgggc ctcactttgt ggacaccagg ctggtgcacc tcccttttca ggcactctga
     7021 gtgtccttcc cacccatgac aaggcaacca cagaagtcag aacaatcagg cttgagtggg
     7081 tggccaggtc agctactgcc cttcccagaa agccctggag gtgaccatag cctgtcacca
     7141 cccaacatca ccacgggctg ggttttgtgt ttcacattgg gtagtatgca ttctgtctgc
     7201 actgtcccac cttctcatct ctacctttta agggatatgg aaaggtctgg agctctgtct
     7261 gaccccacac tctccatttt ccccagccaa ggcagacagc agcactagca gacggtctta
     7321 gaaccttcac actgtctcta ccactacatg gaatgacata aaagcaactt gtaggccaga
     7381 ggggtggggt gaacccttct gtggtctgta cccctggtct agtgggagga atccctgaag
     7441 acctgcatcc cctaagtgag gaccctacag ggtaccttgt gctctgcccc cagacccata
     7501 gccttagcag tgggccaact acaatcctca tctcctaaag tcatctacag atggcaggtg
     7561 gaagaaagtg gttctccatt ccacatccac tgccagtgtg catggggagg gcaggggatg
     7621 gactgggtca ctctaggact gcagcagcca gggacactgt agagaggcta aggctagagg
     7681 cactattacc caaccatgaa gccacccaag tagtggagcc aggacataag ttattgttca
     7741 cattaaagaa tcatgttccc tgtgtacatt ttaagcaaag gaaaagtctt gggattgtat
     7801 gggaataaaa cttgtttgaa aatttggaat agtgctgctg tcagcttatt tttctggtac
     7861 ttgtattttc tatgttaaat gatctttata tgtgttggat taacaaatat tttgagtttc
     7921 ctgaaaacaa acagaaacat taatggtatt gaagtgtgtt agtagtctgg ccgtgtgccc
     7981 aaacttatgt ttcgcagcaa aagtggaaac ctgtctgtaa agcaagtgta acgatgattt
     8041 cctgtatcat gggggctcaa accaggacct ctctagttgc tgttaggaat gtctgcttca
     8101 tttccaagct tttttttttt tttttttttt tttttaaata cgtcatgggt ttctgaggct
     8161 ccagcctgtt tagtgcatgg gcagccatcc tggcagccaa gacatctctg acagaagtgt
     8221 ttttgtttgg ttttgttttt taagattatg tatttgctac aaagtattgt acttgtctca
     8281 atgggaatgg tgttaaaaaa gaaaaaaaga cagaaaaggc cttatgtgat atgtatcata
     8341 gttaataaat caatcttgta aaaaaaaaaa ccataaataa aaacaggcct gag
//
