LOCUS       NM_001005508            4509 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus Rho GTPase activating protein 30 (Arhgap30), mRNA.
ACCESSION   NM_001005508 XM_129550
VERSION     NM_001005508.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4509)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4509)
  AUTHORS   Butterfield,N.C., Curry,K.F., Steinberg,J., Dewhurst,H.,
            Komla-Ebri,D., Mannan,N.S., Adoum,A.T., Leitch,V.D., Logan,J.G.,
            Waung,J.A., Ghirardello,E., Southam,L., Youlten,S.E.,
            Wilkinson,J.M., McAninch,E.A., Vancollie,V.E., Kussy,F.,
            White,J.K., Lelliott,C.J., Adams,D.J., Jacques,R., Bianco,A.C.,
            Boyde,A., Zeggini,E., Croucher,P.I., Williams,G.R. and
            Bassett,J.H.D.
  TITLE     Accelerating functional gene discovery in osteoarthritis
  JOURNAL   Nat Commun 12 (1), 467 (2021)
   PUBMED   33473114
  REMARK    Erratum:[Nat Commun. 2021 May 28;12(1):3302. doi:
            10.1038/s41467-021-23768-8.. PMID: 34050183]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4509)
  AUTHORS   van der Weyden,L., Swiatkowska,A., Iyer,V., Speak,A.O. and
            Adams,D.J.
  TITLE     A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators
            of Pulmonary Metastatic Colonisation
  JOURNAL   G3 (Bethesda) 10 (6), 1869-1877 (2020)
   PUBMED   32245826
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4509)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY740863.1, BC082573.1 and AK031319.1.
            
            On May 8, 2009 this sequence version replaced NM_001005508.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082573.1, AK031319.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                BY740863.1         8-59
            53-1386             BC082573.1         1-1334
            1387-2216           AK031319.1         1158-1987
            2217-4509           BC082573.1         2165-4457
FEATURES             Location/Qualifiers
     source          1..4509
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 79.39 cM"
     gene            1..4509
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /note="Rho GTPase activating protein 30"
                     /db_xref="GeneID:226652"
                     /db_xref="MGI:MGI:2684948"
     exon            1..404
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     CDS             308..3589
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /note="rho-type GTPase-activating protein 30"
                     /codon_start=1
                     /product="rho GTPase-activating protein 30"
                     /protein_id="NP_001005508.2"
                     /db_xref="CCDS:CCDS15494.1"
                     /db_xref="GeneID:226652"
                     /db_xref="MGI:MGI:2684948"
                     /translation="MKSRQKGKKKGSSKERVFGCDLREHLQHSGQEVPQVLRSCAEFV
                     QEYGVVDGIYRLSGVSSNIQKLRQEFETERKPDLRRDVYLQDIHCVSSLCKAYFRELP
                     DPLLTYRLYDKFAEAVAVQLEPERLVKILEVLQELPIQNYRTLEFLMRHLVHMASFSA
                     QTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFRGD
                     SLSAGVDLESGWKSLPGARASGSSEDLMPTSLPYHLPSILQAGDGPPQIRPYHTIIEI
                     AEHKRKGSLKVRKWRSIFNLGRSGHETKRKLPLRVEDREEKSSKGTLRPAKSMDSLSA
                     AAGASDEPEGLVGSSSSQPSSLMPESLESNSMEGEQEPEAEAPGSANSEPGTPRAGRS
                     AVRALGSSRAERCAGVHISDPYNVNLPLHITSILSVPPNIISNVSLVRLTRGLECPAL
                     QPRPSPALGPGPPDEKSEARSVPGPLDDSSPAAMTPALEDSLSQEVQDSFSFLEDLSS
                     SEPEWVGVEEREVAKAEAAGAAGAAAFSLGEDDPGMGYLEELLRVGPQVEEFSVEPPL
                     DDLSLDDTQYVLAPNCCSLDSAVSTPDVEEDYGEEVFLSAYDDLSPLLGPKPINWEGV
                     GSLEEEAAGCGKQPPTQDEEEQACSETRQEKEAKPRSTSDNREEAEATPETEMEAGKA
                     DAEGGEAERSQKVMDSFKEGSREELEAKEENSEGREVESIKETKDVEKIIGEPGKDEE
                     REIGREEGAEKGDDTPVDSDMDPEHVFQEDLVLEESWEVVHKHEAEKGRESETKELRR
                     KSDLKSREDQGHSEDSGSPEEGDDRKEGVFSKEQKSIDVETEVMRGVGDHLEEGALSE
                     GPGVELLRVDSTEEINEQTSEMKQAPLQPSEPEGMEAEGQLNPETCDLYSCPCGSAGG
                     VGMRLASTLVQVRQVRSVPVVPPKPQFAKMPSAMCSKIHVAPASPCPRPGRLDGTPGE
                     KAWGSRASWRNGGSLSFDAAVALARERQRTESQGVLRTQTCTGGGDYSLSSRTPPCSM
                     ILAHSSRPLSCLERPPEGTEGSEPRSRLSLPPRELHPVVPLVAPQRQTYAFETQTNHG
                     KDEGV"
     exon            405..507
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            508..652
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            653..735
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            736..843
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            844..971
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1146
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1250
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            1251..1328
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1697
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..1975
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     exon            1976..4488
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4456..4461
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /note="hexamer: AATAAA"
     polyA_site      4488
                     /gene="Arhgap30"
                     /gene_synonym="6030405P05Rik; Gm102; mFLJ00267"
                     /note="major polyA site"
ORIGIN      
        1 gaggagctgc acagcttcct gctccccctc gagctgcaca ggacgagaag ggctagcgct
       61 cagcttggcc acgagacaca gcttcatgcc agggttctgg tagcttcctc ttccatatct
      121 acttccgtgt ggccccaggg gccccccaga ggcaagcgct gctgtccctt gcccaggcca
      181 ccctccacct ccagtttgga gccctgcccc ccctggggct gggccaagcc caactactga
      241 ctgggattcc atgggggact ggtaggtcaa aggtcttggg ggacagagat cccggggggc
      301 cctggtcatg aagtctcggc agaaaggaaa gaagaagggc agctctaagg aacgggtgtt
      361 tgggtgtgac ctacgtgagc atctacagca ctcgggccag gaagtgcccc aggtgctacg
      421 gagctgtgca gagtttgtgc aagagtatgg agtggtggat gggatctacc gcctctcagg
      481 ggtctcctct aacatccaga agctccggca ggagtttgag acggagcgga agccagacct
      541 gcgccgggat gtttatctcc aggacattca ctgcgtctct tccttgtgca aggcctactt
      601 cagagaactc ccagatcccc tcctcactta tcggctctat gacaagtttg ctgaggcagt
      661 ggccgtgcag ctagagccag agcgattggt caagatccta gaagtgcttc aagaactccc
      721 tatccaaaac tacaggaccc tggaattcct tatgcgccac ttggtccaca tggcctcatt
      781 tagtgcccaa accaacatgc atgctcgcaa tctggcaatt gtgtgggccc ccaacctgct
      841 gaggtctaag gacatagagg cctcaggctt caatgggaca gcagcgttca tggaggttcg
      901 agtgcagtcc attgttgtgg agttcatcct tacccatgtg gaccagctct ttaggggtga
      961 ctccctctct gctggtgtag acttggagag tggatggaaa tcacttccag gagcccgggc
     1021 atcaggcagc tccgaggacc tcatgcccac ctctcttccc taccacttgc ccagcatctt
     1081 gcaggctggg gatggacctc cacagatccg accctaccat actattattg agattgcgga
     1141 acacaagaga aaggggtcat tgaaggtcag gaaatggcgc tctatcttca atttgggtcg
     1201 atctggacac gagacaaaac gtaaacttcc gctgagggtt gaggacaggg aagaaaaatc
     1261 cagtaagggg acactgcggc ctgccaaaag catggactcg ctgagtgctg ccgctggggc
     1321 cagtgacgag ccggaggggc tggtggggtc cagcagttct cagccaagct cactgatgcc
     1381 tgagagcttg gagagtaatt ctatggaagg tgaacaggag cctgaagcag aggcaccggg
     1441 cagtgccaat tctgagccgg gaactccacg agccgggcga tcagctgttc gggccttagg
     1501 tagcagtaga gcagagcgtt gtgctggtgt ccacatctca gacccttaca acgtcaacct
     1561 ccctctgcac ataacctcca tcctcagtgt tcctccaaac atcatctcta atgtctcctt
     1621 ggtcaggctc acccgaggcc ttgagtgccc tgccctacaa ccccggccaa gccctgcctt
     1681 gggtcctggc cccccagatg agaaatcaga ggcaagatca gtcccaggtc ccctggatga
     1741 ctcgagccct gcagccatga ctcctgccct agaggactcc ctgtcccagg aagtgcagga
     1801 ctccttctcc ttcctagagg atttgagcag ctcagagcct gagtgggtgg gggtggagga
     1861 gagggaggtg gccaaggcag aagccgcagg agcagcagga gcagcagctt tctcccttgg
     1921 ggaggacgac cctgggatgg gctacctgga ggagctgctg agagttgggc ctcaggtaga
     1981 agagttctct gtggagccac ccctggatga cctgtctctg gatgatactc agtatgtcct
     2041 ggctcctaac tgctgctccc ttgattctgc ggtttccaca cctgacgtag aagaggacta
     2101 tggggaagaa gtcttcttga gtgcctatga tgatctgagt ccccttctgg ggcctaaacc
     2161 catcaactgg gaaggtgtag ggagtctgga ggaagaggca gcagggtgtg ggaaacaacc
     2221 tccaacacag gatgaagaag aacaggcctg ctcagaaacc aggcaggaaa aggaggctaa
     2281 gccccggagc acatcagata accgggaaga agcagaggca actccagaga ctgagatgga
     2341 ggctggaaag gctgatgcgg aaggagggga ggctgagaga agccaaaagg tgatggatag
     2401 ttttaaagaa gggagtaggg aagagctaga ggccaaggaa gaaaattccg aaggtcgaga
     2461 ggttgaaagt ataaaggaga ccaaggatgt ggaaaaaata ataggagaac cgggtaaaga
     2521 tgaggagaga gagattggga gagaagaagg agctgagaaa ggagatgaca ccccagtaga
     2581 ctctgatatg gatccagagc atgtgttcca ggaagacctg gttcttgagg agagctggga
     2641 agttgtccac aagcatgagg ctgagaaagg cagagagagt gagaccaaag agctgaggag
     2701 gaagagtgac cttaagtcaa gagaagacca aggacacagt gaagacagtg gaagtccaga
     2761 agagggtgat gataggaagg aaggggtttt cagcaaggaa caaaaaagta tagacgtaga
     2821 aactgaagtc atgagaggtg ttggtgacca cttagaagag ggggccctct ctgaagggcc
     2881 aggtgtcgag ttactgaggg ttgacagtac agaagaaatc aatgaacaga cctctgagat
     2941 gaaacaagcc ccgctacagc catctgaacc agagggcatg gaggctgagg gacagcttaa
     3001 tcctgagaca tgtgacctgt attcttgtcc ctgtgggtca gctggtggtg tgggcatgcg
     3061 tctggcttcc accctagttc aggtccgaca ggtccgctct gtccctgtag tgccccccaa
     3121 accacagttt gccaagatgc ccagtgcaat gtgtagcaag atccatgtag cacctgcaag
     3181 cccatgtcca aggcctggta ggcttgatgg gactcctgga gaaaaagctt ggggttctcg
     3241 agcttcctgg aggaatgggg gcagtctttc ttttgatgct gctgtggccc tggcccggga
     3301 acgccagagg accgagtctc agggagttct gcggacccag acctgtactg gaggtgggga
     3361 ttatagtctc agctccagaa cccctccttg tagcatgatc cttgcccatt cttcccggcc
     3421 ccttagctgt ttggaacgcc cacctgaagg cacagagggg tctgagccca ggagtcggct
     3481 tagtctgccc cctagagagc ttcaccctgt tgtccctctt gtggcccctc agcgccagac
     3541 atatgctttt gaaacacaga ctaatcatgg gaaagatgaa ggggtatgat taggacagga
     3601 caagaggaac caagaaatca tcaccaatct ctggagcact tgcctagctg tctttgctgc
     3661 ctcggcagct gagatgtcta attccatagg cttgggtcct ccagcttctt gttttgacca
     3721 tgagaggtac agacttggtg gatttactta tgtttgtgtt agacacaaag ccacttatgt
     3781 cttagcagag tcttaagaaa catagaacaa tcttgtttcc agggagttaa caaaaacata
     3841 gggtaggtaa aagctttttt ttttcttaaa tttaaataca gtgggggaat ttcagccaaa
     3901 cttttgccct attctgagct gtgaatatct cttcacagaa gcctactgta gatgtgggag
     3961 atataggacc agatatagaa tagctcaccc ctgatttgtt cctagatttt tggctgtctt
     4021 ctgaccctct ttagtttcag agtaggagaa acatccaaga agctctttaa agtcctcagt
     4081 gtttgctgaa ggaaatgggt ggcatcctct accttcaatt attttgcaga agaggtcctc
     4141 ccattttagg aaaagggaat gttgggctga agagatagct cagaggttaa gagcacctac
     4201 tgttcttcca gaggtcctga gttcaattcc tagcaatcac atgatggctc acaaccatct
     4261 gtaacggaat ttgatgcctt ctacgggtga gtctgaagag agcaatggtg tactcattca
     4321 tatacataaa ataaataaag aaagaaaaga aaaaggaaaa gaaaagtaga gggaatgtca
     4381 ctcaatttgg ctctagcact gtctctgcac aggctggggc tacaggccac catttagcaa
     4441 tggtgggtat ttgataataa aagctgaatt ttttttttaa catttaaaaa aaaaaaaaaa
     4501 aaaaaaaaa
//
