LOCUS       NM_021493               5450 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus Rho GTPase activating protein 23 (Arhgap23), mRNA.
ACCESSION   NM_021493 XM_977838
VERSION     NM_021493.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5450)
  AUTHORS   Jiang D, Burger CA, Casasent AK, Albrecht NE, Li F and Samuel MA.
  TITLE     Spatiotemporal gene expression patterns reveal molecular
            relatedness between retinal laminae
  JOURNAL   J Comp Neurol 528 (5), 729-755 (2020)
   PUBMED   31609468
REFERENCE   2  (bases 1 to 5450)
  AUTHORS   Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK,
            Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L,
            Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre
            JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A,
            Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ,
            Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall
            S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA,
            Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR,
            Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana
            S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, MacArthur DG,
            Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC,
            Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL,
            de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown
            SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M and Murray
            SA.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   3  (bases 1 to 5450)
  AUTHORS   Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H,
            Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T,
            Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P,
            Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ,
            Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD,
            Flicek P, Skarnes WC, Mallon AM and Parkinson H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 5450)
  AUTHORS   Okazaki N, F-Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S,
            Saga Y, Seino S, Nishimura M, Kaisho T, Hoshino K, Kitamura H,
            Nagase T, Ohara O and Koga H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   5  (bases 1 to 5450)
  AUTHORS   Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng
            EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC,
            Babbitt PC and Ferrin TE.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ115457.1, BU505571.1, BU708895.1, BQ444174.1, CB525670.1,
            CX243267.1, BM943900.1, BI739912.1 and AK173187.1.
            
            [WARNING] On Mar 22, 2024 this sequence was replaced by
            NM_021493.3.
            
            On Sep 19, 2006 this sequence version replaced NM_021493.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-114               CJ115457.1         1-114
            115-760             BU505571.1         1-646
            761-1352            BU708895.1         1-592
            1353-1457           BQ444174.1         1-105
            1458-1859           CB525670.1         1-402
            1860-2111           CX243267.1         1-252
            2112-2247           BM943900.1         278-413
            2248-2354           BI739912.1         1-107
            2355-5450           AK173187.1         1-3096
FEATURES             Location/Qualifiers
     source          1..5450
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 60.97 cM"
     gene            1..5450
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /note="Rho GTPase activating protein 23"
                     /db_xref="GeneID:58996"
                     /db_xref="MGI:MGI:3697726"
     exon            1..206
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            207..1359
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             342..4175
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /note="rho-type GTPase-activating protein 23"
                     /codon_start=1
                     /product="rho GTPase-activating protein 23"
                     /protein_id="NP_067468.2"
                     /db_xref="CCDS:CCDS36293.1"
                     /db_xref="GeneID:58996"
                     /db_xref="MGI:MGI:3697726"
                     /translation="MVPEPISALPPDPRSPAAWSDPGSRVPSATRAHLDNSSLGMSQP
                     RPSPGAFPHLPSESRTPRAFPEPGSRVLPSRLECQQALSHWLSNQIPRRAGERRCPAM
                     PPRARSASQDRLEDVTTHHPWPCSTSQDALSQLGQEGWHRARSDDYLSRATRSAEALG
                     PGALVSPRLERCGWASQRPSARTSACPSRDLTQAPPPSGLQGLDDIGYIGYRSYSPSF
                     QRRTGLLHALSFRDSPFGGLPTFSLAQSPASFPPEASEPPRVVRPDPSTRALEPPAED
                     HRDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEARGERLGRKVAPLATTEDSLA
                     SIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFALSRHYSQDCS
                     SIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPSRVPSLRVLRSFFTDGSL
                     DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGGGLRQWKRV
                     YAVLRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVF
                     RLTTADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSH
                     SSGPKADSSPKGSRGLGGLKSEFLKQTAVRGLRTQEQPPGSKEDSVAAPKTPWGINII
                     KKNKKAAPRAFGIRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVV
                     SSLQEQLNRGPSDINLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIE
                     DSRERMKTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVR
                     TSEDNMTDMVTHMPDRYKIVETLIQHSDWFFSDDEDKGERTPVDDKEPQSVPNIEYLL
                     PNIGRTVPPSDPGSDSTTCSSAKSKGSWVPKKEPYAREMLAISFISAVNRKRKKRREA
                     RGLGSSTDDDSEQEAHKAAVGTQEPPEGQLPGPAAEEAPGRLSPPTAPDERPAADTRS
                     IVSGYSTLSTMDRSVCSGTGGRRAGAGDEADDERSELSHVETDTEGGAGPGGRLSRRP
                     SFSSHHLMPCDTLARRRLSRSRAEAEGPGAGTARACPRGPEPPGSASSSSQESLRPPA
                     AAPALGSRPSRVEALRLRLRGTADDMLAVRLRRPLSPETRRRRSSWRRHTVVVQSPLT
                     DLNFNEWKELGGGGPQESVGVRPHSDNKDSGLSSLESTKARASSAASLPSGDLGALQG
                     LPQRRSAAARLHQCL"
     exon            1360..1515
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1516..1627
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1628..1685
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1829
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1830..2147
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2148..2209
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2210..2340
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2341..2462
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2463..2618
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..2697
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2698..2771
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2772..2861
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..2987
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2988..3029
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3030..3126
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3127..3158
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3159..5450
                     /gene="Arhgap23"
                     /gene_synonym="A330041B18Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcctaccgcc aggcagccga agagagccgg gtgggggaga ggggaagctt cagggagggc
       61 tggctaaggg gactaaggga cttaaatcag ctgtgcaggg gccctagtga gaggtagctg
      121 ggcagcagtc acaggctggc ggaatgctgt ctccgccact gtgatgctgg gagctccagg
      181 agccagcagg atggcaggag gaggaggcct actcccagga tgcctaccta aagggcaacg
      241 agccgtattc tggagaggcc cgcagcatcc cagaaccacc tccactctgc tacccacgga
      301 agacctatgc tccaccaacc agggcccctg cctgggctac tatggtgcct gagcccatct
      361 cagcactacc cccagatccc cggagtcctg ctgcctggag tgacccaggg tcccgtgtcc
      421 catctgccac ccgtgcccac ctggacaact cttccttggg gatgagccag ccccgcccaa
      481 gccctggtgc ctttccccac ctcccttcag agtcccggac accccgtgcc ttcccagagc
      541 ctggcagccg ggtgcttccc agcagactgg agtgccagca ggctctgtca cactggctgt
      601 ccaatcagat accccgcaga gcgggggaga gacggtgccc agccatgcca ccccgggccc
      661 gcagtgcctc ccaggaccgg ttggaggatg tgactaccca ccacccatgg ccctgctcca
      721 cctcccagga tgccttgagc cagctgggcc aggagggttg gcaccgagct cgctcagacg
      781 attacctgag ccgggctacc cgctctgctg aagcactggg tccaggagca ctggtgtccc
      841 ctcgtcttga acgctgtggt tgggcttccc agcgcccatc tgcccgcacc tctgcttgcc
      901 cttctcggga cttgacccag gcccctcccc catctggcct gcagggcctg gatgacatcg
      961 ggtacattgg atatcggagc tatagcccat cattccagcg ccggactggt ctcttgcacg
     1021 ccctctcctt ccgggactca ccctttgggg gacttcccac cttcagcttg gcccagtctc
     1081 ctgcatcatt cccaccagag gcctccgaac cacctagggt cgtccggcca gatcctagca
     1141 cccgagccct agagcctccc gcagaggatc atcgtgatga ggtggtcctg aggcagaagc
     1201 ctccaacggg tcgcaaggtc cagctgaccc cagcaaggca gatgaacctt ggatttggtg
     1261 atgagtcccc agaacccgag gccagagggg aacgcctggg gaggaaggta gcccctctgg
     1321 ccactacgga agactcgctg gcttctattc cctttattga cgagcccacc agccccagca
     1381 ttgaccttca ggccaagcat gtccctgcct ccgcagtggt ctccagtgcc atgaactcag
     1441 cccctgtcct gggaactagc ccatcctcgc caaccttcac ttttgccctc agccgccatt
     1501 actcccagga ctgcagcagc atcaaggcag gccgccgttc ctcctacctg ctggccatca
     1561 ccacggagcg ctccaagtcc tgtgacgatg gactgaacac cttccgggat gagggccgag
     1621 tgctccggcg ccttcccagc cgggtgccca gcctacgagt gctgcggagc ttcttcacgg
     1681 acgggtctct agatagctgg ggcacctctg aagatgctga tgccccctct aaacgacact
     1741 caacctctga cctctcagat gcaaccttca gtgatatcag gagagaaggc tggttgtatt
     1801 ataaacagat cctcaccaag aaggggaaga aagcgggcgg cggcctgcgc cagtggaagc
     1861 gcgtctatgc cgtcctgcgg gcgcgctcgc tctcgttgag caaggagcgg cgggagcccg
     1921 ggccggcggc tgcgggggct gcggcggccg gcgcaggtga ggacgaggcg gcgcccgtct
     1981 gcatcggctc ctgcctggtg gacatctcct acagcgagac caaaaggagg cacgtgttcc
     2041 ggctgaccac cgctgacttc tgtgaatatc tctttcaggc tgaggatcgg gatgacatgc
     2101 tgggctggat cagagcgatc cgggagaaca gcagggccga gggcgaggac cccggctgtg
     2161 ccaaccaagc tctgatcagc aagaagctta atgactatcg caaagtgagc catagctctg
     2221 ggcccaaagc cgattcctcc cctaaaggct ctcggggcct gggaggcctc aagtctgaat
     2281 tcctcaagca gactgcagtc cgcggcctca gaactcagga gcagccccca ggaagcaagg
     2341 aagacagtgt tgcagctccc aaaaccccct ggggcatcaa tattatcaag aagaacaaga
     2401 aggccgcccc gagggcattt ggaatccggt tggaggagtg ccagcctgcc accgagaacc
     2461 agcgtgtccc cctgatcgtt gctgcctgct gccgtattgt ggaggcccgg gggctggaat
     2521 caactggcat ttaccgggta cctggcaaca acgcagtggt gtctagcctg caggagcagc
     2581 tcaaccgtgg gccaagtgac atcaacctgc aggatgagcg ctggcaggac ctcaatgtca
     2641 tcagcagcct gctcaaggct ttcttccgca agctgccgga gcctcttttc actgatgaca
     2701 aatacaatga cttcatcgag gccaatcgga tagaagattc cagggagagg atgaagacgc
     2761 tgcggaagct gatccgggat ctcccaggac actactatga aacacttaaa ttccttgtgg
     2821 gccatctcaa gaccattgct gaccactcag agaagaacaa gatggaaccc cggaacctgg
     2881 ctctggtctt cgggccaaca ttggtaagga catctgaaga caacatgaca gacatggtga
     2941 cccacatgcc ggaccgctac aagatcgtgg agacgttgat ccagcattct gactggttct
     3001 tcagtgatga tgaggacaaa ggagagagaa cccctgttga tgacaaggag ccacagtcgg
     3061 tgcccaacat cgagtacctc ctgcccaaca ttggcaggac agtgcccccc agtgatccag
     3121 gctcagattc caccacctgt agctcagcca agtccaaggg ttcctgggtc cccaagaaag
     3181 agccttacgc ccgggagatg ctggcgatct ccttcatctc tgcggtcaac cgcaaacgga
     3241 agaagcggcg ggaggcgcgg ggcctgggca gcagcaccga cgatgactcc gagcaggagg
     3301 cgcacaaggc tgcggtgggg acgcaggagc cacccgaggg gcagctgccg ggccccgcag
     3361 ccgaggaggc ccctggtcgc ctcagccccc ctacggcacc cgacgaacgg cctgcggcgg
     3421 acacgcgctc catcgtctcg ggctactcca ccctgtccac catggaccgt agcgtgtgct
     3481 cgggcaccgg cgggcggcgc gcgggcgcgg gcgacgaggc ggacgacgaa cgcagcgagc
     3541 tgagccacgt ggagacggac acggaggggg gcgcaggccc cggggggcgc ctgtcgcgcc
     3601 ggccatcctt cagctcacac catctcatgc catgcgacac tctggcacgc cgtcgcctgt
     3661 ctcgcagccg cgcggaggcc gagggtccgg gcgcgggtac ggcccgggcg tgtccccgcg
     3721 gtccggagcc accgggctcg gcatcgtcca gcagccagga gtcgctgcgg cccccggcgg
     3781 ccgccccggc actcggctca cgaccttcgc gcgtggaagc cctgcggcta cgtctccgtg
     3841 gcaccgccga cgacatgctg gccgtgcggc tgcggcgccc actgtcgccc gagacgcggc
     3901 ggcgccggag tagctggcgc cgccacacag tggtggtgca gagcccgctg accgacctca
     3961 acttcaacga gtggaaggag ctgggtggag ggggccctca ggagtccgtg ggcgtgcgac
     4021 cgcacagcga caataaggac tctggcctca gcagcctgga gtccaccaag gcacgggcct
     4081 catccgccgc atcactgcca tctggggacc taggggccct gcagggtctg ccccagcgcc
     4141 gctcagctgc cgcccgcctc caccagtgtc tgtgataccc tcccctgttc cggggctgca
     4201 gaaattcccg tctcgtttgt gcccccctca gccaccccca gtgctgcaga aggttggggg
     4261 tggggtgtga agggcggcgc tggtgtggca ggctggagtt aggtgaggtg ggcagagaaa
     4321 tcaaagccag accgaagtgg gagtcctcag gagaggggag gggctattgg gagtcatgtc
     4381 ccttggatga agaaccgagt agcccttttc tgtgagtcta cttagggacc cttggtgacc
     4441 catgcagtgt gggtggaccg cccaagtttc atacagaagg aaaaatacag gctggattta
     4501 gggtctgtcc tctgcctccc cccccaatag ctcctagcca gggagagagg gaggatgaat
     4561 gtctgaggag cggttatgtg gggttgggtg tccatgggag agggggcatg tgtgtgtgtg
     4621 tgtgtgtgag agtgtgtatg tgtgtgtgtg tgtagtcaca gtgcaaaggt gtttgttacc
     4681 agtagctatt tctaccccaa ttcttttatt ttccccgcca ggaccctgcc tttggtgcac
     4741 acaggcacct tagccccaag tttgtcagag gctgggttga ggccacttcc acagaggcag
     4801 gactgaaccc cactactacc ggagtcgctc ctcacatcct ttgccgacct ctaagtcacc
     4861 cctctaagct ctctgacctg tggatctgtc tggatcccct tacagctggc atcttcctcc
     4921 tccatgttca ccctgcatcc ttcggcagct tagcatgcgg actcgccttc agtcgggagg
     4981 aactctgtcc ggcactgatg tatagagtct cagctgggct gttcttgcag ggtgggtggg
     5041 accagcttct cttcccacac attgtaaata gacctaaagc actagtcccc ctctgccctc
     5101 actcattcca ggggagcccc agtggggtga cctgctctgc tgcccaggtc tgtcagtctt
     5161 tcgggtttat gcaaagattt gctgtaaagt ctctcccccc tccctttcac tgtaaatatt
     5221 gtctctaatg tgtaacatat tataaagaat ttataaggat ttttaaagat gttttgctca
     5281 ttttaaaaag tgttgtaaca gtgttggata aagcccccca catctgcatg gctcctccca
     5341 ctgtgtcctt gacacacctc tctaggctat aactaagatt cctgcttctg aaagtcttgt
     5401 cttaaaagta cagtctatat cttggaaata aatggccttc ctcaggcatg
//
