LOCUS       NM_026565               1357 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus apolipoprotein O-like (Apool), transcript variant 1,
            mRNA.
ACCESSION   NM_026565 XM_989839
VERSION     NM_026565.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1357)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1357)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1357)
  AUTHORS   Cox,B.J., Vollmer,M., Tamplin,O., Lu,M., Biechele,S.,
            Gertsenstein,M., van Campenhout,C., Floss,T., Kuhn,R., Wurst,W.,
            Lickert,H. and Rossant,J.
  TITLE     Phenotypic annotation of the mouse X chromosome
  JOURNAL   Genome Res 20 (8), 1154-1164 (2010)
   PUBMED   20548051
REFERENCE   4  (bases 1 to 1357)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 1357)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   6  (bases 1 to 1357)
  AUTHORS   Nelson,P.S., Pritchard,C., Abbott,D. and Clegg,N.
  TITLE     The human (PEDB) and mouse (mPEDB) Prostate Expression Databases
  JOURNAL   Nucleic Acids Res 30 (1), 218-220 (2002)
   PUBMED   11752298
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV061158.1, AK012398.1 and AI132704.1.
            
            On Sep 1, 2015 this sequence version replaced NM_026565.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU518908.1, AK079141.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-262               DV061158.1         59-320
            263-1274            AK012398.1         253-1264
            1275-1357           AI132704.1         1-83                c
FEATURES             Location/Qualifiers
     source          1..1357
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 48.76 cM"
     gene            1..1357
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /note="apolipoprotein O-like"
                     /db_xref="GeneID:68117"
                     /db_xref="MGI:MGI:1915367"
     exon            1..85
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..868
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; MICOS complex subunit Mic27"
                     /codon_start=1
                     /product="MICOS complex subunit Mic27 isoform 1 precursor"
                     /protein_id="NP_080841.1"
                     /db_xref="CCDS:CCDS30359.1"
                     /db_xref="GeneID:68117"
                     /db_xref="MGI:MGI:1915367"
                     /translation="MAAFRMGKLTTIPAGLIYASINVRLAKEEEPKKQLVRPDQLPIY
                     TAPPLHSKYVEEQPGNLQRGFASIRTTTVYYIGWCKSIYLFMKNGVMDTVQFGKDAYV
                     YLKNPPQDFLPKMGVITASGLAGLLSARKGSRFKKIAYPLGLATLGATVCYPAQSVII
                     AKITGKKAYATSQQIFQAIKSLWTQKSENESLPEPKEESKEGRSDEIHASLPDLKHSV
                     SLPKELASATVIKSESTSGTTQFIPDPKLMDHGQSHPDDKDMYSTRS"
     exon            86..190
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /inference="alignment:Splign:2.1.0"
     exon            191..310
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /inference="alignment:Splign:2.1.0"
     exon            311..365
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /inference="alignment:Splign:2.1.0"
     exon            366..464
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /inference="alignment:Splign:2.1.0"
     exon            465..556
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /inference="alignment:Splign:2.1.0"
     exon            557..670
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /inference="alignment:Splign:2.1.0"
     exon            671..779
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /inference="alignment:Splign:2.1.0"
     exon            780..1341
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /inference="alignment:Splign:2.1.0"
     regulatory      996..1001
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /note="hexamer: AATAAA"
     polyA_site      1016
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /note="major polyA site"
     regulatory      1317..1322
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
                     /note="hexamer: AATAAA"
     polyA_site      1341
                     /gene="Apool"
                     /gene_synonym="6720473G16Rik; 9430083G14Rik;
                     E130106L15Rik; Micos27"
ORIGIN      
        1 caaggcaaag tgaactgctt tgtccctctg cgctctccgt ctgaaaactt gagccgagag
       61 ggtcataggt atggcggcct ttaggatggg aaagttgaca accatacctg caggtctgat
      121 atatgcatct ataaatgtgc gtcttgccaa agaagaggaa cccaaaaagc agctagtgag
      181 accggatcag ctccccatat atactgcacc acccctccat tctaaatatg ttgaagaaca
      241 gcctggtaat ttacaaaggg gctttgcatc catccgtact acaaccgtgt attatattgg
      301 ctggtgcaag agcatttatc tctttatgaa gaatggggtt atggatacag tacagtttgg
      361 aaaagatgca tatgtctatc tgaagaatcc tccgcaagat tttctcccca aaatgggagt
      421 gattacagct tcgggactgg caggtttgct ttcagcaaga aaaggttcca ggtttaagaa
      481 gattgcttat ccactaggac tggccacatt aggagcgact gtttgctacc cagctcagtc
      541 agtaataatt gcaaagataa ctgggaaaaa ggcatatgct acaagccagc aaatttttca
      601 agccattaag tcattgtgga cacaaaaaag tgaaaacgaa tcactccctg aaccaaagga
      661 agaaagcaag gaaggaaggt ctgatgaaat ccatgccagc ttgcctgacc tgaaacattc
      721 agtgtctttg ccaaaagaac ttgcctctgc aacagtgatt aaatcagaat ctacctcagg
      781 tactacacag ttcattcctg accccaagct catggatcat gggcagtctc atccagatga
      841 taaagatatg tacagcacta gaagctgaac tagtttgcag agggagcctg catagagaac
      901 tgcaagatgt accaagttgc aaacaatggt gaaaaatcac ataatgaacg ggtaactgac
      961 aaaatgtgac ttgaaatttt tccacgacat tttcaaataa acagtttggc caatgataca
     1021 agtggtaaaa tcataaatta atgaatgcaa cataaatatt attaggtgat tgatgtggga
     1081 actgaggtag aaatgctaga agtacatttc atgacttgta atagaattta ttagaaagca
     1141 aaatgaagtg aagatatgtc cgtaagactg aattctataa acatgcatat gtatgtatgt
     1201 acgtatgtat gtatgtatgt atgtgtctgc ttcagttttc ccaattattg ccagttaact
     1261 tacaatgggg gtagacgaat gagtttttca cttgactttt ttttttttag agctagaata
     1321 aattatccat attttattgc aaaaaaaaaa aaaaaaa
//
