LOCUS       NM_001109914            3284 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus apolipoprotein L domain containing 1 (Apold1), mRNA.
ACCESSION   NM_001109914 NM_001101508 XM_355823
VERSION     NM_001109914.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3284)
  AUTHORS   Fan Z, Ardicoglu R, Batavia AA, Rust R, von Ziegler L, Waag R,
            Zhang J, Desgeorges T, Sturman O, Dang H, Weber R, Roszkowski M,
            Moor AE, Schwab ME, Germain PL, Bohacek J and De Bock K.
  TITLE     The vascular gene Apold1 is dispensable for normal development but
            controls angiogenesis under pathological conditions
  JOURNAL   Angiogenesis 26 (3), 385-407 (2023)
   PUBMED   36933174
  REMARK    GeneRIF: The vascular gene Apold1 is dispensable for normal
            development but controls angiogenesis under pathological
            conditions.
REFERENCE   2  (bases 1 to 3284)
  AUTHORS   Diaz-Canestro C, Bonetti NR, Wust P, Nageswaran V, Liberale L, Beer
            JH, Montecucco F, Luscher TF, Bohacek J and Camici GG.
  TITLE     Apold1 deficiency associates with increased arterial thrombosis in
            vivo
  JOURNAL   Eur J Clin Invest 50 (2), e13191 (2020)
   PUBMED   31797367
  REMARK    GeneRIF: Apold1 deficiency associates with increased arterial
            thrombosis in vivo.
REFERENCE   3  (bases 1 to 3284)
  AUTHORS   Mirza MA, Capozzi LA, Xu Y, McCullough LD and Liu F.
  TITLE     Knockout of vascular early response gene worsens chronic stroke
            outcomes in neonatal mice
  JOURNAL   Brain Res Bull 98, 111-121 (2013)
   PUBMED   23973431
  REMARK    GeneRIF: The resiults of this study suggests that Verge plays an
            important role in the induction of neurogenesis and angiogenesis
            after ischemia, contributes to improved tissue repair, and enhances
            chronic functional recovery.
REFERENCE   4  (bases 1 to 3284)
  AUTHORS   Liu F, Turtzo LC, Li J, Regard J, Worley P, Zeevi N and McCullough
            LD.
  TITLE     Loss of vascular early response gene reduces edema formation after
            experimental stroke
  JOURNAL   Exp Transl Stroke Med 4 (1), 12 (2012)
   PUBMED   22681709
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC122193.5.
            
            On or before Oct 12, 2007 this sequence version replaced
            NM_001101508.1, XM_355823.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.172290.1,
                                           SRR7345562.905150.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                AC122193.5         191029-191057
            30-3284             AC122193.5         192610-195864
FEATURES             Location/Qualifiers
     source          1..3284
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 65.77 cM"
     gene            1..3284
                     /gene="Apold1"
                     /gene_synonym="Gm1075"
                     /note="apolipoprotein L domain containing 1"
                     /db_xref="GeneID:381823"
                     /db_xref="MGI:MGI:2685921"
     exon            1..29
                     /gene="Apold1"
                     /gene_synonym="Gm1075"
                     /inference="alignment:Splign:2.1.0"
     exon            30..3284
                     /gene="Apold1"
                     /gene_synonym="Gm1075"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..773
                     /gene="Apold1"
                     /gene_synonym="Gm1075"
                     /codon_start=1
                     /product="apolipoprotein L domain-containing protein 1"
                     /protein_id="NP_001103384.1"
                     /db_xref="CCDS:CCDS51938.1"
                     /db_xref="GeneID:381823"
                     /db_xref="MGI:MGI:2685921"
                     /translation="MEKRAAWEPQGADALRRFQGLLLDRRGRLHSQVLRLREVARRLE
                     RLRRRSLAANVAGSSLSAAGALAAIVGLSLSPVTLGASLVASAVGLGVATAGGAVTIT
                     SDLSLIFCNSREVRRVQEIAATCQDQMRELLSCLEFFCQWQGRRDRQLLQSGRDASMA
                     LYNSVYFIVFFGSRGFLIPRRAEGATKVSQAVLKAKIQKLSESLESCTGALDELSEQL
                     ESRVQLCTKAGRGHNLRISTDLDAALFF"
ORIGIN      
        1 acttttcttc ctggaggcca gagtgaaggg gcatggagaa gcgggcggcc tgggagccgc
       61 agggcgccga tgcgctgcgg cgcttccaag gattgctgct ggaccgccgt ggccggctgc
      121 acagccaagt gctgcgcctg cgcgaagtgg cccggaggct ggagcggcta cgcaggcgct
      181 ccctggcggc caacgtggcg ggcagctctc tgagcgccgc tggtgccctg gcagccatcg
      241 tggggttgtc actcagcccg gtcaccctgg gagcctcgct cgtggcgtcg gccgtgggct
      301 taggggtggc caccgccgga ggggcagtca ccatcacgtc cgacctctct ctgatcttct
      361 gcaattcccg ggaggtgcgg agggtgcagg agatcgccgc cacctgccag gaccagatgc
      421 gcgagcttct gagctgcctg gagttcttct gtcagtggca gggacgcagg gaccgccagc
      481 tgctgcagag cgggagggac gcctccatgg ccctttacaa ctctgtctac ttcatcgtct
      541 tcttcggctc acgtggcttc ctcatcccca gacgtgccga gggggccacc aaagtgagcc
      601 aggccgtcct gaaggccaag attcagaaac tgtcagagag cctggagtcg tgcactggcg
      661 ccctggatga acttagtgag cagctggagt cccgggtcca gctctgcacc aaggccggcc
      721 gtggccacaa cctcaggatc tccactgatc tggacgcagc gttgtttttc taagagcatc
      781 ctctacctat atggaatgtt ctagagtcgt agcatccaca gggaagtgct acatgggtgg
      841 agtgcaaagg atgataggaa ctcttcttgc agggcttccg tcagtcctta gctccttgtg
      901 tgtgtgaagg acttttcgct tgtgtaatcc caactgagta tgtgatcctt tttgtctttg
      961 tagggattgt agacccaacc tgggccgcgg agctgacttg ctctgctctt cccaccccag
     1021 tttatccact catagaccaa atctgactat tgcatacttt cccagcatgg cttcaaattc
     1081 acacctctag gtaccctgag agggaaagcc acccgaagag tcactttaat cccaacatac
     1141 tcacccgcct tcacttctgt aaagaagctg ggggaggggt gagatgcagt ccctgacaat
     1201 tttaaataac tgaccacaaa gaggagagca acggcctttg agttaaacag tcttggactg
     1261 atcacaggct ctgtccccca ccggtcgtgt gacttagcca ccttctcttg ctgagacttg
     1321 gcttgttcag tgacacagat ggtggtaaga acacaccctg ttgtgaagcc ctgagataag
     1381 aaaggacctt cagagtcact ctcagaaagt ccaggaaaga ctggcccagc agcccaagaa
     1441 agactatgct gtgtgcttgt aaagccagtt actctgtccc ctgtaaacta gaagacagag
     1501 cagcacagac cctttagagg gcagtgttgc ccattccatg tagagactgg tacagaggta
     1561 atgtgaagtt accagcaaaa acaaacaaaa tcaaaaacaa aaaataaaaa caaaacaaac
     1621 aaacaaaaaa aaccccaaac ctctttatcc tctgaaaact ccagacacca tatctttatt
     1681 tatttaaaat tagttattta atttctgtgt attatttaca tttgatttta tttaactata
     1741 gcatttagaa aataataaga atattaaggg tctgaatagg aagggagtct gttaaggctc
     1801 tttccaggag gtcaggtttg gatttctaga gtctttttcc ctcagagagg actctctagt
     1861 gtttggcacg atccctgtaa gtaagatggg ggagtcctga ggagagagag agagactaaa
     1921 ctgattttta aactggtaaa tggagtcttg aattgtggaa tatatgaatg attaagcctg
     1981 tgtgtcctga aggtactttg ccagaaagca cttgacttga aaaagaaaac ctatttaatt
     2041 caggagtgga ggaatagaga ctcatgaagg aaacatttag accttggaaa cctgtcctat
     2101 gaaattctgt ttttataaaa ttgtgttatg atagagatct gtcacatttt gactttgggg
     2161 ctgtaagaaa cctgctatct atgcttaaga aagtacttct aatttattca atatcttcct
     2221 aaattatcct ttagaaagag ttgcaaagtc tttgggacca tacccaggaa accttggctg
     2281 tatatttaaa ttatttaatg ctatacattt gcgcagcccc tatgattccc agtgatggcc
     2341 acgtgtctga ggaaatgttt tggcatgagg gggaggggtg ctctttctat atttattttt
     2401 gtttcctata aactgtagtt ggcgtatatc ctgatttaat ttgacattga tgtggctttt
     2461 tttttttttt ttgacactgt gtctttctct aggcagccct ggatgtccca gaactcactc
     2521 tgtagatcag gctgacctca aactcacaga gtttgcttct gcctcctgag tgctgggatt
     2581 aaaggaatac acagcatgcc cagcttgggt tttttttttg tttttgtttt tgtttttgtt
     2641 ttgttttgtt tttaactgct gtcactttta gactgcctgt gtgggcactg gagtatacct
     2701 caggctctcc ttccatcatc cggctgaagc cattccctga cgccgtcatg cattggtgct
     2761 ttgtctcggg ttatactcct ccattaccga cctgttccat ataacccaaa atgggaatgt
     2821 tttgagtata tagcaaagta ctaagcttct gaaggtttta tcagtggtct gctgtgtgcg
     2881 catctgagag tgtctacttt ccatccacag atggcagaag ggtctagagg ttgagttcca
     2941 gggcacccga gctacacaat gagacctcat ctcaaaaata caatgaaaca acaaaaactg
     3001 aaagcacatt tgaataattc gctgtttgtc tgtattatga gggattagct tggtcattct
     3061 ctttcttatg tgtaggcatg ttgtgaaaat tggaggattt gccaggggtt agcaaagttc
     3121 agtacaattg atcctagaga caaattgttt atttctttca tgggacagtg gagtgggttt
     3181 tccctttcga ccgtcattct ataagcaagc aggtcgaaag ggtttgtggc gcaaatgaaa
     3241 agagagaaat aaatgttagg gtttggaaaa tacatgtttg ttct
//
