LOCUS       NM_001162883            1475 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus apolipoprotein L 9a (Apol9a), transcript variant 2,
            mRNA.
ACCESSION   NM_001162883
VERSION     NM_001162883.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1475)
  AUTHORS   de Reuver R, Verdonck S, Dierick E, Nemegeer J, Hessmann E, Ahmad
            S, Jans M, Blancke G, Van Nieuwerburgh F, Botzki A, Vereecke L, van
            Loo G, Declercq W, Hur S, Vandenabeele P and Maelfait J.
  TITLE     ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1
            activation
  JOURNAL   Nature 607 (7920), 784-789 (2022)
   PUBMED   35859175
REFERENCE   2  (bases 1 to 1475)
  AUTHORS   de Reuver R, Dierick E, Wiernicki B, Staes K, Seys L, De Meester E,
            Muyldermans T, Botzki A, Lambrecht BN, Van Nieuwerburgh F,
            Vandenabeele P and Maelfait J.
  TITLE     ADAR1 interaction with Z-RNA promotes editing of endogenous
            double-stranded RNA and prevents MDA5-dependent immune activation
  JOURNAL   Cell Rep 36 (6), 109500 (2021)
   PUBMED   34380029
REFERENCE   3  (bases 1 to 1475)
  AUTHORS   Arvind TA and Rangarajan PN.
  TITLE     Mouse Apolipoprotein L9 is a phosphatidylethanolamine-binding
            protein
  JOURNAL   Biochem Biophys Res Commun 479 (4), 636-642 (2016)
   PUBMED   27697524
  REMARK    GeneRIF: ApoL9 is a phosphatidylethanolamine -binding protein that
            may have important roles in several cellular processes that involve
            this phospholipid.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ058381.1 and AL772386.4.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1 and 2 encoded the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057684.2, CJ058381.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-413               CJ058381.1         2-414
            414-1475            AL772386.4         19698-20759
FEATURES             Location/Qualifiers
     source          1..1475
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 36.4 cM"
     gene            1..1475
                     /gene="Apol9a"
                     /note="apolipoprotein L 9a"
                     /db_xref="GeneID:223672"
                     /db_xref="MGI:MGI:3606001"
     exon            1..55
                     /gene="Apol9a"
                     /inference="alignment:Splign:2.1.0"
     exon            56..181
                     /gene="Apol9a"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..1031
                     /gene="Apol9a"
                     /codon_start=1
                     /product="apolipoprotein L 9a"
                     /protein_id="NP_001156355.1"
                     /db_xref="CCDS:CCDS49660.1"
                     /db_xref="GeneID:223672"
                     /db_xref="MGI:MGI:3606001"
                     /translation="MASSGYLYSLVAEDGVWQAFVSKAKLSRERAVALHKALRELTAL
                     LAIADRGRLQKGLKGREKFLKVFPRLKAELVEHISQLHALADHAEKLHRGCTISNVVA
                     DSFSAASDILSLLGLFLAPVTAEGSLVLSATGLGLGVAATVTDVATSIVEETSRVLDE
                     VEAAPTGTHVLGEAGTSVDRIASKVPQATRDITRDLEALEQHMNALRLVRANPRLEED
                     ARILATTGSISAQRAMQVRASLKGTPLAMSNEARIQRATAAGAALWSDVDSLVKESKH
                     LYEGSASESAEALRKLARELEEKLEGLMEFYKTI"
     exon            182..1475
                     /gene="Apol9a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaggtgcag ctgccaactg catctgcgaa gccaaggcca tctgggtcct gttagagagc
       61 agacacacca tccagggagc cactgggtat ctcagaacat ggcaagcagt ggatacctgt
      121 atagcctggt ggctgaagat ggagtctggc aggcgtttgt atccaaggcc aagttgtcca
      181 gggagagagc agtggccctc cacaaagctc tgagggaact gacagcgctc ttggccatag
      241 cagacagagg cagacttcaa aaaggtctga aaggcaggga gaagtttttg aaagtctttc
      301 ctcgcttgaa agcagagctg gtggagcata tcagtcagct ccatgccctg gctgaccacg
      361 ctgagaaact acacaggggc tgcaccatct ccaacgtggt ggctgactcc ttcagtgctg
      421 cctctgacat cctgagcctc cttggtctct ttctggcacc tgtgacagca gagggaagtc
      481 tggtgctctc agcaactggc ttggggctgg gggtagcagc tactgtgact gatgttgcta
      541 cctcaatcgt ggaggaaaca agcagggttt tggatgaagt tgaagctgct ccgactggca
      601 ctcatgtgct gggggaggct ggcacaagtg tggataggat tgccagcaag gtccctcagg
      661 ctaccagaga catcactaga gacctggaag cccttgagca gcacatgaat gccctcaggc
      721 tggttagagc caaccctcgt ttagaagaag atgccaggat cctggccacc acaggaagca
      781 tctctgccca acgggctatg caggtgcggg ccagtctgaa aggaacccct ctggcaatga
      841 gcaatgaagc ccggatccaa cgtgccaccg ccgcaggtgc cgccctctgg agtgatgtgg
      901 acagccttgt caaagagtca aagcatctgt acgaagggtc tgcgtcagag tcggctgaag
      961 cactgaggaa gctggctcga gagctggagg agaagctaga ggggctcatg gaattctaca
     1021 agacgatctg atcaggcccc agtcagtcac cccatcccca agacaggcag aggtcagggg
     1081 agaggacctg gacagaggag agcaagactg cagtcaggtc cgagggaccg agtgtgcagg
     1141 cctgctgctg aacacagcac aatcaggtga gaccccctgg tgcctgagac gagagactaa
     1201 aggatgtgct gctgtgagag ggactggaaa gattgaactc tggactaaac acggaagaag
     1261 ccagttaaga gaaggactag aaagccctcc ccagctgagc tactgcaaac aagaccccac
     1321 aaaaggcaaa ccagagagaa aggtgtgtgc tctgtaaaca catcatgagc cccatccctg
     1381 tgctttagag cctgtgcttc tccccagctc cccagcccac gcccatcctc aggcatgtca
     1441 ttgtccccta aataaaccgt ttctgttgtt cctca
//
