LOCUS       NM_009686               6671 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus amyloid beta precursor protein binding family B member
            2 (Apbb2), transcript variant 1, mRNA.
ACCESSION   NM_009686 NM_001012327
VERSION     NM_009686.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6671)
  AUTHORS   Lin YH, Shih YH, Yap YV, Chen YW, Kuo HL, Liu TY, Hsu LJ, Kuo YM
            and Chang NS.
  TITLE     Zfra Inhibits the TRAPPC6ADelta-Initiated Pathway of
            Neurodegeneration
  JOURNAL   Int J Mol Sci 23 (23), 14510 (2022)
   PUBMED   36498839
  REMARK    GeneRIF: Zfra Inhibits the TRAPPC6ADelta-Initiated Pathway of
            Neurodegeneration.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6671)
  AUTHORS   Strecker P, Ludewig S, Rust M, Mundinger TA, Gorlich A, Krachan EG,
            Mehrfeld C, Herz J, Korte M, Guenette SY and Kins S.
  TITLE     FE65 and FE65L1 share common synaptic functions and genetically
            interact with the APP family in neuromuscular junction formation
  JOURNAL   Sci Rep 6, 25652 (2016)
   PUBMED   27734846
  REMARK    GeneRIF: These data demonstrate a role for FE65 proteins at central
            and peripheral synapses.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6671)
  AUTHORS   Suh J, Moncaster JA, Wang L, Hafeez I, Herz J, Tanzi RE, Goldstein
            LE and Guenette SY.
  TITLE     FE65 and FE65L1 amyloid precursor protein-binding protein compound
            null mice display adult-onset cataract and muscle weakness
  JOURNAL   FASEB J 29 (6), 2628-2639 (2015)
   PUBMED   25757569
  REMARK    GeneRIF: Findings show that amyloid precursor protein-binding
            proteins FE65 and FE65L1 are essential for the maintenance of lens
            transparency.
REFERENCE   4  (bases 1 to 6671)
  AUTHORS   Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H,
            Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T,
            Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P,
            Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ,
            Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD,
            Flicek P, Skarnes WC, Mallon AM and Parkinson H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 6671)
  AUTHORS   Suh J, Lyckman A, Wang L, Eckman EA and Guenette SY.
  TITLE     FE65 proteins regulate NMDA receptor activation-induced amyloid
            precursor protein processing
  JOURNAL   J Neurochem 119 (2), 377-388 (2011)
   PUBMED   21824144
  REMARK    GeneRIF: FE65 proteins contribute to physiological APP processing
            and accumulation of amyloid precursor protein metabolic products
            resulting from NMDA receptor activation
REFERENCE   6  (bases 1 to 6671)
  AUTHORS   Kimberly WT, Zheng JB, Guenette SY and Selkoe DJ.
  TITLE     The intracellular domain of the beta-amyloid precursor protein is
            stabilized by Fe65 and translocates to the nucleus in a notch-like
            manner
  JOURNAL   J Biol Chem 276 (43), 40288-40292 (2001)
   PUBMED   11544248
REFERENCE   7  (bases 1 to 6671)
  AUTHORS   Cao H, Pratt N, Mattison J, Zhao Y and Chang NS.
  TITLE     Characterization of an apoptosis inhibitory domain at the C-termini
            of FE65-like protein
  JOURNAL   Biochem Biophys Res Commun 276 (3), 843-850 (2000)
   PUBMED   11027557
REFERENCE   8  (bases 1 to 6671)
  AUTHORS   Pappolla MA, Chyan YJ, Omar RA, Hsiao K, Perry G, Smith MA and
            Bozner P.
  TITLE     Evidence of oxidative stress and in vivo neurotoxicity of
            beta-amyloid in a transgenic mouse model of Alzheimer's disease: a
            chronic oxidative paradigm for testing antioxidant therapies in
            vivo
  JOURNAL   Am J Pathol 152 (4), 871-877 (1998)
   PUBMED   9546346
REFERENCE   9  (bases 1 to 6671)
  AUTHORS   Cao H, Mattison J, Zhao Y, Joki N, Grasso M and Chang NS.
  TITLE     Regulation of tumor necrosis factor-and Fas-mediated apoptotic cell
            death by a novel cDNA TR2L
  JOURNAL   Biochem Biophys Res Commun 227 (1), 266-272 (1996)
   PUBMED   8858135
REFERENCE   10 (bases 1 to 6671)
  AUTHORS   Van der Bliek,A.M., Van der Velde-Koerts,T., Ling,V. and Borst,P.
  TITLE     Overexpression and amplification of five genes in a
            multidrug-resistant Chinese hamster ovary cell line
  JOURNAL   Mol Cell Biol 6 (5), 1671-1678 (1986)
   PUBMED   2431283
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY333882.1, AK004792.1 and AC131752.3.
            
            [WARNING] On Jan 25, 2024 this sequence was replaced by
            NM_009686.3.
            
            On Jul 3, 2013 this sequence version replaced NM_009686.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004792.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               BY333882.1         1-146
            147-3508            AK004792.1         1-3362
            3509-6671           AC131752.3         120230-123392
FEATURES             Location/Qualifiers
     source          1..6671
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 34.43 cM"
     gene            1..6671
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /note="amyloid beta precursor protein binding family B
                     member 2"
                     /db_xref="GeneID:11787"
                     /db_xref="MGI:MGI:108405"
     exon            1..250
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            251..406
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            407..521
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            522..590
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     CDS             572..2854
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger-like protein; protein Fe65-like 1; amyloid beta
                     (A4) precursor protein-binding, family B, member 2"
                     /codon_start=1
                     /product="amyloid beta precursor protein binding family B
                     member 2 isoform 1"
                     /protein_id="NP_033816.1"
                     /db_xref="CCDS:CCDS51510.1"
                     /db_xref="GeneID:11787"
                     /db_xref="MGI:MGI:108405"
                     /translation="MSEVLPADSGVGTLAVFMASSGSTDIANRNSPATPPNTLNLRSS
                     HNELLNAEIKHSDAKNSTPPKCRKKYALTNIQAAMGLSDPAVQPLLGNGSANIKLVKN
                     GENQLRKAAEQGQQDPNKNLSPAAVINLTSEKLEVKDPHPQESSGCEILPSQPRRTKS
                     FLNYYADLETSARELGQNLGPCQGVGEEKAQPGPGQAPVVIGNGDLLPQKPNKPQSSP
                     EDGQVATVSSSPETKKDHPKTGAKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPD
                     ETDIWSDHSFQTDPDLPPGWKRVNDIAGTYYWHIPTGTTQWERPVSIPADLHGSRKGS
                     LSSVTPSPTPENEKQPWSDFAVLNGGKINSDIWKDLHAATVNPDPSLKEFEGATLRYA
                     SLKLRNAPHGDDDDSCSINSDPEAKCFAVRSLGWVEMAEEDLAPGKSSVAVNNCIRQL
                     SYCKNDIRDTVGIWGEGKDMYLSLENDMLSLVDPMDRSVLHSQPIVNIRVWGVGRDNG
                     RERDFAYVARDKDTRILKCHVFRCDTPAKAIATSLHEICSKIMAERKNAKALACSSLQ
                     ERTNMSLDVPLQVDFPTPKTELVQKFRVQYLGMLPVDRPVGMDTLNSAIENLMTSSSK
                     EDWPSVNMNVADATVTVISEKNEEEVLVECRVRFLSFMGVGKDVHTFAFIMDTGNQRF
                     ECHVFWCEPNAANVSEAVQAACMLRYQKCLVARPPSQKVRPPPPPADSVTRRVTTNVK
                     RGVLSLIDTLKQKRPVTETP"
     exon            591..1406
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1612
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            1613..1675
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1761
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            1762..1822
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..1969
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2097
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2103
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2218
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2306
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            2307..2390
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            2391..2506
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            2507..2686
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
     exon            2687..6671
                     /gene="Apbb2"
                     /gene_synonym="2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccggctcc gccaggcccc tccaagcctt tcctcgcgca gccgccgcca aagcctggag
       61 aagtggaatc tcgctgccgc tgctccctgc gcgggcctcg cggagccgca ctgggcatgc
      121 tcagtcgccg gagccagtgc tgctctaagt aggaagctcg cgtgctgcag cccgcagctg
      181 atccgggtgc tcagcggact gcgagacctg ggagccgggt ccggagccga tcgaacgccg
      241 cgcagcgctg gttgagcctc tgtagggagc tgctgtgctc tccagccaag catgctgtgg
      301 tcagatctgc ccagccctgg aatagaatcc tttgccggat ggaaaatcca taaaagaaag
      361 ctcttgtgaa gagctgattc ccacctgctg acttaagtgc gcccagctag ccctctctct
      421 gtttctggag tccttgggag ttcctgagtc ccccactcac acgctgactg tcgctatggg
      481 cagaaggtac ccagaggctc gagggtgtcc aagcagctca tatctcaaat tataacctgt
      541 ttcctgcacc attgctgacg tccaacgatc catgtcagaa gtacttccag ctgactcagg
      601 tgttggcacc ttggcagtgt ttatggccag cagcggatcc acagacattg caaaccggaa
      661 cagcccagcc acaccaccaa ataccctcaa tctccgttcc tcccacaatg aactattaaa
      721 tgcagagatc aaacactcag atgccaagaa cagcacgccc cccaaatgca ggaaaaaata
      781 tgcactgact aatattcagg cggccatggg cctctcggat ccagctgtac agcccctgct
      841 gggaaacggc tctgccaaca tcaagctggt taaaaatggg gagaaccagc tccgcaaggc
      901 tgcagaacag gggcagcagg accccaacaa gaacctcagc cctgcagccg tcatcaacct
      961 aacctccgag aagctggagg ttaaagatcc ccacccacag gagtcttcag gctgtgagat
     1021 tttgccctcc cagcccagga gaactaagag cttcctcaat tactatgcag acctggaaac
     1081 ctcggctaga gagctagggc agaacctggg cccctgccaa ggggttggag aggagaaagc
     1141 ccagcctggc ccaggccagg ccccagtagt cattgggaat ggtgacttgc tgccacagaa
     1201 accaaacaaa ccccaatcca gcccagagga tggccaagta gccacagtat cgtccagccc
     1261 agagaccaag aaagaccacc ctaaaacagg agccaaaacc gactgtgccc tccatcggat
     1321 ccagaacctg gcaccaagtg acgaggaatc cagctggacg acgctgtccc aagacagtgc
     1381 ctcccccagc tccccagatg aaacagatat ctggagtgat cactcatttc agacagatcc
     1441 cgatttgccg ccgggctgga agagagtcaa tgacattgcc gggacctatt actggcacat
     1501 cccaacaggg acgactcaat gggaacggcc tgtctccatc ccagcagatc tccacggctc
     1561 taggaaaggg tcacttagtt ctgtaacgcc atcgcccacc ccagagaatg agaaacagcc
     1621 atggagtgat tttgctgttc tgaatggggg aaagattaat agtgacattt ggaaggattt
     1681 gcacgcagcc acagttaacc cagaccccag tttaaaagag tttgaaggag caacgctacg
     1741 ctatgcatcc ttgaaactca gaaacgcccc tcatggtgat gacgatgatt cttgtagtat
     1801 caacagtgac ccagaagcca agtgttttgc tgtgcgttct ctgggctggg tagagatggc
     1861 cgaggaggac cttgcccccg ggaagagcag tgtcgctgtc aacaactgca tccgacagct
     1921 ttcctactgc aaaaacgaca tccgggacac agtcggcatc tggggagagg gcaaagacat
     1981 gtacctgagc ctggaaaacg acatgctcag cctggtggac cccatggacc gctccgtgtt
     2041 acactcccag cccatcgtga acatccgagt gtggggcgtg ggccgagaca acggccgaga
     2101 gagggacttt gcttacgtgg cgagagacaa ggacacaagg attctgaaat gccatgtgtt
     2161 tcgatgtgac acaccagcaa aagccattgc cacaagtctc cacgaaatct gctccaagat
     2221 tatggctgaa cggaagaacg ccaaagcact ggcctgcagc tccttacagg agaggaccaa
     2281 tatgagtctc gatgtccctt tgcaagtaga ttttccaaca ccaaagacgg agctggtgca
     2341 gaagttccgc gtgcagtacc tgggcatgtt acctgtagac agacctgtcg gcatggacac
     2401 cctgaacagt gccatagaaa atctcatgac gtcatccagc aaggaggact ggccttcggt
     2461 gaacatgaac gtggccgacg ccactgtgac tgtcatcagt gaaaagaatg aagaggaggt
     2521 cttggtggag tgtcgagtgc ggttcctgtc cttcatgggt gtcgggaagg atgtccacac
     2581 attcgccttc atcatggaca ctgggaacca gcgctttgag tgccatgtgt tctggtgtga
     2641 gcctaacgca gccaatgtgt cagaagctgt ccaggctgcc tgcatgttgc ggtatcagaa
     2701 gtgcttggtt gccaggccac cttcgcagaa agtccggccc ccgcccccgc cagcagattc
     2761 agtgacccga agagtcacga ccaatgtgaa acgaggggtc ttatccctca ttgacacttt
     2821 gaaacagaag cggccggtca cagagactcc ctagcagccc aggtctggag gagtctgaca
     2881 ccattacctg aggatcaagt agctacacta aagaagccga tacctggcct tccactcagt
     2941 tgccgatgct ttgtctccag agattttatc tttaaccaga cagtgttaga caagcatgtg
     3001 acctcgtctt gccgccacca tgtgatataa agaggagcat gattttttct ttcctgtaag
     3061 ttacatcatg agcagcagaa ggtcgtcttc ttgtaaatat tgtgaacagg acttccgagc
     3121 acacacacag aagaatgcgg ccacaccctt cctagccaac taacactgca tccttggacg
     3181 aacggtgccc aagttcattt tgctgtcctc ttgactggat ctgtcacaag ccaacttggg
     3241 gtccctcagc actttgccct gatttcggat cctgagtaac agataccact gaattgctgt
     3301 aacaatgggg tgacaccttt gggttttagt ttttcataac actgagcctg ttggttgaca
     3361 aaacttggct gttggcgtcg gtacagacac cagccaccga gctctctgac acatggacac
     3421 tggttcacat ctacagctat ttgaggtgcc gggcaaagga gaactttaaa attgatagaa
     3481 aactaaattt gaggaattaa aatcaagcaa aaaaaaaaaa aaaaggcctt tcttttcaga
     3541 tggttttcag actggttatt ttaaaaaaga gatttacaga gtcatgacgc atttgggatg
     3601 gaacgtattt caaacttctg ccttacactg tacaatgcag ctagagaatt aaagtgtact
     3661 atggccattc tctacccaca cctggaaaat gaaatattcc taccgtttcc atccttagtt
     3721 tgataccgag ctaatatgca atttagaatc gaggaaatgt catttatatc tgtcacacgc
     3781 cattattttc gatctccacc gtaattcttg ttagctctca ccccggaggt aaatgcactc
     3841 ctgggattcc gccactgccc cagcctctct ctgctctttg tccaggaagc tgtctgtcca
     3901 tcatctgttg tccatggcaa caaatcttaa gttgtaattt ccctgaattt atgtgtttaa
     3961 tgttagaagt ttgttaagac ttgactagat gtgtttttaa acatctattt ttttccattt
     4021 tattttcaag atttaatttt tttcctatca gcaaaaataa tggatttcct tatagtgact
     4081 cccacatatc atgttcctgc ctctctttta tgtagctaag gaacctaaac cataaacata
     4141 tacaaatgta gactcttgtt tacattgtta ttttaaaagg cccatcttat tagtatttac
     4201 tgttaatgtc aaaactaata tcgttataaa atagtggggc tttttccctt gctctgtacc
     4261 tgtcagaacg gtctgcagtt ttatcacatt ggagccttac atggtaggaa aggcgctgac
     4321 ctcgctgagg aaatcagaat acagagcacc acaagctaac gaagtgactt aggaagccac
     4381 caaagttcat gagagccagg atcacgaccc acatctcaaa acttttaccg cgtatgcctc
     4441 ctccgtgcaa tcaggaggac ccttcacaaa ggactctggg gccacacagt gaacaggaat
     4501 actgtcaggc aatctcagaa ctccccagtg agttaaggaa aatggccact taccgtaagc
     4561 ccgttgtcct ttctcagtcc aggactgtgt tccttaaata tgtcatagag gaagaatgtc
     4621 tgtcctcagc agcctggtcc cgtctcagac tttccagaga ttaagttgcc tgtggtagga
     4681 acactcccgg ctgtggcact taaccaccgc agaacgtgat ggagcgactg agtgggatgc
     4741 agagaagctg gaatttttcg ctggcatcct aactttacag taaaagtgat gtcgcttgag
     4801 agaaggtggt accctcggtg ccggcttgca cactagctga agtaacgggt gccagctgag
     4861 acatttctgc agaccgaaaa ccttattgtg cccagagaaa aactgtttag aatcccgtta
     4921 tcacggtctc taattttgat ctctgcagcg gaatgtttta gggcacttgg cttcaaaact
     4981 gaagaaatcc gcatttcgat aggcagtctc tacccaaacc cttttcattt tttaaggcat
     5041 atgtgtttgt ttgtttgttt gtttgtttgt tttcaggatc aagaagtctg agctagcttt
     5101 aagcagcaaa ctgatttata tatgcaattt taggatgcag taagatggag gatagccttc
     5161 ttatgtgtga gacgctttta ctgcacatgt tctgttcgga gaatagcttt gcgtactaag
     5221 tgcaggttga tttttttttt tttttggtaa aatgaattat gttaaacaat atgttcagac
     5281 actttctgcc atggccaaaa agtatgtatg gaagtctgtt tgtatttgtc tgtgagagga
     5341 tgctgatgtt ttacctgagg tctctgtgat actttcgtta cctatgcatt ctttatatcc
     5401 gtggttcggt aaacaggcag ccatgttcac gatgccttgt gtgtcttatc tttttttttt
     5461 ttttttaatt aacctgttaa atacagcttg aaatattttt attttattta ttctattttt
     5521 actgaaatat actgcattat tgtgttgctg tattatcttt actgggtatg atgtccttgt
     5581 atccaggtct taaagtaact cagtgaacta tatccatcgc ctgaaaggtg gtttggtgat
     5641 ggtttgcagt cacatttctg ttggaatatg tagaaggtaa aatgcttaaa gttcctctta
     5701 ttttttgaaa gcagatagat agatgcaccc ttaccacctt atctgcgtgc cccttggaag
     5761 catctagggg gcagccgaca tgccgtctgg cgaagacctc tactttgtag actaaggcac
     5821 tgtgcggtgc ttcgttttta tatcttcaca acacgtgtga tttcatcaaa aatatacaca
     5881 gagccacatg cccttcgtct ctgcctggac tcaaggccac ccatagctaa ctagagccac
     5941 tgttttgttt atttgtctgt ctgtcttact gcacgaaggg acattaggcc cacttccatt
     6001 aaagcaaatt cttggtgata caactgttgg cactgctaat tttttttctt ttttttttta
     6061 atccacatta ggtgtttaag aaggacacat aacaaactac tcaaaactgg gcctcttaac
     6121 ttgcagcccc caaaactccc ctgagtgtgt ggcacattcg ctttatgaac attgcaacac
     6181 aagactccag aaaccacgtc tccctgacat cagcacagtt taatgaaacc aaaagctctc
     6241 tagttggccc agtttaacct aacatctgat gtgtttacag ccagttaaaa aaaaaaagta
     6301 attggacctg tttcagcatg ctggcagtgt ggcccagtgg cacggctctt gtacaacatg
     6361 cagggatctg tgtttagtcc ctgaaaagtg tcaggggaaa ggttggcact gcaaggcggt
     6421 gaagacatcg ccaggcagcc acatcggcca cttcctcctg gaaagacatc ttgtttcttt
     6481 gtgttgccat ttgctgttga ctgtgtttac acattttcat gtaaaatgtc ctgggaataa
     6541 atgtaactgc ataaaatctt tgactccttg atctgacagc atatataaga aacaaataca
     6601 aatttaatgt ctctgcagta attttatttt ctgtattatt cttacttcaa attaaacctt
     6661 taaaaaaatc a
//
