LOCUS       NM_007460               4816 bp    mRNA    linear   ROD 08-FEB-2024
DEFINITION  Mus musculus adaptor-related protein complex 3, delta 1 subunit
            (Ap3d1), mRNA.
ACCESSION   NM_007460
VERSION     NM_007460.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4816)
  AUTHORS   Xu,H., Oses-Prieto,J.A., Khvotchev,M., Jain,S., Liang,J.,
            Burlingame,A. and Edwards,R.H.
  TITLE     Adaptor protein AP-3 produces synaptic vesicles that release at
            high frequency by recruiting phospholipid flippase ATP8A1
  JOURNAL   Nat Neurosci 26 (10), 1685-1700 (2023)
   PUBMED   37723322
REFERENCE   2  (bases 1 to 4816)
  AUTHORS   Frohne,A., Koenighofer,M., Cetin,H., Nieratschker,M., Liu,D.T.,
            Laccone,F., Neesen,J., Nemec,S.F., Schwarz-Nemec,U., Schoefer,C.,
            Avraham,K.B., Frei,K., Grabmeier-Pfistershammer,K., Kratzer,B.,
            Schmetterer,K., Pickl,W.F. and Parzefall,T.
  TITLE     A homozygous AP3D1 missense variant in patients with sensorineural
            hearing loss as the leading manifestation
  JOURNAL   Hum Genet 142 (8), 1077-1089 (2023)
   PUBMED   36445457
  REMARK    GeneRIF: A homozygous AP3D1 missense variant in patients with
            sensorineural hearing loss as the leading manifestation.
REFERENCE   3  (bases 1 to 4816)
  AUTHORS   Fang,L., Xu,X., Lu,Y., Wu,Y. and Li,J.
  TITLE     Long noncoding RNA SNHG8 accelerates acute gouty arthritis
            development by upregulating AP3D1 in mice
  JOURNAL   Bioengineered 12 (2), 9803-9815 (2021)
   PUBMED   34874227
  REMARK    GeneRIF: Long noncoding RNA SNHG8 accelerates acute gouty arthritis
            development by upregulating AP3D1 in mice.
REFERENCE   4  (bases 1 to 4816)
  AUTHORS   Tower-Gilchrist,C., Zlatic,S.A., Yu,D., Chang,Q., Wu,H., Lin,X.,
            Faundez,V. and Chen,P.
  TITLE     Adaptor protein-3 complex is required for Vangl2 trafficking and
            planar cell polarity of the inner ear
  JOURNAL   Mol Biol Cell 30 (18), 2422-2434 (2019)
   PUBMED   31268833
REFERENCE   5  (bases 1 to 4816)
  AUTHORS   Segeletz,S., Danglot,L., Galli,T. and Hoflack,B.
  TITLE     ARAP1 Bridges Actin Dynamics and AP-3-Dependent Membrane Traffic in
            Bone-Digesting Osteoclasts
  JOURNAL   iScience 6, 199-211 (2018)
   PUBMED   30240610
REFERENCE   6  (bases 1 to 4816)
  AUTHORS   Charles,C.H., Abler,A.S. and Lau,L.F.
  TITLE     cDNA sequence of a growth factor-inducible immediate early gene and
            characterization of its encoded protein
  JOURNAL   Oncogene 7 (1), 187-190 (1992)
   PUBMED   1741163
REFERENCE   7  (bases 1 to 4816)
  AUTHORS   Swank,R.T., Reddington,M., Howlett,O. and Novak,E.K.
  TITLE     Platelet storage pool deficiency associated with inherited
            abnormalities of the inner ear in the mouse pigment mutants muted
            and mocha
  JOURNAL   Blood 78 (8), 2036-2044 (1991)
   PUBMED   1912584
REFERENCE   8  (bases 1 to 4816)
  AUTHORS   Noebels,J.L. and Sidman,R.L.
  TITLE     Persistent hypersynchronization of neocortical neurons in the mocha
            mutant of mouse
  JOURNAL   J Neurogenet 6 (1), 53-56 (1989)
   PUBMED   2778559
REFERENCE   9  (bases 1 to 4816)
  AUTHORS   Rolfsen,R.M. and Erway,L.C.
  TITLE     Trace metals and otolith defects in mocha mice
  JOURNAL   J Hered 75 (3), 159-162 (1984)
   PUBMED   6736600
REFERENCE   10 (bases 1 to 4816)
  AUTHORS   Lane,P.W. and Deol,M.S.
  TITLE     Mocha, a new coat color and behavior mutation on chromosome 10 of
            the mouse
  JOURNAL   J Hered 65 (6), 362-364 (1974)
   PUBMED   4448900
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ131283.1, BC053066.1 and AC152410.6.
            
            [WARNING] On Mar 11, 2024 this sequence was replaced by
            NM_007460.3.
            
            On Mar 28, 2018 this sequence version replaced NM_007460.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048786.1, AB004305.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                CJ131283.1         1-48
            49-4813             BC053066.1         1-4765
            4814-4816           AC152410.6         133148-133150       c
FEATURES             Location/Qualifiers
     source          1..4816
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..4816
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /note="adaptor-related protein complex 3, delta 1 subunit"
                     /db_xref="GeneID:11776"
                     /db_xref="MGI:MGI:107734"
     exon            1..380
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     CDS             285..3884
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /note="adaptor-related protein complex 3, delta subunit;
                     delta-adaptin; AP-3 complex subunit delta; adapter-related
                     protein complex 3 subunit delta-1; adaptor-related protein
                     complex AP-3, delta subunit; adaptor-related protein
                     complex 3 subunit delta-1"
                     /codon_start=1
                     /product="AP-3 complex subunit delta-1"
                     /protein_id="NP_031486.1"
                     /db_xref="CCDS:CCDS35984.1"
                     /db_xref="GeneID:11776"
                     /db_xref="MGI:MGI:107734"
                     /translation="MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIK
                     QELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRVGYLAASQCF
                     HEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKP
                     YIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNY
                     LSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLL
                     YECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTH
                     PKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTY
                     RDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKA
                     IRKFAVSQMSSLLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLR
                     PKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADTEAAQEVTQLLVERLPQFVQSADL
                     EVQERASCILQLVKHVQKLQAKGVPVAEEVSALFAGELNPVAPKAQKKVPVPEGLDLD
                     AWINEPPSDSESEDEKPKAIFHEEEPRHTRRRQPEEDEEELARRREARKQEQANNPFY
                     IKSSPSPQKRYQDAPGVEHIPVVQIDLSVPLKVPGMPMSDQYVKLEEQRRHRQRLEKD
                     KKRKKKEKGKRRHSSLPTESDEDIAPAQRVDIITEEMPENALPSDEDDKDPNDPYRAL
                     DIDLDKPLADSEKLPVQKHRNAEAVKSPEKEGVLGVEKKSKKPKKKEKKTKEREREKK
                     DKKGEDLDFWLSTTPPPAAAPIPAPSTEELAASTITSPKDECEVLKGEEEDHVDHDQE
                     RKSSRHKKKKHRKEKEKEERPRDKKKAKKKQVAPLENGAAAEEEEEPIPPMSSYCLLA
                     ESPYIKVTYDIQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMTRPEGSSV
                     HDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLDFRLHF
                     SCSSYLITTPCYSDAFAKLLESGDLSMNSIKVDGISMSFQNLLAKICFYHHFSVVERV
                     DSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKTTLAQC"
     exon            381..476
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            477..557
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            558..638
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            639..746
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            747..876
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            877..1016
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1090
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1140
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1190
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1239
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1385
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1765
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            1766..1997
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2143
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            2144..2285
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            2286..2357
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            2358..2433
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            2434..2621
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            2622..2695
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            2696..2861
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..2933
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            2934..3029
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            3030..3173
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            3174..3221
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            3222..3411
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            3412..3500
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            3501..3586
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            3587..3708
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            3709..3788
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
     exon            3789..4816
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d; Bolvr; mBLVR1; mh; mocha"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgaggctctc cgtcagctga cccaccgcca tcttggccgc catttgcagc ggccctaagc
       61 tgggaagggt ctgtggaagc tggggggggc gggcttactg gctacccctt ctcctcagac
      121 tgctctccgg ctacagccgt cgctctggcc tccacggcgt cccctccgcg gcggccggaa
      181 acacagcggg gcggttgcct gaggtgcggt cgccgggtcc ccgcaccttc tagggccgcg
      241 gcagcggcgt ttccctcgga ggccgcagcc cacgggccgc cgcgatggcc ctcaagatgg
      301 tcaagggcag tatcgaccgc atgttcgata agaacctgca ggatctggtc cgcggcatcc
      361 gcaaccacaa ggaggacgag gccaagtaca tctcccagtg cattgacgag atcaagcagg
      421 agctgaagca ggacaacatc gctgtgaagg ccaacgctgt ctgcaagctc acctacttac
      481 agatgcttgg gtacgacatc agctgggctg ccttcaacat cattgaagtc atgagtgcct
      541 ccaagttcac attcaagcgt gttggctacc ttgcggcctc ccagtgcttc catgaaggta
      601 ccgacgtcat catgctgacc accaaccaga tccgaaagga cctgagcagc cccagccagt
      661 acgacactgg agtggcactg actggtctgt cctgttttgt caccccagat cttgccagag
      721 acctggcaaa tgacatcatg accctgatgt ctcacacgaa gccgtacatc aggaagaagg
      781 cagtgctgat catgtacaaa gtattcctca agtacccaga gtcgctgcgt cctgcctttc
      841 cccggcttaa ggagaagctg gaggacccag acccaggggt acagtctgcg gctgttaatg
      901 tcatctgcga gctggcacgc cgcaacccta aaaactacct gtctctggcg ccactgtttt
      961 tcaagctcat gacatcctcc accaacaact gggtcctcat caagatcatc aagctgttcg
     1021 gtgccctgac tcctctggag cccaggctgg gcaagaagct gatcgagcct ctcaccaacc
     1081 tcattcacag cacctctgcc atgtccctgc tgtacgagtg tgtgaacacc gtaattgctg
     1141 tgctcatctc actgtcttct gggatgccca accacagcgc cagcatccag ctatgcgttc
     1201 agaagttgag gatactgata gaagactccg accagaactt aaagtacctg gggctgctgg
     1261 ccatgtctaa aatcctgaag acacacccca agtctgtgca gtcccacaag gacctgatcc
     1321 tgcagtgcct ggatgacaag gacgagtcca tccgcctgcg tgcacttgac ctgctctatg
     1381 gaatggtgtc caagaagaac ctgatggaga ttgtgaagaa gctcatgact cacgtggaca
     1441 aggctgaggg caccacctat cgcgatgaac tgctcaccaa gatcattgac atctgtagcc
     1501 agtccaacta ccagcacatc accaacttcg agtggtacat cagcatcctt gtggagctga
     1561 caaggctgga gggcacccgc catggccacc tcattgctgc acagatgctg gacgtggcta
     1621 tccgggtcaa ggccattcgc aaatttgctg tgtcgcagat gtcctcactg cttgacagtg
     1681 ctcacctggt agccagcagc acccaacgca atggtatctg tgaggtgctc tatgctgctg
     1741 cctggatctg cggggagttc tcagagcacc tacaggggcc ccagcaaacc ctggaggcca
     1801 tgctgcggcc caaggtcacc acactgcccg gccatatcca ggctgtgtat gtgcagaacg
     1861 tggtaaagct gtacgcgtcc atcctgcagc agaaggagca ggccgctgac actgaggctg
     1921 cacaagaggt cacccagcta ctggtggagc gactgccaca gtttgtgcag agcgccgacc
     1981 tggaggtgca ggagcgggcg tcttgcatcc tgcagctggt caagcatgtc cagaagctgc
     2041 aagcaaaagg tgtgccggtg gctgaggaag tgagcgcctt gtttgctggt gaactgaacc
     2101 ctgtggcccc caaggctcag aaaaaggtcc cagttcctga aggcctagac ctggatgcct
     2161 ggatcaatga gccaccttca gacagtgagt ctgaggatga gaaacccaag gccatcttcc
     2221 atgaagaaga gccgaggcac actcggcgcc ggcagcctga ggaggatgaa gaggagctgg
     2281 ctcggcggcg agaggcccgg aagcaggaac aagccaacaa ccccttctac atcaagagct
     2341 ccccatcccc gcagaagcga taccaggatg caccaggtgt ggaacacatt cctgtggtac
     2401 agatcgacct ctcagtgcct ctgaaagttc caggtatgcc catgtcagac cagtatgtga
     2461 agctggagga gcagcggcga caccggcagc ggctggagaa ggacaagaaa aggaagaaga
     2521 aggagaaggg caagcggcgc cacagctctc tccccacgga gagcgatgag gacattgccc
     2581 ctgcccagcg tgtggacatt atcactgagg agatgccaga gaatgctttg cctagtgacg
     2641 aggatgacaa agaccccaat gacccctaca gggcgctgga cattgacctg gataaacccc
     2701 tggctgacag tgagaagctg cctgtccaga aacatagaaa tgcggaggcg gtgaagtccc
     2761 cagagaagga gggtgtgctc ggggtagaga agaagagcaa gaagcccaag aagaaggaga
     2821 agaagaccaa agagagagag agagagaaga aggacaagaa gggtgaggac ttagacttct
     2881 ggctgtccac caccccacca cctgctgctg cccccattcc tgccccgtcc acggaagaac
     2941 ttgctgcaag cactatcacc tcccctaagg atgagtgtga ggttctcaaa ggggaagagg
     3001 aggaccacgt ggatcatgac caagaaagga aatcatcccg gcacaagaag aagaaacaca
     3061 gaaaggagaa ggagaaggag gagaggccac gagacaagaa gaaagctaag aagaagcagg
     3121 tggcacctct ggagaatggt gcggcagcag aggaggagga ggagcctatc ccgcccatgt
     3181 ccagctactg ccttctggct gagagtccct acattaaagt gacatatgac atccaagcca
     3241 gcttacagaa ggacagccaa gtgactgtgt ccatcatcct ggagaaccag agcagcagct
     3301 tcctgaagaa catggagctc aacgtgctgg actctctcaa caccaagatg accaggccag
     3361 agggctcatc ggtacacgac ggtgtgcccg tgcctttcca actgcctccc ggcgtctcca
     3421 atgaggccca gtttgtgttc accattcaga gcatcgtcat ggcccagaag ctcaaaggca
     3481 cactgtcctt cattgccaag gatgatgaag gagccaccca tgagaagttg gacttccggc
     3541 tgcatttcag ctgtagctcg tacctgatca ccacaccctg ctacagcgat gcctttgcaa
     3601 agttgctaga gtcaggagac ctgagcatga actccatcaa agtcgatggc attagtatgt
     3661 ctttccagaa tcttctggca aagatctgct tctaccacca tttttccgtt gtggagcgag
     3721 tagactcctg tgcctccatg tacagccgct ctatccaggg ccaccatgtc tgcctgctgg
     3781 tgaagaaggg cgagagctcc gtgtcagtag atgggaagtg cagcgatgcc acgttgctca
     3841 gcagcctgct ggaggaaatg aagaccacgt tggctcagtg ctgagttgca gtccaggatg
     3901 tgcaacagac cacagaaaga tgtgatgcgt cttacctctc ctgttgtgtg tactgtctca
     3961 cacccagcat taatttaaca ccaccggcct ccactgtgtg accctgaggt cctatgttgc
     4021 atcaacttct tttattatcc tttattccga cctgcactcc tttagcaagg aaggccatcc
     4081 tgaccctagc cagaaagggg ctgctccact tcccattctc aaaggcggct gtggactgca
     4141 gggttacagc aaacacactg atgtggcccc actcctgacc ccatgctgcc tctggaggaa
     4201 cccttccaga tgctgctgtc cacaaatatt ccaactggta gcctctatgg agaggtgata
     4261 aggccagctg ttaatgcttt tccccacagc ctgcaaggtc agatggatga agtgtccttg
     4321 tgggtggctc cgcagctcag ctgcagacaa cagggatggc cctttgattt tcttctgttc
     4381 aacagaactg tggtctgtct tggggttctg ttgtgggggt cagtggaaga gtgcaatgta
     4441 tgcctcagtt tgtcactaca catcatgggc ttgtccctgc agctgtggag ggcttagtgc
     4501 cttgcagtgg agagtgtgca tcctgggagc agtcagtgct tccccagctg ttcctgggta
     4561 aggtgaagag acatctaact gggtagctgg gcacaagctg agccttcctc agaggtgaca
     4621 gtggtctaca gacattctgg cttcctttga ggacaactgt cactttagca tgtagagtac
     4681 tcttaccgac cccatgtgac cttccagctc tatgatgttc catgattgat ttgctgttga
     4741 cattcccatg tgaagagaga tatatcacgc tgctgacgat cggtgtcaca atgacccatt
     4801 aaagagtcaa aaaaca
//
