LOCUS       NM_007457               1350 bp    mRNA    linear   ROD 18-DEC-2022
DEFINITION  Mus musculus adaptor protein complex AP-1, sigma 1 (Ap1s1), mRNA.
ACCESSION   NM_007457
VERSION     NM_007457.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Candiello E, Kratzke M, Wenzel D, Cassel D and Schu P.
  TITLE     AP-1/sigma1A and AP-1/sigma1B adaptor-proteins differentially
            regulate neuronal early endosome maturation via the
            Rab5/Vps34-pathway
  JOURNAL   Sci Rep 6, 29950 (2016)
   PUBMED   27411398
  REMARK    GeneRIF: AP-1/sigma1A-ArfGAP1-Rabex-5 complex formation leads to
            more endosomal Rabex-5 and enhanced, Rab5(GTP)-stimulated Vps34
            PI3-kinase activity, which is essential for multivesicular body
            endosome formation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  AUTHORS   Folsch H.
  TITLE     Role of the epithelial cell-specific clathrin adaptor complex AP-1B
            in cell polarity
  JOURNAL   Cell Logist 5 (2), e1074331 (2015)
   PUBMED   27057418
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1350)
  AUTHORS   Baltes J, Larsen JV, Radhakrishnan K, Geumann C, Kratzke M,
            Petersen CM and Schu P.
  TITLE     sigma1B adaptin regulates adipogenesis by mediating the sorting of
            sortilin in adipose tissue
  JOURNAL   J Cell Sci 127 (Pt 16), 3477-3487 (2014)
   PUBMED   24928897
REFERENCE   4  (bases 1 to 1350)
  AUTHORS   Moreno E, Moreno-Delgado D, Navarro G, Hoffmann HM, Fuentes S,
            Rosell-Vilar S, Gasperini P, Rodriguez-Ruiz M, Medrano M, Mallol J,
            Cortes A, Casado V, Lluis C, Ferre S, Ortiz J, Canela E and
            McCormick PJ.
  TITLE     Cocaine disrupts histamine H3 receptor modulation of dopamine D1
            receptor signaling: sigma1-D1-H3 receptor complexes as key targets
            for reducing cocaine's effects
  JOURNAL   J Neurosci 34 (10), 3545-3558 (2014)
   PUBMED   24599455
REFERENCE   5  (bases 1 to 1350)
  AUTHORS   Bultema JJ and Di Pietro SM.
  TITLE     Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous
            lysosome biogenesis machinery to synthesize specialized
            lysosome-related organelles
  JOURNAL   Small GTPases 4 (1), 16-21 (2013)
   PUBMED   23247405
  REMARK    Review article
REFERENCE   6  (bases 1 to 1350)
  AUTHORS   Takatsu H, Sakurai M, Shin HW, Murakami K and Nakayama K.
  TITLE     Identification and characterization of novel clathrin
            adaptor-related proteins
  JOURNAL   J Biol Chem 273 (38), 24693-24700 (1998)
   PUBMED   9733768
REFERENCE   7  (bases 1 to 1350)
  AUTHORS   Odorizzi G, Cowles CR and Emr SD.
  TITLE     The AP-3 complex: a coat of many colours
  JOURNAL   Trends Cell Biol 8 (7), 282-288 (1998)
   PUBMED   9714600
  REMARK    Review article
REFERENCE   8  (bases 1 to 1350)
  AUTHORS   Paradis P, MacLellan WR, Belaguli NS, Schwartz RJ and Schneider MD.
  TITLE     Serum response factor mediates AP-1-dependent induction of the
            skeletal alpha-actin promoter in ventricular myocytes
  JOURNAL   J Biol Chem 271 (18), 10827-10833 (1996)
   PUBMED   8631897
REFERENCE   9  (bases 1 to 1350)
  AUTHORS   Foletta VC.
  TITLE     Transcription factor AP-1, and the role of Fra-2
  JOURNAL   Immunol Cell Biol 74 (2), 121-133 (1996)
   PUBMED   8723999
  REMARK    Review article
REFERENCE   10 (bases 1 to 1350)
  AUTHORS   Kirchhausen T, Davis AC, Frucht S, Greco BO, Payne GS and Tubb B.
  TITLE     AP17 and AP19, the mammalian small chains of the
            clathrin-associated protein complexes show homology to Yap17p,
            their putative homolog in yeast
  JOURNAL   J Biol Chem 266 (17), 11153-11157 (1991)
   PUBMED   2040623
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY253222.1 and BC052692.1.
            
            [WARNING] On May 5, 2023 this sequence was replaced by NM_007457.4.
            
            On Mar 28, 2018 this sequence version replaced NM_007457.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052692.1, M62418.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-44                BY253222.1         1-44
            45-1350             BC052692.1         1-1306
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5"
     gene            1..1350
                     /gene="Ap1s1"
                     /gene_synonym="AP19"
                     /note="adaptor protein complex AP-1, sigma 1"
                     /db_xref="GeneID:11769"
                     /db_xref="MGI:MGI:1098244"
     exon            1..101
                     /gene="Ap1s1"
                     /gene_synonym="AP19"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..575
                     /gene="Ap1s1"
                     /gene_synonym="AP19"
                     /note="sigma1A-adaptin; sigma-adaptin 1A; HA1 19 kDa
                     subunit; sigma 1a subunit of AP-1 clathrin; clathrin coat
                     assembly protein AP19; adaptor protein complex AP-1
                     sigma-1A subunit; golgi adaptor HA1/AP1 adaptin sigma-1A
                     subunit; adapter-related protein complex 1 sigma-1A
                     subunit; clathrin assembly protein complex 1 sigma-1A
                     small chain; adaptor-related protein complex AP-1, sigma
                     1; adaptor protein complex AP-1 subunit sigma-1A;
                     adapter-related protein complex 1 subunit sigma-1A;
                     adaptor-related protein complex 1 subunit sigma-1A"
                     /codon_start=1
                     /product="AP-1 complex subunit sigma-1A"
                     /protein_id="NP_031483.1"
                     /db_xref="CCDS:CCDS39330.1"
                     /db_xref="GeneID:11769"
                     /db_xref="MGI:MGI:1098244"
                     /translation="MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKP
                     KMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELD
                     IIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA"
     exon            102..280
                     /gene="Ap1s1"
                     /gene_synonym="AP19"
                     /inference="alignment:Splign:2.1.0"
     exon            281..389
                     /gene="Ap1s1"
                     /gene_synonym="AP19"
                     /inference="alignment:Splign:2.1.0"
     exon            390..527
                     /gene="Ap1s1"
                     /gene_synonym="AP19"
                     /inference="alignment:Splign:2.1.0"
     exon            528..1321
                     /gene="Ap1s1"
                     /gene_synonym="AP19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttcaagcgga gagggaggga aaagaaaaga atccgactgg gagtggagct ggcttctacg
       61 gtggccggag agggacgcac cgggctggag gctgcaggat gatgcgattc atgctactgt
      121 tcagccggca gggaaaactt cggctacaaa aatggtacct ggccacctca gacaaggaga
      181 ggaagaagat ggtccgagag ctcatgcaag tcgtcctggc tagaaagccc aaaatgtgca
      241 gcttcctgga gtggagggac ctcaaagttg tctataagag atacgccagt ctctatttct
      301 gctgcgccat cgaaggccaa gacaacgagc tgatcacact ggagctgatc caccgatacg
      361 tagagctctt ggacaagtac ttcggcagcg tatgtgagtt ggacatcatc ttcaactttg
      421 agaaagccta ctttatcctg gacgagtttc tgatgggtgg ggatgtccag gacacctcca
      481 agaagagtgt gctcaaggcc attgagcagg ctgacctgct gcaggaggag gatgagtcgc
      541 cgcgcagtgt cctggaggag atgggcctgg catagccccg tcagccagcg gggggccctg
      601 tggaccgggg gaagacaaga caagacagca cttgggggct gtttctctca cctctccccc
      661 agaccccttc tcttggaggg actcggctgc ttttcctcgg ccaccttacc tactttagaa
      721 ggagctgtgg ctccggccct tcgtacaaac attccctcct tccaaatctc ccttccctcc
      781 accctctacc tctcccagcg aaggttttag gatctagaag ggaggaaaaa cgtgacctgg
      841 atgggggtgc tcagtggctt ccattttcct tcctttgaag aagcattgtt gagcccagcc
      901 atccctcgcc ctccatgtgc cctgtatggc tgtaaatata taaatacgtc aggttaaagg
      961 gaaaaggttt ccagggctct tttctctcct ctgccccaaa acctacctcc acgcctcccc
     1021 ataaccagcc agggcagctt ctctgcctgg gaggggcttt gtcctctcca gcccccactt
     1081 cctcctgggc tccagtgtcc agccagggcc agggaaggga gccacagagt taacgttttt
     1141 ctaaccttgc tacttggagg gaagggaagg ttgggggaga ggcctgcttt ctgggacact
     1201 gaccctgtcc cctttcctcc actccacggt gagggtgcgg caggagccaa gcaggtggca
     1261 tgggccaagt ggctgccttt atctcctttc ttctgaaata aaaggaaaaa gtgtttctgg
     1321 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
