LOCUS       NM_023631               4976 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus aldehyde oxidase 4 (Aox4), mRNA.
ACCESSION   NM_023631
VERSION     NM_023631.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4976)
  AUTHORS   Terao,M., Barzago,M.M., Kurosaki,M., Fratelli,M., Bolis,M.,
            Borsotti,A., Bigini,P., Micotti,E., Carli,M., Invernizzi,R.W.,
            Bagnati,R., Passoni,A., Pastorelli,R., Brunelli,L., Toschi,I.,
            Cesari,V., Sanoh,S. and Garattini,E.
  TITLE     Mouse aldehyde-oxidase-4 controls diurnal rhythms, fat deposition
            and locomotor activity
  JOURNAL   Sci Rep 6, 30343 (2016)
   PUBMED   27456060
  REMARK    GeneRIF: Deletion of the Aox4 gene causes perturbations in diurnal
            rhythms, fat deposition and locomotor activity.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4976)
  AUTHORS   Cerqueira,N.M., Coelho,C., Bras,N.F., Fernandes,P.A., Garattini,E.,
            Terao,M., Romao,M.J. and Ramos,M.J.
  TITLE     Insights into the structural determinants of substrate specificity
            and activity in mouse aldehyde oxidases
  JOURNAL   J Biol Inorg Chem 20 (2), 209-217 (2015)
   PUBMED   25287365
  REMARK    GeneRIF: Although mAOX2 and mAOX3 are very similar to each other,
            we propose the following pairs of overlapping substrate
            specificities: mAOX2/mAOX4 and mAOX3/mAXO1.
REFERENCE   3  (bases 1 to 4976)
  AUTHORS   Kurosaki,M., Bolis,M., Fratelli,M., Barzago,M.M., Pattini,L.,
            Perretta,G., Terao,M. and Garattini,E.
  TITLE     Structure and evolution of vertebrate aldehyde oxidases: from gene
            duplication to gene suppression
  JOURNAL   Cell Mol Life Sci 70 (10), 1807-1830 (2013)
   PUBMED   23263164
REFERENCE   4  (bases 1 to 4976)
  AUTHORS   Terao,M., Kurosaki,M., Barzago,M.M., Fratelli,M., Bagnati,R.,
            Bastone,A., Giudice,C., Scanziani,E., Mancuso,A., Tiveron,C. and
            Garattini,E.
  TITLE     Role of the molybdoflavoenzyme aldehyde oxidase homolog 2 in the
            biosynthesis of retinoic acid: generation and characterization of a
            knockout mouse
  JOURNAL   Mol Cell Biol 29 (2), 357-377 (2009)
   PUBMED   18981221
  REMARK    GeneRIF: data indicate a significant role of AOH2 in the local
            synthesis and biodisposition of endogenous retinoids in the
            Harderian gland and skin
REFERENCE   5  (bases 1 to 4976)
  AUTHORS   Kurosaki,M., Terao,M., Barzago,M.M., Bastone,A., Bernardinello,D.,
            Salmona,M. and Garattini,E.
  TITLE     The aldehyde oxidase gene cluster in mice and rats. Aldehyde
            oxidase homologue 3, a novel member of the molybdo-flavoenzyme
            family with selective expression in the olfactory mucosa
  JOURNAL   J Biol Chem 279 (48), 50482-50498 (2004)
   PUBMED   15383531
REFERENCE   6  (bases 1 to 4976)
  AUTHORS   Terao,M., Kurosaki,M., Marini,M., Vanoni,M.A., Saltini,G.,
            Bonetto,V., Bastone,A., Federico,C., Saccone,S., Fanelli,R.,
            Salmona,M. and Garattini,E.
  TITLE     Purification of the aldehyde oxidase homolog 1 (AOH1) protein and
            cloning of the AOH1 and aldehyde oxidase homolog 2 (AOH2) genes.
            Identification of a novel molybdo-flavoprotein gene cluster on
            mouse chromosome 1
  JOURNAL   J Biol Chem 276 (49), 46347-46363 (2001)
   PUBMED   11562361
REFERENCE   7  (bases 1 to 4976)
  AUTHORS   Terao,M., Kurosaki,M., Saltini,G., Demontis,S., Marini,M.,
            Salmona,M. and Garattini,E.
  TITLE     Cloning of the cDNAs coding for two novel molybdo-flavoproteins
            showing high similarity with aldehyde oxidase and xanthine
            oxidoreductase
  JOURNAL   J Biol Chem 275 (39), 30690-30700 (2000)
   PUBMED   10893244
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK158427.1, AC025116.14 and AI414378.1.
            
            On Sep 8, 2006 this sequence version replaced NM_023631.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF233581.1, BC117975.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4303              AK158427.1         2-4304
            4304-4609           AC025116.14        8493-8798           c
            4610-4976           AI414378.1         1-367               c
FEATURES             Location/Qualifiers
     source          1..4976
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 28.97 cM"
     gene            1..4976
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /note="aldehyde oxidase 4"
                     /db_xref="GeneID:71872"
                     /db_xref="MGI:MGI:1919122"
     exon            1..232
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..4189
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /EC_number="1.2.3.1"
                     /note="aldehyde oxidase structural homolog 2; retinal
                     oxidase; aldehyde oxidase homolog 2; azaheterocycle
                     hydroxylase 4"
                     /codon_start=1
                     /product="aldehyde oxidase 4"
                     /protein_id="NP_076120.2"
                     /db_xref="CCDS:CCDS14970.1"
                     /db_xref="GeneID:71872"
                     /db_xref="MGI:MGI:1919122"
                     /translation="MPSVSESDELIFFVNGKKVIEKNPDPEKNLLFYTRKVLNLTGTK
                     YSCGTGGCGACTVMVSRYNPKTRKIHHYPATACLVPICWLHGAAITTVEGVGSIKKRV
                     HPVQERLAKCHGTQCGFCSPGMVMSIYTLLRNHPEPTPDQITEALGGNLCRCTGYRPI
                     VESGKTFSQKSTVCQMKGSGKCCMDPDEKCLESREKKMCTKLYNEDEFQPFDPSQEPI
                     FPPELIRMAEDPNKRRLTFQGKRTTWIIPVTLNDLLELKASYPEAPLVMGNTTVGPGI
                     KFNDEFYPVFISPLGVPELNLMDTTNNGVTIGAGYSLAQLKDTLDFLVSEQPKEKTKT
                     FHALQKHLRTLAGPQIRNMATLGGHTASRPNFSDLNPILAAGNATINVVSREGKDRQL
                     PLNGPFLEKLPEADLKPEEVILSIFIPYTAQWQFVSGLRLAQRQENAFAIVNAGMSVE
                     FEEGTNTIKDLKMFFGSVAPTVVSASQTCKQLIGRQWDDQMLSDACQLVLQEIRIPPD
                     AEGGMVEYRRTLIISLLFKFYLKVQRWLNEMDPQKFPDIPGKFVSALDDFPIETPQGI
                     QMFQCVDPKQPQKDPVGHPIMHQSGIKHATGEAIFIDDMPPIDQELCLAVVTSTRAHA
                     KITSLDVSEALACPGVVDVITAEDVPGENDHNGEILYAQSEVICVGQIICTVAADTYI
                     HAKEAAKRVKIAYDDIEPTIITIEEALEHNSFLSPEKKIEQGNVDYAFKHVDQIVEGE
                     IHVEGQEHFYMETQTILAIPQTEDKEMVLHLGTQFPTHVQEFVSAALNVPRSRIACHM
                     KRAGGAFGGKVTKPALLGAVCAVAANKTGRPIRFILERSDDMLITAGRHPLLGKYKIG
                     FMNNGEIRAADVEYYTNGGCTPDESELVIEFVVLKSENTYHIPNFRCRGRACKTNLPS
                     NTAFRGFGFPQATVVVEAYIAAVASKCNLLPEEVREINMYKKTSKTAYKQTFNPEPLR
                     RCWKECLEKSSFFARKKAAEEFNGNNYWKKRGLAVVPMKFSVAVPIAFYNQAAALVHI
                     FLDGSVLLTHGGCELGQGLHTKMIQVASRELNVPKSYVHFSETSTTTVPNSAFTAGSM
                     GADINGKAVQNACQILMDRLRPIIRKNPKGKWEEWIKMAFEESISLSATGYFKGYQTN
                     MDWKKEEGDPYPYYVYGAACSEVEVDCLTGAHKLLRTDIFVDAAFSINPALDIGQVEG
                     AFIQGMGFYTTEELKYSPKGVLYSRGPEDYKIPTITEIPEEFYVTLVHSRNPIAIYSS
                     KGLGEAGMFLGSSVLFAIYDAVTTARKERGLSDIFPLNSPATPEVIRMACTDQFTEMI
                     PRDDPSTFTPWSIHVS"
     exon            233..290
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            291..387
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            388..496
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            497..623
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            624..685
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            686..769
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            770..850
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            851..995
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1088
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1240
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1334
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1447
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1632
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1795
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            1796..1888
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..2058
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            2059..2173
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            2174..2296
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            2297..2393
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            2394..2518
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            2519..2652
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            2653..2740
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            2741..2827
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            2828..3019
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3020..3247
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3248..3343
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3344..3472
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3473..3547
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3548..3600
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3601..3715
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3716..3781
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3782..3967
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3968..4135
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4136..4973
                     /gene="Aox4"
                     /gene_synonym="2310003G12Rik; Aoh2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgggctagg caggcagggc tgactataaa tcaccagtgt tgggctgtgc cgccgatttg
       61 gcttccccgg gactgcaggt gcccaagtta cagtgctgct atatgagata gaggagcaga
      121 tacccttgtc ggtagggcat ttgtttcaaa tttgtgcttc tggctcccca ttgacaccat
      181 gccttccgtc tccgagtctg acgagctgat tttttttgtg aatggaaaaa aggtcataga
      241 gaagaaccct gaccctgaaa agaatctact gttctacacc aggaaagttc tcaatctcac
      301 aggcactaag tacagctgtg gaacaggagg ctgtggggcc tgcactgtga tggtgtcgag
      361 atataatcca aagaccagga agatccacca ctacccagca acagcatgcc tggtgcccat
      421 ctgctggctt catggagcag ccattaccac agtggaaggt gtggggagca tcaaaaagag
      481 ggtgcaccca gtgcaggaac gacttgccaa gtgtcacggc acccagtgtg gcttctgcag
      541 ccctgggatg gtgatgtcca tctacacact gctcaggaac cacccggagc cgacacctga
      601 tcagatcacg gaggctcttg gagggaattt gtgccgatgc actggatatc gaccaattgt
      661 agaaagcggg aaaacattct cccagaagtc tactgtttgc caaatgaagg gatctgggaa
      721 atgctgcatg gatccagatg agaagtgttt ggagagcaga gagaaaaaga tgtgtactaa
      781 actgtataat gaagatgagt tccagccgtt tgacccatcc caggaaccta tatttcctcc
      841 tgaactgatt agaatggcag aagatccaaa caagaggagg ctgacattcc aagggaagag
      901 gaccacctgg atcatccctg tgacactgaa tgacctcctg gaactgaaag ccagctaccc
      961 cgaagcccca ctcgtcatgg ggaacaccac agtgggaccc ggtattaaat ttaatgatga
     1021 attctatcca gtttttatat ccccacttgg ggttccagaa ctaaatctta tggacaccac
     1081 aaacaatggg gtaacaatag gagcaggata cagcctggca cagcttaaag ataccttgga
     1141 ttttctggta tcagaacaac caaaggagaa gaccaaaacc tttcacgccc tccagaaaca
     1201 tctgaggaca cttgcagggc cccagattag gaatatggct actttaggag gacacactgc
     1261 aagccgtcct aatttttctg acctcaaccc tattttggca gctggaaatg ctaccatcaa
     1321 cgtggtatct agagaaggaa aagatcgtca gctcccttta aatggccctt tcctggagaa
     1381 gttgcctgag gctgacttga aaccagaaga ggttatcttg tccattttca ttccttacac
     1441 tgctcagtgg cagtttgtgt caggactccg gttggcacag cgtcaggaaa atgcctttgc
     1501 tattgtcaat gctggtatga gcgtggagtt tgaggaaggt acaaacacga tcaaggatct
     1561 taagatgttc tttggaagtg ttgcccccac tgtggtctct gcaagtcaaa cctgcaagca
     1621 gctcattggg aggcaatggg acgaccaaat gctgagtgac gcatgccagc tggtcctgca
     1681 ggagatccgc atcccaccag atgctgaggg aggcatggtg gagtaccgac gcaccctcat
     1741 catcagcttg ctcttcaaat tctacctcaa agtgcagcga tggctgaatg aaatggatcc
     1801 tcagaagttt cctgacatcc caggaaagtt tgtgagtgcc ctagatgact tccccataga
     1861 aacaccccaa ggaatccaga tgttccagtg tgtggatccc aaacaacccc agaaagatcc
     1921 agttgggcac ccaatcatgc accagtcggg tattaaacat gccacagggg aagctatatt
     1981 tattgatgac atgcctccca ttgaccaaga actctgcctt gccgttgtca cgagtaccag
     2041 ggcccatgca aagatcacat cacttgatgt atcagaagcc ctggcgtgtc caggtgtggt
     2101 tgacgtgatc acagctgagg atgtcccggg agaaaatgat cacaatggag agattcttta
     2161 tgcacagagt gaggtcattt gcgtgggtca gatcatctgc accgtggctg ctgataccta
     2221 catccatgca aaagaagcag ctaaacgagt gaagattgct tatgatgaca tagagccaac
     2281 cattatcacc atagaggaag ccctagaaca caattctttc ctttctcctg agaaaaaaat
     2341 tgaacaagga aatgtagact atgccttcaa acatgtggat caaatcgttg aaggtgagat
     2401 ccacgtggaa gggcaggaac acttttacat ggaaacgcaa accatcctgg ctatcccaca
     2461 aactgaagac aaagaaatgg tgttacactt ggggacacag tttccaaccc acgtgcagga
     2521 atttgtgtct gcagcattaa atgtcccaag gagcaggatc gcctgccaca tgaaaagagc
     2581 tggaggagca tttgggggca aagtgaccaa gcctgctcta ctgggagctg tctgtgctgt
     2641 ggctgccaac aagactggcc gcccaatccg cttcatccta gaacgaagtg atgacatgct
     2701 gataacagct ggccgccacc cactcctggg aaaatacaaa attgggttca tgaataatgg
     2761 agagatcaga gctgctgacg ttgaatatta cactaatgga ggatgcaccc ccgacgaatc
     2821 tgagctggtg atagaatttg tcgtgctgaa atctgaaaat acatatcata ttccgaattt
     2881 ccggtgccgg ggcagggctt gcaaaacaaa cttaccatct aacacggctt tccgaggatt
     2941 tggcttccct caggctacgg tggtcgtcga agcatacatc gctgcggtag catctaaatg
     3001 taacttactc cctgaagagg ttagagaaat aaacatgtat aagaaaacta gcaagacagc
     3061 ctataagcag acgtttaatc cagagccctt gcggagatgc tggaaggagt gtctggagaa
     3121 gtcgtcattc tttgctagga agaaggctgc agaggaattt aacggaaaca actattggaa
     3181 gaagaggggg cttgctgtcg tccccatgaa gttcagcgtt gcggtcccca tagccttcta
     3241 caatcaggct gctgctctgg tccacatctt cttagacggc tctgtcctgc tgacccacgg
     3301 tggctgcgag ctgggacaag gcctacacac taagatgatt caggtagcca gtagagaact
     3361 caacgtcccc aagtcgtacg tgcacttttc tgaaaccagc actaccacag tgcccaactc
     3421 cgccttcact gcgggttcca tgggagcaga tatcaatggg aaggctgtac agaatgcctg
     3481 ccagattctt atggaccgtc ttcggcccat catcaggaaa aaccctaaag gaaaatggga
     3541 ggaatggatt aaaatggcct ttgaagaatc catcagcctc tcagccactg gatatttcaa
     3601 aggctaccag acaaacatgg actggaagaa ggaggaaggt gatccctacc catactatgt
     3661 ctatggcgca gcctgctctg aggttgaagt ggactgtctg actggggctc acaagctcct
     3721 gaggaccgac atcttcgtgg atgctgcctt cagcattaac cctgccctgg atatcgggca
     3781 ggttgaggga gcctttatcc aaggcatggg attctacacc acagaggagt tgaaatactc
     3841 cccaaaaggt gtgctctatt ctcggggccc agaagactac aaaatcccca ccatcactga
     3901 gataccagag gagttctatg tcactctggt gcattctcga aatcccatag ccatctactc
     3961 atccaaggga ttgggtgagg ctgggatgtt cctggggtcc tcagttttat ttgccatata
     4021 tgatgccgtg accactgccc gcaaggagag agggctgagc gacatcttcc ccttgaatag
     4081 cccagcaaca cctgaagtga ttcgcatggc ttgtacggat cagtttactg agatgattcc
     4141 cagagatgac ccttcaacat tcacaccttg gtccatccac gtgtcttaat cttgtgtctt
     4201 taagaaaaag aaaagccatg cagcggattc aaactagccc caaaccagag cagcatatgg
     4261 gttgacgaga atttatcaaa catgatttta ctgtttttta gttattctct gtgattaggt
     4321 tattgtgtga ttacatgtta agatacagat ttctacaaaa ttgtgtggca aaacttagaa
     4381 ttggaaattc tgatttagtt ttcattgtcc tgaaagtatg catcatggtg agtttttaaa
     4441 cctagctaac taacctgggg tagctcagga gggcctcctt gtgttttgtt tcaagcagct
     4501 atgtttgaaa cccaacagag ctgtctgttc caaaactctc tctagactgg agtctcccaa
     4561 aaccagcaca cctgaaaaac ccactttcca gtgcttgcca cttcctgtgg tacagacgct
     4621 atcataagag caagcagtaa gtgctcaggg aacctggacg tagagctgga gacaggtttg
     4681 aatacagctt gtctccaaag gtgtgtgctg gaagcctggc tcccagggtg gtactgttga
     4741 aactgtaaga ggtggagcct attgagaggt cattggtaag ggatcaatgg tgacaggaag
     4801 gaatggacta gttccccaaa acctggcccc tcctcctctc tgccagtgtg agccattgca
     4861 tttctagtgt gtgatgccat ctactgggac agaaaggagg tcctcaccag atgggcagtc
     4921 ttgtgaactt gcctctaaac tatgaaccaa aataaaactc ttttcttcac aaaaaa
//
