LOCUS       NM_001409448            1076 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus annexin A4 (Anxa4), transcript variant 16, mRNA.
ACCESSION   NM_001409448
VERSION     NM_001409448.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1076)
  AUTHORS   Wilkerson,B.A., Zebroski,H.L., Finkbeiner,C.R., Chitsazan,A.D.,
            Beach,K.E., Sen,N., Zhang,R.C. and Bermingham-McDonogh,O.
  TITLE     Novel cell types and developmental lineages revealed by single-cell
            RNA-seq analysis of the mouse crista ampullaris
  JOURNAL   Elife 10, e60108 (2021)
   PUBMED   34003106
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1076)
  AUTHORS   Li,L., Zhang,R., Liu,Y. and Zhang,G.
  TITLE     ANXA4 Activates JAK-STAT3 Signaling by Interacting with ANXA1 in
            Basal-Like Breast Cancer
  JOURNAL   DNA Cell Biol 39 (9), 1649-1656 (2020)
   PUBMED   32552056
  REMARK    GeneRIF: ANXA4 Activates JAK-STAT3 Signaling by Interacting with
            ANXA1 in Basal-Like Breast Cancer.
REFERENCE   3  (bases 1 to 1076)
  AUTHORS   Heinick,A., Pluteanu,F., Hermes,C., Klemme,A., Domnik,M.,
            Husser,X., Gerke,V., Schmitz,W. and Muller,F.U.
  TITLE     Annexin A4 N-terminal peptide inhibits adenylyl cyclase 5 and
            limits beta-adrenoceptor-mediated prolongation of cardiac action
            potential
  JOURNAL   FASEB J 34 (8), 10489-10504 (2020)
   PUBMED   32579290
REFERENCE   4  (bases 1 to 1076)
  AUTHORS   McInturff,S., Burns,J.C. and Kelley,M.W.
  TITLE     Characterization of spatial and temporal development of Type I and
            Type II hair cells in the mouse utricle using new
            cell-type-specific markers
  JOURNAL   Biol Open 7 (11) (2018)
   PUBMED   30455179
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1076)
  AUTHORS   Jiang,K., Tang,Z., Li,J., Wang,F. and Tang,N.
  TITLE     Anxa4 mediated airway progenitor cell migration promotes distal
            epithelial cell fate specification
  JOURNAL   Sci Rep 8 (1), 14344 (2018)
   PUBMED   30254199
  REMARK    GeneRIF: Anxa4 mediated airway progenitor cell migration promotes
            distal epithelial cell fate specification
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1076)
  AUTHORS   Hamre,K.M., Chepenik,K.P. and Goldowitz,D.
  TITLE     The annexins: specific markers of midline structures and sensory
            neurons in the developing murine central nervous system
  JOURNAL   J Comp Neurol 352 (3), 421-435 (1995)
   PUBMED   7706559
REFERENCE   7  (bases 1 to 1076)
  AUTHORS   Patel,A., Rochelle,J.M., Jones,J.M., Sumegi,J., Uhl,G.R.,
            Seldin,M.F., Meisler,M.H. and Gregor,P.
  TITLE     Mapping of the taurine transporter gene to mouse chromosome 6 and
            to the short arm of human chromosome 3
  JOURNAL   Genomics 25 (1), 314-317 (1995)
   PUBMED   7774940
REFERENCE   8  (bases 1 to 1076)
  AUTHORS   Swaroop,A., Yang-Feng,T.L., Liu,W., Gieser,L., Barrow,L.L.,
            Chen,K.C., Agarwal,N., Meisler,M.H. and Smith,D.I.
  TITLE     Molecular characterization of a novel human gene, SEC13R, related
            to the yeast secretory pathway gene SEC13, and mapping to a
            conserved linkage group on human chromosome 3p24-p25 and mouse
            chromosome 6
  JOURNAL   Hum Mol Genet 3 (8), 1281-1286 (1994)
   PUBMED   7987303
REFERENCE   9  (bases 1 to 1076)
  AUTHORS   Barrow,L.L., Simin,K., Jones,J.M., Lee,D.C. and Meisler,M.H.
  TITLE     Conserved linkage of early growth response 4, annexin 4, and
            transforming growth factor alpha on mouse chromosome 6
  JOURNAL   Genomics 19 (2), 388-390 (1994)
   PUBMED   8188273
REFERENCE   10 (bases 1 to 1076)
  AUTHORS   Tait,J.F., Smith,C., Frankenberry,D.A., Miao,C.H., Adler,D.A. and
            Disteche,C.M.
  TITLE     Chromosomal mapping of the human annexin IV (ANX4) gene
  JOURNAL   Genomics 12 (2), 313-318 (1992)
   PUBMED   1346776
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157099.5 and AC158662.7.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY156447.1, BY217487.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                AC157099.5         131747-131782
            37-82               AC158662.7         241292-241337       c
            83-170              AC158662.7         236204-236291       c
            171-265             AC158662.7         233349-233443       c
            266-379             AC158662.7         230383-230496       c
            380-1076            AC158662.7         228727-229423       c
FEATURES             Location/Qualifiers
     source          1..1076
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 37.75 cM"
     gene            1..1076
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /note="annexin A4"
                     /db_xref="GeneID:11746"
                     /db_xref="MGI:MGI:88030"
     exon            1..36
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /inference="alignment:Splign:2.1.0"
     exon            37..82
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..478
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /note="isoform g is encoded by transcript variant 16;
                     annexin-4; annexin IV"
                     /codon_start=1
                     /product="annexin A4 isoform g"
                     /protein_id="NP_001396377.1"
                     /db_xref="GeneID:11746"
                     /db_xref="MGI:MGI:88030"
                     /translation="MEAKGGTVKAASGFNATEDAQTLRKAMKGLGTDEDAIIGILAYR
                     NTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFEQVILGLMTPTVLYDVQELRRAMKGA
                     GTDEGCLIEILASRTPEEIRRINQTYQQRK"
     exon            83..170
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /inference="alignment:Splign:2.1.0"
     exon            171..265
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /inference="alignment:Splign:2.1.0"
     exon            266..379
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /inference="alignment:Splign:2.1.0"
     exon            380..1076
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1049..1054
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /note="hexamer: AATAAA"
     polyA_site      1076
                     /gene="Anxa4"
                     /gene_synonym="AIV; Anx4; Xanx-4"
                     /note="major polyA site"
ORIGIN      
        1 attcgccgta gtctagagcc tttctccgca ccagaggaac ttctgcaggt gtgactgaac
       61 tctgaacgtg agctacagca tggaagccaa aggaggaacc gtgaaagctg cttcaggatt
      121 caacgcaact gaagatgccc agaccctgag gaaggccatg aaaggcctcg gtactgatga
      181 agatgccatt atcggaatct tagcctacag aaacaccgcc cagcgccagg agatcaggag
      241 tgcctacaag agcaccattg gcagggacct gattgaggac ttgaagtcgg agctgagcag
      301 caactttgag caggtgatcc tggggctgat gacacccaca gtgctgtatg acgtacagga
      361 gctgcggagg gccatgaagg gagctggcac ggacgagggc tgtctgattg agatcctggc
      421 ctctcgtacc cctgaggaga tccgtcgaat caaccagaca taccagcagc gtaagtagca
      481 gccccccagg ccccggccca ggttgcccag gacttgaaag gaaggctcgt gactatcact
      541 tctcagctat tagattttct cccatttgtt ttatttattt atcgtgagtg ttctgccata
      601 tctgtggcct acccgggtac tagggatgga gcccatggtc tctcacaagc caagccagct
      661 ctctagcaca gagctatacc ccatcattgc tggtctctgt gtttttaaag tcagtatgga
      721 ttgcttctga ggcaaagact gtcacacagt agggcctctt gctcagtgtt cagagcctga
      781 gcctacacct cgagggtctg gagttagagc tctgacccta gatttggagt tagtcctcta
      841 acctggaagg ttttggattt agcttccaac cctgacctta gccccatgaa ggcctctcga
      901 cctccactgc tagctgaata acaatccaag ggaagcaaga aggcagtctg attaactctg
      961 accctgaata gtttattttt ggcatattta aacacaccgc aatttggtga aaattttcct
     1021 ggtgataatt actcaatcct gtgtgtacaa taaaacttaa gatgactact tcgaaa
//
