LOCUS       NM_013470               1619 bp    mRNA    linear   ROD 16-DEC-2022
DEFINITION  Mus musculus annexin A3 (Anxa3), mRNA.
ACCESSION   NM_013470 XM_907009 XM_920152 XM_920164 XM_920172
VERSION     NM_013470.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1619)
  AUTHORS   Zhang Z, Deng M, Huang J, Wu J, Li Z, Xing M, Wang J, Guo Q and Zou
            W.
  TITLE     Microglial annexin A3 downregulation alleviates bone cancer-induced
            pain through inhibiting the Hif-1alpha/vascular endothelial growth
            factor signaling pathway
  JOURNAL   Pain 161 (12), 2750-2762 (2020)
   PUBMED   32569086
  REMARK    GeneRIF: Microglial annexin A3 downregulation alleviates bone
            cancer-induced pain through inhibiting the Hif-1alpha/vascular
            endothelial growth factor signaling pathway.
REFERENCE   2  (bases 1 to 1619)
  AUTHORS   Min XL, He M, Shi Y, Xie L, Ma XJ and Cao Y.
  TITLE     miR-18b attenuates cerebral ischemia/reperfusion injury through
            regulation of ANXA3 and PI3K/Akt signaling pathway
  JOURNAL   Brain Res Bull 161, 55-64 (2020)
   PUBMED   32380186
  REMARK    GeneRIF: miR-18b attenuates cerebral ischemia/reperfusion injury
            through regulation of ANXA3 and PI3K/Akt signaling pathway.
REFERENCE   3  (bases 1 to 1619)
  AUTHORS   Huang K, Crist AM, Patel NR, Blanks A, Carter K, Cleaver O and
            Meadows SM.
  TITLE     Annexin A3 is necessary for parallel artery-vein alignment in the
            mouse retina
  JOURNAL   Dev Dyn 249 (5), 666-678 (2020)
   PUBMED   32020697
REFERENCE   4  (bases 1 to 1619)
  AUTHORS   Mori K, Nakamura H, Kurooka H, Miyachi H, Tamada K, Sugai M, Takumi
            T and Yokota Y.
  TITLE     Id2 Determines Intestinal Identity through Repression of the
            Foregut Transcription Factor Irx5
  JOURNAL   Mol Cell Biol 38 (9), e00250-17 (2018)
   PUBMED   29463648
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1619)
  AUTHORS   Naba A, Clauser KR, Mani DR, Carr SA and Hynes RO.
  TITLE     Quantitative proteomic profiling of the extracellular matrix of
            pancreatic islets during the angiogenic switch and insulinoma
            progression
  JOURNAL   Sci Rep 7, 40495 (2017)
   PUBMED   28071719
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1619)
  AUTHORS   Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M,
            Hoodless PA, Jones SJ, Marra MA and Helgason CD.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   7  (bases 1 to 1619)
  AUTHORS   Lu J, Izvolsky KI, Qian J and Cardoso WV.
  TITLE     Identification of FGF10 targets in the embryonic lung epithelium
            during bud morphogenesis
  JOURNAL   J Biol Chem 280 (6), 4834-4841 (2005)
   PUBMED   15556938
REFERENCE   8  (bases 1 to 1619)
  AUTHORS   Seedorf H, Springer IN, Grundner-Culemann E, Albers HK, Reis A,
            Fuchs H, Hrabe de Angelis M and Acil Y.
  TITLE     Amelogenesis imperfecta in a new animal model--a mutation in
            chromosome 5 (human 4q21)
  JOURNAL   J Dent Res 83 (8), 608-612 (2004)
   PUBMED   15271968
REFERENCE   9  (bases 1 to 1619)
  AUTHORS   Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H
            and Herrmann BG.
  TITLE     Large-scale screen for genes controlling mammalian embryogenesis,
            using high-throughput gene expression analysis in mouse embryos
  JOURNAL   Mech Dev 98 (1-2), 77-94 (2000)
   PUBMED   11044609
REFERENCE   10 (bases 1 to 1619)
  AUTHORS   Fernandez MP, Copeland NG, Gilbert DJ, Jenkins NA and Morgan RO.
  TITLE     Mouse annexin III cDNA, genetic mapping and evolution
  JOURNAL   Gene 207 (1), 43-51 (1998)
   PUBMED   9511742
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK150922.1 and AJ001633.1.
            
            [WARNING] On Apr 25, 2023 this sequence was replaced by
            NM_013470.3.
            
            On Nov 20, 2007 this sequence version replaced NM_013470.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ001633.1, BC090634.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1322              AK150922.1         2-1323
            1323-1619           AJ001633.1         1306-1602
FEATURES             Location/Qualifiers
     source          1..1619
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 47.29 cM"
     gene            1..1619
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /note="annexin A3"
                     /db_xref="GeneID:11745"
                     /db_xref="MGI:MGI:1201378"
     exon            1..179
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            180..232
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     CDS             218..1189
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /EC_number="3.1.4.43"
                     /note="PAP-III; annexin-3; lipocortin III; 35-alpha
                     calcimedin; placental anticoagulant protein III; annexin
                     III"
                     /codon_start=1
                     /product="annexin A3"
                     /protein_id="NP_038498.2"
                     /db_xref="CCDS:CCDS51568.1"
                     /db_xref="GeneID:11745"
                     /db_xref="MGI:MGI:1201378"
                     /translation="MASIWVGPRGTIKDYPGFSPSVDAEAIRKAIRGLGTDEKTLINI
                     LTERSNAQRQLIVKQYQAAYEQELKDDLKGDLSGHFEHVMVALVTAPALFDAKQLKKS
                     MKGTGTDEDALIEILTTRSSRQMKEISQAYYTVYKKSLGDDISSETSGDFRKALLTLA
                     DGRRDESLKVDEHLAKKDAQILYNAGENKWGTDEDKFTEVLCLRSFPQLKLTFDEYRN
                     ISQKDIEDSIKGELSGHFEDLLLAIVHCARNTPAFLAERLHQALKGAGTDEFTLNRIM
                     VSRSEIDLLDIRHEFKKHYGYSLYSAIQSDTSGDYRTVLLKICGEDD"
     exon            233..320
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            321..415
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            416..529
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            530..620
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            621..700
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            701..757
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            758..851
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            852..947
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1006
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1129
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1597
                     /gene="Anxa3"
                     /gene_synonym="Anx3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggatccaaga gccacttgca agccggtcct gggcagtccg tgagtagaaa caggaggagg
       61 ggctgaggaa gggtgcggtc tgggttgcca cccaggctag ccgggagcta cggccggccg
      121 aggctgatct ttcaccttcg ctgagcttct gcctgggctt cgcctccgcg gccccaagga
      181 ttgctgtgat ctcggcttga gagaaaggtg gactgtcatg gcctctatct gggttggacc
      241 tcgaggaacc ataaaagatt atccaggctt tagcccgtcg gtggatgccg aagctatccg
      301 gaaagcgatc agaggacttg ggactgacga gaaaaccctc atcaacattc tgacggagcg
      361 gtcgaacgcg cagcgacagc tgattgtcaa gcagtaccaa gcagcgtatg aacaggagct
      421 gaaagatgac ttgaagggtg atctctctgg ccacttcgag cacgtcatgg tggctcttgt
      481 tactgcacca gccctgtttg atgcgaagca actgaagaaa tccatgaagg gaactggcac
      541 agatgaagat gccctgattg aaatcctaac aaccaggtca agcaggcaga tgaaggaaat
      601 ctcgcaggcc tattatacag tgtataagaa gagcctcggg gatgacatta gctctgagac
      661 gtctggagac ttccggaaag ctctgctgac tctggcagat ggtagaagag atgaaagcct
      721 caaagtggat gaacatctgg ccaaaaagga tgctcagatc ctctataatg ctggtgagaa
      781 caaatggggc acagacgaag acaaattcac cgaggtcttg tgtctacgga gcttcccgca
      841 gctgaaacta acatttgatg agtacagaaa tattagccag aaggacattg aggacagcat
      901 taaaggagaa ttatctggac attttgaaga cctgctgctg gccatagttc attgtgcgag
      961 gaacactcca gcgtttttgg cagaaagact tcatcaggct ttgaagggtg ctggaacaga
     1021 tgaattcact ctgaacagaa taatggtttc cagatcagag attgatcttt tggacatcag
     1081 acatgagttc aagaagcact atggctactc tctatactcg gccatccaat cagatacttc
     1141 tggagactac agaaccgtgc tcttgaagat ctgtggagaa gatgattgaa gaagatggct
     1201 cccaatggct gcctgccctg atggtggacc gcctcaaaat ctctgcacac tgctttcatg
     1261 cagcactcta aagtgcaagc aaatgcaaga cagaacctgt ctgcctgata ggcattggca
     1321 tcgttcagtg caatggcaaa aatgaacttg attttatttc agaccatctc attcatgata
     1381 agggaaattc aatctagaat taaagaccta ctaatgattt tctgtttggc ttaggaagtt
     1441 ggaatctgtg tagttcaaaa ccattaaaca taaatcagga tactaaagat ggctgccttt
     1501 cctaattgta atttgtgtat ttgttttcag tatctactaa tactgtatgt tgcctggtgc
     1561 caacaaatat ttcaaaatac atttgttgta aatgctcaaa aaaaaaaaaa aaaaaaaaa
//
