LOCUS       NM_027211               1408 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus annexin A13 (Anxa13), mRNA.
ACCESSION   NM_027211
VERSION     NM_027211.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1408)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1408)
  AUTHORS   McCulloch,K.M., Yamakawa,I., Shifrin,D.A. Jr., McConnell,R.E.,
            Foegeding,N.J., Singh,P.K., Mao,S., Tyska,M.J. and Iverson,T.M.
  TITLE     An alternative N-terminal fold of the intestine-specific annexin
            A13a induces dimerization and regulates membrane-binding
  JOURNAL   J Biol Chem 294 (10), 3454-3463 (2019)
   PUBMED   30610115
  REMARK    GeneRIF: a mechanism for how the association of the ANX A13a
            isoform with the membrane is regulated
REFERENCE   3  (bases 1 to 1408)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   4  (bases 1 to 1408)
  AUTHORS   Iglesias,J.M., Morgan,R.O., Jenkins,N.A., Copeland,N.G.,
            Gilbert,D.J. and Fernandez,M.P.
  TITLE     Comparative genetics and evolution of annexin A13 as the founder
            gene of vertebrate annexins
  JOURNAL   Mol Biol Evol 19 (5), 608-618 (2002)
   PUBMED   11961095
  REMARK    GeneRIF: Mouse annexin A13 cDNA was used to map the gene to an
            orthologous linkage group in mouse chromosome 15 (between Sdc2 and
            Myc by backcross analysis).
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ306451.1, BB617542.1 and AV289596.2.
            
            On Oct 20, 2007 this sequence version replaced NM_027211.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ306451.1, BC013521.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                AJ306451.1         1-52
            53-518              BB617542.1         50-515
            519-1216            AJ306451.1         519-1216
            1217-1403           AV289596.2         471-657
            1404-1408           AJ306451.1         1404-1408
FEATURES             Location/Qualifiers
     source          1..1408
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 24.66 cM"
     gene            1..1408
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /note="annexin A13"
                     /db_xref="GeneID:69787"
                     /db_xref="MGI:MGI:1917037"
     exon            1..59
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..998
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /note="annexin-13; annexin XIII"
                     /codon_start=1
                     /product="annexin A13"
                     /protein_id="NP_081487.1"
                     /db_xref="GeneID:69787"
                     /db_xref="MGI:MGI:1917037"
                     /translation="MGNRHAKERSHHHGFDADRDAKKLYKACKGMGTDEAAIIEVLSS
                     RTSEERQQIKQKYKEKYGKDLEEVLNSELSGNFKKTALALLDRPNEYAARQLQKAMKG
                     VGTDEAMLIEILCTRSNKEIVAIKEAYQRLFGRSLESDVKEDTSGNLRKILVSLLQAS
                     RDEEDTVDKELAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIG
                     KDMEETIEEETSGDLKKAYLTIVRCAQDLEGYFADLLYKAMKGMGTDEETLIRIIVTR
                     AEVDLQGIKAKFQEKYQKSLSDMVHSDTSGDFRKLLVALLH"
     exon            60..138
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            139..233
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            234..404
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            405..438
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            439..518
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            519..587
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            588..689
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            690..765
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            766..878
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            879..1408
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1298..1303
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1318
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /note="major polyA site"
     regulatory      1382..1387
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1402
                     /gene="Anxa13"
                     /gene_synonym="1810034H17Rik"
                     /note="major polyA site"
ORIGIN      
        1 ctcttcttga agaaacccag ggcagtcatc ccagagaaga ggaaatgggg aatcgtcatg
       61 ccaaagagag aagccatcac cacggctttg atgcagaccg agatgccaaa aagctgtaca
      121 aagcctgcaa aggaatggga acggatgaag cagccatcat tgaagtctta tccagcagga
      181 catcggagga gaggcaacag ataaagcaga agtacaagga gaagtatggc aaggacttag
      241 aggaggtgct taacagtgaa ctgagtggaa acttcaagaa gacagctttg gcccttctgg
      301 atcggcccaa tgagtacgcc gcacggcagc tgcagaaagc tatgaagggc gtaggcaccg
      361 acgaggccat gctcatagag atcctatgca cacgaagcaa caaggaaatt gtcgccatca
      421 aagaagctta ccaaaggcta tttggcagga gccttgaatc tgatgtcaaa gaagacacaa
      481 gtggaaacct gagaaagatt ctggtgtccc tgttacaggc cagtcgtgat gaagaagaca
      541 ctgtggacaa ggaattggct ggtcaggatg ccaaagattt gtatgatgca ggcgaaggtc
      601 gctggggcac tgacgaactt gccttcaatg aagtcctggc caagaggagc tacaagcagt
      661 tgcgcgccac ctttcaagct tatcagattc tcattggcaa agacatggaa gaaaccattg
      721 aagaagagac atcgggagac ttgaagaagg cctatttaac tatagtgaga tgtgcccagg
      781 accttgaggg ctattttgct gacctactat acaaggccat gaagggtatg gggacagatg
      841 aggagacatt aattcgcatc attgtgacca gagcagaggt ggacctgcag gggataaagg
      901 ccaagttcca ggagaagtat cagaagtctc tctctgacat ggttcactca gatacctctg
      961 gggacttccg gaaactgctg gtagctctct tgcactgatc caagcctgag gagaaacccc
     1021 catagcagga ttcttcctcg gaacaaatca aatttggaaa tgggtgaaaa cccttcaccc
     1081 cctggattgt ttattcatgg atttaaaagg agccccaagg ctaaattgtc gaagtcggga
     1141 gcagcctcct ccaagggctt gaacagttca ccttgaatgc tggcttagca ggaacctgaa
     1201 ctgcctgcct tccagtctcc ctttagcatt tgaagcgaat gctttctaag cacaaatgga
     1261 atcagcagtt ggtgggggga agaacccgaa catttataat aaaatgttta gaaaattata
     1321 tgcctcccag atgtacagag ccaaagcaga ggttaaatgg ctaatgcggc gtaaagacaa
     1381 gattaaacgg tttgctcatt tccccttc
//
