LOCUS       NM_013469               2413 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus annexin A11 (Anxa11), mRNA.
ACCESSION   NM_013469 NR_164330 NR_164331 XM_006519756 XM_908206
VERSION     NM_013469.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2413)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2413)
  AUTHORS   Naba,A., Clauser,K.R., Mani,D.R., Carr,S.A. and Hynes,R.O.
  TITLE     Quantitative proteomic profiling of the extracellular matrix of
            pancreatic islets during the angiogenic switch and insulinoma
            progression
  JOURNAL   Sci Rep 7, 40495 (2017)
   PUBMED   28071719
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2413)
  AUTHORS   Liu,S., Guo,C., Wang,J., Wang,B., Qi,H. and Sun,M.Z.
  TITLE     ANXA11 regulates the tumorigenesis, lymph node metastasis and
            5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by
            targeting c-Jun
  JOURNAL   Oncotarget 7 (13), 16297-16310 (2016)
   PUBMED   26908448
  REMARK    GeneRIF: ANXA11 level regulates lymph node metastases and 5-FU
            resistance of Hca-P murine hepatocarcinoma cells via c-Jun pathway
REFERENCE   4  (bases 1 to 2413)
  AUTHORS   Liu,S., Wang,J., Guo,C., Qi,H. and Sun,M.Z.
  TITLE     Annexin A11 knockdown inhibits in vitro proliferation and enhances
            survival of Hca-F cell via Akt2/FoxO1 pathway and MMP-9 expression
  JOURNAL   Biomed Pharmacother 70, 58-63 (2015)
   PUBMED   25776480
  REMARK    GeneRIF: This study showed that Annexin A11 knockdown inhibits the
            in vitro proliferation and cell apoptosis of Hca-F cell via
            Akt2/FoxO1 and/or MMP-9 expression pathway.
REFERENCE   5  (bases 1 to 2413)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   6  (bases 1 to 2413)
  AUTHORS   Bances,P., Fernandez,M.R., Rodriguez-Garcia,M.I., Morgan,R.O. and
            Fernandez,M.P.
  TITLE     Annexin A11 (ANXA11) gene structure as the progenitor of paralogous
            annexins and source of orthologous cDNA isoforms
  JOURNAL   Genomics 69 (1), 95-103 (2000)
   PUBMED   11013079
REFERENCE   7  (bases 1 to 2413)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   8  (bases 1 to 2413)
  AUTHORS   Downes,G.B., Gilbert,D.J., Copeland,N.G., Gautam,N. and
            Jenkins,N.A.
  TITLE     Chromosomal mapping of five mouse G protein gamma subunits
  JOURNAL   Genomics 57 (1), 173-176 (1999)
   PUBMED   10191100
REFERENCE   9  (bases 1 to 2413)
  AUTHORS   Fernandez,M.P., Copeland,N.G., Gilbert,D.J., Jenkins,N.A. and
            Morgan,R.O.
  TITLE     The genetic origin of mouse annexin VIII
  JOURNAL   Mamm Genome 9 (1), 8-14 (1998)
   PUBMED   9434938
REFERENCE   10 (bases 1 to 2413)
  AUTHORS   Fernandez,M.P., Jenkins,N.A., Gilbert,D.J., Copeland,N.G. and
            Morgan,R.O.
  TITLE     Sequence and chromosomal localization of mouse annexin XI
  JOURNAL   Genomics 37 (3), 366-374 (1996)
   PUBMED   8938449
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY723474.1, AK140375.1, AK137158.1 and BQ174399.1.
            
            On or before Oct 28, 2020 this sequence version replaced
            NR_164330.1, NR_164331.1, NM_013469.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC012875.1, U65986.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                BY723474.1         2-29
            29-1783             AK140375.1         2-1756
            1784-1924           AK140375.1         1758-1898
            1925-2388           AK137158.1         2235-2698
            2389-2413           BQ174399.1         1-25                c
FEATURES             Location/Qualifiers
     source          1..2413
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 15.06 cM"
     gene            1..2413
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /note="annexin A11"
                     /db_xref="GeneID:11744"
                     /db_xref="MGI:MGI:108481"
     exon            1..141
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            142..204
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..1661
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /note="CAP-50; annexin-11; calcyclin-associated annexin
                     50; annexin XI; Annexin A11 (Annexin XI)
                     (Calcyclin-associated annexin 50) (CAP-50)"
                     /codon_start=1
                     /product="annexin A11"
                     /protein_id="NP_038497.2"
                     /db_xref="CCDS:CCDS26875.1"
                     /db_xref="GeneID:11744"
                     /db_xref="MGI:MGI:108481"
                     /translation="MSYPGYPPPAGGYPPAAPGGGPWGGAGYPPPSMPPIGLDNVANY
                     AGQFNQDYLSGMAANMSGTFGGANVPNLYPGAPGGGYPPVPPGGFGQPPPAQQPVPPY
                     GMYPPPGGNPPPGMPSYPAYPGAPVPGQPMPPTGQQPPGAYPGQPPMTYPGQSPMPPP
                     GQQPVPSYPGYSGSSTITPAVPPAQFGNRGTITAASGFDPLRDAEVLRKAMKGFGTDE
                     QAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDV
                     YEIKEAIKGAGTDEACLIEIFASRSNEHIRELSRAYKTEFQKTLEEAIRSDTSGHFQR
                     LLISLSQGNRDESTNVDMSLVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAV
                     FNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDR
                     TLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTSGDYRKILLKICGGND"
     exon            205..317
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            318..704
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            705..792
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            793..887
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1001
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1092
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1172
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1229
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1323
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1419
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1478
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1601
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
     exon            1602..2395
                     /gene="Anxa11"
                     /gene_synonym="100039484; 100039503; A830099O17Rik; Anx11;
                     Gm2260; Gm2274"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaacgcggcc gcgcccggag agttttccgc cttgccggct cctccttcga ccgtgcgcag
       61 acactctcgg gttaggatcc aggaaagcgg gagtaggaag gagttgctat ccgagctcag
      121 tgtcccggtc cctggtgcca gctctagcca tgagctaccc aggctaccct ccacctgccg
      181 gtggctaccc tccagctgca ccaggtggtg gtccctgggg aggtgctggc taccctcctc
      241 ccagcatgcc ccctatcggg ctggataacg tagccaacta tgcggggcag ttcaaccagg
      301 actacctctc aggcatggca gccaacatgt ctggaacatt tggaggagcc aacgtgccaa
      361 atctgtatcc tggggctcct gggggtggct atcctccagt ccctcctggt ggctttgggc
      421 agccccctcc tgcccagcag cctgtccctc cttatggaat gtatccgccc ccaggaggaa
      481 acccacctcc tgggatgcct tcatatccag cctacccagg ggcccctgtg ccaggccagc
      541 ctatgccacc cactgggcag cagcccccag gggcctatcc tgggcagcct ccaatgacct
      601 atcctgggca gtcaccaatg ccaccccctg ggcagcagcc agtgccaagt tacccaggat
      661 actcgggatc tagtaccatc acccctgctg tgccaccagc ccagtttgga aaccgaggta
      721 ccatcactgc tgcttctgga tttgacccct tgcgagatgc cgaggtcctg cgcaaggcta
      781 tgaagggctt tggaacggat gagcaggcca tcatcgactg cctggggagc cggtccaaca
      841 agcagcgtca gcagatcctc ctatccttca agacggccta tggcaaggat ttgatcaaag
      901 acctaaaatc agaactgtcg ggaaactttg agaagactat cctggccctg atgaagaccc
      961 cggtcctgtt tgatgtctat gagataaagg aagctatcaa gggggctggt actgatgagg
     1021 cctgcctgat tgagatcttc gcttccagaa gtaacgaaca catccgggag ctaagcaggg
     1081 cctacaaaac agagttccaa aaaactctgg aggaggccat tcgaagcgac acatcaggac
     1141 acttccagcg gctcctcatc tctctctctc agggaaaccg tgatgagagc acaaatgtgg
     1201 acatgtccct tgtccagaga gatgtccagg agctgtatgc agctggggag aaccgcctgg
     1261 gaacagacga gtccaagttc aacgccatcc tgtgctcccg gagccgggcc cacctggtgg
     1321 cagttttcaa cgagtatcag aggatgacgg gccgagacat tgagaagagc atctgccggg
     1381 agatgtctgg ggacctggag cagggcatgc tggctgtggt gaaatgcctc aagaacaccc
     1441 ccgccttctt tgctgaaagg ctcaacaagg ctatgagggg agcaggaaca aaggaccgga
     1501 ccctgattcg catcatggtg tctcgcagcg agcttgacct gctggatatc cgagcagagt
     1561 ataagcggat gtacggcaag tcactgtacc acgatatcac gggagatact tctggagact
     1621 atcgaaagat tctactgaag atctgtggtg gcaacgactg agctgtggca gtggctcacc
     1681 tgtgccccct gctggcattg gccaggaaac gtcccaaaga gcacacttcg gtttccctat
     1741 ctaataaccc caaattaccg ccgccgtctc cccccccccc cccacgcaag gccatggcct
     1801 ttcccttctg gtcccccctc atccacatat tgtgccgaaa gggcccagga gggctggggt
     1861 tctcaggggg catctccctg gccctcatag cctcttgctg gcagatcaga tgtttatctc
     1921 tccggttcct gcactcactc cttgttgctt gtggctaaga ctcttagctt cgtggtagac
     1981 atgcgatttt gtatttttat ttgaaaatgt tttttaaacc atcgttgcca gtcagatgca
     2041 tacgagcgta tttactgtat cgtgtttgtg ggaggagtga tgggtgagag gggctcccca
     2101 tccttgccta ggacttttta aaagggaggc cttgtgacgg tactgtggtg tctggtgaaa
     2161 atgtgtcatg aggtttgttt ttgccaaact cactcctttt tagaaaaaag ggcagaaaat
     2221 catttgttcc atttttccat gcaaaaccat gcaagaatta aagccacccc cccacccccc
     2281 ccccgccaat gacaaggctc cttgtagttt gtaatgtgcc ttaaacctga atgtctgtag
     2341 ccaaaagctg tttccaaata aaagtcagcc agttctggaa cattctggaa atgtcaaaaa
     2401 aaaaaaaaaa aaa
//
