LOCUS       NM_023210               3273 bp    mRNA    linear   ROD 26-JUN-2024
DEFINITION  Mus musculus acidic nuclear phosphoprotein 32 family member E
            (Anp32e), transcript variant 1, mRNA.
ACCESSION   NM_023210
VERSION     NM_023210.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3273)
  AUTHORS   Gopinathan,G., Xu,Q., Luan,X. and Diekwisch,T.G.H.
  TITLE     CFDP1 regulates the stability of pericentric heterochromatin
            thereby affecting RAN GTPase activity and mitotic spindle formation
  JOURNAL   PLoS Biol 22 (4), e3002574 (2024)
   PUBMED   38630655
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3273)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3273)
  AUTHORS   Wei,J., Shan,Y., Xiao,Z., Wen,L., Tao,Y., Fang,X., Luo,H., Tang,C.
            and Li,Y.
  TITLE     Anp32e promotes renal interstitial fibrosis by upregulating the
            expression of fibrosis-related proteins
  JOURNAL   Int J Biol Sci 18 (15), 5897-5912 (2022)
   PUBMED   36263179
  REMARK    GeneRIF: Anp32e promotes renal interstitial fibrosis by
            upregulating the expression of fibrosis-related proteins.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3273)
  AUTHORS   Chen,X., Xue,G., Zhao,J., Zhang,Y., Zhang,S., Wang,W., Li,Y.,
            Yuan,J., He,L., Chan,C.Y., Liu,Y., Chen,W., Zhao,Y., Hu,P., Sun,H.,
            Kwok,C.K. and Wang,H.
  TITLE     Lockd promotes myoblast proliferation and muscle regeneration via
            binding with DHX36 to facilitate 5' UTR rG4 unwinding and Anp32e
            translation
  JOURNAL   Cell Rep 39 (10), 110927 (2022)
   PUBMED   35675771
  REMARK    GeneRIF: Lockd promotes myoblast proliferation and muscle
            regeneration via binding with DHX36 to facilitate 5' UTR rG4
            unwinding and Anp32e translation.
REFERENCE   5  (bases 1 to 3273)
  AUTHORS   Stefanelli,G., Makowski,C.E., Brimble,M.A., Hall,M., Reda,A.,
            Creighton,S.D., Leonetti,A.M., McLean,T.A.B., Zakaria,J.M.,
            Baumbach,J., Greer,C.B., Davidoff,A.M., Walters,B.J., Murphy,P.J.
            and Zovkic,I.B.
  TITLE     The histone chaperone Anp32e regulates memory formation,
            transcription, and dendritic morphology by regulating steady-state
            H2A.Z binding in neurons
  JOURNAL   Cell Rep 36 (7), 109551 (2021)
   PUBMED   34407406
  REMARK    GeneRIF: The histone chaperone Anp32e regulates memory formation,
            transcription, and dendritic morphology by regulating steady-state
            H2A.Z binding in neurons.
REFERENCE   6  (bases 1 to 3273)
  AUTHORS   Matilla,A. and Radrizzani,M.
  TITLE     The Anp32 family of proteins containing leucine-rich repeats
  JOURNAL   Cerebellum 4 (1), 7-18 (2005)
   PUBMED   15895553
  REMARK    Review article
REFERENCE   7  (bases 1 to 3273)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 3273)
  AUTHORS   Radrizzani,M., Vila-Ortiz,G., Cafferata,E.G., Di Tella,M.C.,
            Gonzalez-Guerrico,A., Perandones,C., Pivetta,O.H., Carminatti,H.,
            Idoyaga Vargas,V.P. and Santa-Coloma,T.A.
  TITLE     Differential expression of CPD1 during postnatal development in the
            mouse cerebellum
  JOURNAL   Brain Res 907 (1-2), 162-174 (2001)
   PUBMED   11430900
REFERENCE   9  (bases 1 to 3273)
  AUTHORS   Matsubae,M., Kurihara,T., Tachibana,T., Imamoto,N. and Yoneda,Y.
  TITLE     Characterization of the nuclear transport of a novel leucine-rich
            acidic nuclear protein-like protein
  JOURNAL   FEBS Lett 468 (2-3), 171-175 (2000)
   PUBMED   10692581
REFERENCE   10 (bases 1 to 3273)
  AUTHORS   Radrizzani,M., Brocardo,M.G., Gonzalez Solveyra,C., Bianchini,M.,
            Reyes,G.B., Cafferata,E.G., Vila Ortiz,G. and Santa-Coloma,T.A.
  TITLE     Development of monoclonal oligobodies and chemically synthesized
            oligobodies
  JOURNAL   Medicina (B Aires) 60 Suppl 2, 55-60 (2000)
   PUBMED   11188933
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY254191.1, AK049647.1, AK159446.1 and AI613710.1.
            
            On Jul 23, 2009 this sequence version replaced NM_023210.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.223206.1, AK172146.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                BY254191.1         2-35
            35-934              AK049647.1         2-901
            935-2099            AK159446.1         902-2066
            2100-2848           AK049647.1         2067-2815
            2849-3255           AK159446.1         2816-3222
            3256-3273           AI613710.1         205-222
FEATURES             Location/Qualifiers
     source          1..3273
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.59 cM"
     gene            1..3273
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /note="acidic nuclear phosphoprotein 32 family member E"
                     /db_xref="GeneID:66471"
                     /db_xref="MGI:MGI:1913721"
     exon            1..394
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /inference="alignment:Splign:2.1.0"
     CDS             341..1123
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /note="isoform 1 is encoded by transcript variant 1;
                     cerebellar postnatal development protein 1; LANP-like
                     protein; acidic (leucine-rich) nuclear phosphoprotein 32
                     family, member E"
                     /codon_start=1
                     /product="acidic leucine-rich nuclear phosphoprotein 32
                     family member E isoform 1"
                     /protein_id="NP_075699.3"
                     /db_xref="CCDS:CCDS17626.1"
                     /db_xref="GeneID:66471"
                     /db_xref="MGI:MGI:1913721"
                     /translation="MEMKKKINMELKNRAPEEVTELVLDNCLCVNGEIEGLNDTFKEL
                     EFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKD
                     LSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEE
                     EDDDDEDGDEDEEDEDEDEAGPPEGYEEEEDDDEDEAGSEVGEGEEEVGLSYLMKDEI
                     QDEEDDDDYVDEGEEEEEEEEEGLRGEKRKRDAEDDGEEDDD"
     exon            395..544
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            545..667
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            668..839
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            840..997
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1052
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..3260
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1419..1424
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /note="hexamer: ATTAAA"
     polyA_site      1439
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /note="major polyA site"
     regulatory      3237..3242
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /note="hexamer: AATAAA"
     polyA_site      3260
                     /gene="Anp32e"
                     /gene_synonym="2810018A15Rik; CPD1; LANP-L; LANPL;
                     mLANP-L"
                     /note="major polyA site"
ORIGIN      
        1 agggggggtt ggcggtgccg tgtcatggag gctcagtctc gcagcagcca ttgaagggga
       61 aggaactgcg ggcgcgcgcg tgtctctctc cctcactctc tctgtgtgaa agtgtgtgcg
      121 tgcccgagtg tgcgcgcgcg ggtgtgtgga ctcggaggtg ggggcagccg agttagtccc
      181 aagtcgtcgg actccatttg ctattctttt ctttctctcc cacacccgtg tggtagtggg
      241 cgttcgtctt tgcgtctctt ttcattcatc tccagacctt tagaggtttt tttagggttg
      301 gggatagtgg ggagggcagg cgaggggaaa ggaggaggac atggagatga agaagaagat
      361 taacatggag ttgaagaaca gagccccgga ggaggtgaca gagttagtcc tcgataattg
      421 cttgtgtgtc aatggggaaa tcgaaggcct gaatgacacc tttaaggaac tggagtttct
      481 tagcatggcc aacgtggagt tgagttcctt ggcccggctt cccagcttga ataaactccg
      541 gaagttggaa cttagtgaca atataatttc tggaggcttg gaagtcctgg cagagaaatg
      601 tccaaatctt acctacctca atctgagtgg aaacaaaata aaagatctca gtacagtaga
      661 agcgctgcaa aatcttaaaa atttgaaaag tctcgacttg tttaactgtg agatcacaaa
      721 cctggaagat tatagagaaa gtatttttga actgctgcag cagatcacct acctggacgg
      781 attcgaccag gaggacaacg aagctcccga ctcggaggag gaggatgacg acgacgagga
      841 tggagatgaa gatgaggaag atgaggacga agatgaagct ggcccaccgg aaggctatga
      901 agaggaggaa gatgacgatg aggatgaagc tggctcagaa gtgggagagg gagaagagga
      961 ggtgggcctc tcatacttaa tgaaagacga aattcaggat gaagaggacg atgatgacta
     1021 cgttgatgaa ggggaggagg aggaagaaga ggaggaagag ggtcttcggg gagagaagag
     1081 aaagcgagat gctgaggatg acggggagga agacgacgat tagacctcca ggaccaggcc
     1141 acctgacact cctgggcgct ggagagcgat cacattgtct ttgtttcttt atgtatgata
     1201 gctgtcccag taggagatga tgtgtaactt tttataggaa aagtgtggtt ttactatttt
     1261 ggccttacca ttccggttaa gatttgctag tctgttaatc ataatgttct tagaaaagaa
     1321 ttctcattca tcttcccata gtgaaattct ctagcactgt atttagattc tggattttta
     1381 taattcatgc ttaatgtatt agacattttt agcccataat taaaacattg ttgcttttac
     1441 acaggtgtag tttggtgcat ttcattcata gtgttttaaa gttatttata aattaaccaa
     1501 ttacactcag ctgtaatatg aaatggcagt agtcttttga atgataaagc tggttttttt
     1561 gtttttggtt gatttagaga cgatccggct gtcattagct tgaaggcatt tttgggggtg
     1621 gggttagggt atctgaaggc tttcctatca tggtttggga agtagaagca gagcgagagg
     1681 gttctcttca gaggcaggtc atggactcag ttctgctcag tgacagttca gggcccttta
     1741 aggagcctgt ccctttctaa ggccagactt gccgtggagc ggtctctggg tggccgtgcc
     1801 agcaggctgt cggtcgggtc agctgtgtgt cccctcccag ctgctccaga aggttctgtc
     1861 accttcattg cttcattcct gttcccatcc aaaagaaagc tggcaaaagc tgtaatgccc
     1921 cagagacttc atctgcacct cagccatctg tctcggtttc aaacaagtgg catggaagag
     1981 atggagcatt caagttacag taccgagggc ttcgtgtcag aggcaggcgt tgctgacggc
     2041 ccgagtctgc taggataagc agcagcgtcc tctcgcagag gtcagactga ttgccagctg
     2101 agaactgatg agacgttcag ggctagtttc taagttttcc tagtgatttg gataccaact
     2161 ctgtgaagta tttattatgt ttctgagagc aacctttaat tcttcctgta gttttgaaag
     2221 cgtgatcagt tgtagccttt gattggaaca tagtggcaat aggagactgt ttgaaaatca
     2281 atcttgaagt gttggtattt atttcaaatg aatgtctgaa aaatagaaaa aacatttggg
     2341 gtacgggtat gtgttttctc gtggcttcaa acatgagcgg acaggcccct ctctctctct
     2401 ccctttgtcc cggaagctcc atgcacaagg cacttgcttt ttaagtcttg gttgccagtt
     2461 tttgttttcc ttttgtttta tatacttcag gtgggttttt gttttgtttt gtctttttct
     2521 ttctttttaa acttagcatc agcatacgta ttttgcctct cttctgggac acatcgaaat
     2581 tgcaacagtg gggctgctgc tctttcaact tcacatgtct gacctggttt ttaacatagc
     2641 aagtatgaac ttatttgtag agaagctaat aaaagttgca tgcctgactg agataaatgt
     2701 gtactgagtt cagcgcaagt gcagggatcg ccaaaggatt ggctttgttt ccttgtttca
     2761 gtaattggaa ctcctgctgt cagtctctaa agaattctct ttgcaaacta tgccaggttc
     2821 aaaataaatg cttattttta aaaatgaaat ctatatattg actttttatc aatcatctat
     2881 tgtgcaatca aaattagagt tcttgagttt aaaaacaacg catagggcct ccagataact
     2941 attaagactt atttagctta gtgggtggta ttttcatgca aataagcaag ggtgggtttt
     3001 ctattctgta gaagttctgg gttctgttct aaccctctct gtactgtgcg tgtgtatacc
     3061 atatgtgaag tccttagaga ctttgaggtt gattgatact tttgtgcagc tgtgctttga
     3121 ctaacgccat cacagtgtta aacacgagga cgggcagcgc tgatcatggg gttctgacta
     3181 ttttgttttt tttcccttac tgctgtaact taagtttttg aaactgcatt gctttgaata
     3241 aattgaagcg ttattaataa aaaaaaaaaa aaa
//
