LOCUS       NM_130889               1702 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus acidic nuclear phosphoprotein 32 family member B
            (Anp32b), mRNA.
ACCESSION   NM_130889 XM_975443
VERSION     NM_130889.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1702)
  AUTHORS   Tscherner,A.K., McClatchie,T., Macaulay,A.D. and Baltz,J.M.
  TITLE     Relationship of quantitative reverse transcription polymerase chain
            reaction (RT-PCR) to RNA Sequencing (RNAseq) transcriptome
            identifies mouse preimplantation embryo reference genesdagger
  JOURNAL   Biol Reprod 109 (5), 601-617 (2023)
   PUBMED   37669129
REFERENCE   2  (bases 1 to 1702)
  AUTHORS   Yang,Q., Liu,H.R., Yang,S., Wei,Y.S., Zhu,X.N., Zhi,Z., Zhu,D.,
            Chen,G.Q. and Yu,Y.
  TITLE     ANP32B suppresses B-cell acute lymphoblastic leukemia through
            activation of PU.1 in mice
  JOURNAL   Cancer Sci 114 (7), 2882-2894 (2023)
   PUBMED   37137487
  REMARK    GeneRIF: ANP32B suppresses B-cell acute lymphoblastic leukemia
            through activation of PU.1 in mice.
REFERENCE   3  (bases 1 to 1702)
  AUTHORS   Peacock,T.P., Sheppard,C.M., Lister,M.G., Staller,E., Frise,R.,
            Swann,O.C., Goldhill,D.H., Long,J.S. and Barclay,W.S.
  TITLE     Mammalian ANP32A and ANP32B Proteins Drive Differential Polymerase
            Adaptations in Avian Influenza Virus
  JOURNAL   J Virol 97 (5), e0021323 (2023)
   PUBMED   37074204
  REMARK    GeneRIF: Mammalian ANP32A and ANP32B Proteins Drive Differential
            Polymerase Adaptations in Avian Influenza Virus.
REFERENCE   4  (bases 1 to 1702)
  AUTHORS   Yang,S., Zhu,X.N., Zhang,H.L., Yang,Q., Wei,Y.S., Zhu,D., Liu,M.D.,
            Shen,S.M., Xia,L., He,P., Ge,M.K., Pan,Y.L., Zhao,M., Wu,Y.L.,
            Zheng,J.K., Chen,G.Q. and Yu,Y.
  TITLE     ANP32B-mediated repression of p53 contributes to maintenance of
            normal and CML stem cells
  JOURNAL   Blood 138 (24), 2485-2498 (2021)
   PUBMED   34359074
  REMARK    GeneRIF: ANP32B-mediated repression of p53 contributes to
            maintenance of normal and CML stem cells.
REFERENCE   5  (bases 1 to 1702)
  AUTHORS   Beck,S., Zickler,M., Pinho Dos Reis,V., Gunther,T., Grundhoff,A.,
            Reilly,P.T., Mak,T.W., Stanelle-Bertram,S. and Gabriel,G.
  TITLE     ANP32B Deficiency Protects Mice From Lethal Influenza A Virus
            Challenge by Dampening the Host Immune Response
  JOURNAL   Front Immunol 11, 450 (2020)
   PUBMED   32231671
  REMARK    GeneRIF: ANP32B Deficiency Protects Mice From Lethal Influenza A
            Virus Challenge by Dampening the Host Immune Response.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1702)
  AUTHORS   Reilly,P.T., Afzal,S., Gorrini,C., Lui,K., Bukhman,Y.V.,
            Wakeham,A., Haight,J., Ling,T.W., Cheung,C.C., Elia,A.J.,
            Turner,P.V. and Mak,T.W.
  TITLE     Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse
            reveals a hierarchy of ANP32 importance in mammalian development
  JOURNAL   Proc Natl Acad Sci U S A 108 (25), 10243-10248 (2011)
   PUBMED   21636789
  REMARK    GeneRIF: Data demonstrate a hierarchy of importance for the
            mammalian Anp32 genes, with Anp32b being the most critical for
            normal development.
REFERENCE   7  (bases 1 to 1702)
  AUTHORS   Matilla,A. and Radrizzani,M.
  TITLE     The Anp32 family of proteins containing leucine-rich repeats
  JOURNAL   Cerebellum 4 (1), 7-18 (2005)
   PUBMED   15895553
  REMARK    Review article
REFERENCE   8  (bases 1 to 1702)
  AUTHORS   Planelles,L., Carvalho-Pinto,C.E., Hardenberg,G., Smaniotto,S.,
            Savino,W., Gomez-Caro,R., Alvarez-Mon,M., de Jong,J., Eldering,E.,
            Martinez-A,C., Medema,J.P. and Hahne,M.
  TITLE     APRIL promotes B-1 cell-associated neoplasm
  JOURNAL   Cancer Cell 6 (4), 399-408 (2004)
   PUBMED   15488762
REFERENCE   9  (bases 1 to 1702)
  AUTHORS   Amasaki,H., Ogawa,M., Nagasao,J., Mutoh,K., Ichihara,N., Asari,M.
            and Shiota,K.
  TITLE     Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in
            developing murine palatal rugae
  JOURNAL   Ann Anat 185 (6), 517-523 (2003)
   PUBMED   14703996
REFERENCE   10 (bases 1 to 1702)
  AUTHORS   Sun,W., Hattori,N., Mutai,H., Toyoshima,Y., Kimura,H., Tanaka,S.
            and Shiota,K.
  TITLE     PAL31, a nuclear protein required for progression to the S phase
  JOURNAL   Biochem Biophys Res Commun 280 (4), 1048-1054 (2001)
   PUBMED   11162633
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ053476.1, AK165807.1 and CK623910.1.
            
            On Sep 13, 2016 this sequence version replaced NM_130889.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK165807.1, BC003489.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-121               CJ053476.1         13-133
            122-1557            AK165807.1         1-1436
            1558-1702           CK623910.1         487-631
FEATURES             Location/Qualifiers
     source          1..1702
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 24.79 cM"
     gene            1..1702
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /note="acidic nuclear phosphoprotein 32 family member B"
                     /db_xref="GeneID:67628"
                     /db_xref="MGI:MGI:1914878"
     exon            1..424
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /inference="alignment:Splign:2.1.0"
     CDS             371..1189
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /note="acidic protein rich in leucines; proliferation
                     related acidic leucine rich protein PAL31; acidic
                     (leucine-rich) nuclear phosphoprotein 32 family, member B"
                     /codon_start=1
                     /product="acidic leucine-rich nuclear phosphoprotein 32
                     family member B"
                     /protein_id="NP_570959.1"
                     /db_xref="CCDS:CCDS18151.1"
                     /db_xref="GeneID:67628"
                     /db_xref="MGI:MGI:1914878"
                     /translation="MDMKRRIHLELRNRTPAAVRELVLDNCKAMDGKIEGLTDEFVNL
                     EFLSLISVGLFSVSDLPKLPKLKKLELSENRIFGGLDRLAEELPSLTHLNLSGNNLKD
                     ISTLEPLKRLDCLKSLDLFGCEVTNRSDYRETVFRLLPQLSYLDGYDREDQEAPDSDV
                     EVDSVEEAPDSDGEVDGVDKEEEDEEGEDEEEEEDEDGEEEEDEDEEDEDEDEDVEGE
                     DDEDEVSGEEEEFGHDGEVDEDEEDEDEDEDEEEEESGKGEKRKRETDDEGEDD"
     exon            425..574
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /inference="alignment:Splign:2.1.0"
     exon            575..697
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /inference="alignment:Splign:2.1.0"
     exon            698..926
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1051
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1121
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1692
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1668..1673
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /note="hexamer: AATAAA"
     polyA_site      1692
                     /gene="Anp32b"
                     /gene_synonym="2410015B15Rik; PAL31; PHAPI2a; Ssp29"
                     /note="major polyA site"
ORIGIN      
        1 gcctcccaag tccgcgctgc agcccgggct cccgagccga gcggcgccgc gcagggccga
       61 gtggagccga gcagccgccg cgtcgcgtcg ccggtttaag cgcagtgcgg ggccttggcc
      121 gggggcggcg gtagtgaggc cagagccgcg ctccagcccc cttttccctc catggtttct
      181 ctccgctccc gcgagtaact tggctccggg ggctccgctc gcccgcacgc ccgcacgccg
      241 cccggggacc acgccgccgc ctcctccagc cgcctccctc cgacggccct cgccgcgcag
      301 gccgggtcgc ctctcccccc tccgcccccg ccgcggaaag ttaagtttgg agagggggga
      361 cgaggggaac atggatatga agaggaggat ccacctggag ctgaggaacc ggaccccggc
      421 agccgttcga gaacttgtct tggacaattg caaagcaatg gatggaaaaa ttgaggggtt
      481 aacagatgaa tttgtgaact tagagttcct cagtttaata agtgtaggct tgttttcagt
      541 ttcagacctc ccgaagctac ctaagttgaa aaagcttgag ctcagtgaaa atagaatctt
      601 cggaggtctg gacagactag cagaagaact tccaagcctc acacatctga acctaagtgg
      661 caataacctg aaagatatca gcaccttgga gccgttgaaa aggttggatt gtctgaaaag
      721 cctggatctg tttggctgtg aggtcactaa ccggagtgat taccgagaaa ctgtcttcag
      781 gctcctgccc cagctgtcct atctggatgg ctatgaccga gaggaccagg aagcacctga
      841 ctcagatgtg gaggtggata gtgtagagga agcccccgac tcagatggag aggtggatgg
      901 tgtggacaaa gaggaagagg atgaagaagg agaggatgaa gaggaagagg aagatgagga
      961 tggtgaggaa gaagaagatg aagacgaaga agatgaggat gaagatgagg atgtagaagg
     1021 agaagatgat gaggatgaag tcagcgggga ggaagaagaa tttggacatg atggggaagt
     1081 tgatgaagat gaagaagatg aggatgaaga tgaggatgaa gaggaggaag aaagtgggaa
     1141 gggtgaaaag agaaagagag aaacagatga cgaaggagaa gatgattaag acccgaaaca
     1201 acctgcaaga aacagaactg ttgagtattg gttggactgc tcatggattt ggtagctgtt
     1261 ttaaaaaggt agctgtgata caagccccag gacaccccca cccaaagagc caaagaatag
     1321 ttcccgcgac attccgcctt cctccgttag ccccttggta atccaccacc aagcctgggg
     1381 acttcgcccc aacaaaattg taaacgttgt taggttttcg tgtaagactc ttgctgtatc
     1441 gtgacagctg tgattggtga gttgaccgtc ctggctgcca gttacactgc gattgtaaca
     1501 acatttttac tttctgtaca acaaggaaaa gctttgtaaa taaaatctta acattttggg
     1561 tctgttttct catgcttttc tttctttttt tttttctttc tttttttaaa gatattagga
     1621 cattttgtgt gataactgcc aaaaccgtat tttctaagac taagcaaaat aaatgcatta
     1681 ctctttggta aaaaaaaaaa aa
//
