LOCUS       NM_027303               1000 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus ankyrin repeat domain 60 (Ankrd60), transcript variant
            1, mRNA.
ACCESSION   NM_027303 XM_130735
VERSION     NM_027303.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Barrick D, Ferreiro DU and Komives EA.
  TITLE     Folding landscapes of ankyrin repeat proteins: experiments meet
            theory
  JOURNAL   Curr Opin Struct Biol 18 (1), 27-34 (2008)
   PUBMED   18243686
  REMARK    Review article
REFERENCE   2  (bases 1 to 1000)
  AUTHORS   Li J, Mahajan A and Tsai MD.
  TITLE     Ankyrin repeat: a unique motif mediating protein-protein
            interactions
  JOURNAL   Biochemistry 45 (51), 15168-15178 (2006)
   PUBMED   17176038
  REMARK    Review article
REFERENCE   3  (bases 1 to 1000)
  AUTHORS   Mosavi LK, Cammett TJ, Desrosiers DC and Peng ZY.
  TITLE     The ankyrin repeat as molecular architecture for protein
            recognition
  JOURNAL   Protein Sci 13 (6), 1435-1448 (2004)
   PUBMED   15152081
  REMARK    Review article
REFERENCE   4  (bases 1 to 1000)
  AUTHORS   Sedgwick SG and Smerdon SJ.
  TITLE     The ankyrin repeat: a diversity of interactions on a common
            structural framework
  JOURNAL   Trends Biochem Sci 24 (8), 311-316 (1999)
   PUBMED   10431175
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL807384.5.
            
            On Jun 24, 2019 this sequence version replaced NM_027303.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            CCDS Note: The coding region has been updated to start at a
            downstream in-frame start codon that is supported by conservation
            data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA466098.1, CN839684.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-284               AL807384.5         200099-200382       c
            285-415             AL807384.5         194601-194731       c
            416-581             AL807384.5         193154-193319       c
            582-1000            AL807384.5         190767-191185       c
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 97.04 cM"
     gene            1..1000
                     /gene="Ankrd60"
                     /gene_synonym="1700019A24Rik; 1700030G11Rik"
                     /note="ankyrin repeat domain 60"
                     /db_xref="GeneID:70065"
                     /db_xref="MGI:MGI:1917315"
     exon            1..284
                     /gene="Ankrd60"
                     /gene_synonym="1700019A24Rik; 1700030G11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             200..889
                     /gene="Ankrd60"
                     /gene_synonym="1700019A24Rik; 1700030G11Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 60
                     isoform 1"
                     /protein_id="NP_081579.2"
                     /db_xref="CCDS:CCDS50815.1"
                     /db_xref="GeneID:70065"
                     /db_xref="MGI:MGI:1917315"
                     /translation="MTVRELKEELDLMVGIPFNLQRLHFLDRGILMDDATLKFYDVIP
                     GALISLCIWHYDGWTELVLAAVEGDPSKMSCLGISEDTFYRTANSQHFKGEQWRQWTA
                     QRAFVALYISAHRGHVDAVQYLLGLGANCLAKSPLGRTPLHVVAAMGRTDCVQPLLEH
                     GASIHDRDLKSDTPITIARRLKRGHLEHKMFLLYWMVKSGSRDPDLVGRKALEKSSPG
                     MATRRSTILIS"
     exon            285..415
                     /gene="Ankrd60"
                     /gene_synonym="1700019A24Rik; 1700030G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            416..581
                     /gene="Ankrd60"
                     /gene_synonym="1700019A24Rik; 1700030G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            582..1000
                     /gene="Ankrd60"
                     /gene_synonym="1700019A24Rik; 1700030G11Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaacggcag ggggacgacc ccaaggcggg cgcgcgccac actcagccct ccagcagggc
       61 ccgcgcacag gttagggggc acacagggga cccgcttgcc tccaccgtgt cgccagactt
      121 gactcctgac gtctatgtcc tgcgggtgaa gctggaggag actggggagc tgttccgcgt
      181 ggccaactgc cgcaacgaca tgacagtgcg ggagctcaaa gaagagctgg acctgatggt
      241 cggcatcccc ttcaacctgc agcggctgca tttcctggac cgaggaattc tgatggatga
      301 tgctaccctg aagttctacg atgtcatccc cggagcactt atttcattat gtatctggca
      361 ttacgatggt tggacggaac tggttttggc cgccgtggaa ggggacccca gcaagatgtc
      421 atgtcttggc atcagcgagg ataccttcta ccgaacagcg aactcacagc attttaaggg
      481 ggaacagtgg aggcagtgga cagcccagag ggcatttgtg gccttgtaca tctctgctca
      541 cagaggccac gtggatgccg tgcagtatct tctaggactt ggagcaaact gcctggccaa
      601 atcacccctg ggcaggacgc ccctgcacgt ggtcgcagcc atgggcagga cagactgcgt
      661 ccagccctta ctggaacatg gtgcctccat ccatgacaga gacttgaaga gcgacacgcc
      721 catcaccatt gcgcggcgcc tgaagcgagg acatttagag cacaagatgt tccttctcta
      781 ctggatggtc aagtcggggt cccgggaccc ggacttggta gggaggaaag ctttggagaa
      841 atccagccct gggatggcga ccaggaggag cacaatatta atctcctgag tacatttgcc
      901 catcacaaga ctctgggacg accttacatc cccccccact gcctcccccc ccccatggca
      961 ctcactaggg aacagaaaga agggacagat ccaaatcaga
//
