LOCUS       NM_001407912            2835 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus ankyrin repeat domain 42 (Ankrd42), transcript variant
            2, mRNA.
ACCESSION   NM_001407912
VERSION     NM_001407912.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2835)
  AUTHORS   Yamauchi,S., Ito,H. and Miyajima,A.
  TITLE     IkappaBeta, a nuclear IkappaB protein, positively regulates the
            NF-kappaB-mediated expression of proinflammatory cytokines
  JOURNAL   Proc Natl Acad Sci U S A 107 (26), 11924-11929 (2010)
   PUBMED   20547855
  REMARK    GeneRIF: IkappaBeta regulates the NF-kappaB-mediated transcription
            of a wide variety of proinflammatory genes, playing a crucial role
            in the regulation of innate immune responses.
REFERENCE   2  (bases 1 to 2835)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104921.9 and AC158144.13.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133339.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1011              AC104921.9         49282-50292         c
            1012-1175           AC104921.9         44651-44814         c
            1176-1283           AC104921.9         38923-39030         c
            1284-1403           AC104921.9         37120-37239         c
            1404-1539           AC158144.13        1826-1961
            1540-1740           AC158144.13        6957-7157
            1741-1866           AC158144.13        8641-8766
            1867-1972           AC158144.13        10859-10964
            1973-2145           AC158144.13        16129-16301
            2146-2272           AC158144.13        29552-29678
            2273-2417           AC158144.13        31250-31394
            2418-2497           AC158144.13        36964-37043
            2498-2835           AC158144.13        39458-39795
FEATURES             Location/Qualifiers
     source          1..2835
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 51.52 cM"
     gene            1..2835
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /note="ankyrin repeat domain 42"
                     /db_xref="GeneID:73845"
                     /db_xref="MGI:MGI:1921095"
     exon            1..1011
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     CDS             954..2537
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /note="isoform 2 is encoded by transcript variant 2;
                     ankyrin repeat domain-containing protein 42"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 42
                     isoform 2"
                     /protein_id="NP_001394841.1"
                     /db_xref="GeneID:73845"
                     /db_xref="MGI:MGI:1921095"
                     /translation="MPGVANPGPSKSRRETADSSSRKKVHFSSIHDAVRAGDVKQLSD
                     IVERGANLNEVDALHQFTPLHWAAHSGSLECLHWLLWSGADATQTTTRGWTAAHIAAI
                     RGQDACLQALIINGANLATQDDRGCTPLHLAATHGHSFSLQIMLRSGVDPSVTDKREW
                     KPVHYASFHGRLGCLQLLVKWGCGIEDVDYNGNLPVHLAAMEGHLHCLKFLLSRMNSA
                     TQALKAFNDNGENVLDLAQRFLKQNVVEFIQGAQYEGSHPDDHDDLAFPGHVAAFKGD
                     LEVLKKLIGDGVINLNERDDNGSTPMHKAAGQGHIDCLQWLIEMGAESNITNKAGETP
                     SDVAKRFAHLAAVKLLEGLQKYEIDDIESDKDHINFFTRHGVEGSTDAKDDLCLSESD
                     KANARMRAHKKIVELRQLLEIAESNFKHLGGITEEDLKQKKEQLESKKTINELQGQLA
                     YERLRREKLECQLDEYRVEVDQLKETLQKIQVTSVAAMEDDSCESSKEKRRVKKKVSP
                     GGVFVRSYQRIRTSISSQV"
     exon            1012..1175
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1283
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1403
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1539
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            1540..1740
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            1741..1866
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            1867..1972
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            1973..2145
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            2146..2272
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..2417
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            2418..2497
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     exon            2498..2835
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2814..2819
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /note="hexamer: AATGAA"
     polyA_site      2835
                     /gene="Ankrd42"
                     /gene_synonym="4931426M20; 4933417L02Rik; Ikbn"
                     /note="major polyA site"
ORIGIN      
        1 actcgtttcc aaggtgacgg ccacgccgcc acgccctcca ggctgcggga actgagacgc
       61 tggaaaacga ctcggaggag agcgttcccg ccgacggcgg tcgccgtcac aaccacccgc
      121 gggcccagga aaccggagac tgtggtctcc gcgccaggcg ccgcgcatgt gctatccgcg
      181 gcccgcacgg ctacctcggc tccgggtcta gggggaaggt cgtgggagag caggcatcct
      241 gttgccacaa tcctagagaa agaaaccgag aaggagggga ccgcctcacc aggatctctt
      301 tggcaggagt tggtgaggac ggcggctttt cccgaaggga ctcgagaaga gccagtgaag
      361 acctagggca gcaccgctgc gtctctcagg agagaattag ggaacagcat ggccaccagc
      421 agagcagtcc acgggtggct gtgaggggcg acagcggcca atgcaagagc gacgcgagct
      481 taggtgaagt cgctggctcg cattcctgcg actcgagggc cgccgtcagc gaagacgcct
      541 gggtggacgt ccttaaaacc cgagggcccc gaaccagtga ttccggggcc caaggtagcg
      601 acgaccgcag cggttcttgg gaaggagcaa gtgtggatgg aagccgctgc ctcagtagtc
      661 cttgggaagg agtaagtgat gacagggcct acgaggccag agactcctct agggtgagca
      721 tcagcgaaga ctccagccgc ctcttccgta gctgctggga gagagaaagc gaagaagatt
      781 cctgctttag gggctcttgg gagagaaggg aggtttgtgg tccccgcacc agcgacgaag
      841 agtccagttc ttgcagcagt ggtccatgcg ggggatcaag tgaagacctc agcagcaggg
      901 acctgggctc cactcctccc cagagtccaa gaccgaggtc gaaggacaac accatgcctg
      961 gtgtggctaa tccaggcccc tccaagtccc gtagggagac tgcagactca agttccagga
     1021 agaaggtaca tttcagtagc atacatgatg cggtccgggc tggagatgtc aagcagctgt
     1081 cagacatagt ggagcgtggt gccaacctta atgaagtgga tgctctccat cagtttactc
     1141 ctttacattg ggcagcacat tctggaagtt tagagtgcct tcactggcta ctctggagtg
     1201 gtgctgatgc cacacagaca actacaaggg gatggacagc ggctcacata gctgcaatcc
     1261 ggggtcagga tgcctgctta caggctctta taatcaatgg agccaaccta gcaactcaag
     1321 atgatcgtgg atgcacccca ctacaccttg ctgctactca tggacactct ttttctttac
     1381 aaataatgct gcgaagtgga gtggatccca gcgtgactga caagagagag tggaaacctg
     1441 tgcattatgc atcttttcat gggcggcttg gttgcttgca acttcttgtc aaatggggat
     1501 gtggcatcga agacgtggac tacaatggaa acctcccggt tcatttagca gccatggaag
     1561 gccacctcca ttgtttgaaa ttcctactga gtagaatgaa cagtgcaaca caagccttaa
     1621 aagccttcaa tgataatgga gaaaatgtat tggacctggc ccagcggttt ttgaaacaga
     1681 atgttgtaga gtttattcag ggggctcagt atgaaggaag ccatccagat gatcatgatg
     1741 atttagcctt tccaggtcat gtggctgcct ttaagggtga cttagaagtg cttaagaaac
     1801 tgataggaga cggggtaatc aatctgaatg aacgcgatga taatggatca actcccatgc
     1861 ataaagctgc tggacagggc cacattgatt gtttgcagtg gttaattgaa atgggagccg
     1921 aaagcaatat taccaacaaa gcaggagaga cccccagtga tgtggctaag agatttgccc
     1981 atttggctgc agtgaaactc ttggaggggc tacagaaata tgaaatagat gacattgaga
     2041 gtgataaaga tcatataaat ttttttacaa ggcatggtgt tgaaggaagc accgatgcca
     2101 aggatgactt atgtctgagt gaatcagaca aagcaaatgc cagaatgaga gctcataaga
     2161 aaattgtaga attgagacaa cttcttgaaa tcgctgagag caactttaaa cacttgggtg
     2221 ggataaccga agaggattta aagcagaaga aagaacagct ggagtctaag aagaccatca
     2281 acgagctgca gggccagctg gcctatgagc gactccgcag ggaaaagtta gagtgccagc
     2341 tggatgagta tcgagtggaa gtggatcaac tcaaggaaac gctgcagaaa atccaggtca
     2401 ccagtgtcgc ggctatggaa gatgactcgt gtgagtctag caaagagaag cggcgagtga
     2461 aaaaaaaagt gtcacctggg ggtgtgtttg tgagaagtta tcagaggata aggacttcta
     2521 tatcaagcca ggtttgagtg acagcttttc aacataaaga catacaacat aagaataaaa
     2581 taccaaacac ttcatttagt ccacaagccc tttgaagagt ttgtagtgag tacattctat
     2641 ggagtgagca gcagcggcag cagcggcggc agcagcagcg gcagcatcat cgtcagttct
     2701 ccttccagaa cctataaaac cccaatgcta tcgccaagca agtgaacact gaggctgtga
     2761 aaagaaagaa actatgttac aagctatagc taattatttc agacaataaa agaaatgaac
     2821 agaaacaaaa tcaaa
//
