LOCUS       NM_001356538            3512 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ankyrin repeat domain 35 (Ankrd35), transcript variant
            2, mRNA.
ACCESSION   NM_001356538 XM_006501254
VERSION     NM_001356538.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3512)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3512)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112261.4.
            
            On Oct 7, 2017 this sequence version replaced XM_006501254.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC157973.1, SRR7974084.30918.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849379, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-319               AC112261.4         110143-110461       c
            320-450             AC112261.4         102329-102459       c
            451-539             AC112261.4         101324-101412       c
            540-604             AC112261.4         100898-100962       c
            605-662             AC112261.4         100064-100121       c
            663-733             AC112261.4         99895-99965         c
            734-840             AC112261.4         99524-99630         c
            841-1025            AC112261.4         98381-98565         c
            1026-1063           AC112261.4         97561-97598         c
            1064-3055           AC112261.4         95418-97409         c
            3056-3145           AC112261.4         91357-91446         c
            3146-3211           AC112261.4         91082-91147         c
            3212-3316           AC112261.4         90296-90400         c
            3317-3512           AC112261.4         89558-89753         c
FEATURES             Location/Qualifiers
     source          1..3512
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.94 cM"
     gene            1..3512
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /note="ankyrin repeat domain 35"
                     /db_xref="GeneID:213121"
                     /db_xref="MGI:MGI:2442590"
     exon            1..319
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             281..3271
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /note="isoform 1 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 35
                     isoform 1"
                     /protein_id="NP_001343467.1"
                     /db_xref="CCDS:CCDS38558.1"
                     /db_xref="GeneID:213121"
                     /db_xref="MGI:MGI:2442590"
                     /translation="MKRIFSCSSSQVAVEKWNRRDQKLLEAVQRGDVGRVAALASRKS
                     ARPTKLDSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQC
                     VKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIA
                     SLGGHAAICSQLLQRGARVNVTDKDDKSALILACEKGSAEVAELLLSHGADAGAVDSL
                     GHNALHYALRTQDKELWRLLQQALNRRRRGGHGLVQHPDHPSQASSCEPRVGSPPKNS
                     RKVEPEEEQEEEGEERCSEEWRWKFEEEQRKVHQLEQELVRKTDECKAHAAAFSSLEE
                     QIREQAQELGHLLVQEPGAPGNQGPGLRPEGDGMEEGCPLNLLAERIQELKKQQKALA
                     TINPTLVPKRAEELAPAEIHHEVHRKSQPEQGLPQGPSSETTGKATGQQPNTNGGQNL
                     GLQNTEQVCAGQKERTPAPGTETAGTVGEPVGIAMNQLLLQLREELAAVWREKDAARG
                     ALSRPVLEGALGTPRAEAAAAAWEKMEARLERVLVRLDGAKMGLHVKPEVPVQGSRDG
                     APKAVPGCSKEQEEKKALGTRGEPLGAPGKEQALGGGLAKGQLEKEVSALRLSNSNLL
                     EELGELGRERQRLQGELQSLTQRLHREFVPKPEAQVQLQQLRRSVGMLTEELAMEKEA
                     TDKLRRLLASQTSGLQGLWKCLPPDLVGKGNTQSTAAEPLEELQACISTLVDRHLEAQ
                     RVLARLEEENQQLRGSLAPCGEPEASLKVTASPQVAALEEDLGMLEEELRAVQATMSG
                     KSQEICKLKQLLYQATEEVAELRAREAASLRQHEKTRGSLVAQAQAWGQELKVVLEKY
                     NTACREMTRLRDTVAEERRRSEDLAARAAEQERQAGEMRGRSEQFEKTAELLKEKTNH
                     LIGACRDKEAKIKELLKKLEQLSEEVLEVRGENAHLALQLQDSQKNHEEIISTYRSHL
                     LNAARGYMEQDVYNILLRILSMQE"
     exon            320..450
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            451..539
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            540..604
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            605..662
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            663..733
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            734..840
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            841..1025
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1063
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..3055
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3056..3145
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3146..3211
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3212..3316
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3317..3512
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3490..3495
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3512
                     /gene="Ankrd35"
                     /gene_synonym="4732436F15Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaagggcgga acttgagagc cagccagggt ggccgcaaaa gactgcgggc tttttgcctc
       61 tgcagggacg gggttaggca gggccagagg cggggtttta agcccagcct tcagttgaac
      121 gtctacgatt gagcggggtg ggatctgggg cggggcttgg ggcgggaccc agtctgcttt
      181 ttgacagctg tctttcggca cagccgtagc cgagttgggt taggaacttg tggcccggct
      241 ctctgcgcgt ccccgtcccc ccgtggccct agccccggcc atgaagcgca tcttctcctg
      301 ctccagttca caagtggcgg tggagaaatg gaaccgacgt gatcagaagc tgctggaggc
      361 ggtgcagcgg ggggacgtgg gacgcgtggc tgccttggcc tctaggaagt cagcccgacc
      421 caccaaacta gactcaaatg gccagtcccc gttccatctg gcagcctcca aaggcctgac
      481 agagtgtctg acaatactgc ttgcaaatgg ggctgatatc aacagcaaga acgaggacgg
      541 aagcactgcc cttcatttgg ccaccatctc ctgtcagcca cagtgtgtga aggtcttgct
      601 tcagcacggt gctaatgaag atgctgtgga tgcagaaaat cgcagtccat tacactgggc
      661 agcctcctct ggctgcgcct caagtgtcct cctgctgtgt gaccacgaag ccttcctgga
      721 cgtgctggat aatgatggac gcacacccct gatgattgca tcgctgggtg gtcatgcagc
      781 tatctgctca cagctgttgc agagaggtgc ccgagttaat gtcacagaca aggatgacaa
      841 atcagctttg atcctggcct gtgagaaagg cagcgctgag gtggccgagc tgctcctgag
      901 ccatggagcg gacgctggag cggtggacag tttgggacac aacgctcttc attatgcttt
      961 gcgtacacaa gacaaggagc tgtggaggct gttacagcag gccctgaacc ggcggcggag
     1021 aggcggtcat ggactggttc aacacccaga tcacccatct caggcctctt catgtgagcc
     1081 tcgggtggga tctcctccta agaactcacg gaaagtggag cctgaggaag agcaggagga
     1141 ggagggggag gagcggtgct cagaagagtg gaggtggaag ttcgaggagg agcagaggaa
     1201 agttcatcag ctggagcagg agctcgtgcg aaagacagat gagtgcaagg ctcacgctgc
     1261 agccttctca agcctagagg agcagattcg agagcaagcg caagaactag gccatctcct
     1321 agtgcaagaa ccgggagctc caggaaatca aggccctggt ctccggcctg agggagatgg
     1381 tatggaggag ggttgtcccc tgaacctgct ggctgagcgg atccaagagc tgaagaagca
     1441 gcagaaggca ctggctacaa taaacccaac attagttccc aagagagctg aagaattagc
     1501 cccggctgag atccatcatg aagtacacag aaagtcccaa ccagagcagg ggctgcccca
     1561 gggcccaagt tcagaaacca ccgggaaagc cacaggacag caaccaaaca ccaatggggg
     1621 gcagaacctt ggcctccaga acactgagca ggtgtgtgct ggccagaagg agaggacccc
     1681 agctccaggg actgaaacag caggcacagt gggagaacca gtgggcatag ccatgaatca
     1741 gctcctccta cagctaaggg aagagctggc tgcagtgtgg cgagaaaagg atgctgccag
     1801 aggggctttg tcaagaccag ttctggaggg agccctgggg actcccagag ctgaggctgc
     1861 agcagctgcc tgggaaaaga tggaagccag gcttgagagg gtgctggtaa ggttagatgg
     1921 agcaaagatg ggactgcatg tgaaacctga ggtccctgtc caggggtcca gagacggagc
     1981 cccgaaggca gtcccgggat gctctaaaga gcaggaagaa aagaaggctc ttggaaccag
     2041 aggagagccc ttaggggccc ctggaaaaga acaggcctta ggaggaggcc tggcaaaggg
     2101 acagctggag aaagaggtgt cagctttgag actgagcaat agcaacttgc tggaggaatt
     2161 gggagagttg gggcgcgaga gacaacgctt gcagggagag ctgcagtcct tgacccagag
     2221 gctacaccgg gagtttgtgc ccaagcccga ggcacaggtc cagctacagc agttgcggag
     2281 gagcgtgggg atgttgacag aggaactggc catggagaag gaggccacag ataagctgcg
     2341 caggctactg gcctcccaga ctagcggcct ccaaggactg tggaaatgcc tacccccaga
     2401 cctcgtgggc aaggggaata cacagagtac agctgcagaa cccctggagg agctgcaggc
     2461 ctgcatcagc accctggtgg ataggcacct tgaggctcaa cgggtgctgg ctcggttgga
     2521 agaggaaaac cagcagctga ggggatcctt ggctccctgt ggggaaccag aggcctccct
     2581 caaggttaca gcatccccgc aagtggccgc cctggaggaa gatctgggaa tgctagagga
     2641 agagctacgg gccgtgcagg ccacgatgag tgggaagagc caggagattt gcaagctgaa
     2701 acaactgctc taccaagcca cggaagaagt ggccgagctg agagctcggg aagcagccag
     2761 cctgcgccag cacgagaaga cgcgaggctc gctggtggcc caggcacagg cttggggcca
     2821 ggagctcaaa gtcgtgctgg agaagtacaa cacagcctgt cgggaaatga ctcgattgcg
     2881 ggacactgtg gcggaggaac gtcgccgcag cgaggacctg gcggctaggg cggcggagca
     2941 ggagcgccag gctggcgaga tgcgcgggcg ctcggagcag ttcgagaaaa ctgctgagct
     3001 cctgaaagag aagacaaacc acctcatcgg ggcttgccgg gacaaggaag ccaagatcaa
     3061 ggagttgctg aagaagctcg agcagctttc ggaagaagtt ctagaagtcc ggggcgagaa
     3121 tgcccacctc gccctacagc tgcaggactc ccagaagaac cacgaagaga tcatctccac
     3181 atacaggagt catctactga atgctgctcg gggctacatg gaacaagacg tctacaacat
     3241 cctacttcga atcctcagca tgcaggagtg aggcaggctc actgtgtgcc ctcagggata
     3301 aaggcatttc tcttttggaa taatgaggct cgatcaagct gtggtgggca ggtgggtgga
     3361 cggtgattac ccactagtgg tgctgtgggt ggggcttcac aggacacacg aactccagac
     3421 ctgaaaacct ggaccctgga atcagcacag atgagaccag aattgtggat gtaaattagc
     3481 tccgtggaaa ataaagcaga aaacagatgg tc
//
