LOCUS       NM_175455               3956 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ankyrin repeat domain 34B (Ankrd34b), mRNA.
ACCESSION   NM_175455
VERSION     NM_175455.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3956)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   2  (bases 1 to 3956)
  AUTHORS   Al-Shaibi,N. and Ghosh,S.K.
  TITLE     A novel cell-surface protein CSP82 on bone marrow stem cells and a
            cytosolic phosphoprotein DP58 (ankyrinRD 34B) are involved in
            promyeloid progenitor induction
  JOURNAL   Cell Immunol 258 (2), 172-180 (2009)
   PUBMED   19524877
  REMARK    GeneRIF: Cytosolic phosphoprotein DP58 is involved in promyeloid
            progenitor induction.
REFERENCE   3  (bases 1 to 3956)
  AUTHORS   Al-Shaibi,N. and Ghosh,S.K.
  TITLE     A novel phosphoprotein is induced during bone marrow commitment to
            dendritic cells
  JOURNAL   Biochem Biophys Res Commun 321 (1), 26-30 (2004)
   PUBMED   15358210
  REMARK    GeneRIF: Because of its restricted expression in bone-marrow-drived
            progenitors as a phophorylated protein, it is likely that DP58 may
            be involved in a signaling pathway for cellular differentiation.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK078203.1, BC119314.1, AK138465.1, BE649643.1 and AW489260.1.
            
            On Apr 4, 2008 this sequence version replaced NM_175455.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC096609.1, AK090387.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               AK078203.1         75-212
            139-2220            BC119314.1         1-2082
            2221-3212           AK138465.1         2407-3398
            3213-3582           BE649643.1         14-383
            3583-3956           AW489260.1         1-374               c
FEATURES             Location/Qualifiers
     source          1..3956
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 47.68 cM"
     gene            1..3956
                     /gene="Ankrd34b"
                     /gene_synonym="6430502M16Rik; DP58"
                     /note="ankyrin repeat domain 34B"
                     /db_xref="GeneID:218440"
                     /db_xref="MGI:MGI:2443245"
     exon            1..233
                     /gene="Ankrd34b"
                     /gene_synonym="6430502M16Rik; DP58"
                     /inference="alignment:Splign:2.1.0"
     exon            234..378
                     /gene="Ankrd34b"
                     /gene_synonym="6430502M16Rik; DP58"
                     /inference="alignment:Splign:2.1.0"
     exon            379..461
                     /gene="Ankrd34b"
                     /gene_synonym="6430502M16Rik; DP58"
                     /inference="alignment:Splign:2.1.0"
     exon            462..520
                     /gene="Ankrd34b"
                     /gene_synonym="6430502M16Rik; DP58"
                     /inference="alignment:Splign:2.1.0"
     exon            521..3940
                     /gene="Ankrd34b"
                     /gene_synonym="6430502M16Rik; DP58"
                     /inference="alignment:Splign:2.1.0"
     CDS             544..2070
                     /gene="Ankrd34b"
                     /gene_synonym="6430502M16Rik; DP58"
                     /note="cytosolic phosphoprotein DP58; dendritic
                     phosphoprotein 58 kDa; dendritic protein of 58 kDa;
                     dendritic cell progenitor protein of 58 kDa"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 34B"
                     /protein_id="NP_780664.2"
                     /db_xref="CCDS:CCDS26681.1"
                     /db_xref="GeneID:218440"
                     /db_xref="MGI:MGI:2443245"
                     /translation="MDEGSEVSTDGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGE
                     TPLMIACKTKHVDQQSVGRAKMVKYLLENSADPNIQDKSGKSALMHACLERAGPEVVS
                     LLLKSGADLSLQDHSGYSALVYAINAEDRDTLKVLLSACQAKGKEVIIITTAKSPSGR
                     HTTQHHLNMPPADMDGSHPPATPSEIDIKTASLPLSYSSETDLTLFGFKDKELCGGSD
                     NTWDPDSPPRKPVIATNGPKLSQAPAWIKSTPSLKHQARVASLQEELQDITPEEEIAY
                     KTNALALSKRFITRHQSIDVKDTAHLLRAFDQVNSRKMSYDEINYHSLFPEGSQTSVE
                     IPTDRDPDSNQIFASTLKSIVQKRNSGANHYSSDSQLAEGVTPPTVEDGKAAKKKIFA
                     PSPSLLSGSKELVEPAPPGPLSRRNHAVLERRGSGAFPLDHSLAQSRPGFLPPLNVNP
                     HPPITDIGVNNKICGLLSCGQKALMPTAPIFPKEFKTKKMLLRRQSLQTEQIKQLVNF
                     "
     regulatory      3921..3926
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ankrd34b"
                     /gene_synonym="6430502M16Rik; DP58"
                     /note="hexamer: AATAAA"
     polyA_site      3940
                     /gene="Ankrd34b"
                     /gene_synonym="6430502M16Rik; DP58"
                     /note="major polyA site"
ORIGIN      
        1 agcggaagcg ccagccccgc gtctggcgag gtgcgcgcct cgccgctccc gctccagcgc
       61 ttcgtggccc gcctgtgtct gcagggcagg ggcgggggcc cggtgacacg gacaggggac
      121 tgagatcgca gtcgccgccg aatcgtcgac agtcacccag ctcggacgga gcgtccgagc
      181 aggagccgat caggaaggtg aaggaccact gccgagccga cagcgcgtcc cagcaccttg
      241 gacttgctct ctcctgaact ggggaaaatc tgaggaaacc aggcacggac cttggagaca
      301 cgccgcctgc acactcaaca gtctggaaat ccagccacct tggtacctcg ccgcttccca
      361 gacactttgg aggagcagga gctgacagct ggctgacaga aacctcatcc aaagagagaa
      421 gagactaaac ccaagtatga aattagggat gatgttttca gagtagacct gcaagtcggt
      481 atccacactg ccatcctgat cgctgcatcc cacatctcag gtattgattt ctgacttttg
      541 aagatggatg aaggctcaga agtttcaacg gatggaaatt ccttgatcaa agcagtacat
      601 cagagcaggc ttcgcctcac tagacttttg ctagaaggtg gcgcctacat caacgaaagc
      661 aacgaccgtg gggaaacccc tttaatgatt gcttgtaaga ccaaacatgt cgatcaacag
      721 agcgtcggta gagccaagat ggttaaatac ctcttagaga acagcgctga ccccaacatc
      781 caggacaaat ccgggaaaag tgccctgatg cacgcatgct tggaaagagc cggcccagag
      841 gtggtttcct tgctcctcaa gagcggggcc gatctcagct tgcaggacca ttctggctac
      901 tcagctctgg tttatgctat aaatgcggaa gacagagata ccctgaaagt cctccttagt
      961 gcttgccagg caaagggcaa agaggttatc attataacca cagcgaagtc gccctctggg
     1021 aggcacacca cccagcacca cctaaacatg cctcccgcag acatggacgg gagccatccc
     1081 ccggccacgc cttcggaaat tgacatcaaa acagcctcgt tgccactttc ctattcttct
     1141 gagacggacc tgacactctt tggcttcaag gataaggagt tgtgtggggg cagtgataat
     1201 acctgggacc cagactctcc tccgaggaag cctgtgatag ccactaatgg gcccaagcta
     1261 tcccaggctc cagcctggat caagagtacc ccatcattaa agcaccaggc cagagtggcc
     1321 tccttgcaag aggagctcca agatatcact ccagaggaag aaatagccta caaaaccaac
     1381 gcgctggcac tctctaagcg gttcatcacc aggcaccaga gcatcgatgt aaaagacact
     1441 gcacacttgc tcagggcctt tgaccaggtc aactcaagga aaatgtcata tgatgaaata
     1501 aattaccatt ccttgtttcc agaaggaagc cagacaagcg tggagattcc cactgaccgg
     1561 gacccagact ctaatcagat ttttgcctcc acgctgaaga gtatagttca aaagcgaaac
     1621 tctggggcca atcactacag ctctgattcg cagctcgctg agggtgtcac ccctccaacc
     1681 gtagaagatg gcaaagctgc aaagaaaaag atcttcgcgc catctccttc cttgctttca
     1741 gggtccaaag aattagtgga gcctgctcct ccaggccccc tgagcaggag gaatcacgcg
     1801 gtgttggaaa ggcgtggttc cggggctttc cccttagacc acagtctggc gcagagcaga
     1861 cccggctttc tgccgccctt gaatgtgaat cctcaccctc ccattacaga cattggtgtc
     1921 aacaacaaga tctgcggcct gctttcttgt ggccaaaaag cgcttatgcc gacggcccct
     1981 attttcccga aagaatttaa aaccaaaaag atgctgttaa ggaggcagtc cctgcagacg
     2041 gaacaaatta agcaattagt aaatttttaa gagatcatta ggaaacacat tatgttcaaa
     2101 tcagaaatac atagacttag agaagaaatc ttaactatat ccttttaagt cttagctagt
     2161 gcatcgcagc taggcaaatc aaaatatagt gtattttgta ttaggtaccg cgagcacagc
     2221 ttaatacata gcttctgagg gaattctaac aaaatgaaag ctgttttttt tctcaaaatg
     2281 tccaatattt atcaactttc atgtggtcca cgttttttca tctaaccaaa acatcaccaa
     2341 gaaagaaagt ttcctgtgtt agaaacactt ttaacatttc agattggctt catgttctat
     2401 tatgaaacaa tgctctcaag tcagtaattt tgtggacact ttatgtcaac aaggttgtag
     2461 tttttcatgt tgccaaaatc aaacaaaaca ctgacatcag taaagcgaaa actacaaagg
     2521 aagaataaat ggatcccttt aaaaatgttg actcaggcaa gtaaaagtct aattaaactt
     2581 tgaaagcatg aaaactagat cgacagagca agcagtgttc acagtggctg ctaactatgt
     2641 atcagaacgg cagctggggg tggggcgggg gcggaggaga tggctcatgg gccctgcaag
     2701 ccgaatggcc cctttggatg cccagaatgc acgtgacagt agtgcaggca tctgtaatcc
     2761 cagcattccc tgtggggcga tgggtggagc caggagaatc cctagaaacg catggctcag
     2821 atagtctgtc tacactgcag ttaagaaacc ctgtctcaaa caagggaaca aggatgactg
     2881 ataccaaagg ctgtcctctg acaggccgac tccccatgcg aggcagcaat gcgcgtacca
     2941 aagcctgttg tttttacgcc atacattgct ttcaaacaaa cttaccaatc atgttatctt
     3001 atggaattac tcctgttatt tttgagtatt ttctccatag gtttccaata tcaaggtaat
     3061 ataaaaagta aaaaggattc accctgatat acattcttcc caaaaaaaac ccacccaaaa
     3121 cagaccgggg tgggggtggg ggtgggggtg gggctgggga gcaagaagtt tgggaataac
     3181 aaaaagaggg aattaaacgc ttgcttcatg ttaaaaaaaa aaaaagaaac aatgattaat
     3241 agattagttt agtttaggta aaattacaaa atccaagtag aaacctaatc ataaggtgtg
     3301 ttacagggtc actactaagc aatatcttta tttctgacat gtagttatta gacagtcatt
     3361 ataaagatat ataaagataa cgtccttggt gtgacatctg gatcatctag tattttaggg
     3421 tctatgaata acttgtaaca aaatacacat tactataaga tatttaaaaa gtgacaatat
     3481 tacctacatg acttcaaagt atagtgttca cagagttctt cactctggca gttctgaagc
     3541 aaagagcaac cgatgcacta gaaaaccaag ggtgtgagtc caatgacatc atctccagct
     3601 tcatttcttt gcccaacagg tggcacgagg cctttcttgg taatttgata taagcatttt
     3661 gaaatgtaca tagaaattat ttaattattt gtggctttta tttaaaaaac taaattgcag
     3721 gtttttccat ttaatgtttt gaagagactc ttaattacat tagaaatatt ttttattcag
     3781 aaattaaaat tgtactgatg tttctaagta gctgaattcc tttcgcaagt tttaatatca
     3841 caaaaagtac ttgacctcac atggtaaggt gacagttgga agaatatgta aatagagtaa
     3901 ttcattatca aggtggtatc aataaagatt taaaatatca aaaaaaaaaa aaaaaa
//
