LOCUS       NM_133971               2291 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ankyrin repeat domain 10 (Ankrd10), transcript variant
            1, mRNA.
ACCESSION   NM_133971
VERSION     NM_133971.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2291)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2291)
  AUTHORS   Yoshikawa,T., Piao,Y., Zhong,J., Matoba,R., Carter,M.G., Wang,Y.,
            Goldberg,I. and Ko,M.S.
  TITLE     High-throughput screen for genes predominantly expressed in the ICM
            of mouse blastocysts by whole mount in situ hybridization
  JOURNAL   Gene Expr Patterns 6 (2), 213-224 (2006)
   PUBMED   16325481
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK050983.1, AK082875.1, AK084456.1 and AV319211.1.
            
            On Aug 13, 2013 this sequence version replaced NM_133971.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK082875.1, AK088371.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AK050983.1         2-4
            4-1533              AK082875.1         1-1530
            1534-2289           AK084456.1         1644-2399
            2290-2291           AV319211.1         249-250
FEATURES             Location/Qualifiers
     source          1..2291
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 5.73 cM"
     gene            1..2291
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /note="ankyrin repeat domain 10"
                     /db_xref="GeneID:102334"
                     /db_xref="MGI:MGI:1921840"
     exon            1..347
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..1388
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ankyrin repeat domain-containing protein 10"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 10
                     isoform 1"
                     /protein_id="NP_598732.2"
                     /db_xref="CCDS:CCDS22098.1"
                     /db_xref="GeneID:102334"
                     /db_xref="MGI:MGI:1921840"
                     /translation="MSAGAGAAVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHT
                     PRAHLAAEDSFYGWTPVHWAAHFGKLECLMQLVRAGASLNVSTTRYAQTPAHIAAFGG
                     HPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECITALVGSGAHTDLRNASGLTA
                     ADIAQTQGFQECTQFLLSLQNHQMSRFCHNGTLSGGHESILPTHVSLGTNRKRCLEDS
                     ESLGVKKARTRVPSLDHAMPLANGEAEDDADRMHVDRECAAVSDMKNSSSVLNTLTNG
                     SVVNGHLDFPCANQLNGMESRSHPCLTGSNGVSNGQPLSSGQASVSANGTEEPEKTMG
                     INPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHT
                     SCVRVEQRYDSAVLGAMQLHHGS"
     exon            348..500
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            501..592
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            593..828
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            829..924
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            925..2291
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2270..2275
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2289
                     /gene="Ankrd10"
                     /gene_synonym="4833425P12Rik"
                     /note="major polyA site"
ORIGIN      
        1 ctcagtgctc gctgcgctcg gatgcggatg ggacgcggca gcagctcgcc tgtcctttgt
       61 gttcgagtgg cggcagcttc gcaggccttc accggcacat tcctctggcc gatcagtcgc
      121 gtgcttccta gcgacccatc atgtcagcgg gagcgggcgc ggccgtggag gcaggcttct
      181 ccagcgagga gctgctgtcg ctccgcttcc cgctgcaccg cgcctgccgg gacggggacc
      241 tggtcgcgct ctgttcgctg ctgccacaca cgccgcgcgc tcacctggcc gctgaggact
      301 ccttctacgg ctggacgccc gtgcactggg ctgcgcactt cggcaagttg gagtgcttaa
      361 tgcagttggt aagagcagga gcctcactga atgtctcgac cacccgctat gcccagaccc
      421 cagcccacat cgctgctttt ggaggacatc ctcagtgtct ggtctggctg attcaagctg
      481 gggccaacat taacaaaccg gactgtgagg gggaaactcc cattcacaag gcggcccgct
      541 cagggagcct cgagtgcatc actgccctgg tagggagcgg ggctcacacc gacctgagaa
      601 atgccagtgg cctgacagca gcagacattg cacaaaccca gggtttccaa gagtgcaccc
      661 agtttctctt gagcctccag aaccatcaaa tgagccgttt ctgtcataat ggcaccttga
      721 gtggaggtca tgagagcata ctgcccactc acgttagcct gggaacaaac cgaaagagat
      781 gcctggaaga ctcagaatct ttgggagtga agaaagctag aaccagagtt cccagcctgg
      841 atcacgccat gcctctagca aatggagagg ctgaagatga tgccgacaga atgcacgtgg
      901 acagagagtg tgctgctgta tcagatatga aaaacagtag ctccgtgttg aatacattga
      961 caaatggaag tgtcgtcaat ggacatttgg acttcccctg cgcgaaccag ctcaatggga
     1021 tggagagcag gagtcacccg tgcttaacag gatctaatgg cgttagcaat ggacagccat
     1081 tgtccagtgg ccaggcctct gtctctgcta atgggactga ggagccagaa aagaccatgg
     1141 gcattaaccc cgagatgtgt gggtctctcc atctgaacgg gagcccaagt agctgtgtgg
     1201 ccagcaggcc gtcctgggtg ggggacatag gggagagctt gcactacgga cactaccatg
     1261 gatttgggga cactgctgag agcatccctg agctaagcag tgtgctggag cacacgagct
     1321 gtgttcgggt ggaacagcgc tacgacagtg ctgtcctggg cgctatgcag ctgcaccacg
     1381 gctcctgagc ccagcgttac ctcagttcct ctgcagtgcc agcttgagga agctggacag
     1441 cctgtgctgt aggtgcctcg gctttctgag agagagtgag tccttggatt ccttcacgta
     1501 gagtgctgct ctgtgcatag acccttctca tggcgtggca ggcctcctgc gaggggtgct
     1561 ttggaggctt ctcttgtttg acaccagcct tttttttccc cacatcacga gacattgcca
     1621 cctttttgtg aattgtattt gatcaggaca gttgggcatc gctcaccttt actgtttgct
     1681 gtagcactcc tgatgacaca gctttcccct gtgcaaggac ctttacagtg tgcagcaacc
     1741 ccgggaaggg ggctgactgc tgcaggtgcg ctcagtggtc ggatgtgcta gccccttccc
     1801 tccctgtgta gactgctgcc tgtgtctcct tagaaacagc tctgcccagg atggattagg
     1861 ttgttgtttt tactccacat ttatacttga tctctagact tttttaccac aaacaatggt
     1921 ttcctttata tacagtggat gttgctgttt gtaggaactg tcgggtcaga atattttact
     1981 atggtgacct atttttttgt tactgttttt tgaagttttc tgcttaaaga tatataccac
     2041 tatatatcca gttaactgag agaattttgg gtttctctta ttaaagctgc attaaattcg
     2101 tgattttata gaaattagct tttgtttagg caactagtgg ctatacagca aatacccaat
     2161 gacttctgat ttttgtaata actatcagtg caagtgaact gtgaggtgac aaagccaatg
     2221 ttttaagagt gtactagcat tttgttttca agctgttctt tacaaattga ataaagaaaa
     2281 tgcactgctg a
//
