LOCUS       NM_013468               1765 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus ankyrin repeat domain 1 (Ankrd1), mRNA.
ACCESSION   NM_013468
VERSION     NM_013468.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1765)
  AUTHORS   Liu,L., Jiang,Q., Du,C., Yang,T., Zhou,L., Chen,J., Gu,L., Wang,Q.,
            Wang,Z., Wang,H. and Wang,L.
  TITLE     Ankrd1 regulates endogenous cardiac regeneration in mice by
            modulating cyclin D1
  JOURNAL   Eur J Pharmacol 983, 177005 (2024)
   PUBMED   39299480
  REMARK    GeneRIF: Ankrd1 regulates endogenous cardiac regeneration in mice
            by modulating cyclin D1.
REFERENCE   2  (bases 1 to 1765)
  AUTHORS   Han,S., Guo,J., Kong,C., Li,J., Lin,F., Zhu,J., Wang,T., Chen,Q.,
            Liu,Y., Hu,H., Qiu,T., Cheng,F. and Zhou,J.
  TITLE     ANKRD1 aggravates renal ischaemia-reperfusion injury via promoting
            TRIM25-mediated ubiquitination of ACSL3
  JOURNAL   Clin Transl Med 14 (9), e70024 (2024)
   PUBMED   39285846
  REMARK    GeneRIF: ANKRD1 aggravates renal ischaemia-reperfusion injury via
            promoting TRIM25-mediated ubiquitination of ACSL3.
REFERENCE   3  (bases 1 to 1765)
  AUTHORS   Abou Nader,N., Charrier,L., Meisnsohn,M.C., Banville,L.,
            Deffrennes,B., St-Jean,G., Boerboom,D., Zamberlam,G.,
            Brind'Amour,J., Pepin,D. and Boyer,A.
  TITLE     Lats1 and Lats2 regulate YAP and TAZ activity to control the
            development of mouse Sertoli cells
  JOURNAL   FASEB J 38 (9), e23633 (2024)
   PUBMED   38690712
REFERENCE   4  (bases 1 to 1765)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 1765)
  AUTHORS   Zhang,Y., Zhou,L., Fu,Q. and Liu,Z.
  TITLE     ANKRD1 activates the Wnt signaling pathway by modulating CAV3
            expression and thus promotes BMSC osteogenic differentiation and
            bone formation in ovariectomized mice
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1869 (5), 166693 (2023)
   PUBMED   36958710
  REMARK    GeneRIF: ANKRD1 activates the Wnt signaling pathway by modulating
            CAV3 expression and thus promotes BMSC osteogenic differentiation
            and bone formation in ovariectomized mice.
REFERENCE   6  (bases 1 to 1765)
  AUTHORS   Ruiz-Lozano,P., Smith,S.M., Perkins,G., Kubalak,S.W., Boss,G.R.,
            Sucov,H.M., Evans,R.M. and Chien,K.R.
  TITLE     Energy deprivation and a deficiency in downstream metabolic target
            genes during the onset of embryonic heart failure in RXRalpha-/-
            embryos
  JOURNAL   Development 125 (3), 533-544 (1998)
   PUBMED   9425147
REFERENCE   7  (bases 1 to 1765)
  AUTHORS   Baumeister,A., Arber,S. and Caroni,P.
  TITLE     Accumulation of muscle ankyrin repeat protein transcript reveals
            local activation of primary myotube endcompartments during muscle
            morphogenesis
  JOURNAL   J Cell Biol 139 (5), 1231-1242 (1997)
   PUBMED   9382869
REFERENCE   8  (bases 1 to 1765)
  AUTHORS   Jeyaseelan,R., Poizat,C., Baker,R.K., Abdishoo,S., Isterabadi,L.B.,
            Lyons,G.E. and Kedes,L.
  TITLE     A novel cardiac-restricted target for doxorubicin. CARP, a nuclear
            modulator of gene expression in cardiac progenitor cells and
            cardiomyocytes
  JOURNAL   J Biol Chem 272 (36), 22800-22808 (1997)
   PUBMED   9278441
REFERENCE   9  (bases 1 to 1765)
  AUTHORS   Arber,S., Hunter,J.J., Ross,J. Jr., Hongo,M., Sansig,G., Borg,J.,
            Perriard,J.C., Chien,K.R. and Caroni,P.
  TITLE     MLP-deficient mice exhibit a disruption of cardiac
            cytoarchitectural organization, dilated cardiomyopathy, and heart
            failure
  JOURNAL   Cell 88 (3), 393-403 (1997)
   PUBMED   9039266
REFERENCE   10 (bases 1 to 1765)
  AUTHORS   Zou,Y., Evans,S., Chen,J., Kuo,H.C., Harvey,R.P. and Chien,K.R.
  TITLE     CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5
            homeobox gene pathway
  JOURNAL   Development 124 (4), 793-804 (1997)
   PUBMED   9043061
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC119234.10.
            
            On Mar 21, 2007 this sequence version replaced NM_013468.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC037138.1, AK146627.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                AC119234.10        92505-92594
            91-270              AC119234.10        92951-93130
            271-408             AC119234.10        93986-94123
            409-516             AC119234.10        94408-94515
            517-615             AC119234.10        95480-95578
            616-714             AC119234.10        96778-96876
            715-813             AC119234.10        97052-97150
            814-912             AC119234.10        97274-97372
            913-1765            AC119234.10        99532-100384
FEATURES             Location/Qualifiers
     source          1..1765
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 30.52 cM"
     gene            1..1765
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /note="ankyrin repeat domain 1"
                     /db_xref="GeneID:107765"
                     /db_xref="MGI:MGI:1097717"
     exon            1..90
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..1023
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /note="cardiac ankyrin repeat protein; cardiac responsive
                     adriamycin protein; ankyrin-like repeat protein; ankyrin
                     repeat domain 1 (cardiac muscle)"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 1"
                     /protein_id="NP_038496.2"
                     /db_xref="CCDS:CCDS29771.1"
                     /db_xref="GeneID:107765"
                     /db_xref="MGI:MGI:1097717"
                     /translation="MMVLRVEELVTGKKNSNGAAGEFLPGEFRNGEYEAAVALEKQED
                     LKTLPANSVKQGEEQRKSEKLREAELKKKKLEQRSKLENLEDLEIIVQLKKRKKYKKT
                     KVPVVKEPEPEIMTEPVDVPRFLKAALENKLPVVEKFLSDKNSPDVCDEYKRTALHRA
                     CLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNADVLKLLLNKGAKISARDKL
                     LSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLMTFGA
                     DLKVKNCAGKTPMDLVLHWQSGTKAIFDSLKENAYKNSRIATF"
     exon            91..270
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /inference="alignment:Splign:2.1.0"
     exon            271..408
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /inference="alignment:Splign:2.1.0"
     exon            409..516
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /inference="alignment:Splign:2.1.0"
     exon            517..615
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /inference="alignment:Splign:2.1.0"
     exon            616..714
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /inference="alignment:Splign:2.1.0"
     exon            715..813
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /inference="alignment:Splign:2.1.0"
     exon            814..912
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1765
                     /gene="Ankrd1"
                     /gene_synonym="Alrp; CARP; Crap; MARP1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccacagggcc agttccaggg gttcatccac aagagagaaa aacatagact cacggctgcc
       61 aacatgatgg tactgagagt agaggagctg gtaacaggca aaaagaacag caatggggcc
      121 gcaggggaat tccttcctgg ggagttcaga aatggagaat atgaagctgc tgttgctttg
      181 gagaagcaag aggacctgaa gacacttccg gccaacagcg tgaagcaggg ggaggaacaa
      241 cggaaaagcg agaaactgcg agaggcagag ctcaaaaaga aaaaactaga acaaagatca
      301 aagcttgaaa acttagaaga ccttgaaata attgttcaac tgaagaaaag gaaaaaatac
      361 aagaaaacca aagttccagt tgtgaaggag ccagaacctg aaattatgac tgaacctgtg
      421 gatgtgccga ggtttctgaa agctgcgctg gagaacaaac tgccagttgt agagaaattc
      481 ctgtcagaca agaacagccc cgacgtctgc gatgagtata aacggacggc actccaccga
      541 gcatgcttag aaggacactt ggcgatcgtg gagaagttaa tggaggctgg agcccagatt
      601 gaattccgag atatgcttga atccacagcc atccactggg catgtcgtgg aggaaacgca
      661 gatgtcctga aactgttgct gaacaaagga gccaaaatca gtgccagaga caagcttctc
      721 agcacagcgc tgcatgtggc ggtgaggact ggtcattacg agtgcgctga gcacctcatc
      781 gcctgcgagg ctgatctcaa tgccaaggac agagaaggag acaccccact gcatgatgct
      841 gtgaggctga accgctataa gatgattcga ctcttgatga ccttcggtgc ggacctcaag
      901 gtcaagaact gtgctgggaa gacccccatg gatctggtgt tgcactggca gagtggaacc
      961 aaagcaatat tcgacagcct caaggagaat gcctacaaga actctcgcat agctacattc
     1021 tgagaaaaga gactcaacag gagctgttcg caggcatttt taaagcattt cccaacagaa
     1081 gagcaactag caataaaatc cagcttttgt ttgccagcca aatagggaga gatgctcaaa
     1141 gaagcttcaa gaaagcactg ggttgtaggt gttaaaatat cctctagtga tgttcaccac
     1201 ttttatttat tcctacctat ttatttattt catagcacca gtattcaggc tttcatgaac
     1261 atcattttgg gggagcaaga cttcatctgt atgtacattc agagtcttcc catagctctt
     1321 aaaccgtgtg ggtgaatggt gtctaattgc acccctttgt gttctcactt gcataaagct
     1381 attcaaggta ctttttaaaa ggcaagggtt gatccccgca gcccttctct gaattctcac
     1441 tgctgatatc tgaatgaagc aacagaaggc acgcagtaac gcagacggga acggaagcag
     1501 ttccgcagga ctggcgcgga ggctcgccac ccacccacag atttggttcg gtttggttgt
     1561 ttaccagatc acatgatgtc gatgtcccaa ggtgaaggca acgtcaggag tgccgcatgt
     1621 agggagatgg agggagtagg caatggggcc aaggaaaact gagttcgatg aaagaagaaa
     1681 tcaaaaggac acgcgctgta aatgtataaa tgtatattgt gttgtatgta tattttatat
     1741 ttataataaa tgcaaactaa ttctc
//
