LOCUS       NM_009671               8034 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ankyrin repeat and FYVE domain containing 1 (Ankfy1),
            mRNA.
ACCESSION   NM_009671
VERSION     NM_009671.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8034)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8034)
  AUTHORS   Chang,L., Soomro,S.H., Zhang,H. and Fu,H.
  TITLE     Ankfy1 Is Involved in the Maintenance of Cerebellar Purkinje Cells
  JOURNAL   Front Cell Neurosci 15, 648801 (2021)
   PUBMED   33796010
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8034)
  AUTHORS   Li,K., Zhang,K., Wang,H., Wu,Y., Chen,N., Chen,J., Qiu,C., Cai,P.,
            Li,M., Liang,X. and Su,D.
  TITLE     Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice
  JOURNAL   Metabolism 114, 154349 (2021)
   PUBMED   32888949
REFERENCE   4  (bases 1 to 8034)
  AUTHORS   Ding,M., Weng,C., Fan,S., Cao,Q. and Lu,Z.
  TITLE     Purkinje Cell Degeneration and Motor Coordination Deficits in a New
            Mouse Model of Autosomal Recessive Spastic Ataxia of
            Charlevoix-Saguenay
  JOURNAL   Front Mol Neurosci 10, 121 (2017)
   PUBMED   28588446
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8034)
  AUTHORS   Weng,C., Ding,M., Chang,L.S., Ren,M.X., Zhang,H.F., Lu,Z.N. and
            Fu,H.
  TITLE     Ankfy1 is dispensable for neural stem/precursor cell development
  JOURNAL   Neural Regen Res 11 (11), 1804-1809 (2016)
   PUBMED   28123425
REFERENCE   6  (bases 1 to 8034)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 8034)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
REFERENCE   8  (bases 1 to 8034)
  AUTHORS   Kannan,K., Kaminski,N., Rechavi,G., Jakob-Hirsch,J., Amariglio,N.
            and Givol,D.
  TITLE     DNA microarray analysis of genes involved in p53 mediated
            apoptosis: activation of Apaf-1
  JOURNAL   Oncogene 20 (26), 3449-3455 (2001)
   PUBMED   11423996
REFERENCE   9  (bases 1 to 8034)
  AUTHORS   Kuriyama,H., Asakawa,S., Minoshima,S., Maruyama,H., Ishii,N.,
            Ito,K., Gejyo,F., Arakawa,M., Shimizu,N. and Kuwano,R.
  TITLE     Characterization and chromosomal mapping of a novel human gene,
            ANKHZN
  JOURNAL   Gene 253 (2), 151-160 (2000)
   PUBMED   10940552
REFERENCE   10 (bases 1 to 8034)
  AUTHORS   Ito,K., Ishii,N., Miyashita,A., Tominaga,K., Kuriyama,H.,
            Maruyama,H., Shirai,M., Naito,M., Arakawa,M. and Kuwano,R.
  TITLE     Molecular cloning of a novel 130-kDa cytoplasmic protein, Ankhzn,
            containing Ankyrin repeats hooked to a zinc finger motif
  JOURNAL   Biochem Biophys Res Commun 257 (1), 206-213 (1999)
   PUBMED   10092534
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL808023.3 and AL663082.5.
            
            On Nov 17, 2006 this sequence version replaced NM_009671.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC139231.1, AB098329.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                AL808023.3         51172-51204
            34-226              AL808023.3         73327-73519
            227-345             AL808023.3         75535-75653
            346-481             AL808023.3         83798-83933
            482-605             AL808023.3         89931-90054
            606-755             AL808023.3         91642-91791
            756-921             AL808023.3         93418-93583
            922-1126            AL663082.5         5761-5965
            1127-1195           AL663082.5         7498-7566
            1196-1395           AL663082.5         7911-8110
            1396-1493           AL663082.5         14365-14462
            1494-1722           AL663082.5         16809-17037
            1723-1821           AL663082.5         17589-17687
            1822-1975           AL663082.5         17910-18063
            1976-2144           AL663082.5         19574-19742
            2145-2263           AL663082.5         21109-21227
            2264-2420           AL663082.5         21846-22002
            2421-2621           AL663082.5         23199-23399
            2622-2798           AL663082.5         24802-24978
            2799-2946           AL663082.5         25962-26109
            2947-3037           AL663082.5         27425-27515
            3038-3162           AL663082.5         27749-27873
            3163-3309           AL663082.5         28872-29018
            3310-3400           AL663082.5         32286-32376
            3401-8034           AL663082.5         35022-39655
FEATURES             Location/Qualifiers
     source          1..8034
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 44.47 cM"
     gene            1..8034
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /note="ankyrin repeat and FYVE domain containing 1"
                     /db_xref="GeneID:11736"
                     /db_xref="MGI:MGI:1337008"
     exon            1..33
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..3533
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /note="ankyrin repeat and FYVE domain-containing protein
                     1; ankyrin repeat hooked to a zinc finger motif; ankyrin
                     repeats hooked to a zinc finger motif; ankyrin repeat
                     hooked to zinc finger motif; rank-5"
                     /codon_start=1
                     /product="rabankyrin-5"
                     /protein_id="NP_033801.4"
                     /db_xref="CCDS:CCDS24989.1"
                     /db_xref="GeneID:11736"
                     /db_xref="MGI:MGI:1337008"
                     /translation="MAEEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCTLLAAQANKE
                     NSNESFISRLLAIVAGLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTE
                     EIDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMS
                     LVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSLSAQLLYKMIKSKT
                     EYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNETDHNGDLALDLALSRRLESIATTLV
                     SHKADVDMVDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYS
                     PKKYSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHLSIMARNDCVFSQLLQCKQL
                     DLELKDHEGSTALWLAVQYITVSSDQSVNPFEDLPVVNGTSFDENSFAARLIQRGSNT
                     DAPDVMTGNCLLQRAAGAGNEAAALFLATSGAHANHRNKWGETPLHTACRHGLANLTA
                     ELLQQGANPNLQTEEALPVPKESPVLMSSADSIYLQTPLHMAIAYNHPDVVSVILEQK
                     ANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQT
                     LLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKHQLPLVVDAICTRGADMS
                     VPDEKGNPPLWLALASNLEDIASTLVRHGCDATCWGPGPSGCLQTLLHRAVDENNEST
                     ACFLIRSGCDVNSPRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNA
                     QDAEGRTPVHVAISNQHSVIIQLLISHPNIELSVRDRQGLTPFACAMTYKNNKAAEAI
                     LKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAV
                     QAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENG
                     NNALHLAVMHGRLNNIRALLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLE
                     CMPEYPLDKPDAEGNTVLLLAYMKGNANLCRAIVRSGVRLGVNNNQGVNIFNYQVATK
                     QLLFRLLDMLSKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIK
                     FDLNKPVRVCNICFDVLTLGGVS"
     exon            34..226
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            227..345
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            346..481
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            482..605
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            606..755
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            756..921
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1126
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1195
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1395
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1493
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1722
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            1723..1821
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            1822..1975
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            1976..2144
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            2145..2263
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            2264..2420
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            2421..2621
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            2622..2798
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            2799..2946
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            2947..3037
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            3038..3162
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            3163..3309
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            3310..3400
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     exon            3401..8034
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7088..7093
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /note="hexamer: AATAAA"
     polyA_site      7112
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /note="major polyA site"
     regulatory      7368..7373
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /note="hexamer: AATAAA"
     polyA_site      7390
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
     regulatory      7975..7980
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
                     /note="hexamer: CATAAA"
     polyA_site      8000
                     /gene="Ankfy1"
                     /gene_synonym="Ankhzn; mKIAA1255; ZFYVE14"
ORIGIN      
        1 ctgtaggcag ggccgggccc gacatggcgg aagaggaggt ggccaagttg gagaagcatt
       61 tgatgcttct aagacaagag tatgtcaagc tgcagaagaa actggcagaa acagagaaaa
      121 gatgcactct tttggctgca caagcaaaca aggagaatag caacgagtca ttcatcagcc
      181 gcttgctggc catagtggca ggtctctatg agcaagagca gtacagtgat ttgaagatca
      241 aggttgggga caggcacatc agtgctcaca agtttgtctt ggccgcccgc agtgatagct
      301 ggagtctggc caatttgtct tccacagagg agatagactt gtcagatgcg aatcctgagg
      361 tgacaatgac aatgcttcgc tggatctata cggatgagtt agagttcaga gaggatgatg
      421 tgttcctgac tgaattgatg aaactggcca atcgctttca gctccagctc cttagggaga
      481 gatgtgagaa gggtgttatg tctctggtga atgttaggaa ctgtattcgc ttctatcaaa
      541 cagcagagga attaaatgcc agtacgctga tgaactattg tgcagaaatt attgcaagtc
      601 actgggatga cttgcgaaag gaggacttca gtagcctgag tgctcagttg ttatacaaaa
      661 tgatcaaatc caagacagag tacccattac ataaagctat caaagtggag agagaagatg
      721 tggtcttcct ctatctgatt gaaatggatt cccagctacc tgggaagctt aacgaaacag
      781 atcataatgg agatcttgcg ttagatctgg ctctttctcg gcgactagag agtattgcca
      841 ccactctggt tagtcataaa gctgatgtgg atatggtaga caaaaatggc tggagcttat
      901 tacataaagg gatccaaaga ggagatcttt ttgcttctac attcctcatt aagaacgggg
      961 cccttgtcaa tgctgccaca gcaggagccc aggagacccc attacacctt gtagcattgt
     1021 acagtccaaa gaaatactca gcagatgtga tgtctgagat ggcacagatt gcggaggccc
     1081 tcctgcaggc tggtgccaac cccaacatgc aggatagcaa gggcaggact cctttacact
     1141 tgtccatcat ggccaggaac gactgtgtgt tcagtcagct gctgcagtgt aaacaattag
     1201 atttagagct gaaagatcac gaaggcagca ctgcactctg gctggccgtc cagtacatca
     1261 ctgtgtcttc agaccagtct gtaaacccct ttgaagacct ccctgtggtg aatgggacat
     1321 catttgatga gaatagcttt gcagccagac tcattcaacg cggcagcaac actgatgctc
     1381 ctgatgtgat gacaggaaat tgtttactac aaagggcagc tggggctgga aatgaggctg
     1441 ctgctctctt cctggcaact agtggtgccc atgccaacca caggaacaaa tggggagaaa
     1501 ctcctttgca tacagcttgt cggcatggcc tggccaacct cacagcagag ctcctgcagc
     1561 aaggtgccaa tccaaactta cagacagagg aggctctgcc ggtacctaaa gagtctcccg
     1621 tcctaatgag ttctgcagac agcatctacc tacaaacacc actgcacatg gcaattgcct
     1681 ataaccatcc agatgtggtt tctgtcatct tagagcagaa agccaatgct cttcatgcca
     1741 ccaacaacct acaaattatt ccagacttca gcctcaagga ttccagagac caaactgttc
     1801 tcggcctggc attatggact ggcatgcaca caatcgctgc ccagctgctg ggctccggag
     1861 cctctatcaa tgacaccatg tcagatggac agacattgct gcacatggcc atacagcggc
     1921 aggacagcaa gagcgctctc ttcctactgg agcaccaagc tgatataaat gtcaggactc
     1981 aggacgggga gactgccctc cagctggcca tcaaacatca gctcccacta gtggttgatg
     2041 ccatatgtac tcgaggagct gacatgtctg tgccagatga aaaagggaac ccaccactgt
     2101 ggcttgcctt ggcaagtaat ctggaggaca ttgcttccac tctggtcaga catggttgcg
     2161 atgctacatg ctggggccca ggacccagtg ggtgtcttca gacacttctg catagagccg
     2221 ttgatgaaaa caatgagtct actgcctgct ttcttattcg cagtggctgt gacgtgaata
     2281 gtcccagaca accaggtact aatggagaag gagaagagga agcaagggat ggacagactc
     2341 ccctgcattt ggcagcctca tggggactag aagagacagt acagtgtctt ttggagtttg
     2401 gtgccaacgt caatgcacag gatgcagaag ggagaacgcc tgtccatgtg gccatcagca
     2461 accagcatag cgtcatcatt cagctgttga tctctcaccc caacattgag ttgagcgtcc
     2521 gggacagaca agggctgact ccttttgcct gtgccatgac ttacaagaac aataaggcag
     2581 ctgaagccat tttaaaacga gagtctgggg ctgctgagca ggtagataat aaaggtcgga
     2641 attttctcca tgtggcagtt cagaactctg acattgaaag tgtcttgttc ctgatcagtg
     2701 tccaggccaa tgtgaactcc agagtccagg atgcttccaa gttgacccct ctgcaccttg
     2761 ctgttcaggc cggctcagag atcattgtcc gaaatctgct tcttgcagga gccaaggtga
     2821 atgagttaac caagcatcgt cagaccgctc tccatctcgc tgcacagcag gacctgccca
     2881 ccatctgctc agtcctccta gagaatggag tggacttcgc tgctgtggat gagaatggaa
     2941 ataatgctct tcatcttgcg gtcatgcatg gtcgactcaa caatatccgg gctcttctga
     3001 cagagtgtac agtagatgct gaagccttta atctgagagg ccagtcacca ctacacattt
     3061 tgggacagta tggcaaagaa aatgcagcag ccatctttga tctcttctta gagtgtatgc
     3121 ctgagtatcc tctggacaaa ccagatgcag aaggcaacac agtgctgctc ttagcataca
     3181 tgaaagggaa tgccaacttg tgccgtgcca tcgttcggtc tggggttcgc cttggggtga
     3241 ataataacca aggagtcaac attttcaact accaggttgc cactaagcag cttctgttta
     3301 gattattaga tatgctctcc aaagagcctc catggtgtga cggctccaac tgctatgaat
     3361 gtactgccaa gtttggagtc acaactcgaa aacatcactg tcgtcactgc ggccgtcttc
     3421 tttgccataa atgctcaacc aaggagatcc ctattataaa gtttgacctg aacaagcctg
     3481 tgcgggtttg caacatttgc tttgatgtac tgactctggg tggagtctct tagtgaggcc
     3541 cccaggagga cccaggcctg catccctggc acctccccag cagctgctct gctcaccggc
     3601 ctgcctccta cccagagcaa gagctggcag ttgtcttcct gcggcagaag accatggcgt
     3661 gatccctgat tgttacaaat gattctgtat gactgtcagt gtgtcagact gtggtctatt
     3721 gcactagatg tctcactggt tggaccaggc cagtttaacc tgcgtgacaa atgtgatagg
     3781 aattggctag cagcacacaa ggacacttgg agacaatgtt cccttccagt aacgtagcgt
     3841 ccatctcaga gaattcacaa agtctccctg cctgggctga ctcagaacag agccctcaga
     3901 gcagagagcg gctgctggat gagcgctggt cactctaggg cggtggctac cctaagaggc
     3961 tctggcctct catgcacagt gttttcataa agagaatagg aacctctgcc ctcaagtctt
     4021 ttctttcttt aagctaagct gtatttttag tgagctgccc ttttaaaaag gtgaaatctt
     4081 tctaacaggg ttcaaagatg agagctgaaa aattgtggcc ttaacaactg aaagctttac
     4141 caatgttgct gctgctgggc gtcagaatgc ctgtggcagc ttgacaccca gcagctgtct
     4201 catctctcgt cttgctgcgt cctgtctttg gagtcctcgg tcgctgccac ttgagtggtg
     4261 gaagaaatgc actttgactg tgctgcactt ttctagctgt gtcattggtg aatccaattc
     4321 aaaaacccat gttcaagaat gccatcacat gctcttccat cagtggttct gatagccagc
     4381 ttggactgga cctcagcaca cactaatcta aaagggaaaa ctgccaagaa ggaagaaatt
     4441 catactgata agaaaggaga tagctgtgac tttgatccag gttctctctc cctgacacat
     4501 ccttcctgct aaaaccttgc cttgcatgct gagtgctagt ggcaccagtt ctgggtggcg
     4561 ctgtgcctca tcagagctga acagcccaag gccccggcca gctatgagca gcctgtttta
     4621 gagctctgtc tgaaatgatg agcgaggcta cgaagcatag gtctttggtt cctgctgctg
     4681 ccgcctgttc tacccctggg atgcggggcc tctttcttct taaagtttgg ccagtgtttt
     4741 gggttgtttc tgtttgggaa ttttaatttt ttcattttat tatattgcac actgaaagag
     4801 aaacttacac cactgggttt tctgtttgtt tttaagaaac aaaaccacaa ttgctctgag
     4861 actctgagat gaacagtatc tggtcatagt cagagcttaa ctgtcaatca ctcgcactga
     4921 tttttttgag acatttgata accctacgat acttgcgtta atagagtatg gctgtatgaa
     4981 taaaagggac ttcttttggc atcactttct tccttggata gtggtatgct ctctgttgct
     5041 gtagagttag acatcttact gcctaaatat gtataaaatg tgctgagaaa ccagtgtgct
     5101 actttctaaa aatatttctg tgatttatat gtatgctttt tatgttaaca ttagcttgta
     5161 cacagtgttt aaaaggaaga gttacttgga ggagtgccat tgtcccccag cctgtgactt
     5221 acttcatata taatctttat ggaaacattt aatcagtctt ggccaacaac tataggagca
     5281 tgtagtcagt ttccaggttt tattgcctaa aaagggccac gaagacctag agttaggttg
     5341 ttaccgtggt tctttagtgg gaaaggtagg aatggtatgg ttatgaacca gggtggaaag
     5401 ggcacatagg gaagcaggat gacgctgatc attgtgtcct tgccctacca caccagtttc
     5461 agtaacaacc ttgcctataa ctgtacttac aatttgcaga tgatgcctaa agcatatgta
     5521 ggttcaagct tctgttcctt cagaggtcat tgtagtcatc cccgtggctg acggggctgt
     5581 gtgacttgag cattggtagc catgctgtag atgtggctca ggctttcttc cacagccgca
     5641 atcccccaga ccatgccatg ctcactgtgc tgccctcctg ctgtacactg ccctggccag
     5701 gaccagactt actgtgtgtc tctcctgtgc tctctccatg ctgaccagat ttcaccatga
     5761 aattgcttac ctgttcttgt tcggtcttat cactacctta agaactagca gcaaaacttc
     5821 atttattcat tcaaaaagtt gttggttgtg aatgagccaa tcaggaagaa tcaagtttac
     5881 tgaaacataa ttgctgcatc agttaacact gctatactca cctagctttt tacctgcctc
     5941 ttgttcatca tgactgctgt acagtgtatc attaaggttt taaagataga ggtacagacc
     6001 atgtgcttac actagtttgc tatgatcttc taacacagca atgtcccaca agcttaagtg
     6061 cctacactga ggactccctt gtttccagtt gtcttttcat tggtgtctca ctcagtgatg
     6121 tgttagaaca cgagtttcgg gcctattcca ccccagtagc caattcagtc cagtctgaat
     6181 attagactgc tcagttcatc tgccatattc tctccaagga gtggggtcca catgatgttt
     6241 ctgtcctcta cctcagaacc atgagttgtt tctgactacc catcagcttc ctccctctcc
     6301 ttgagtgggt ctttcatgaa gctgggtgtg tggaatctca ccaccccgcc caatttgcgc
     6361 ccatccccca tactgaaccg ttcctgtact agtcttgttt gcaggcaagg ggtggaagac
     6421 aggcccccat ctaggatttc cttacctgga gaagagaaaa agtggctgaa ctgccaaatg
     6481 cttaggagag gaagcaacag cagcatgtaa atgtctccct cacagatgct ggcttccctc
     6541 aggatcagcc cctagagcca cctgaagctc cagagctccc ctgccagccc agcagaggaa
     6601 gcagctcagc aaaggcctct gagctatgct cactatacag aactgatata gtgaaaaacc
     6661 agctaactaa atataaaatt cccagatgtc atagatgcct taaagacttt tctcgggagg
     6721 atcattgcct cttgtgtgga ataaataatg tattaactct tacaaccgac aacattggtt
     6781 ttccacagtg agggagtctg gggactgctg gacttactga cttgccagtt tggcagctgt
     6841 gtggaactgg gcgttccatg atatcttatg gtaccaagga caaggtggca gcagctgggc
     6901 cataactgca ggcacgtgtt tgtatagacc actttggctc tcaaactgct ctggtgctgc
     6961 tcagtgtggg atgaccgcat cagctgggac catggctaag gcttagcagc attgtttctt
     7021 tggattctgt gtaatggaat gtatttttca aatattgata ttttgatttt ctgtaataat
     7081 tccttacaat aaaaatgagg taaaattgta aatttaaagt gtaaacttta attaaagaca
     7141 tttatagcta cttctaagtc agaagtacca gtaaacatta aaaaacagtt tctaaaaatt
     7201 gataatgtga gggctggaga gttggctcag cggttaagaa taatgctaca gatgacctgg
     7261 gttccattcc cagctctcat gtggaggctc aaagccgcct caggcaccag gtatacaagt
     7321 gatatacaga gatgtacatg taggcaaaac actcataccc atgaaataat aaaagtaaat
     7381 ctgaacaata catttaaaag tggtttgtgg acaaatgtct tgaacagcta ccctccacat
     7441 ttcctattct agcatcccat gtgacacata ctgacagacc tcaccagcgt tctgtgcaga
     7501 gtgagcaact gctgcatccc tgcctctcca gtgcaagctt tactttatgg ttgcacatgt
     7561 gactgctgat gcagaatcag ctgtctgaca ccatggaagc tgtccaaaga atcctagacg
     7621 cctttactcc attatttaaa agcaactata aatattcacc aatgatgagc ttcctacagg
     7681 ccaagattta aaagggtggg gacggggtga tagcactgtg ggcgtcagat aacatcaggg
     7741 aatgtttaga agtctgcaga ttaaaatctg gttcatgggg ctggtgagat ggctcagtgg
     7801 gtaagagcac ccgactgctc ttccgaaggt ccagagttca aatcccagca accacatggt
     7861 ggctcacaac catccgtaac aagatctgac tccctcttct ggtgtgtctg aagacagcta
     7921 cagtgtactt acatataata ataaaaataa ataaaattta aaaaaaatct ggttcataaa
     7981 gccctgatca agtctagtac caaaaataaa aatctagtga gtgaaccttc agaa
//
