LOCUS       NM_144524               3867 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus angel homolog 1 (Angel1), mRNA.
ACCESSION   NM_144524
VERSION     NM_144524.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3867)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3867)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY194341.1, AK143549.1, CF173918.1 and BQ175854.1.
            
            On Dec 19, 2007 this sequence version replaced NM_144524.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143549.1, SRR1660819.171327.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                BY194341.1         3-81
            80-1811             AK143549.1         81-1812
            1812-2157           CF173918.1         206-551
            2158-3638           AK143549.1         2163-3643
            3639-3849           AK143549.1         3645-3855
            3850-3867           BQ175854.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..3867
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 40.86 cM"
     gene            1..3867
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /note="angel homolog 1"
                     /db_xref="GeneID:68737"
                     /db_xref="MGI:MGI:1915987"
     exon            1..131
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..2071
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /codon_start=1
                     /product="protein angel homolog 1"
                     /protein_id="NP_653107.2"
                     /db_xref="CCDS:CCDS26067.1"
                     /db_xref="GeneID:68737"
                     /db_xref="MGI:MGI:1915987"
                     /translation="MIASCLYYLLLPAARLFRFLSDAFFTCRKNALLAKSSSPQVEGN
                     FAMAPRGPDQEECEGLLQQWREEGWNQTPSTASEGPLADKGLAESSLALLMDNSGEQD
                     AASEDKWSSRQLSDLRAAENLNQPFPEVLGEEPLAEVEGPLWAAVPVQTGPQYADCAV
                     LPMGAMAAEQWEEDPAMVAWSIAPEPMPQEETSMWPFEGLEQLQPPPMEIPYHEILWR
                     EWEDFSTQPDAQGLEAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRF
                     ANLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMGFTCFYKRRTGCKTDGCAVCYK
                     PTRFRLLCASPVEYFRPGLELLNRDNVGLVLLLQPLVPEGLGQVSVAPLCVANTHVLY
                     NPRRGDVKLAQMAILLAEVDKVARLSDGSHCPIILCGDLNSVPDSPLYNFIRDGELQY
                     NGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSERLKYGRDF
                     LLRFRFCDLACQRPVGLVLMEGVTDTKPDRPAGWAECIFEEEISELEPVFPRTIGTIQ
                     HCLHLTSVYTHFLPQHGCPEVTTMPLGLGMTVDYIFFSAESCENENRTDHRLDRDGTL
                     KLLGRLSLLSEEILWAANGLPNPFYSSDHLCLLASFGMEVTAP"
     exon            132..707
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     exon            708..934
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     exon            935..1004
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1438
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     exon            1439..1565
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     exon            1566..1676
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1746
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     exon            1747..1910
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     exon            1911..3850
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3827..3832
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /note="hexamer: AATAAA"
     polyA_site      3850
                     /gene="Angel1"
                     /gene_synonym="1110030H02Rik; mKIAA0759"
                     /note="major polyA site"
ORIGIN      
        1 ggggtcgaac agaggagacc ggtgtgcagc agtgtggagg ggcggcggcg cgggcaggca
       61 gccggccatg atcgcgtcgt gcctgtatta cctgctgctg ccagccgcgc gcctcttccg
      121 ctttctctca gatgctttct ttacatgtcg aaaaaatgcc cttctggcga agagctcatc
      181 tccccaggta gagggtaact ttgccatggc ccctcggggg cctgaccaag aagagtgtga
      241 gggcctgctg cagcagtggc gagaagaagg gtggaaccag acaccctcaa ctgcaagcga
      301 gggtcccctt gcggataagg gactagctga gagcagtctg gccctcctga tggataattc
      361 tggagaacag gatgctgcct cggaggacaa gtggtccagc aggcagctga gtgaccttcg
      421 ggcagcagag aacctgaacc agcctttccc tgaggtgcta ggggaggagc ctctggccga
      481 ggttgagggt cctttgtggg cggctgttcc ggtacagaca gggccccagt atgcagattg
      541 tgctgttctt ccaatgggtg cgatggccgc agaacagtgg gaagaggacc ctgcaatggt
      601 ggcctggagc atagcaccgg agcctatgcc ccaggaggag acttccatgt ggccctttga
      661 aggcctggaa cagctgcagc ctcccccaat ggaaatacct tatcatgaaa tcctgtggcg
      721 agaatgggag gatttctcca cacagccaga tgctcagggt ctggaggcag gagacggccc
      781 tcagttccag ttcactctga tgtcgtataa tatcctggcc caggacctga tgcagcagag
      841 ctcagagctc tatctgcatt gccatccaga catcctcaac tggaattacc gctttgccaa
      901 cctcatgcag gaattccagc actgggaccc ggatatcctg tgtcttcagg aagtccagga
      961 agaccactac tgggagcagc tggagccctc tctgcggatg atgggcttca cctgttttta
     1021 caagaggagg actgggtgta aaacggatgg ctgtgctgtg tgctacaagc ccaccaggtt
     1081 ccgtctgctc tgtgccagcc ctgtggagta cttccggcct gggttggagc tcctcaaccg
     1141 ggacaatgtg ggcttagtgt tgctgctgca gccgctagtg ccagaaggtc tggggcaagt
     1201 ctcagtggct cccctgtgtg tggcaaatac ccatgtcctg tacaacccgc gtcggggtga
     1261 tgtcaagctg gcccagatgg ccattcttct ggccgaggtg gacaaggtgg ccaggttgtc
     1321 agatggcagc cactgcccca tcatcttgtg tggggacctg aattctgtcc ctgactcacc
     1381 tctctacaac ttcatcaggg atggagagct ccagtacaat ggcatgccag cctggaaggt
     1441 ttctggacag gaagacttct ctcatcagct ttaccagagg aagctgcagg ccccactgtg
     1501 gcccagctcc ctgggcatca ctgactgctg tcaatatgtc acctcctgtc atcccaagag
     1561 atcagagaga ctgaaatatg gccgagactt cctactacga ttccgcttct gtgacctcgc
     1621 ttgccagcga ccagtgggac tggttctaat ggaaggagtg acagacacta agccagatcg
     1681 acctgctggt tgggccgagt gtatctttga ggaagagata tctgaacttg agcctgtctt
     1741 ccccaggact ataggcacca tccagcactg cctccacctg acctcagtgt atacccactt
     1801 cctgccccag catggctgcc cagaggtcac cacgatgccc ttagggcttg ggatgacagt
     1861 ggattacatt ttcttctcag ctgaatcctg tgagaatgag aacagaaccg atcacagact
     1921 ggatcgagat ggaactctca agctcctggg ccgcctctcc ctcctctctg aagagattct
     1981 ctgggctgcc aatggcttac ccaacccctt ctactcttca gaccatctct gcttgcttgc
     2041 cagcttcggc atggaagtca ctgccccatg aggggcccca gggaaagagc tcactggacc
     2101 gacgactgca aatgccccgt gctgtggaaa cttccgtccc ttccctcgtc ccctcctgcc
     2161 cgtggttaga ctttctccag gcctgtccac gttcttggcc tgtggtccct gccctgcccc
     2221 aacctcttcc taatcctggg ccacatgcta ggtggcccct cgagaggtgg agaatactcc
     2281 cctttcttcc atgtacccag cacccctccc cccattgatt tttttttaat gaccagggtt
     2341 gcgggagtta ttgatctcat tggttattcg ctttcaggcc atttcttggt ggcaccctct
     2401 gacccaacct tccctttcct ttcatgacct ctgggctctg gcatgcacat gagcaaggtg
     2461 tgtgtaaagc gtgagttctc ttggagcggg actgcccagc acagccaaag cctacctctg
     2521 cctagtccat gtgctaccta tcatgagctg ctgggctaga cacaggttga aagcatgaca
     2581 tagtagctgt gtgctgccgg gaagcagcag gtgtggggcc cttctctccc agtcagtcat
     2641 ctcagcatcc tgggcacact tgttatttct ggagacaaat tggcccccag cctggagcaa
     2701 gcagctcagg gatgccctaa cctcagatct cctcactgcc ttccttgagg aaagcgggtg
     2761 gatgccttgt gctggggttc actgggctgg cacagtgctg ggaggctatg gcatttgaag
     2821 ggtgaggaga ctgagccttc agggaactgt tgtctcacca gactctgaag aactgggtaa
     2881 gagttggagt cccagcagaa agagcaggag gctctacagc agccttggcc agcactggag
     2941 ccccagaggg cttgatctct gacctctgcg tacctaagaa agtttctttt cttcttctct
     3001 ctcctcctcc tcccctcctt tgttccctcc cattttctct ctggagaagc ccgctgttta
     3061 gctcaggcca aaacatctca acagaagcct ggcttggggc aaactaggtc taagaactca
     3121 gggtggcagt gcttgcccat gtgctctgcc ttttcctccc caaacatggg ctccgcccgc
     3181 tcccctaacc tactgaaaac ccctgcagcc cagaccgtgt cacctgcatg ccttactcac
     3241 tgctggggtg cagcctaggg tgacctcagg ccagagcctc cacatagctt caactcagaa
     3301 gatctgctgg cccagagatg aggggattga ctgaggctgc agttaggcat ggtggagcag
     3361 cagttacacc cttcccttga gttgaaagcc agagacctgt ctggaatgct gctgctgctg
     3421 ctgctgctgc tgcgttgctg actctcagct tcccatgctc aggtctgggg gacgtctttt
     3481 cttatgtgtg tcttattttt aagttttgtt atctgggtac tggacatctg cctgtctgag
     3541 ccccaggccc atctgtctgt ccacagccca cttttcaccg tcactctctg ggcacctcct
     3601 gagatggttc cacaaccgtg ccctgttggt tctcagaaca ggggccaatg attgttcccc
     3661 ctgccaggaa atgcaggttc aactgctaaa ggaggcagag ggtcagagct tggtggttta
     3721 tcttttcctt gtttctcctt gtttctgttt tagaaatgaa gtgtgggggt ttaaatggca
     3781 cttaaactgc accctggagc cggcagaacc aggcaacgtt tttccaaata aaggcttacc
     3841 atgcccccta aaaaaaaaaa aaaaaaa
//
