LOCUS       NM_001357234            2811 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus anaphase promoting complex subunit 10 (Anapc10),
            transcript variant 2, mRNA.
ACCESSION   NM_001357234 XM_006531339
VERSION     NM_001357234.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2811)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2811)
  AUTHORS   Saito,K., Michon,F., Yamada,A., Inuzuka,H., Yamaguchi,S.,
            Fukumoto,E., Yoshizaki,K., Nakamura,T., Arakaki,M., Chiba,Y.,
            Ishikawa,M., Okano,H., Thesleff,I. and Fukumoto,S.
  TITLE     Sox21 Regulates Anapc10 Expression and Determines the Fate of
            Ectodermal Organ
  JOURNAL   iScience 23 (7), 101329 (2020)
   PUBMED   32674056
REFERENCE   3  (bases 1 to 2811)
  AUTHORS   Zhao,S., Gou,L.T., Zhang,M., Zu,L.D., Hua,M.M., Hua,Y., Shi,H.J.,
            Li,Y., Li,J., Li,D., Wang,E.D. and Liu,M.F.
  TITLE     piRNA-triggered MIWI ubiquitination and removal by APC/C in late
            spermatogenesis
  JOURNAL   Dev Cell 24 (1), 13-25 (2013)
   PUBMED   23328397
REFERENCE   4  (bases 1 to 2811)
  AUTHORS   Ray,D., Hogarth,C.A., Evans,E.B., An,W., Griswold,M.D. and Ye,P.
  TITLE     Experimental validation of Ankrd17 and Anapc10, two novel meiotic
            genes predicted by computational models in mice
  JOURNAL   Biol Reprod 86 (4), 102 (2012)
   PUBMED   22190705
  REMARK    GeneRIF: ANAPC10 was mainly expressed in the cytoplasm of
            spermatogonia and leptotene and pachytene spermatocytes.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2811)
  AUTHORS   Wise,T.L. and Pravtcheva,D.D.
  TITLE     Oligosyndactylism mice have an inversion of chromosome 8
  JOURNAL   Genetics 168 (4), 2099-2112 (2004)
   PUBMED   15611179
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158348.4, BB647573.1 and AC101714.10.
            
            On Oct 24, 2017 this sequence version replaced XM_006531339.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB574494.1, SRR9219383.21704.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AC158348.4         116024-116073
            51-531              BB647573.1         1-481
            532-2811            AC101714.10        61977-64256
FEATURES             Location/Qualifiers
     source          1..2811
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 37.79 cM"
     gene            1..2811
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /note="anaphase promoting complex subunit 10"
                     /db_xref="GeneID:68999"
                     /db_xref="MGI:MGI:1916249"
     exon            1..82
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /inference="alignment:Splign:2.1.0"
     exon            83..209
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..652
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /note="isoform 1 is encoded by transcript variant 2;
                     cyclosome subunit 10"
                     /codon_start=1
                     /product="anaphase-promoting complex subunit 10 isoform 1"
                     /protein_id="NP_001344163.1"
                     /db_xref="CCDS:CCDS22439.1"
                     /db_xref="GeneID:68999"
                     /db_xref="MGI:MGI:1916249"
                     /translation="MTTPNKTPPGADPKQLERTATVREIGSQAVWSLSSCKPGFGVDQ
                     LRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNF
                     HNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYT
                     PVEESSIGKFPRCTTIDFMMYRSIR"
     exon            210..300
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /inference="alignment:Splign:2.1.0"
     exon            301..421
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /inference="alignment:Splign:2.1.0"
     exon            422..2811
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      808..813
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /note="hexamer: AATAAA"
     polyA_site      840
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /note="major polyA site"
     regulatory      871..876
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /note="hexamer: ATTAAA"
     regulatory      876..881
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /note="hexamer: AAGAAA"
     polyA_site      893
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
     polyA_site      898
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
     regulatory      2791..2796
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
                     /note="hexamer: AATAAA"
     polyA_site      2811
                     /gene="Anapc10"
                     /gene_synonym="1500026N15Rik; A830003M23Rik; APC10"
ORIGIN      
        1 gccaatgaac tgagggagcc tagaatcgtc gagccgcagt gggagtggcg ggggcctgag
       61 aaccggaatt gtggcgaatc agaataattt aaaaatgacc acaccgaaca agacacctcc
      121 tggtgctgat cctaagcagt tggagaggac agcaacagtc agggaaattg ggtctcaggc
      181 tgtttggtca ctctcttcct gcaaaccagg gtttggagtg gatcaattac gggatgacaa
      241 tctagaaact tactggcaat ctgatggctc tcagcctcac ttagtgaaca tccaattcag
      301 aagaaaaaca acagtgaaga cattatgtat ttatgcagac tataagtctg atgaaagcta
      361 cactccaagc aaaatctcag tcagagtagg aaataatttt cacaaccttc aagaaatccg
      421 gcaacttgaa ttggtggaac caagtggctg gattcacgtt cctttaactg acaatcataa
      481 gaagccaact cgcacattca tgatacagat tgctgttcta gccaatcatc agaatggaag
      541 agatacccac atgagacaaa ttaagatata cacaccagtg gaagagagct ccattgggaa
      601 attccctaga tgcacaacca ttgatttcat gatgtatcgt tcaatacggt gactttaaaa
      661 tggacagaag tgaacagacg tttgttttat cctatcattg gatagtatat caagtatctt
      721 tggtgaaaag tcatgttact ttgcaatttt acatacattt aaaataattt agataaataa
      781 cttttaggtc atgtctgttt tttatataat aaagctcata ttttatgttg ctaacatgaa
      841 tttgaagtca atctttaaat ttttctttat attaaaagaa aactagttaa actgaaaatt
      901 tcaagatata tatactatgt gtttacttta tttatggtgg ttatttcata taatggttgt
      961 tggatattgg gagcaaaatg gaattttcaa tagcactgaa gtggaagctt aaaggtactt
     1021 tggaatatta gttgtgttgg atggtgtttt cctggagcag acacaggtga aagaccaagg
     1081 aacatttggc tgaaacagac ccaggtatgt tctgctaaag caagcatgtg agagggctct
     1141 gagtgaagac attcatgtat tggtcctcct tacattgcat agttgagctg catttgttgg
     1201 gactcttaac accaaaacct tctggtggtg tgctactgct tcttgttgct tctgcagatt
     1261 tgggctgatt ggcagagacc tgtcacctga gacatactta atgtgctgaa gcaaagcatg
     1321 tgctgagaca ataacatgtg gaggacactt gatgtctgga gagatgataa ataggactca
     1381 caatgacgga ggctgaacta gtcttgctta tagagctgtc tgtgcaacgc ttgagaggca
     1441 cagctgagag cttttcctgg tgttcctgtt ggccatggtc cttcctgttg actagtgcca
     1501 gagctgaggc ctggctgtct ctgctaggta gtgccatcgc tgctgattgg tgtttgctat
     1561 cctgacttct gtgaactgaa ctgctgattt cctgacaatg cagatgggag ttgctctaaa
     1621 gaaccatatc ttaaacaaat ctacttcccc tgtgttcttt ccttccacta cttatggtgg
     1681 atggaaggct aaaaggaagg ttaaagcatt taagaaccct catttaaaaa aaggcttgaa
     1741 aaaattaaag ttacacatta attttttttt tagaggaaat taaatgtttg tgtcccccct
     1801 cacccgaaac aatgataatt caatctctgg gtgcaacaac tagaatccta atcttgtaag
     1861 ccatattaaa tctaaatcct caggtggcaa atcctggcag attcgccatt taagctgagg
     1921 acactagtag ctacatcttg ccttctcgat aaccctgtcc aaatagcccc taactctcct
     1981 gcttcctctc ttcctctgtc caaccttgaa gtctcaccta cttgcccagt gattggtccc
     2041 tgtattcaga cagcccctcc tgggaaagca gaattaacat cgtaagtgga attaatacag
     2101 gcatcaccag ggccatccac aacactttcc tttttctgta ctaataaaaa acaaaacttt
     2161 tctctcaaat ataaattgag cacaactact accattttgt aatttataaa gtacaagata
     2221 gacctaacac ccagtcagtc catcattttt gtcaattaaa tagaacactg tcatatttcc
     2281 taacttaaaa gacgtataat tctacacctg acttatgtcc tggctttaga ttgtatgcca
     2341 tctgaaaacc atcctcaaat ctgttttatc aatgttaaat agcctgggtt ggctttgaga
     2401 ctataagtag tctttcaact ccatcagaaa tccgagaatg accaacatta tctgaagata
     2461 aaggaagcct aacacagctt ccagacctga gacaagttgt agagacagct gcctacccat
     2521 atagccccag taagtcagga agttggagca tcaatcttca tcctctggcc cagaatcatc
     2581 tgacagatct ttgaaaaaca ggaattgtta aggattagcc tattgtctca gcagaactaa
     2641 gctgtcctaa cctgaacatt gtgtccttag atagccagtt tctgctcagt ggccacctgg
     2701 ccacagtgta tcacttcact tggaggtata gatgctctgt tgctttgaat ccatgaatga
     2761 gaagctgtta ggagattatc tcaggaagtg aataaataac attaaatgtc a
//
