LOCUS       NM_001042711            1577 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus amylase 2a5 (Amy2a5), mRNA.
ACCESSION   NM_001042711 NM_001042712 NM_009669
VERSION     NM_001042711.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1577)
  AUTHORS   Cobo,I., Paliwal,S., Bodas,C., Felipe,I., Melia-Aloma,J.,
            Torres,A., Martinez-Villarreal,J., Malumbres,M., Garcia,F.,
            Millan,I., Del Pozo,N., Park,J.C., MacDonald,R.J., Munoz,J.,
            Mendez,R. and Real,F.X.
  TITLE     NFIC regulates ribosomal biology and ER stress in pancreatic acinar
            cells and restrains PDAC initiation
  JOURNAL   Nat Commun 14 (1), 3761 (2023)
   PUBMED   37353485
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1577)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1577)
  AUTHORS   Mamidi,A., Prawiro,C., Seymour,P.A., de Lichtenberg,K.H.,
            Jackson,A., Serup,P. and Semb,H.
  TITLE     Mechanosignalling via integrins directs fate decisions of
            pancreatic progenitors
  JOURNAL   Nature 564 (7734), 114-118 (2018)
   PUBMED   30487608
REFERENCE   4  (bases 1 to 1577)
  AUTHORS   Magdeldin,S., Li,H., Yoshida,Y., Satokata,I., Maeda,Y.,
            Yokoyama,M., Enany,S., Zhang,Y., Xu,B., Fujinaka,H., Yaoita,E. and
            Yamamoto,T.
  TITLE     Differential proteomic shotgun analysis elucidates involvement of
            water channel aquaporin 8 in presence of alpha-amylase in the colon
  JOURNAL   J Proteome Res 9 (12), 6635-6646 (2010)
   PUBMED   20939500
  REMARK    GeneRIF: Studies confirmed the involvement of AQP8 in alpha-amylase
            2 regulation.
REFERENCE   5  (bases 1 to 1577)
  AUTHORS   Kedees,M.H., Guz,Y., Vuguin,P.M., Vargas,C., Cui,L., Steiner,D.F.,
            Charron,M.J. and Teitelman,G.
  TITLE     Nestin expression in pancreatic endocrine and exocrine cells of
            mice lacking glucagon signaling
  JOURNAL   Dev Dyn 236 (4), 1126-1133 (2007)
   PUBMED   17366624
REFERENCE   6  (bases 1 to 1577)
  AUTHORS   Wilkie,T.M., Gilbert,D.J., Olsen,A.S., Chen,X.N., Amatruda,T.T.,
            Korenberg,J.R., Trask,B.J., de Jong,P., Reed,R.R., Simon,M.I. et
            al.
  TITLE     Evolution of the mammalian G protein alpha subunit multigene family
  JOURNAL   Nat Genet 1 (2), 85-91 (1992)
   PUBMED   1302014
  REMARK    Review article
REFERENCE   7  (bases 1 to 1577)
  AUTHORS   Haefliger,J.A., Bruzzone,R., Jenkins,N.A., Gilbert,D.J.,
            Copeland,N.G. and Paul,D.L.
  TITLE     Four novel members of the connexin family of gap junction proteins.
            Molecular cloning, expression, and chromosome mapping
  JOURNAL   J Biol Chem 267 (3), 2057-2064 (1992)
   PUBMED   1370487
REFERENCE   8  (bases 1 to 1577)
  AUTHORS   Dower,N.A., Seldin,M.F., Pugh,S. and Stone,J.C.
  TITLE     Organization and chromosomal locations of Rap1a/Krev sequences in
            the mouse
  JOURNAL   Mamm Genome 3 (3), 162-167 (1992)
   PUBMED   1617222
REFERENCE   9  (bases 1 to 1577)
  AUTHORS   Siracusa,L.D., Jenkins,N.A. and Copeland,N.G.
  TITLE     Identification and applications of repetitive probes for gene
            mapping in the mouse
  JOURNAL   Genetics 127 (1), 169-179 (1991)
   PUBMED   1673105
REFERENCE   10 (bases 1 to 1577)
  AUTHORS   Lane,P.W. and Eicher,E.M.
  TITLE     Gene order in linkage group XVI of the house mouse
  JOURNAL   J Hered 70 (4), 239-244 (1979)
   PUBMED   489953
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK133526.1.
            
            On or before Nov 5, 2009 this sequence version replaced
            NM_009669.2, NM_001042712.1, XM_001481315.1, XM_001481336.1,
            NM_001042711.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.158292.1,
                                           SRR5189673.188549.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1577              AK133526.1         2-1578
FEATURES             Location/Qualifiers
     source          1..1577
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 49.35 cM"
     gene            1..1577
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /note="amylase 2a5"
                     /db_xref="GeneID:109959"
                     /db_xref="MGI:MGI:88020"
     exon            1..185
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..1544
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /EC_number="3.2.1.1"
                     /note="amylase 2a5, pancreatic; pancreatic alpha-amylase;
                     PA; 1,4-alpha-D-glucan glucanohydrolase; amylase 2,
                     pancreatic; pancreatic alpha-amylase 2a5"
                     /codon_start=1
                     /product="pancreatic alpha-amylase 2a5 precursor"
                     /protein_id="NP_001036176.1"
                     /db_xref="CCDS:CCDS17775.1"
                     /db_xref="GeneID:109959"
                     /db_xref="MGI:MGI:88020"
                     /translation="MKFVLLLSLIGFCWAQYDPHTSDGRTAIVHLFEWRWVDIAKECE
                     RYLAPKGFGGVQVSPPNENVVVHNPSRPWWERYQPISYKICTRSGNEDEFRDMVTRCN
                     NVGVRIYVDAVINHMCGAGNPAGTSSTCGSYLNPNNREFPAVPYSAWDFNDNKCNGEI
                     DNYNDAYQVRNCRLTGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDAAKHMWPGD
                     IKAVLDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGT
                     VIRKWNGEKMSYLKNWGEGWGLVPSDRALVFVDNHDNQRGHGAGGSSILTFWDARMYK
                     MAVGFMLAHPYGFTRVMSSYRWNRNFQNGKDQNDWIGPPNNNGVTKEVTINADTTCGN
                     DWVCEHRWRQIRNMVAFRNVVNGQPFSNWWDNNSNQVAFSRGNRGFIVFNNDDWALSA
                     TLQTGLPAGTYCDVISGDKVDGNCTGLRVNVGSDGKAHFSISNSAEDPFIAIHADSKL
                     "
     exon            186..332
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            333..521
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            522..752
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            753..886
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1009
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1109
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1228
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1354
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1577
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1577
                     /gene="Amy2a5"
                     /gene_synonym="1810008N23Rik; Amy-2; Amy2; mAmy2-2"
                     /note="putative"
ORIGIN      
        1 gacaacttca aagcaaaatg aagttcgttc tgctgctttc cctcattggg ttctgctggg
       61 ctcaatatga cccacatact tcagatggga ggactgctat tgtccacctg ttcgagtggc
      121 gctgggttga tattgccaag gaatgtgagc gatacttagc tcctaaggga tttggagggg
      181 tgcaggtctc tccacccaat gaaaacgttg tagttcataa cccatcaaga ccttggtggg
      241 aaagatacca accaatcagc tataaaatct gcacaaggtc tggaaatgaa gatgaattca
      301 gagacatggt gacaaggtgc aacaatgttg gtgtccgtat ttatgtggat gctgtcatta
      361 accacatgtg tggcgcaggc aatcctgcag gaacaagcag tacctgtgga agttacctca
      421 atccaaataa cagggaattc ccagcagttc catactctgc ttgggacttt aacgataata
      481 aatgtaatgg agaaattgat aactacaatg atgcttatca ggtcagaaat tgtcgtctga
      541 ctggccttct ggatcttgca cttgagaaag attatgttcg taccaaggtg gctgactata
      601 tgaaccatct cattgacatt ggagtagcag ggttcagact tgatgctgct aagcacatgt
      661 ggcctggaga cataaaggca gttttggaca aactgcataa tctcaataca aaatggttct
      721 cccaaggaag cagacctttc attttccaag aggtcattga tctgggtggt gaggcaatta
      781 aaggtagtga gtactttgga aatggccgtg tgacagaatt caagtatggt gcaaaacttg
      841 gcacagttat ccgcaagtgg aatggcgaga agatgtccta tttaaagaac tggggagaag
      901 gttggggttt ggtgccttct gacagagccc ttgtgtttgt ggacaaccat gataatcagc
      961 gaggacatgg tgctggagga tcatccatcc tgacattctg ggatgctaga atgtataaaa
     1021 tggctgtcgg atttatgttg gctcatcctt atggattcac aagagtaatg tcaagttacc
     1081 gttggaatag aaatttccag aatggaaaag atcagaatga ctggattgga ccacccaata
     1141 acaatggagt aacaaaagaa gtgaccatta atgcagacac tacttgtggc aatgactggg
     1201 tctgtgaaca cagatggcgt caaatcagga acatggttgc cttcaggaat gtggtcaatg
     1261 gtcagccttt ttcaaactgg tgggataata acagcaacca agtagctttt agcagaggaa
     1321 acagaggatt cattgtcttt aacaatgatg actgggcttt gtcagccact ttacagactg
     1381 gtcttcctgc tggcacatac tgtgatgtca tctctggaga taaggtcgat ggcaattgca
     1441 ctggacttag agtgaatgtt ggcagtgatg gcaaagctca cttttccatt agtaactctg
     1501 ctgaggaccc atttattgca atccatgctg actcaaaatt gtaagaatct atattaaaga
     1561 gatttggatt aagcatc
//
